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Table 1 , baseline characteristics of patients at the time of surgery

From: Sex-based association between high-density lipoprotein cholesterol and adverse outcomes after coronary artery bypass grafting

Variables

Total (n = 17,772)

Low HDL-C (n = 13,321)

Desirable HDL-C (n = 4,451)

P value

Mean, mg/dL

36.8 ± 6.1

32.9 ± 5.6

48.7 ± 7.7

< 0.001

Age, years

67.2 ± 9.7

66.7 ± 9.7

68.8 ± 9.5

< 0.001

Female sex

4674 (26.3%)

3968 (29.8%)

706 (15.9%)

< 0.001

Diabetes mellitus

7063 (39.8%)

5680 (42.7%)

1383 (31.1%)

< 0.001

Hypertension

9515 (53.5%)

7320 (55.0%)

2195 (49.3%)

< 0.001

Current smoking

3155 (17.8%)

2375 (17.9%)

780 (17.6%)

0.661

Opium use

2894 (16.4%)

2101 (15.9%)

793 (17.9%)

0.001

FHpCVD

6501 (36.6%)

4911 (36.9%)

1590 (35.7%)

0.170

BMI, kg/m2

27.2 ± 4.2

27.5 ± 4.2

26.4 ± 4.0

< 0.001

Previous MI

5965 (33.6%)

4495 (33.7%)

1470 (33%)

0.385

Previous HF

490 (2.8%)

378 (2.9%)

112 (2.6%)

0.254

CKD

362 (2%)

297 (2.2%)

65 (1.5%)

0.002

COPD

626 (3.5%)

461 (3.5%)

165 (3.7%)

0.446

Previous CVA

1177 (6.7%)

882 (6.7%)

295 (6.7%)

0.984

PAD

323 (1.8%)

238 (1.8%)

85 (1.9%)

0.596

Previous CABG

88 (0.5%)

62 (0.5%)

26 (0.6%)

0.329

Previous PCI

1337 (7.5%)

997 (7.5%)

340 (7.6%)

0.735

LDL-C, mg/dL

96.4 ± 37.4

94.4 ± 36.6

102.5 ± 39.2

< 0.001

Triglycerides, mg/dL

132 (98–180)

140 (105–190)

110 (82–148)

< 0.001

EF, %

50 (40–55)

48 (40–55)

50 (40–55)

< 0.001

Number of grafts

   

0.446

1

338 (1.9%)

261 (2%)

77 (1.7%)

2

1995 (11.2%)

1486 (11.2%)

509 (11.4%)

3

6805 (38.3%)

5141 (38.6%)

1664 (37.4%)

4

7041 (39.6%)

5254 (39.5%)

1787 (40.2%)

5+

1581 (8.9%)

1169 (8.8%)

412 (9.3%)

OPCAB

1685 (9.6%)

1303 (9.9%)

382 (8.7%)

0.018

ACEi or ARB

11,896 (69.1%)

8970 (69.3%)

2926 (68.2%)

0.179

Statin

15,600 (89.7%)

11,719 (89.7%)

3881 (89.7%)

0.910

Aspirin

12,413 (72.1%)

9319 (72%)

3094 (72.2%)

0.856

Beta Blockers

14,354 (82.2%)

10,802 (82.4%)

3552 (81.7%)

0.335

  1. HDL-C, high density lipoprotein cholesterol; FHpCVD, family history of cardiovascular disease; BMI, body mass index; MI, myocardial infarction; HF, heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular accident; PAD, peripheral arterial disease; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; LDL-C, low density lipoprotein cholesterol; EF, ejection fraction; OPCAB, off-pump coronary artery bypass; ACEi, Angiotensin-converting-enzyme inhibitors; ARB, Angiotensin receptor blockers
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BMC Cardiovascular Disorders

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