Bleeding events associated with a low dose (110 mg) versus a high dose (150 mg) of dabigatran in patients treated for atrial fibrillation: a systematic review and meta-analysis

Table 2 General features of the studies which were included in this meta-analysis

Studies	Type of study	Patients’ enrollment	No of patients treated with 110 mg dabigatran (n)	No of patients treated with 150 mg dabigatran (n)	NVAF
Connolly2013 [22]	RCT	2008–2012	2914	2937	+
Eikelboon2013 [23]	RCT	2005–2009	6015	6076	+
Larsen2013 [24]	Observational	2011–2012	2326	1760	+
Maura2015 [25]	Observational	2011–2012	1198	490	+
Nishtala2016 [26]	Observational	2011–2012	3395	2153	+
Total no of patients (n)			15,848	13,416

Abbreviations: RCT randomized controlled trials, AF atrial fibrillation, NVAF non-valvular atrial fibrillation

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