Table 3 Orthoedemascore and continuous biomarker covariates in patients with 30-day HF rehospitalization
30-day heart failure rehospitalization | ||||
|---|---|---|---|---|
Admission | ||||
Factors | Total | Non rehospitalization | Rehospitalization | P value |
|  | (N = 84) | (N = 71) | (N = 13) |  |
Total orthoedema score | Â | Â | Â | 0.64 |
    mean ± S.D | 2.29 ± 0.98 | 2.31 ± 1.01 | 2.15 ± 0.80 |  |
    median (IQR) | 2.00 (2.00–3.00) | 2.00 (2.00–3.00) | 2.00 (2.00–3.00) |  |
NT-proBNP (pg/mL) | Â | Â | Â | 0.30 |
    mean ± S.D | 9,901 ± 10,132 | 10,505 ± 10,477 | 6,601 ± 7,470 |  |
    median (IQR) | 5,529 (2,260–13,918) | 5,628 (2,283–15,889) | 3,513 (2,272–8,896) |  |
hsTnT (pg/mL) | Â | Â | Â | 0.11 |
    mean ± S.D | 217 ± 852 | 245 ± 923 | 67 ± 125 |  |
    median (IQR) | 40 (27–94) | 44 (27–100) | 32 (22–34) |  |
Factors | Total | Non rehospitalization | Rehospitalization | P value |
|  | (N = 83) | (N = 71) | (N = 12) |  |
GDF-15 (pg/mL) | Â | Â | Â | 0.91 |
    mean ± S.D | 9,119 ± 6,011 | 9,318 ± 6,366 | 7,942 ± 3,111 |  |
    median (IQR) | 6,879 (4,428–12,387) | 6,855 (4,132–13,290) | 7,330 (5,344–11,013) |  |
Discharge | ||||
Factors | Total | Non rehospitalization | Rehospitalization | P value |
|  | (N = 84) | (N = 71) | (N = 13) |  |
Total orthoedema score | Â | Â | Â | 0.053 |
    mean ± S.D | 0.38 ± 0.79 | 0.30 ± 0.72 | 0.77 ± 1.01 |  |
    median (IQR) | 0.00 (0.00–0.00) | 0.00 (0.00–0.00) | 0.00 (0.00–2.00) |  |
Factors | Total | Non rehospitalization | Rehospitalization | P value |
|  | (N = 71) | (N = 60) | (N = 11) |  |
Log NT-proBNP (pg/mL) | Â | Â | Â | 0.28 |
    mean ± S.D | 7,091 ± 11,041 | 7,298 ± 11,870 | 5,961 ± 4,514 |  |
    median (IQR) | 3,306 (690–7,863) | 2,862 (671–7,447) | 4,739 (3,140–9,235) |  |
hsTnT (pg/mL) | Â | Â | Â | 0.64 |
    mean ± S.D | 92 ± 165 | 97 ± 173 | 67 ± 110 |  |
    median (IQR) | 37 (22–64) | 38 (20–69) | 28 (26–46) |  |
GDF-15 (pg/mL) | Â | Â | Â | 0.028 |
    mean ± S.D | 7,107 ± 4,788 | 6,737 ± 4,893 | 9,128 ± 3,728 |  |
    median (IQR) | 5,659 (3,662–8,735) | 5,376 (3,370–8,102) | 8,539 (6,898–10,911) |  |
NT-proBNP admission:discharge | Â | Â | Â | 0.002 |
    mean ± S.D | 2.88 ± 3.84 | 3.20 ± 4.09 | 1.16 ± 0.92 |  |
    median (IQR) | 1.81 (1.08–3.04) | 1.96 (1.37–3.06) | 0.69 (0.61–1.39) |  |
hsTnT admission:discharge | Â | Â | Â | 0.19 |
    mean ± S.D | 1.48 ± 1.43 | 1.46 ± 1.35 | 1.56 ± 1.89 |  |
    median (IQR) | 1.13 (0.96–1.34) | 1.14 (1.00–1.35) | 0.95 (0.85–1.18) |  |
Factors | Total | Non rehospitalization | Rehospitalization | P value |
|  | (N = 70) | (N = 60) | (N = 10) |  |
GDF-15 admission:discharge | Â | Â | Â | 0.018 |
    mean ± S.D | 1.39 ± 0.93 | 1.47 ± 0.97 | 0.89 ± 0.38 |  |
    median (IQR) | 1.10 (0.96–1.63) | 1.20 (1.00–1.66) | 0.95 (0.70–1.09) |  |