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Table 2 Odds ratios (95% confidence interval) of unadjusted and adjusted (for age, smoking and BMI) cross-trait associations

From: A common genetic factor underlies hypertension and other cardiovascular disorders

 

HPT

RP

MIG

CAD

HPT

    

adj

    

RP

0.88 (0.59–1.31)

   

adj

0.99 (0.64–1.54)

   

MIG

1.31 (0.99–1.73)

1.62 (1.21–2.17)

  

adj

1.31 (0.95–1.80)

1.68 (1.23–2.3)

  

CAD

2.85 (1.96–4.16)

2.03 (1.29–3.17)

2.19 (1.53–3.13)

 

adj

2.41 (1.56–3.73)

2.27 (1.42–3.65)

1.77 (1.19–2.63)

 
  1. Calculation of odds ratios included a correction factor for familial clustering. Unadjusted odds ratios are shown above and adjusted below, for each combination of phenotypes. BMI represents body mass index, HPT hypertension, RP Raynaud's phenomenon, MIG migraine, CAD coronary artery disease.