Fig. 1
From: APOE ε4 carriage associates with improved myocardial performance from adolescence to older age
Associations between APOE ε4 genotypes and echocardiographic and cardiac MRI data in older age. As APOE ε4 carriers had a higher myocardial contraction fraction, the mechanistic pathways were explored by adjusting the models for mediators (body mass index, cardiovascular disease, diabetes, high cholesterol, and hypertension). EF, ejection fraction; IVS, interventricular septal thickness; LVmass, left ventricular mass, LVPW left ventricular posterior wall thickness; MCF myocardial contraction fraction; PDSR, longitudinal/radial peak diastolic strain rate