The influence of dehydration on the prognosis of acute ischemic stroke for patients treated with tissue plasminogen activator

Table 3 Multivariate analysis of variables associated with prognosis as assessed by the mRS

Variable	OR (95% CI)	p-value
Multivariate analysis after the forward stepwise method
Bun/Cr
< 15--Non-dehydration	ref
≥ 15--Dehydration	0.46(0.27–0.79)	0.004^*
PL	1.003(0.9996–1.01)	0.079
SPG	1.28 × 10⁻³¹ (4.88 × 10⁻⁴⁹ - 3.38 × 10⁻¹⁴)	0.001^*
Stratified by TOAST
For Cardioembolism
Bun/Cr
< 15--Non-dehydration	ref
≥ 15--Dehydration	0.96(0.37–2.46)	0.929
PL	0.999(0.99–1.01)	0.766
SPG	7.71 × 10⁻²⁵(8.76 × 10⁻⁵² - 677.77)	0.079
For Lacune
Bun/Cr
< 15--Non-dehydration	ref
≥ 15--Dehydration	0.24(0.06–1.01)	0.052
PL	1.02(1.004–1.04)	0.019^*
SPG	9.75 × 10⁻⁷⁸(5.11 × 10⁻¹⁶³ - 1.86 × 10⁸)	0.077
For Large-artery atherosclerosis
Bun/Cr
< 15--Non-dehydration	ref
≥ 15--Dehydration	0.65(0.20–2.08)	0.472
PL	1.004(0.997–1.01)	0.261
SPG	1.38 × 10⁻²⁵ (9.05 × 10⁻⁶² - 2.10 × 10¹¹)	0.178

Abbreviations: BI Barthel Index, BUN blood urea nitrogen, Cr creatinine, mRS modified Rankin Scale. For all other abbreviations see the List of Abbreviations
* p < 0.05, significantly associated with prognosis

ISSN: 1471-2261