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Table 8 Survival analysis for 30-day all-cause mortality using categorical covariates

From: GDF-15: a novel biomarker of heart failure predicts short-term and long-term heart-failure rehospitalization and short-term mortality in patients with acute heart failure syndrome

30-day all-cause mortality

Factor

Threshold

Univariate analysis

Multivariate analysis

Cox proportional hazards

Log-Rank

Schoenfeld residuals

Cox proportional hazards

Schoenfeld residuals

HR (95%CI)

p-value

p-value

p-value

HR (95%CI)

p-value

p-value

Admission

 Grading orthoedema score

  

0.12

0.12

0.85

   

  No congestion

0

1.00 (reference)

      

  Low grade

1–2

13310950 (0-Inf)

1.00

1.00

    

  High grade

3–4

83623350 (0-Inf)

1.00

1.00

    

 NT-proBNP

> 4577.00 pg/mL

3.31 (0.37–29.6)

0.24

0.26

0.03

1.02 (0.06–16.3)

0.99

0.03

 hsTnT

> 38.53 pg/mL

3.7 (0.41–33.1)

0.19

0.21

0.58

2.68 (0.17–43.1)

0.49

0.58

 GDF-15

> 6221.50 pg/mL

531526700 (0-Inf)

0.01

0.03

1.00

460,058,863 (0.00-Inf)

1.00

1.00

Discharge

 Grading orthoedema score

≥ 1 (congestion present)

0 (0-Inf)

0.52

0.63

    

 NT-proBNP

> 4577.00 pg/mL

0 (0-Inf)

0.29

0.39

 

0.00 (0.00-Inf)

1.00

0.79

 hsTnT

> 38.53 pg/mL

690142100 (0-Inf)

0.22

0.28

 

16,794,936,545 (0.00-Inf)

1.00

0.73

 GDF-15

> 6221.50 pg/mL

736669700 (0-Inf)

0.21

0.27

 

3,593,508,140 (0.00-Inf)

1.00

0.77

 NT-proBNP admission:discharge

> 1.0992464

611477,700 (0-Inf)

0.23

0.31

 

1,679,461,779 (0.00-Inf)

1.00

0.82

 hsTnT admission:discharge

> 1.13408464

0 (0-Inf)

0.24

0.32

 

0.00 (0.00-Inf)

1.00

0.92

 GDF-15 admission:discharge

> 1.8079528

0 (0-Inf)

0.24

0.32

 

0.00 (0.00-Inf)

1.00

0.57