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  1. Polymorphonuclear neutrophils, stimulated by the activated complement factor C5a, have been implicated in cardiac ischemia/reperfusion injury. ADC-1004 is a competitive C5a receptor antagonist that has been sh...

    Authors: Jesper van der Pals, Sasha Koul, Patrik Andersson, Matthias Götberg, Joey FA Ubachs, Mikael Kanski, Håkan Arheden, Göran K Olivecrona, Bengt Larsson and David Erlinge

    Citation: BMC Cardiovascular Disorders 2010 10:45

    Content type: Research article

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  2. Lowering of blood pressure by antihypertensive drugs reduces the risks of cardiovascular events, stroke, and total mortality. However, poor adherence to antihypertensive medications reduces their effectiveness...

    Authors: Alfonso Leiva, Marta Fajó, Luís Escriche, Francisco J Audera, Sara López, Ma Carmén Martín, Rosa González, Gaspar Tamborero, Elena M García, Rosa Duro, Ramón Orueta, Francisca Serra, Pilar D'agosto P, Jerónima Miralles, Patricia Lorente, Joan Llobera…

    Citation: BMC Cardiovascular Disorders 2010 10:44

    Content type: Study protocol

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  3. Expanded endothelial progenitor cells (eEPC) improve global left ventricular function in experimental myocardial infarction (MI). Erythropoietin beta (EPO) applied together with eEPC may improve regional myoca...

    Authors: Andreas Stein, Martina Knödler, Markus Makowski, Sandra Kühnel, Stefan Nekolla, Alexandra Keithahn, Eliane Weidl, Philip Groha, Maren Schürmann, Atti Saraste, Rene Botnar, Robert AJ Oostendorp and Ilka Ott

    Citation: BMC Cardiovascular Disorders 2010 10:43

    Content type: Research article

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  4. To evaluate the midterm results of patients with angina and diffuse coronary artery disease treated with transmyocardial revascularization in combination with autologous stem cell therapy.

    Authors: Guillermo Reyes, Keith B Allen, Pablo Álvarez, Adrian Alegre, Beatriz Aguado, MariaJose Olivera, Paloma Caballero, JoseLuis Rodríguez and Juan Duarte

    Citation: BMC Cardiovascular Disorders 2010 10:42

    Content type: Research article

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  5. The clinical impact of PlA2 polymorphism has been investigated in several diseases, but the definition of its specific role on thrombotic cardiovascular complications has been challenging. We aimed to explore ...

    Authors: Gennaro Galasso, Gaetano Santulli, Federico Piscione, Roberta De Rosa, Valentina Trimarco, Raffaele Piccolo, Salvatore Cassese, Guido Iaccarino, Bruno Trimarco and Massimo Chiariello

    Citation: BMC Cardiovascular Disorders 2010 10:41

    Content type: Research article

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  6. Peripheral arterial disease (PAD) is caused by narrowing of the arteries in the lower extremities. Limited data exist concerning the impact of diffuse vascular disease (DVD) on prognosis and costs. Thus, the o...

    Authors: Kristen Migliaccio-Walle, Michael Stokes, Irina Proskorovsky, Dan Popovici-Toma and Wissam El-Hadi

    Citation: BMC Cardiovascular Disorders 2010 10:40

    Content type: Research article

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  7. Survivors of a cardiac arrest often have persistent cardiovascular derangements following cardiopulmonary resuscitation including decreased cardiac output, arrhythmias and morphological myocardial damage. Thes...

    Authors: Keld Fosgerau, Giuseppe Ristagno, Magdalena Jayatissa, Mads Axelsen, Jacob W Gotfredsen, Uno J Weber, Lars Køber, Christian Torp-Pedersen and Charlotte Videbaek

    Citation: BMC Cardiovascular Disorders 2010 10:39

    Content type: Research article

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  8. As populations in Western countries continue to change in their ethnic composition, there is a need for regular surveillance of diseases that have previously shown some health disparities. Earlier data have al...

    Authors: Aman PK Nijjar, Hong Wang, Hude Quan and Nadia A Khan

    Citation: BMC Cardiovascular Disorders 2010 10:38

    Content type: Research article

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  9. Blood pressure (BP) lowering in people who have had a stroke or transient ischaemic attack (TIA) leads to reduced risk of further stroke. However, it is not clear what the target BP should be, since intensific...

