Table 1 Baseline patient characteristics stratified by treatment and genotype.
From: Adipocyte-derived leucine aminopeptidase genotype and response to antihypertensive therapy
Irbesartan | Lys/Lys (n = 3) | Lys/Arg (n = 16) | Arg/Arg (n = 24) |
|---|---|---|---|
Gender (male/female) | 1/2 | 11/5 | 13/11 |
Age (years) | 57.3 [4.1] | 52.6 [1.6] | 53.7 [1.8] |
BMI (kg/m2) | 26.8 [1.8] | 27.2 [0.7] | 27.0 [0.7] |
SBP (mmHg) | 159.6 [10.6] | 161.7 [4.8] | 164.0 [4.0] |
DBP (mmHg) | 105.6 [2.9] | 104.1 [2.0] | 104.2 [1.2] |
IVS (mm) | 1.2 [0.1] | 1.4 [0.05] | 1.4 [0.05] |
PWT (mm) | 1.0 [0.04] | 1.1 [0.03] | 1.1 [0.04] |
LVEDD (mm) | 4.9 [0.2] | 5.1 [0.1] | 5.1 [0.1] |
LVMI (g/m2) | 126.2 [7.6] | 143.5 [5.0] | 154.8 [8.5] |
Atenolol | Lys/Lys (n = 6) | Lys/Arg (n = 19) | Arg/Arg (n = 22) |
Gender (male/female) | 6/0 | 11/8 | 14/8 |
Age (years) | 51.8 [3.5] | 55.5 [1.9] | 52.7 [1.8] |
BMI (kg/m2) | 26.9 [0.9] | 26.9 [0.9] | 27.8 [0.9] |
SBP (mmHg) | 170.1 [8.6] | 159.8 [5.4] | 154.0 [3.2] |
DBP (mmHg) | 109.0 [2.2] | 99.8 [2.0] | 102.6 [1.6] |
IVS (mm) | 1.3 [0.09] | 1.3 [0.05] | 1.3 [0.04] |
PWT (mm) | 1.0 [0.03] | 1.0 [0.03] | 1.1 [0.03] |
LVEDD (mm) | 5.6 [0.3] | 5.1 [0.1] | 5.1 [0.1] |
LVMI (g/m2) | 159.7 [12.5] | 140.5 [5.5] | 146.3 [5.6] |