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Table 2 Baseline characteristics of patients diagnosed with acute heart failure syndrome with 30-day HF rehospitalization

From: GDF-15: a novel biomarker of heart failure predicts short-term and long-term heart-failure rehospitalization and short-term mortality in patients with acute heart failure syndrome

Factors

Total

(N = 84)

Non rehospitalization

(N = 71)

Rehospitalization

(N = 13)

P value

Age (mean ± S.D.)

69 ± 14 (19–97)

70 ± 13 (34–97)

66 ± 20 (19–92)

0.535

Male gender

40 (47.6%)

36 (50.7%)

4 (30.8%)

0.186

Ethnicity (Thai)

83 (98.8%)

70 (98.6%)

13 (100%)

1.000

Past History

 Hx of HF

60 (73.2%)

48 (69.6%)

12 (92.3%)

0.169

 LVEF

   

0.310

 No previous echo

11 (16.9%)

11 (20.4%)

0

 

 pEF (> = 50%)

34 (52.3%)

28 (51.9%)

6 (54.5%)

 

 mrEF (40–49%)

5 (7.7%)

4 (7.4%)

1 (9.1%)

 

 rEF (< 40%)

15 (23.1%)

11 (20.4%)

4 (36.4%)

 

 Hx of HF hospitalization

44 (67.7%)

36 (64.3%)

8 (88.9%)

0.251

 Diabetes mellitus

50 (59.5%)

44 (62%)

6 (46.2%)

0.285

 Ischemic heart disease

32 (38.1%)

26 (36.6%)

6 (46.2%)

0.546

 Atrial fibrillation

27 (32.1%)

23 (32.4%)

4 (30.8%)

1.000

 Hypertension

63 (75%)

57 (80.3%)

6 (46.2%)

0.015

 Dyslipidemia

47 (56%)

43 (60.6%)

4 (30.8%)

0.047

 CKD at least stage III

33 (39.3%)

30 (42.2%)

3 (23.1%)

0.362

Treatment (Prior to admission) (mean ± S.D.)/median (IQR)

 Furosemide

51 (60.7%)

40 (56.3%)

11 (84.6%)

0.055

 Furosemide (mg/day)

171.57 ± 272.78

40 (20–240)

145 ± 237.17

40 (20–120)

268.18 ± 373.60

60 (40–250)

0.327

 Betablocker (BB)

49 (58.3%)

41 (57.7%)

8 (61.5%)

0.799

 ACEI

11 (13.1%)

10 (14.1%)

1 (7.7%)

1.000

 ARB

15 (17.9%)

13 (18.3%)

2 (15.4%)

1.000

 Spironolactone

7 (8.3%)

5 (7%)

2 (15.4%)

0.295

 Digoxin

5 (6%)

3 (4.2%)

2 (15.4%)

0.169

Treatment at discharge (mean ± S.D.)/median (IQR)

 Furosemide

66 (78.6%)

54 (76.1%)

12 (92.3%)

0.281

 Furosemide (mg/day)

190.92 ± 276.18

80 (40–160)

174.34 ± 269.93

80 (20–160)

264.17 ± 303.6

120 (40–500)

0.210

 HCTZ

2 (2.4%)

1 (1.4%)

1 (7.7%)

0.287

 Tolvaptan

1 (1.2%)

0

1 (7.7%)

0.155

 Betablocker

50 (59.5%)

42 (59.2%)

8 (61.5%)

0.872

 ACEI

9 (10.7%)

8 (11.3%)

1 (7.7%)

1.000

 ARB

8 (9.5%)

8 (11.3%)

0

0.347

 Spironolactone

4 (4.8%)

2 (2.8%)

2 (15.4%)

0.111

 Digoxin

5 (6%)

4 (5.6%)

1 (7.7%)

0.578