Early detection of left atrial and bi-ventricular myocardial strain abnormalities by MRI feature tracking in normotensive or hypertensive T2DM patients with preserved LV function

Shao, Guozhu; Cao, Yukun; Cui, Yue; Han, Xiaoyu; Liu, Jia; Li, Yumin; Li, Na; Liu, Tong; Yu, Jie; Shi, Heshui

doi:10.1186/s12872-020-01469-2

Table 4 Univariate regression analysis for LAGLS, LAGCS, LAGRS and RVGLS in normotensive or hypertensive T2DM patients

From: Early detection of left atrial and bi-ventricular myocardial strain abnormalities by MRI feature tracking in normotensive or hypertensive T2DM patients with preserved LV function

	LAGLS (%)		LAGCS (%)		LAGRS (%)		RVGLS(%)
Variable	R value	P value	R value	P value	R value	P value	R value	P value
Age (years)	−0.019	0.897	−0.047	0.745	0.219	0.126	−0.094	0.516
sex	0.003	0.981	− 0.151	0.294	0.205	0.153	0.009	0.953
BMI (kg/m²)	−0.086	0.553	−0.154	0.285	0.272	0.056	0.033	0.821
SBP (mmHg)	0.134	0.353	0.103	0.475	−0.035	0.809	0.221	0.123
DBP (mmHg)	0.181	0.209	0.219	0.127	−0.155	0.282	−0.001	0.997
Diabetes duration (y)	0.056	0.697	0.025	0.861	0.136	0.347	−0.214	0.136
BUN (mmol/L)	−0.084	0.562	−0.058	0.687	0.169	0.241	−0.276	0.052
Creatinine (μmol/L)	−0.016	0.914	−0.107	0.460	0.243	0.090	−0.093	0.519
Total cholesterol (mmol/L)	0.030	0.835	−0.029	0.842	0.056	0.699	−0.251	0.079
Triglycerides (mmol/L)	0.095	0.512	0.059	0.682	−0.090	0.534	−0.084	0.564
HDL-C (mmol/L)	−0.020	0.891	−0.252	0.078	0.162	0.261	0.013	0.929
LDL-C (mmol/L)	0.029	0.843	0.021	0.887	0.059	0.684	−0.222	0.122
FPG (mmol/L)	−0.037	0.801	0.127	0.378	−0.087	0.549	−0.134	0.354
Hemoglobin A1C (%)	−0.288^*	0.042	0.070	0.629	0.037	0.796	0.050	0.729
MA	−0.198	0.169	−0.344^*	0.014	0.220	0.125	−0.134	0.354
Insulin	−0.156	0.279	−0.168	0.245	0.123	0.396	−0.120	0.407
Metformin	−0.149	0.301	−0.111	0.442	0.152	0.293	−0.220	0.125
Sulphonylurea	0.034	0.813	0.106	0.465	0.052	0.722	0.003	0.981
Statin	0.048	0.738	0.165	0.252	−0.110	0.446	−0.117	0.418
Aspirin	0.052	0.721	0.222	0.120	−0.054	0.711	−0.021	0.885
ACEI	0.098	0.497	0.065	0.653	0.099	0.493	−0.099	0.493
Diuretics	0.686^**	0.000	0.451^**	0.001	−0.459^**	0.001	0.260	0.068
Calcium channel blockers	0.041	0.780	−0.017	0.907	0.122	0.399	−0.076	0.602
β-blockers	−0.251	0.079	−0.050	0.728	0.277	0.051	0.107	0.462

LAGLS, left atrial global longitudinal strain; LAGCS, left atrial global circumferential strain; LAGRS, left atrial global radial strain; RVGLS, right ventricular global longitudinal strain
BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; BUN, blood urea nitrogen; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting plasma glucose; MA, microalbuminuria; ACEI, angiotensin-converting enzyme inhibitor

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ISSN: 1471-2261

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