Table 1 Demographic and clinical data for the study population
Parameter | Controls | Diameter of ascending aorta | p | |||
|---|---|---|---|---|---|---|
Group 1 (≤45 mm) | Group 2 (>45 mm) | Controls vs. group 1 | Controls vs. group 2 | Group 1 vs. group 2 | ||
Age (years) | 58.2 ± 7.1 | 52.9 ± 13.8 | 60.1 ± 12.2 | NS | NS | NS |
Sex (F/M) (%) | 43.3/56.7 | 18.8/81.2 | 25.0/75.0 | NS | NS | NS |
Body surface area (m2) | 1.91 ± 0.2 | 2.01 ± 0.2 | 2.0 ± 0.2 | NS | NS | NS |
Arterial hypertension (%) | 65.2 | 60.0 | 89.3 | NS | 0.02 | 0.02 |
Blood pressure (mmHg) | ||||||
Systolic | 134.6 ± 13.7 | 138.8 ± 17.7 | 145.8 ± 23.5 | NS | 0.01 | NS |
Diastolic | 84.1 ± 9.6 | 73.4 ± 13.0 | 78.8 ± 11.8 | 0.003 | 0.03 | NS |
Antihypertensive Rx (%) | ||||||
β-Blockers | 25.5 | 85.7 | 77.8 | <0.05 | 0.001 | NS |
ACE-I | 22.0 | 64.3 | 55.6 | <0.05 | 0.002 | NS |
ARB | 17.6 | 7.7 | 18.5 | NS | NS | NS |
Smokers (%) | 28.8 | 0 | 7.4 | <0.05 | 0.02 | NS |
Aortic valve pathology (%) | ||||||
Aortic valve insufficiency | 0 | 50.0 | 53.8 | <0.001 | <0.001 | NS |
Stenosis | 0 | 6.2 | 15.4 | NS | 0.002 | NS |
Bicuspid | 0 | 62.5 | 30.4 | 0.001 | 0.001 | 0.04 |