Table 2 Secondary preventive drugs at discharge from hospital for index AMI and 12˗18 months later; patients <85 years
Secondary preventive drugs at discharge for index AMI | Secondary preventive drugs 12–18 months after index AMI | |||||
|---|---|---|---|---|---|---|
(n = 42 707) | (n = 28 767) | |||||
n (%) | Mean dose (mg) | n (%) | Mean dose (mg) | n (%) switched to another drug within same drug class in post-AMI period | n (%) changed dose of actual drug in post-AMI period | |
Statins | 38 228 (89.5) | 24 062 (83.6) | ||||
Simvastatin | 23 528 (55.1) | 37.2 | 12 478 (43.4) | 38.4 | 2571 (15.7) | 1415 (8.7) |
Atorvastatin | 17 084 (40.0) | 56.9 | 10 913 (37.9) | 52.1 | 592 (6) | 1755 (17.8) |
Rosuvastatin | 225 (0.5) | 17.7 | 367 (1.3) | 19.6 | 10 (9.6) | 13 (12.5) |
Pravastatin | 1158 (2.7) | 33.5 | 651 (2.3) | 33.5 | 120 (20.9) | 39 (6.8) |
ACEI/ARB a | 25 445 (59.6) | 16 274 (56.6) | ||||
Losartan | 3658 (8.6) | 66.6 | 2049 (7.1) | 66.5 | 153 (6.9) | 238 (10.8) |
Candersartan | 4157 (9.7) | 13.1 | 2778 (9.7) | 13.5 | 145 (5.4) | 467 (17.4) |
Valsartan | 1503 (3.5) | 124.9 | 865 (3.0) | 125.2 | 68 (7.2) | 127 (13.4) |
Irbesartan | 1530 (3.6) | 235.6 | 770 (2.7) | 237.3 | 72 (7.8) | 61 (6.6) |
Enalapril | 2951 (6.9) | 11.8 | 1657 (5.8) | 11.9 | 170 (8.9) | 324 (16.9) |
Ramipril | 11 492 (26.9) | 3.5 | 6999 (24.3) | 4.5 | 733 (8.8) | 2156 (25.8) |
Lisinopril | 1753 (4.1) | 11.3 | 949 (3.3) | 11.3 | 121 (10.3) | 207 (17.5) |
Beta-blockers | 34 986 (81.9) | 22 061 (76.7) | ||||
Metoprolol | 30 874 (72.3) | 60.6 | 18 920 (65.8) | 62.3 | 702 (3.2) | 4452 (20.3) |
Atenolol | 1381 (3.2) | 52.4 | 457 (1.6) | 51.0 | 117 (21.6) | 54 (10) |
Propranolol | 305 (0.7) | 66.2 | 82 (0.3) | 80.4 | 26 (26.3) | 6 (6.1) |
Sotalol | 358 (0.8) | 80.3 | 138 (0.5) | 75.9 | 49 (33.3) | 14 (9.5) |
Bisoprolol | 2477 (5.8) | 4.1 | 1856 (6.5) | 4.4 | 64 (4) | 310 (19.3) |
Carvedilol | 1298 (3.0) | 15.8 | 813 (2.8) | 15.6 | 73 (9.1) | 123 (15.3) |