Table 1 Clinical presentation – first cardiac medical examination
From: Rhabdomyomas and Tuberous sclerosis complex: our experience in 33 cases
Case n° | Age at diagnosis | Clinical signs at first examination | ECG and Holter-ECG | Echocardiography at diagnosis | Cardiac surgery |
|---|---|---|---|---|---|
1 | 2Â months | Arrhythmia | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | No |
WPW Syndrome | |||||
2 | 1Â month | Heart murmur | Normal | Multiple rhabdomyomas | No |
3 | 2Â months | Heart murmur | Widened QRS | Multiple rhabdomyomas | No |
4 | Fetal | No symptoms but RVOT obstruction | Normal | Multiple rhabdomyomas | No |
5 | 1Â day | Heart murmur | Normal | Multiple rhabdomyomas | No |
LV obstruction | |||||
6 | 1Â day | Heart murmur | Normal | Multiple rhabdomyomas | No |
7 | Fetal | No symptoms | RV hypertrophy | Lobulated mass in LV | No |
8 | Fetal | No symptoms | Normal | Multiple rhabdomyomas | No |
9 | 1Â month | Heart murmur | RV hypertrophy | Lobulated mass in IVS | No |
10 | 1Â day | Cyanosis | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | No |
LV obstrution | |||||
11 | 2Â months | No symptoms | Atrial ectopic beats | Multiple rhabdomyomas | No |
12 | 1Â months | No symptoms | RV overload signs | Multiple rhabdomyomas | No |
13 | Fetal | Heart failure Cyanosis | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | Yes |
14 | 1Â day | Heart murmur | Normal | Multiple rhabdomyomas | No |
15 | 7Â months | Heart murmur | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | No |
WPW Syndrome | |||||
16 | 1Â day | No symptoms | Incomplete right bundle branch block | Multiple rhabdomyomas | No |
17 | 9Â months | Heart murmur | Normal | Multiple rhabdomyomas | No |
18 | 1Â day | Arhythmia | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | No |
19 | Fetal | No symptoms (hypokinesia) | Normal | Multiple rhabdomyomas | No |
20 | 4Â months | Heart murmur | Ventricular ectopic beats and RV overload signs | Multiple rhabdomyomas | No |
21 | Fetal | No symptoms | WPW Syndrome | Multiple rhabdomyomas | No |
IVS overload signs | |||||
22 | 3Â days | Heart murmur | Normal | Multiple rhabdomyomas | No |
23 | 11Â months | No symptoms | RV overload signs | Multiple rhabdomyomas | No |
24 | 5Â months | No symptoms | Atrial and ventricular ectopic beats | Multiple rhabdomyomas | No |
25 | 1Â day | Heart murmur | Normal | Multiple rhabdomyomas | No |
26 | 9Â months | Seizures | Normal | Multiple rhabdomyomas | No |
27 | Fetal | No symptoms | Normal | Multiple rhabdomyomas | No |
28 | 2Â months | No symptoms | Normal | Multiple rhabdomyomas | No |
29 | Fetal | No symptoms | RV overload signs | Multiple rhabdomyomas | No |
30 | Fetal | Heart murmur | Normal | Multiple rhabdomyomas | No |
31 | 7Â days | Heart murmur | Normal | Multiple rhabdomyomas | No |
32 | 21Â days | No symptoms | RV hypertrophy | Multiple rhabdomyomas | No |
33 | Fetal | Heart murmur | Ventricular ectopic beats | Multiple rhabdomyomas | No |