Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation

Table 3 Multivariate cox regression analysis for parameters associated with study endpoint

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-value	HR (95% CI)	p-value
MS	9.119 (3.461-24.024)	<0.001	9.655 (3.000-31.068)	<0.001
Age (years)	1.023 (0.997-1.050)	0.083
*BMI ≥ 30 (kg/m²)	8.1 (3.0-21.454)	<0.001
Hypertension	2.656 (1.068-6.604)	0.036
Dyslipidemia	3.447 (1.417-8.384)	0.006
Diabetes	2.785 (1.015-7.638)	0.047
Creatinine (mg/dl)	0.652 (0.162-2.616)	0.546
*Nitrotyrosine × 100 (μmol/L)	1.136 (1.074-1.202)	<0.001	0.64 (0.12-3.52)	0.611
CRP (mg/dl)	1.253 (1.035-1.516)	0.021	0.940 (0.767- 1.151)	0.977
Heart rate baseline (bpm)	1.011 (0.973-1.051)	0.573
PVC burden (per 100 beats/24 hours increase)	1.017 (0.997-1.038)	0.096

BMI body mass index; CRP C reactive protein; HR Hazard Ratio; PVC premature ventricular contractions.
*MS, BMI and Nitrotyrosine levels were significantly associated with the study endpoint, P<0.001.

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