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Table 2 Baseline characteristics of the DVT population

From: Metformin use in patients with type 2 diabetes mellitus is associated with reduced risk of deep vein thrombosis: a non-randomized, pair-matched cohort study

 

DVT

 
 

No (N = 14885)

Yes (N = 60)

P value

Age, years

57.69 ± 12.98

62.35 ± 13.31

0.006

Male gender

7867 (52.8)

36 (60)

0.328

Hypertension

3560 (23.9)

20 (33.3)

0.120

CAD

1194 (8.0)

12 (20)

0.003

Hyperlipidemia

1745 (11.7)

9 (15)

0.558

Atrial fibrillation

102 (0.7)

2 (3.3)

0.065

Cancer

674 (4.5)

680 (4.6)

0.054

Fracture

894 (6.0)

8 (13.3)

0.027

Major surgery

716 (4.8)

10 (16.7)

0.001

Medications

   

 Aspirin

1381 (9.3)

7 (11.7)

0.679

 Clopidogrel

20 (0.1)

0 (0.0)

1.000

 Warfarin

63 (0.4)

4 (6.7)

<0.001

 Statin

601 (4.0)

4 (6.7)

0.308

 HRT

99 (0.7)

0 (0.0)

1.000

 Metformin

7151 (48.0)

16 (26.7)

0.001

  1. Data are the mean ± SD and n (%).
  2. CAD indicates coronary artery disease; HRT, hormone replacement therapy.
  3. Fracture includes traumatic or pathological fracture involving upper or lower limbs, spine and pelvis.
  4. Major surgery includes cardiothoracic, abdominal, pelvic surgery or orthopedic surgery of lower limbs.