    Authors: Kate Fletcher, Jonathan Mant, Richard McManus, Sarah Campbell, Jonathan Betts, Clare Taylor, Satnam Virdee, Sue Jowett, Una Martin, Sheila Greenfield, Gary Ford, Nick Freemantle and FD Richard Hobbs

    Citation: BMC Cardiovascular Disorders 2010 10:37

    Content type: Study protocol

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  10. Lower extremity peripheral arterial disease (PAD) is a marker of widespread atherosclerosis. Individuals with PAD, most of whom do not show typical PAD symptoms ('asymptomatic' patients), are at increased risk...

    Authors: Claudio Cimminiello, Claudio Borghi, Serge Kownator, Jean Claude Wautrecht, Christos P Carvounis, Stefanus E Kranendonk, Beat Kindler and Mario Mangrella

    Citation: BMC Cardiovascular Disorders 2010 10:35

    Content type: Study protocol

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  11. The syndrome of vital exhaustion (VE), characterized by fatigue and irritability, may contribute to an increased risk of atherosclerosis. The aim of the study was to explore sex differences in the interactions...

    Authors: Nadja Chumaeva, Mirka Hintsanen, Markus Juonala, Olli T Raitakari and Liisa Keltikangas-Järvinen

    Citation: BMC Cardiovascular Disorders 2010 10:34

    Content type: Research article

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  12. Moxibustion is a traditional East Asian medical therapy that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points. The aim of this review was to eva...

    Authors: Jong-In Kim, Jun-Yong Choi, Hyangsook Lee, Myeong Soo Lee and Edzard Ernst

    Citation: BMC Cardiovascular Disorders 2010 10:33

    Content type: Research article

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  13. Heart failure with preserved left ventricular ejection fraction and abnormal diastolic function is commonly observed after recovery from an acute myocardial infarction. The aim of this study was to investigate...

    Authors: Myrielle Mathieu, Bachar El Oumeiri, Karim Touihri, Ielham Hadad, Maryam Mahmoudabady, Philippe Thoma, Thierry Metens, Jozef Bartunek, Guy R Heyndrickx, Serge Brimioulle, Robert Naeije and Kathleen Mc Entee

    Citation: BMC Cardiovascular Disorders 2010 10:32

    Content type: Research article

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  14. To analyze the in-hospital complication rate in women suffering from non-ST elevation myocardial infarction treated with percutaneous coronary intervention (PCI) compared to men.

    Authors: Caroline Berthillot, Dominique Stephan, Michel Chauvin and Gerald Roul

    Citation: BMC Cardiovascular Disorders 2010 10:31

    Content type: Research article

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  15. Development of experimental animal models has played an important role in understanding the mechanisms of cardiac memory. The purpose of this study was to evaluate a new canine model of cardiac memory using en...

    Authors: Li Yue-Chun, Ge Li-Sha, Guang Xue-Qiang, Chen Peng, Wu Lian-Pin, Yang Peng-Lin, Tang Ji-Fei and Lin Jia-Feng

    Citation: BMC Cardiovascular Disorders 2010 10:30

    Content type: Research article

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  16. Prior studies have found that patients taking single-pill amlodipine/atorvastatin (SPAA) have greater likelihood of adherence at 6 months than those taking 2-pill calcium-channel blocker and statin combination...

    Authors: Richard H Chapman, Jason Yeaw and Craig S Roberts

    Citation: BMC Cardiovascular Disorders 2010 10:29

    Content type: Research article

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  17. Resting conventional 12-lead ECG has low sensitivity for detection of coronary artery disease (CAD) and left ventricular hypertrophy (LVH) and low positive predictive value (PPV) for prediction of left ventric...

    Authors: Todd T Schlegel, Walter B Kulecz, Alan H Feiveson, E Carl Greco, Jude L DePalma, Vito Starc, Bojan Vrtovec, M Atiar Rahman, Michael W Bungo, Matthew J Hayat, Terry Bauch, Reynolds Delgado, Stafford G Warren, Tulio Núñez-Medina, Rubén Medina, Diego Jugo…

    Citation: BMC Cardiovascular Disorders 2010 10:28

    Content type: Research article

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  18. Face-to-face outpatient cardiac rehabilitation (OCR) programs are an important and effective component in the management of cardiovascular disease. However, these programs have low participation rates, especia...

