Asymptomatic subjects with diabetes have a comparable risk of coronary artery disease to Non-diabetic subjects presenting chest pain: a 4-year community-based prospective study

Table 2 Hazard ratios (HR) of CAD events during next 4 years according to the perception of chest pain at baseline

		Subjects without diabetes mellitus				Subjects with diabetes mellitus
		Number of cases	CAD at follow-up (1000 person-yr)	Hazard ratios^a	P ^b	Number of cases	CAD at follow-up (1000 person-yr)	Hazard ratios^a	P ^b
Chest pain, total (%)
	Absence	5624	1.0	2.879	0.001	959	3.9	3.489	0.001
	Presence	1674	2.7	(1.536 – 5.394)	0.001	235	13.0	(1.620 – 7.512)	0.001
Typical chest pain (%)^c
	Absence	6596	1.1	2.814	0.005	1084	4.6	3.279	0.007
	Presence	779	3.2	(1.370 – 5.780)	0.005	120	15.0	(1.380 – 7.793)	0.007
Chest pain on mild-intensity activity (%)^d
	Absence	7146	1.2	6.110	0.003	1171	5.6	1.904	0.530
	Presence	94	8.2	(1.861 –20.054)	0.003	19	13.3	(0.255 – 14.222)	0.530
Chest pain on moderate-intensity exercise (%)^d
	Absence	7067	1.3	2.017	0.338	1158	5.2	3.926	0.028
	Presence	192	2.7	(0.480 – 8.472)	0.338	33	23.8	(1.162 – 13.265)	0.028

Abbreviations: CAD, coronary artery disease.
^aHazard ratio of chest pain for CAD events over the next 4 years adjusting sex and age; ^bsex- and age- adjusted P value; ^cchest pain described as heaviness, tightness, or squeezing regardless of activity level or chest pain perception; ^dany chest pain associated with activity.

ISSN: 1471-2261