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Table 1 Patients’ characteristics

From: Violation of prophylactic vancomycin administration timing is a potential risk factor for rate of surgical site infections in cardiac surgery patients: a prospective cohort study

 

Low risk (n = 402)

High risk (n = 339)

Without protocol violation

With protocol violation

P

Without protocol violation

With protocol violation

P

n

236

166

 

200

139

 

Age, median (range)

70 (25–86)

70 (34–84)

0.51

71 (37–88)

71 (44–88)

0.50

Male gender, n (%)

149 (63)

100 (60.2)

0.63

124 (62)

74 (53.2)

0.13

BMI, kg/m2, median (range)

26 (18–40)

26 (18–39)

0.81

28 (17–43)

28 (17–41)

0.84

Diabetes, n (%)

46 (19)a

27 (16.3)a

0.41

50 (25)b

45 (32.4)b

0.17

COPD, n (%)

0

0

─

24 (12)

13 (9.3)

0.55

Hypertension, n (%)

151 (64)

108 (65.1)

0.91

132 (66)

99 (71.2)

0.37

Smoke, n (%)

28 (12)

30 (18.1)

0.11

52 (26)

48 (34.5)

0.12

Surgical time, min, median (range)

249 (119–593)

255 (132–495)

0.49

247 (140–442)

243 (152–430)

0.60

Surgical procedure, n (%)

  

0.08

  

0.11

 CABG

72 (30.5)

58 (34.9)

 

70 (35)

53 (38.1)

 

 Valve

113 (47.9)

59 (35.5)

52 (26)

24 (17.3)

 CABG + Valve

34 (14.4)

30 (18.1)

24 (12)

12 (8.6)

 Otherc

17 (7.2)

19 (11.5)

54 (27)

50 (36)

Off-pump CABG, n (%)

21 (8.9)

8 (4.8)

0.17

11 (5.5)

9 (6.5)

0.89

Left IMA, n (%)

53 (22.4)

40 (24.1)

0.79

44 (22)

33 (23.7)

0.81

Both IMA, n (%)

17 (7.2)

8 (4.8)

0.44

13 (6.5)

9 (6.5)

>0.99

EuroSCORE additive, median (range)

5 (1–6)

5 (1–6)

0.80

8 (1–16)

8 (1–14)

0.72

EuroSCORE logistic, median (range)

4.8 (1–7.74)

4.6 (1–7.21)

0.41

9.7 (1–44.45)

9.9 (1–61.86)

0.37

Mechanical ventilation, h, median (range)

7 (2–912)

8 (6–415)

0.31

9 (7–816)

9 (8–711)

0.49

ICU stay, d, median (range)

1 (1–24)

1 (1–38)

0.52

1 (1–33)

1 (1–45)

0.30

RBC transfusions, n, median (range)

2 (0–9)

2 (0–6)

0.71

3 (0–11)

2 (0–10)

0.61

  1. BMI body mass index, COPD chronic obstructive pulmonary disease, CABG coronary artery bypass grafting, IMA internal mammary artery, EuroSCORE European System for Cardiac Operative Risk Evaluation, h hours, ICU intensive care unit, d days, RBC red blood cell
  2. aNon-insulin-dependent diabetes
  3. bInsulin-dependent diabetes
  4. cAortic, atrial or ventricular septal defect repair, and congenital surgery