ACE gene insertion/deletion polymorphism has a mild influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI

Table 2 Invasive and echocardiographic measurements

	All patients	DD/ID genotype	II genotype	p*
	N = 556	N = 393	N = 163	DD/ID vs. II
DCV	1.89 ± 0.80	1.92 ± 0.80	1.83 ± 0.80	0.236
IRA - LM	2 (0.4%)	2 (0.5%)	0	0.893
IRA - LAD (%)	256 (46.0%)	183 (46.6%)	73 (44.8%)	0.772
IRA - RCx (%)	74 (13.3%)	51 (13.0%)	23 (14.1%)	0.825
IRA - RCA (%)	224 (40.3%)	157 (39.9%)	67 (41.1%)	0.875
Initial TIMI
0-1	380 (68.3%)	270 (68.7%)	110 (67.5%)	0.050
2	91 (16.4%)	71 (18.1%)	20 (12.3%)
3	85 (15.3%)	52 (13.2%)	33 (20.2%)
TIMI after PCI
0-1	13 (2.3%)	10 (2.5%)	3 (1.8%)	0.830
2	51 (9.2%)	37 (9.4%)	14 (8.6%)
3	492 (88.5%)	346 (88.0%)	146 (89.6%)
EF (angiography)	49.4 ± 12.2	49.3 ± 21.4	49.7 ± 12.0	0.644
EDV/BSA (mL/m²)	62.4 ± 17.0	62.1 ± 16.9	63.2 ± 17.5	0.583
ESV/BSA (mL/m²)	29.6 ± 12.5	30.0 ± 12.3	28.5 ± 13.0	0.049
EF (echo) (%)	50.9 ± 11.3	50.2 ± 11.1	52.7 ± 11.7	0.006

Continuous variables are presented as mean, SD, median, 5-95 percentiles, and categorized as percentage proportion. *The Mann-Whitney U test or chi-square test were used for testing differencies between genotype groups
DCV: Diseased coronary vessels; IRA: infarct-related artery; LM: left main; LAD: left anterior descending coronary artery; RCx: ramus cirumflexus; RCA: right coronary artery; EF: ejection fraction of the left ventricle; EDV: end-diastolic volume; ESV: end-systolic volume; BSA: Body surface area.

ISSN: 1471-2261