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Table 3 Changes in LRNC and carotid arterial wall burden

From: Early decrease in carotid plaque lipid content as assessed by magnetic resonance imaging during treatment of rosuvastatin

 

Baseline

3 Months

12 Months

24 Months

LRNC, mm3

111.5 ± 104.2

103.6 ± 95.8*

101.7 ± 93.4*

97.7 ± 91.5*

LRNC%

18.9% ± 11.9%

17.9% ± 11.5%*

17.5% ± 11.2%*

16.7% ± 11.3%*

Wall volume, mm3

533.3 ± 208.9

523.1 ± 196.3

521.0 ± 194.2

528.0 ± 198.9

Lumen volume, mm3

522.1 ± 246.7

514.0 ± 234.2

512.1 ± 245. 6

537.6 ± 265.0

PWV, %

51.0% ± 8.2%

50.8% ± 8.5%

50.9% ± 9.0%

50.3% ± 8.6%

  1. Data are presented as mean ± SD. Changes over time in plaque measurements were compared to baseline using the paired t-test (LRNC, LRNC % and lumen volume were logarithmically transformed to normalize their distributions). LRNC = lipid-rich necrotic core; % LRNC = proportion of LRNC relative to the wall area; PWV = percent wall volume. * P < 0.05 when compared to baseline.