    Authors: Corneel Vandelanotte, Trudy Dwyer, Anetta Van Itallie, Christine Hanley and W Kerry Mummery

    Citation: BMC Cardiovascular Disorders 2010 10:27

    Content type: Research article

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  19. We sought to determine the difference in the localization of coronary artery disease (CAD) between the left and right coronary artery system and investigate the effect of sex and age on that difference.

    Authors: George D Giannoglou, Antonios P Antoniadis, Yiannis S Chatzizisis and George E Louridas

    Citation: BMC Cardiovascular Disorders 2010 10:26

    Content type: Research article

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  20. The global burden of cardiovascular disease (CVD) continues to rise. Successful treatment of CVD requires adequate pharmaceutical management. The aim was to examine the availability, pricing and affordability ...

    Authors: Maaike SM van Mourik, Alexandra Cameron, Marg Ewen and Richard O Laing

    Citation: BMC Cardiovascular Disorders 2010 10:25

    Content type: Research article

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  21. Multiple randomized controlled trials (RCTs) have examined the cardiovascular effects of omega-3 fatty acids and have provided unexplained conflicting results. A meta-analysis of these RCTs to estimate efficac...

    Authors: Kristian B Filion, Fouad El Khoury, Michael Bielinski, Ian Schiller, Nandini Dendukuri and James M Brophy

    Citation: BMC Cardiovascular Disorders 2010 10:24

    Content type: Research article

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  22. Genotype-phenotype association studies are typically based upon polymorphisms or haplotypes comprised of multiple polymorphisms within a single gene. It has been proposed that combinations of polymorphisms in ...

    Authors: Ines N Hahntow, Gideon Mairuhu, Irene GM van Valkengoed, Richard P Koopmans and Martin C Michel

    Citation: BMC Cardiovascular Disorders 2010 10:23

    Content type: Research article

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  23. Hashimoto's thyroiditis is the most important cause of hypothyroidism. It is a systemic disease that can even affect the cardiovascular system, by accelerating the atherosclerotic process. Aim of this study wa...

    Authors: Marco M Ciccone, Giovanni De Pergola, Maria T Porcelli, Pietro Scicchitano, Pasquale Caldarola, Massimo Iacoviello, Guida Pietro, Francesco Giorgino and Stefano Favale

    Citation: BMC Cardiovascular Disorders 2010 10:22

    Content type: Research article

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  24. Atrial fibrillation (AF) patients with a high risk of stroke are recommended anticoagulation with warfarin. However, the benefit of warfarin is dependent upon time spent within the target therapeutic range (TT...

    Authors: Danielle E Smith, Christian Borg Xuereb, Helen M Pattison, Gregory YH Lip and Deirdre A Lane

    Citation: BMC Cardiovascular Disorders 2010 10:21

    Content type: Study protocol

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  25. Liberation from the ventilator is a difficult task, whereas early echocardiographic indices of weaning readiness are still lacking. The aim of this study was to test whether tricuspid annular plane systolic ex...

    Authors: Vasilios E Papaioannou, Dimitrios A Stakos, Christos K Dragoumanis and Ioannis A Pneumatikos

    Citation: BMC Cardiovascular Disorders 2010 10:20

    Content type: Research article

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  26. Proteolytic degradation of Type I Collagen by proteases may play an important role in remodeling of atherosclerotic plaques, contributing to increased risk of plaque rupture.

    Authors: Natasha Barascuk, Helene Skjøt-Arkil, Thomas C Register, Lise Larsen, Inger Byrjalsen, Claus Christiansen and Morten A Karsdal

    Citation: BMC Cardiovascular Disorders 2010 10:19

    Content type: Research article

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  27. Selection of the right warfarin dose at the outset of treatment is not straightforward, and current evidence is lacking to determine the optimal strategy for initiation of therapy.

    Authors: Carl Heneghan, Sally Tyndel, Clare Bankhead, Yi Wan, David Keeling, Rafael Perera and Alison Ward

    Citation: BMC Cardiovascular Disorders 2010 10:18

    Content type: Research article

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  28. Maintaining a healthy weight and undertaking regular physical activity are important for the secondary prevention of cardiovascular disease (CVD). However, many people with CVD are overweight and insufficientl...

    Authors: Janice Sangster, Susan Furber, Margaret Allman-Farinelli, Marion Haas, Philayrath Phongsavan, Andy Mark and Adrian Bauman

    Citation: BMC Cardiovascular Disorders 2010 10:17

    Content type: Study protocol

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  29. Acute mental stress may contribute to the cardiovascular disease progression via autonomic nervous system controlled negative effects on the endothelium. The joint effects of stress-induced sympathetic or para...

