Table 1 Patient characteristics categorized by ventricular conduction block patterns
All patients (n = 1119) | LBBB (n = 221) | RBBB (n = 82) | IVCD (n = 67) | Narrow QRS (n = 749) | P value | |
|---|---|---|---|---|---|---|
Age (years) | 51.1 ± 14.7 | 57.2 ± 12.0 | 53.1 ± 14.7 | 52.3 ± 14.5 | 48.9 ± 14.9 | <0.001 a |
Female gender, n (%) | 298(26.6) | 89(40.3) | 16(19.5) | 15(22.4) | 178(23.8) | <0.001 |
History | ||||||
Disease duration (years) | 2(0.5–6) | 4(1–9) | 4(1–8) | 3(1.5–6) | 2(0.35–5) | 0.001 |
Essential hypertension, n (%) | 294(26.3) | 73(33.0) | 15(18.3) | 15(22.4) | 191(25.5) | 0.034 |
Diabetes mellitus, n (%) | 160(14.3) | 24(10.9) | 15(18.3) | 6(9.0) | 115(15.4) | 0.142 |
Atrial fibrillation, n (%) | 257(23.0) | 29(13.1) | 20(24.4) | 11(16.4) | 197(26.3) | <0.001 |
Smoker, n (%) | 517(46.2) | 93(42.1) | 33(40.2) | 31(46.3) | 360(48.1) | 0.293 |
Drinker, n (%) | 363(32.4) | 59(26.7) | 28(34.1) | 22(32.8) | 254(33.9) | 0.243 |
NYHA class III and IVc, n (%) | 817(73.0) | 162(73.3) | 60(73.2) | 54(80.6) | 541(72.2) | 0.532 |
Admission vital signs | ||||||
SBP (mm Hg) | 113.0 ± 17.7 | 114.6 ± 17.3 | 110.2 ± 18.8 | 111.7 ± 19.8 | 113.0 ± 17.4 | 0.242 |
DBP(mm Hg) | 72.5 ± 12.6 | 71.8 ± 12.4 | 71.8 ± 11.1 | 69.3 ± 12.4 | 73.0 + 12.8 | 0.099 |
Heart rate, beat/min | 80.9 ± 17.4 | 78.3 ± 15.9 | 79.6 ± 15.5 | 78.6 ± 14.4 | 82.0 ± 18.2 | 0.023 |
Laboratory values at admissionb | ||||||
TB (mmol/L) | 26.2 ± 19.6 | 24.9 ± 19.1 | 25.3 ± 16.0 | 34.8 ± 26.7 | 26.0 ± 19.3 | 0.004 |
DB (mmol/L) | 3.7(2.5–6.5) | 3.2(2.15–6.05) | 3.5(2.7–7.4) | 4.9(3.2–9.2) | 3.7(2.5–6.485) | 0.003 |
Glucose (mmol/L) | 5.62 ± 1.85 | 5.86 ± 1.94 | 5.50 ± 1.52 | 5.34 ± 1.44 | 5.59 ± 1.89 | 0.150 |
Triglyceride (mmol/L) | 1.57 ± 1.02 | 1.63 ± 0.99 | 1.58 ± 0.94 | 1.38 ± 0.70 | 1.56 ± 1.06 | 0.410 |
Total cholesterol (mmol/L) | 4.61 ± 1.13 | 4.75 ± 1.12 | 4.52 ± 0.98 | 4.39 ± 1.23 | 4.59 ± 1.14 | 0.125 |
Creatinine (μmol/L) | 92.8 ± 35.2 | 91.0 ± 26.4 | 94.9 ± 25.9 | 97.9 ± 40.7 | 92.6 ± 37.8 | 0.526 |
BUN (μmol/L) | 7.95 ± 3.97 | 7.88 ± 2.67 | 8.04 ± 2.69 | 8.89 ± 4.68 | 7.88 ± 4.32 | 0.262 |
CK-MB (IU/L) | 13.5 ± 7.76 | 13.1 ± 6.77 | 12.0 ± 6.70 | 13.7 ± 7.59 | 13.8 ± 8.14 | 0.229 |
NT- Pro- BNP (fmol/mL) | 2010.3 ± 1567.5 | 1998.0 ± 1595.8 | 2170.5 ± 1679.8 | 2358.4 ± 1638.4 | 1962.4 ± 1538.0 | 0.315 |
Electrocardiogram data | ||||||
QRS duration (ms) | 119.6 ± 30.9 | 156.0 ± 24.4 | 153.3 ± 24.9 | 137.1 ± 23.1 | 103.6 ± 18.2 | <0.001 |
QT (ms) | 405.7 ± 54.2 | 434.4 ± 50.6 | 429.1 ± 51.1 | 421.3 ± 38.7 | 393.2 ± 52.4 | <0.001 |
P (ms) | 107.5 ± 21.6 | 102.7 ± 22.6 | 107.5 ± 23.6 | 108.2 ± 25.1 | 109.3 ± 20.3 | 0.005 |
PR (ms) | 182.8 ± 32.9 | 184.9 ± 33.1 | 192.3 ± 42.0 | 193.6 ± 34.7 | 179.7 ± 30.7 | 0.001 |
Echocardiography data | ||||||
LV (mm) | 68.0 ± 9.3 | 71.4 ± 11.4 | 68.7 ± 8.3 | 70.9 ± 13.1 | 66.7 ± 8.0 | <0.001 |
LVEF (%) | 31.9 ± 8.4 | 31.0 ± 8.2 | 31.8 ± 7.3 | 30.5 ± 9.0 | 32.3 ± 8.5 | 0.142 |
RV (mm) | 23.6 ± 5.4 | 22.0 ± 5.0 | 24.1 ± 5.6 | 24.5 ± 5.5 | 24.0 ± 5.4 | <0.001 |
LA (mm) | 43.9 ± 7.7 | 43.1 ± 7.9 | 45.8 ± 8.4 | 46.6 ± 8.9 | 43.7 ± 7.5 | 0.002 |
PASP (>40 mmHg), n (%) | 203(18.1) | 35(15.8) | 24(29.3) | 15(22.4) | 129(17.2) | 0.031 |
Medicine during admission | ||||||
Diuretics, n (%) | 1059(94.6) | 205(92.8) | 76(92.7) | 63(94.0) | 715(95.5) | 0.362 |
ACEI/ARB, n (%) | 951(85.0) | 182(82.4) | 70(85.4) | 54(80.6) | 645(86.1) | 0.396 |
Beta-blockers, n (%) | 1017(90.9) | 195(88.2) | 69(84.1) | 56(83.6) | 697(93.1) | 0.002 |
Digoxin, n (%) | 903(80.7) | 168(76.0) | 66(80.5) | 59(88.1) | 610(81.4) | 0.127 |
Aspirin/anticoagulants n (%) | 721(64.4) | 131(59.3) | 52(63.4) | 34(50.7) | 504(67.3) | 0.013 |
Spironolactone, n (%) | 1019(91.1) | 191(86.4) | 73(89.0) | 57(85.1) | 698(93.2) | 0.004 |