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Table 1 Neutrophils and macrophages were counted based on HE staining. Results are presented as the mean ± SD per high-power field, n = 3

From: Targeting myeloperoxidase to stabilize unruptured aneurysm: an imaging-guided approach

Group

Inflammatory cells

Neutrophils

Macrophages

ABAH(+) Week 1

1 ± 1

0

ABAH(+) Week 4

1 ± 1

1 ± 1

ABAH(-) Week 1

87 ± 7

15 ± 6

ABAH(-) Week 4

7 ± 4

8 ± 6

  1. At week 1, vessel wall integrity in the ABAH(+) group was largely unaltered compared to substantial loss of the internal elastic lamina (IEL) and tunica intima in the ABAH(-) group (Fig. 5, A). At week 4, pronounced vascular fibrosis occurred in both groups, but only the ABAH(-) group showed abundant calcification foci and poor elastin regeneration (Fig. 5, A)