Figure 2From: Inhibition of S6K1 accounts partially for the anti-inflammatory effects of the arginase inhibitor L-norvaline L-norvaline-mediated inhibition of VCAM-1, ICAM-1, and E-selectin: independence of NOS activity. (A) The effects of L-norvaline on TNFα-induced expression of VCAM-1, ICAM-1, and E-selectin could not be reversed by the NOS inhibitor L-NAME (100 μmol/L). Tubulin in bottom panel served as loading control. Shown are representative blots from five independent experiments. (B) Quantification of the signals shown in panel A. Values are given as percentage relative to stimulation with TNFα in the absence of L-NAME. **p < 0.01, ***p < 0.001 vs. stimulation with TNFα in the absence of L-NAME.Back to article page