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Table 4 Distribution of novel biochemical markers and indices of atherosclerosis among men with stable physical activity level patterns during 25 year-observation

From: Regular physical activity and cardiovascular biomarkers in prevention of atherosclerosis in men: a 25-year prospective cohort study

 

Stable physical activity level during the 25-year observation

 

Low-to-moderate (<2050 kcal/week)

High (2050-3840 kcal/week)

Very high (>3840 kcal/week)

 

n=26

n=21

n=15

Age, years

61.3 ± 9.0

58.8 ± 8.8

58.8± 8.1

hsCRP, mg/L

2.93 ± 1.1

2.20 ± 1.0*

2.82 ± 1.3

Homocysteine, μmol/L

13.55 ± 9.0

14.75 ± 4.8

14.6 ± 5.5

Oxidized-LDL, ng/mL

119.76 ± 252.3

68.35 ± 67.7*

119.48 ± 113.4

(median)

(56.80)

(13.9)

(49.50)

ICAM-1, ng/mL

498.77 ± 139.2

460.00 ± 148.8

511.2 ± 102.1

VCAM-1, ng/mL

698.55 ± 328.3

743.05 ± 272.4

617.63 ± 260.3

Interleukine-6, pg/mL

2.58 ± 5.6

1.02 ± 0.9a

2.88 ± 2.8

Leptin, ng/mL

9.10 ± 8.1

4.71 ± 3.07*

7.79 ± 5.18

Resistin, ng/mL

4.57 ± 1.8

4.99 ± 2.48

4.50 ± 1.42

Adiponectin, μmol/L

8.13 ± 2.8

8.99 ± 2.6

7.73 ± 4.4

Irisin, μmol/L

0.54 ± 0.14

0.47 ± 0.13*

0.48 ± 0.22

Coronary artery calcium

286.1 ± 361.9

10.7 ± 28.9

106.1 ± 278.3

(median)

(121.3)

(1.7)***

(6.30)

0, n

1

10**

6

Intima-media thickeness, mm

0.751 ± 0.19

0.641 ± 0.26b

0.750 ± 0.60

>0.9, n

5

0

1

Reactive hyperemia index

1.69 ± 0.4

2.00 ± 0.4

2.13 ± 0.5

<1.67, n

12

0**

3

  1. Data presented as mean ± SD unless otherwise stated; *p<0.05; ** p<0.01; ***p<0.001; a p=0.0503; b p=0.0502. Abbreviations as in Table 2