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Table 1 Sensitivity analysis

From: Duration of clopidogrel treatment and risk of mortality and recurrent myocardial infarction among 11 680 patients with myocardial infarction treated with percutaneous coronary intervention: a cohort study

 

PCI Day 0-1

 

PCI Day 2-29

 

Landmark analyses

Log rank

P-value

Log rank

P-value

Day 91-180

    

   Death

 

0.11

 

0.002

   Recurrent MI

 

0.17

 

0.07

   Combined

 

0.06

 

0.007

Day 181-540

    

   Death

 

0.25

 

0.001

   Recurrent MI

 

0.33

 

0.99

   Combined

 

0.65

 

0.1

Cox Proportional Hazards Model

HR (CI)*

P-value

HR (CI)*

P-value

Day 91-180

    

   Death

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

0.49 (0.23-0.97)

0.04

0.28 (0.12-0.64)

0.003

   Recurrent MI

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

0.71 (0.42-1.19)

0.19

0.75 (0.40-1.38)

0.35

   Combined

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

0.66 (0.43-1.02)

0.06

0.62 (0.37-1.04)

0.07

Day 181-540

    

   Death

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

0.83 (0.55-1.23)

0.34

0.55 (0.35-0.86)

0.01

   Recurrent MI

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

1.17 (0.76-1.81)

0.48

0.79 (0.50-1.24)

0.3

   Combined

    

No clopidogrel

1.00

 

1.00

 

Clopidogrel

0.92 (0.68-1.25)

0.58

0.73 (0.53-1.02)

0.07

  1. * Hazard ratio (confidence intervals).