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Table 2 Arterial blood gas, hematocrit, and hemodynamic variables before and after ECLS

From: Investigation of the pathophysiology of cardiopulmonary bypass using rodent extracorporeal life support model

 

Baseline

30 min

60 min

90 min

120 min

pHa

 NC + ECLS

7.54±0.01

7.44±0.01

7.38±0.01

7.40±0.01

7.42±0.01

 CA + ECLS

7.55±0.01

7.43±0.02

7.33±0.02

7.33±0.02

7.32±0.02*

PaO2 (mmHg)

 NC + ECLS

92±2

120±3

99±1

89±1

83±1

 CA + ECLS

90±1

114±3

102±3

87±4

84±4

PaCO2 (mmHg)

 NC + ECLS

28.3±0.6

18.5±0.3

21.8±0.4

23.6±0.4

24.5±0.5

 CA + ECLS

25.9±0.7

19.0±0.8

21.9±1.3

28.6±1.8

27.5±1.9

Base excess (mmol L-1)

 NC + ECLS

1.5±0.2

−11.4±0.3

−12.3±0.3

−10.4±0.3

−8.5±0.3

 CA + ECLS

0±0.2

−11.5±0.7

−13.8±1.2

−10.1±1.3

-10.7±1.5

Hematocrit (%)

 NC + ECLS

40±0

19±0

21±0

23±0

24±0

 CA + ECLS

40±0

17±0

21±0

23±1

25±0

Heart rate (beats min−1)

 NC + ECLS

381.8±3.7

348.5±3.8

398.6±2.7

413.4±2.4

429.6±2.2

 CA + ECLS

384.9±4.4

367.1±5.1

417.2±3.7

430.6±4.8

419.3±8.9

Mean arterial pressure (mmHg)

 NC + ECLS

121.1±0.9

41.0±0.8

58.9±1.2

72.8±1.2

75.1±1.0

 CA + ECLS

113.3±1.3

35.5±1.9

55.6±2.5

73.1±3.0

76.4±3.3

  1. Variables are presented as mean ± SEM. The data depended on the number of surviving rats at each time point. CA + ECLS: asphyxial cardiac arrest rats rescued by ECLS; ECLS: extracorporeal life support; NC + ECLS: normal rats treated with ECLS.
  2. *: P < 0.05 when the CA + ECLS group was compared with the NC + ECLS group at the same time point