    Authors: Nadja Chumaeva, Mirka Hintsanen, Taina Hintsa, Niklas Ravaja, Markus Juonala, Olli T Raitakari and Liisa Keltikangas-Järvinen

    Citation: BMC Cardiovascular Disorders 2010 10:16

    Content type: Research article

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  30. Aorto-bifemoral bypass (AFB) is commonly performed to treat aorto-iliac disease and a durable long-term outcome is achieved. Most studies documenting beneficial outcomes after AFB have been limited to mortalit...

    Authors: Fernando J Abelha, Miguela Botelho, Vera Fernandes and Henrique Barros

    Citation: BMC Cardiovascular Disorders 2010 10:15

    Content type: Research article

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  31. Bilateral stroke following radiofrequency catheter ablation is an unusual complication and may result in bilateral altitudinal visual field defects. Bilateral altitudinal visual field defects usually result fr...

    Authors: Susie T Luu, Andrew W Lee and Celia S Chen

    Citation: BMC Cardiovascular Disorders 2010 10:14

    Content type: Case report

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  32. Patients with acute coronary syndrome (ACS) in India have increased pre-hospital delay and low rates of thrombolytic reperfusion. Use of ECG could reduce pre-hospital delay among patients who first present to ...

    Authors: Joshua Schulman-Marcus, Dorairaj Prabhakaran and Thomas A Gaziano

    Citation: BMC Cardiovascular Disorders 2010 10:13

    Content type: Research article

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  33. Heart failure (HF) is a major cause of hospitalization and death in the aging population around the world. Home care utilization is associated with improved survival for the patients with HF, and varies by eth...

    Authors: Guanmin Chen, Nadia Khan, Kathryn M King, Brenda R Hemmelgarn and Hude Quan

    Citation: BMC Cardiovascular Disorders 2010 10:12

    Content type: Research article

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  34. Clinical trials comparing thrombectomy devices with conventional percutaneous coronary interventions (PCI) in patients with acute ST elevation myocardial infarction (STEMI) have produced conflicting results. T...

    Authors: Umesh U Tamhane, Stanley Chetcuti, Irfan Hameed, P Michael Grossman, Mauro Moscucci and Hitinder S Gurm

    Citation: BMC Cardiovascular Disorders 2010 10:10

    Content type: Research article

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  35. Pulmonary arterial hypertension (PAH) has witnessed dramatic treatment advances over the past decade. However, with the exception of epoprostenol, data from short-term randomized controlled trials (RCTs) have ...

    Authors: Peter Steele, Geoff Strange, John Wlodarczyk, Brad Dalton, Simon Stewart, Eli Gabbay and Anne Keogh

    Citation: BMC Cardiovascular Disorders 2010 10:9

    Content type: Research article

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  36. To evaluate the influence of heart disease on clinical characteristics, quality of life, use of health resources, and costs of patients with COPD followed at primary care settings under common clinical practic...

    Authors: Javier de Miguel-Díez, Pilar Carrasco-Garrido, Javier Rejas-Gutierrez, Antonio Martín-Centeno, Elena Gobartt-Vázquez, Valentín Hernandez-Barrera, Angel Gil de Miguel and Rodrigo Jimenez-Garcia

    Citation: BMC Cardiovascular Disorders 2010 10:8

    Content type: Research article

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  37. Atrial fibrillation (AF) occurs in about 27% to 40% of post cardiac surgery patients. AF following coronary artery bypass graft surgery (CABG) is associated with a two-fold increase in morbidity and mortality....

    Authors: Nasir Shariff, Steven Zelenkofske, Sherrine Eid, Michael J Weiss and Muneeruddin Q Mohammed

    Citation: BMC Cardiovascular Disorders 2010 10:7

    Content type: Research article

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  38. The optimal duration of clopidogrel treatment after percutaneous coronary intervention (PCI) is unclear. We studied the risk of death or recurrent myocardial infarction (MI) in relation to 6- and 12-months clo...

    Authors: Rikke Sørensen, Steen Z Abildstrom, Peter Weeke, Emil L Fosbøl, Fredrik Folke, Morten L Hansen, Peter R Hansen, Jan K Madsen, Ulrik Abildgaard, Lars Køber, Henrik E Poulsen, Christian Torp-Pedersen and Gunnar H Gislason

    Citation: BMC Cardiovascular Disorders 2010 10:6

    Content type: Research article

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  39. Cardiac rehabilitation programs offer effective means to prevent recurrence of a cardiac event, but poor uptake of current programs have been reported globally. Home based models are considered as a feasible a...

