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Table 1 Baseline clinical characteristics according to polymorphisms

From: Higher incidence of death in multi-vessel coronary artery disease patients associated with polymorphisms in chromosome 9p21

 

rs10757274

P

rs2383206

P

rs10757278

P

rs1333049

P

 

N = 498

 

N= 495

 

N= 496

 

N = 507

 

Variables

AA

AG

GG

 

AA

AG

GG

 

AA

AG

GG

 

CC

GC

GG

 

Frequency

112

260

126

 

84

237

174

 

115

253

128

 

139

253

115

 

Age (years)

60.1±9.3

59.4±9.0

59.3±8.9

0.73

60.5±8.7

59.1±9.3

59.5±9.1

0.50

59.9±9.3

59.5±9.2

59.4±9.3

0.91

59.1±9.2

60.0±9.2

59.4±9.0

0.65

Men (%)

65.2

66.9

71.4

0.55

65.5

65.4

71.3

0.42

64.3

66.8

70.3

0.60

70.5

65.6

67.8

0.61

Smoking (%)

34.8

28.5

42.9

0.02

28.6

31.6

37.4

0.30

32.2

30.4

39.8

0.18

40.3

28.9

33.0

0.07

Hy (%)

67.9

55.4

59.5

0.08

73.8

50.2

62.1

<0.01

67.0

53.8

60.2

0.05

60.4

54.2

65.2

0.12

DM (%)

49.1

39.2

29.4

0.01

52.4

40.1

32.8

0.01

47.8

37.9

32.0

0.04

34.5

36.4

49.6

0.03

BMI (kg/m2)

27.1±4.0

27.2±4.2

27.3±4.0

0.94

27.4±3.9

27.0±4.1

27.4±4.2

0.49

27.3±4.0

26.9±4.1

27.6±4.2

0.26

27.5±4.2

27.0±4.1

27.2±4.2

0.48

MI (%)

42.9

42.3

54.0

0.08

41.7

42.6

51.7

0.13

47.8

41.1

53.1

0.07

54.0

40.7

48.7

0.03

TC (mg/dL)

219.8±48.5

225.5±51.5

222.7±47.0

0.58

220.9±50.5

223.1±51.7

225.8±45.6

0.73

220.0±50.8

226.0±51.8

223.7±44.0

0.56

223.0±43.9

225.7±51.6

219.3±49.9

0.52

LDLc (mg/dL)

144.6±45.5

149.9±47.6

144.6±37.0

0.44

144.8±46.8

148.3±47.7

148.3±37.3

0.81

145.7±47.6

149.9±46.7

145.6±35.8

0.58

145.7±36.4

149.6±47.0

145.2±45.6

0.60

HDLc (mg/dL)

36.4±10.8

37.1±9.8

38.0±10.1

0.47

35.6±8.7

37.3±10.4

38.2±11.0

0.18

36.3±10.7

37.0±9.4

38.711.7

0.20

38.7±11.5

37.3±10.0

36.0±8.9

0.14

TG (mg/dL)

197.7±112.5

194.3±123.8

196.0±110.2

0.96

204.9±116.6

188.3±115.2

195.3±121.5

0.53

194.9±112.7

193.4±115.9

195.1±125.9

0.99

195.1±124.2

191.4±116.0

198.2±112.2

0.87

PCI (%)

29.5

33.1

37.3

0.51

27.4

35.0

35.1

0.23

33.9

30.8

39.8

0.30

38.8

32.0

32.2

0.43

CABG (%)

32.1

34.2

34.9

 

36.9

29.5

37.4

 

29.6

34.8

33.6

 

35.3

33.6

33.0

 

CT (%)

38.4

32.7

27.8

 

35.7

35.4

27.6

 

36.5

34.4

26.6

 

25.9

34.4

34.8

 

2-Vessel (%)

44.6

49.2

31.7

0.05

45.2

48.5

36.8

0.06

47.8

47.4

32.8

0.02

36.0

46.2

52.2

0.03

3-Vessel (%)

55.4

50.8

68.3

 

54.8

51.5

63.2

 

52.2

52.6

67.2

 

64.0

53.8

47.8

 
  1. N = number of samples genotyped.
  2. Data are shown as mean ± standard deviation, unless otherwise indicated.
  3. Hy = Hypertension; DM = Diabetes mellitus; MI = Myocardial infarction; TC = Total Cholesterol; LDLc = Low density lipoprotein; HDLc = High density lipoprotein; TG = Triglycerides; PCI = Angioplasty; CABG = Revascularization; CT = Clinical treatment; 2 or 3-vessel = coronary anatomy disease.
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BMC Cardiovascular Disorders

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