Control (n = 6) | Sham (n = 6) | PADN (n = 7) | |
---|---|---|---|
Heart beats/min | |||
Week 0 Week 8 Week 14 | 147.71 ± 25.09 138.57 ± 22.87 134.43 ± 37.95 | 160.00 ± 17.06 157.70 ± 22.26 159.60 ± 23.81 | 158.67 ± 13.37 165.89 ± 10.75 159.67 ± 10.14 |
PVR, Wood units | |||
Week 0 Week 8 Week 14 | 3.08 ± 0.50 2.99 ± 0.46 2.57 ± 0.54 | 2.68 ± 0.52 6.47 ± 1.61* 7.72 ± 2.69* | 2.70 ± 0.78 5.18 ± 0.75**,*** 4.87 ± 1.13**,**** |
mPAP, mmHg | |||
Week 0 Week 8 Week 14 | 15.29 ± 2.24 16.87 ± 1.66 17.27 ± 2.77 | 14.40 ± 3.57 28.64 ± 4.22* 33.72 ± 5.76* | 14.56 ± 3.00 27.71 ± 1.72**,*** 25.94 ± 3.67**,**** |
PADP, mmHg | |||
Week 0 Week 8 Week 14 | 9.41 ± 2.62 11.02 ± 2.24 9.93 ± 2.71 | 8.70 ± 3.62 20.84 ± 4.72* 24.90 ± 6.10* | 9.56 ± 3.21 19.10 ± 2.37** 17.79 ± 3.58**,**** |
PASP, mmHg | |||
Week 0 Week 8 Week 14 | 27.96 ± 2.24 29.98 ± 2.29 32.24 ± 3.02 | 27.30 ± 3.80 45.22 ± 5.48* 52.14 ± 6.63* | 27.11 ± 4.70 46.40 ± 3.93** 43.70 ± 4.58**,**** |
mRVP, mmHg | |||
Week 0 Week 8 Week 14 | 10.49 ± 1.54 11.10 ± 1.68 11.93 ± 1.48 | 9.80 ± 3.19 14.96 ± 2.61* 18.52 ± 2.07* | 10.11 ± 2.20 14.89 ± 1.83** 15.25 ± 2.45***,**** |
RVSP, mmHg | |||
Week 0 Week 8 Week 14 | 32.01 ± 3.69 33.38 ± 3.35 36.06 ± 4.30 | 32.40 ± 7.03 49.06 ± 6.76* 55.84 ± 5.75* | 31.89 ± 6.45 50.00 ± 4.18** 46.40 ± 6.77**,**** |
PAOP, mmHg | |||
Week 0 Week 8 Week 14 | 4.57 ± 1.40 5.29 ± 2.14 6.00 ± 1.63 | 4.70 ± 1.64 6.20 ± 2.25 4.90 ± 2.02 | 4.89 ± 1.69 5.67 ± 2.83 5.89 ± 2.09 |
CO, L/min | |||
Week 0 Week 8 Week 14 | 3.39 ± 0.35 3.86 ± 0.84 4.40 ± 1.24 | 3.61 ± 0.84 3.55 ± 0.66 4.02 ± 1.10 | 3.69 ± 0.85 4.22 ± 0.77 4.18 ± 0.63 |