Table 9 Survival analysis for 30-day HF rehospitalization using continuous covariates
30-day heart failure rehospitalization | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Factor | Univariate analysis | Multivariate analysis | ||||||||
Cause-specific hazards | Schoenfeld residuals | Subdistribution hazards | Cause-specific hazards | Schoenfeld residuals | Subdistribution hazards | |||||
HR (95%CI) | p-value | p-value | HR (95%CI) | p-value | HR (95%CI) | p-value | p-value | HR (95%CI) | p-value | |
Admission | ||||||||||
 Total orthoedema score | 0.9 (0.53–1.53) | 0.69 | 0.77 | 0.86 (0.58–1.29) | 0.59 |  |  |  |  |  |
 Log NT-proBNP (pg/mL) | 0.9 (0.66–1.21) | 0.48 | 0.79 | 0.87 (0.68–1.12) | 0.37 | 0.9 (0.60–1.36) | 0.63 | 0.78 | 0.89 (0.62–1.29) | 0.54 |
 Log hsTnT (pg/mL) | 0.77 (0.5–1.19) | 0.19 | 0.53 | 0.75 (0.5–1.12) | 0.14 | 0.81 (0.48–1.37) | 0.40 | 0.60 | 0.79 (0.48–1.29) | 0.35 |
 Log GDF-15 (pg/mL) | 1.1 (0.62–1.94) | 0.75 | 0.90 | 1.03 (0.71–1.48) | 0.93 | 1.28 (0.69–2.36) | 0.43 | 0.91 | 1.24 (0.76–2.04) | 0.39 |
Discharge | ||||||||||
 Total orthoedema score | 1.71 (0.98–2.99) | 0.08 | 0.65 | 1.71 (0.99–2.94) | 0.08 |  |  |  |  |  |
 Log NT-proBNP (pg/mL) | 1.14 (0.87–1.5) | 0.33 | 0.92 | 1.14 (0.93–1.4) | 0.33 | 1.23 (0.86–1.76) | 0.25 | 0.95 | 1.23 (0.90–1.69) | 0.20 |
 Log hsTnT (pg/mL) | 0.92 (0.6–1.41) | 0.69 | 0.58 | 0.92 (0.63–1.35) | 0.69 | 0.51 (0.25–1.04) | 0.03 | 0.36 | 0.51 (0.21–1.24) | 0.14 |
 Log GDF-15 (pg/mL) | 1.92 (1.01–3.65) | 0.04 | 0.80 | 1.92 (1.18–3.13) | 0.04 | 2.45 (1.17–5.13) | 0.02 | 0.91 | 2.43 (1.26–4.71) | < 0.01 |
 Diff Log NT-proBNP (pg/mL) | 0.55 (0.37–0.8) | < 0.01 | 0.87 | 0.55 (0.36–0.84) | 0.01 | 0.66 (0.44–1.00) | 0.05 | 0.91 | 0.66 (0.42–1.03) | 0.07 |
 Diff Log hsTnT (pg/mL) | 0.5 (0.22–1.14) | 0.12 | 0.01 | 0.5 (0.14–1.76) | 0.13 | 0.92 (0.45–1.88) | 0.81 | 0.16 | 0.92 (0.41–2.03) | 0.83 |
 Diff Log GDF-15 (pg/mL) | 0.17 (0.06–0.46) | < 0.01 | 0.99 | 0.17 (0.08–0.36) | < 0.01 | 0.25 (0.08–0.78) | 0.02 | 0.97 | 0.25 (0.10–0.65) | < 0.01 |