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Table 1 Patient characteristics categorized by plasma NT-pro-BNP levels 1

From: Plasma NT pro-BNP, hs-CRP and big-ET levels at admission as prognostic markers of survival in hospitalized patients with dilated cardiomyopathy: a single-center cohort study

 

All of the patients (n = 560)

NTpro-BNP < 2247 pmol/mL (n = 362)

NT pro-BNP > 2247 pmol/mL (n = 198)

P value

Age (years)

51.0 ± 14.2

51.1 ± 13.4

51.0 ± 15.8

0.958

Female sex, n (%)

146 (26.1)

98 (27.1)

48 (24.2)

0.466

History

    

Course

3 (0.5-7)

2 (0.35-7)

3 (0.6375-6)

0.909

Diabetes mellitus

83 (14.8)

58 (16.0)

25 (12.6)

0.280

Atrial fibrillation, n (%)

121 (21.6)

76 (21.0)

45 (22.7)

0.634

Smoker, n (%)2

265 (47.3)

169 (46.8)

96 (48.9)

0.625

Drinker, n (%)2

170 (30.4)

119 (32.9)

51 (26.0)

0.089

NYHA class III and IV, n (%)3

425 (75.9)

247 (68.2)

178 (89.9)

<0.001

Admission vital signs

    

SBP (mm Hg)3

113.3 ± 17.7

116.0 ± 17.6

108.3 ± 16.7

<0.001

DBP (mm Hg)3

72.3 ± 12.6

73.3 ± 12.5

70.5 ± 12.5

0.012

Heart rate, beat/min

80.8 ± 17.1

79.1 ± 16.0

84.0 ± 18.6

0.002

Laboratory values at admission2

    

Glucose (mmol/L)

5.53 ± 1.70

5.49 ± 1.43

5.62 ± 2.10

0.386

TG (mmol/L)3

1.58 ± 0.89

1.74 ± 0.99

1.27 ± 0.57

<0.001

TC (mmol/L)3

4.59 ± 1.11

4.78 ± 1.08

4.22 ± 1.07

<0.001

Creatinine (μmol/L)

91.9 ± 34.2

87.5 ± 26.5

100.0 ± 44.0

<0.001

BUN (μmol/L)3

8.02 ± 4.07

7.68 ± 3.90

8.63 ± 4.33

0.010

NT Pro-BNP (pmol/mL)3

1652.85 (837.375-2907.2)

1051.45 (700.7-1613.675)

3425.25 (2787.975-4713.125)

<0.001

Electrocardiogram data4

    

QRS duration (ms)

119.6 ± 30.1

117.6 ± 28.3

123.4 ± 33.0

0.029

QT (ms)

408.0 ± 50.7

410.9 ± 49.6

402.6 ± 52.4

0.067

Echocardiography data4

    

LV (mm)3

68.5 ± 9.5

67.1 ± 8.7

71.1 ± 10.3

<0.001

LVEF (mm)3

31.1 ± 8.4

32.6 ± 8.4

28.1 ± 7.6

<0.001

RV (mm)

24.2 ± 5.4

23.1 ± 4.9

26.2 ± 5.8

<0.001

LA (mm)3

44.5 ± 7.8

42.9 ± 7.7

47.4 ± 7.2

<0.001

Medicine at admission2

    

Diuretics, n (%)

529 (94.5)

339 (94.4)

190 (97.4)

0.103

ACEI/ARB, n (%)3

473 (84.5)

315 (87.5)

158 (81.9)

0.073

Beta-blockers, n (%)

509 (90.9)

340 (94.4)

169 (87.1)

0.003

Digoxin, n (%)

449 (80.2)

280 (78.0)

169 (86.7)

0.013

Aspirin/anticoagulation n (%)

353 (63.0)

243 (67.5)

110 (56.4)

0.010

Spironolactone, n (%)

514 (91.8)

331 (91.9)

183 (93.8)

0.414

  1. Note:
  2. 1Data are expressed as the mean ± SD, median (interquartile range) or percentage; P values are from an independent-samples t-test.
  3. 2Smoker was defined using standard questions about current smoking and lifetime smoking at least 100 cigarettes; drinkers who reported drinking 1 drink a day on average on days that they consumed alcohol during the previous year.
  4. 3 Abbreviations: NYHA New York Heart Association, SBP systolic blood pressure DBP diastolic blood pressure, BUN blood urea nitrogen TG triglyceride, TC total cholesterol, NT pro-BNP N-terminal fragment pro-brain natriuretic peptide, LV left ventricle, RV right ventricle, LA left atrium, LVEF left ventricular ejection fraction, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker.
  5. 4Seven patients lacked echocardiography data, 9 patients lacked electrocardiogram data, 4 patient lacked fasting blood glucose, 1 patient lacked creatinine, 2 patients lacked BUN levels, 5 patients lacked triglyceride, total cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol levels and 6 patients lacked medicines at admission.
  6. The bold data indicated that P<0.05.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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