    Authors: Darren L Walters, Antti Sarela, Anita Fairfull, Kylie Neighbour, Cherie Cowen, Belinda Stephens, Tom Sellwood, Bernadette Sellwood, Marie Steer, Michelle Aust, Rebecca Francis, Chi-Keung Lee, Sheridan Hoffman, Gavin Brealey and Mohan Karunanithi

    Citation: BMC Cardiovascular Disorders 2010 10:5

    Content type: Study protocol

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  40. The time course of regional functional recovery following revascularization with regards to the presence or absence of infarction is poorly known. We studied the effect of the presence of chronic non-transmura...

    Authors: Martin Ugander, Peter A Cain, Per Johnsson, John Palmer and Håkan Arheden

    Citation: BMC Cardiovascular Disorders 2010 10:4

    Content type: Research article

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  41. Indian Asians are at increased risk of cardiovascular death which does not appear to be explained by conventional risk factors. As microvascular disease is also more prevalent in Indian Asians, and as it is th...

    Authors: William D Strain, Alun D Hughes, Jamil Mayet, Andrew R Wright, Jaspal Kooner, Nish Chaturvedi and Angela C Shore

    Citation: BMC Cardiovascular Disorders 2010 10:3

    Content type: Research article

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  42. The population incidence of coronary heart disease (CHD) has been declining in Australia and many other countries. This decline has been due to reduced population levels of risk factors for CHD and improved me...

    Authors: Haider R Mannan, Matthew Knuiman and Michael Hobbs

    Citation: BMC Cardiovascular Disorders 2010 10:2

    Content type: Research article

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  43. Ectonucleotidase dependent adenosine generation has been implicated in preconditioning related cardioprotection against ischemia-reperfusion injury, and treatment with a soluble ectonucleotidase has been shown...

    Authors: Jesper van der Pals, Sasha Koul, Michael I Götberg, Göran K Olivecrona, Martin Ugander, Mikael Kanski, Andreas Otto, Matthias Götberg, Håkan Arheden and David Erlinge

    Citation: BMC Cardiovascular Disorders 2010 10:1

    Content type: Research article

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  44. Despite the potentially life-saving benefits of the implantable cardioverter-defibrillator (ICD), a significant group of patients experiences emotional distress after ICD implantation. Different psychosocial i...

    Authors: Elena Salmoirago-Blotcher and Ira S Ockene

    Citation: BMC Cardiovascular Disorders 2009 9:56

    Content type: Research article

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  45. Lipids, particularly low-density (LDL) and high-density (HDL) lipoproteins, are associated with increased risk of stroke and cardiovascular disease, probably due to atherosclerosis. The objective of this cross...

    Authors: Hannah Gardener, David Della Morte, Mitchell SV Elkind, Ralph L Sacco and Tatjana Rundek

    Citation: BMC Cardiovascular Disorders 2009 9:55

    Content type: Research article

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  46. Coronary artery anomalies (CAAs) are currently undergoing profound changes in understanding potentially pathophysiological mechanisms of disease. Aim of this study was to investigate the prevalence of anomalou...

    Authors: Franz von Ziegler, Marco Pilla, Lori McMullan, Prasad Panse, Alexander W Leber, Norbert Wilke and Alexander Becker

    Citation: BMC Cardiovascular Disorders 2009 9:54

    Content type: Research article

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  47. Coronary artery bypass graft (CABG) surgery is the standard of care in the treatment of advanced coronary artery disease, and its long-term results are affected by the failure of bypass grafts. The aim of the ...

    Authors: Hosseinali Bassri, Farzad Salari, Fereidoun Noohi, Marzieh Motevali, Seifollah Abdi, Nader Givtaj, Kamal Raissi and Majid Haghjoo

    Citation: BMC Cardiovascular Disorders 2009 9:53

    Content type: Research article

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  48. The study aimed to determine the frequency and characteristics of heart failure with normal EF in a native African population with heart failure.

    Authors: Adedeji K Adebayo, Adewole A Adebiyi, Olulola O Oladapo, Okechukwu S Ogah, Akinyemi Aje, Dike B Ojji and Ayodele O Falase

    Citation: BMC Cardiovascular Disorders 2009 9:52

    Content type: Research article

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