Endpoint | Closure Trial | PC Trial | Respect Trial | Random Effects Model | |||||
---|---|---|---|---|---|---|---|---|---|
HR | 95%CI | HR | 95%CI | HR | 95%CI | HR | 95% CI | p-value | |
ITT Population | |||||||||
Composite endpoint of all devices | 0.78 | 0.45,1.35 | 0.63 | 0.24,1.62 | 0.49 | 0.22,1.11 | 0.66 | 0.43,1.01 | 0.06 |
Composite endpoint of Amplatzer device | Â | Â | 0.63 | 0.24,1.62 | 0.49 | 0.22,1.11 | 0.54 | 0.29,1.01 | 0.05 |
Per Protocol | |||||||||
Composite endpoint of all devices | 0.74 | 0.42,1.29 | 0.70 | 0.27,1.85 | 0.37 | 0.14,0.96 | 0.64 | 0.41,0.98 | 0.04 |
Composite endpoint of Amplatzer device | Â | 0.70 | 0.27,1.85 | 0.37 | 0.14,0.96 | 0.64 | 0.44,0.97 | 0.03 |