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Fig 6 | BMC Cardiovascular Disorders

Fig 6

From: Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice

Fig 6

HG increased expression of periostin via ROS/ERK/TGF-β pathway. a Resveratrol inhibited expression of TGF-β in HG-treated myofibroblasts as well as NAC. b Treatment with U0126 suppressed the elevated TGF-β induced by HG in myofibroblasts. c HG-induced increased expressions of periostin and α-SMA were suppressed by pretreatment with TGF-β neutralizing antibody. d Quantitative analysis of periostin. e Quantitative analysis of α-SMA. *p < 0.05 between two groups; **p < 0.01 between two groups

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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