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Figure 1 | BMC Cardiovascular Disorders

Figure 1

From: Effect of calcification on the mechanical stability of plaque based on a three-dimensional carotid bifurcation model

Figure 1

Histological observation of plaque composites. A: Lipid distribution in a crescent formation within the plaque can cause protrusion into the lumen and tend to obstruct distal arteries after plaque rupture. B: Calcification can be observed by white granules embedded in lipid. C: A zoom-in view of calcified smooth muscles cells reveals the agglomerate of calcium clusters within the plaque. D: Calcification agglomerates are also present in the lesion adjacent to the elastic lamina. (Revised from images by Stary [14])

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