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Table 4 Cox regression analysis of the associations between 180-day cumulative mortality and the clinical findings

From: The serum heart-type fatty acid-binding protein (HFABP) levels can be used to detect the presence of acute kidney injury on admission in patients admitted to the non-surgical intensive care unit

 

Univariate analysis

Multivariate analysis

180-days mortality

HR

95 % CI

p value

HR

95 % CI

p value

H-FABP level and AKI status

 H-FABP≦15.6 and no-AKI

1.000

  

1.000

  

 H-FABP≦15.6 and AKI

4.128

1.432–11.898

0.009

2.676

0.920–7.783

0.071

 H-FABP≧15.7 and no-AKI

8.070

3.592–18.131

<0.001

9.268

3.835–22.396

<0.001

 H-FABP≧15.7 and AKI

14.037

6.556–30.054

<0.001

11.593

5.154–26.078

<0.001

Adjusting factors

 Chronic kiedney disease

0.887

0.560–1.405

0.609

   

 Age (≧69 years old)

1.036

0.659–1.629

0.879

   

 MBP (≧99 mmHg)

0.205

0.114–0.366

<0.001

0.239

0.130–0.441

<0.001

 LVEF (≧51 %)

0.652

0.396–1.074

0.093

   

 Hemoglobin (≧13.5 g/dl)

0.567

0.352–0.912

0.019

0.990

0.603–1.624

0.968

 Hs-TropT (≧0.064 ng/ml)

2.429

1.478–3.994

<0.001

0.818

0.469 –1.424

0.477

 Nt-ProBNP (≧930 pg/ml)

1.598

1.001–2.552

0.050

   
  1. HR hazard ratio, CI confidence interval, H-FABP heart-type fatty acid binding, MBP mean blood pressure, LVEF left ventricular ejection fraction measured on echocardiography, Hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide