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Table 4 Effect of Doxorubicin, Vitamin E, and Telmisartan on rat serum LDH in IU/L

From: Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response

Groups

LDH level IU/L

Percent of changing

Before treatment

After treatment

 

Doxorubicin 15 mg./kg

578.8 ± 72.3

4328.1 ± 209.5 ††**

647%

Doxo. + Vit E 100 mg./kg

585.1 ± 51.4

1494.9 ± 55.1†† **

155%

Doxo. + Telmisartan 1 mg./kg

570.4 ± 31.9

3108.5 ± 248.9 ††**

444%

  1. The values are expressed as mean ± SEM. † P < 0.05, †† P < 0.01 (means of each group after treatment versus their means before treatment) by using paired t test.
  2. * P < 0.05, ** P < 0.01 (means of Vitamin E, and Telmisartan groups after treatment versus means of Doxorubicin group after treatment) by using LSD test.
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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