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  1. Autonomic dysfunction appears to play a significant role in the development of atrial fibrillation (AF), and impaired heart rate recovery (HRR) during exercise treadmill testing (ETT) is a known marker for aut...

    Authors: Thomas M Maddox, Colleen Ross, P Michael Ho, David Magid and John S Rumsfeld
    Citation: BMC Cardiovascular Disorders 2009 9:11
    Content type: Research article Published on:

  2. We examined whether impaired renal function causes thickening of the aortic valve leaflets in hyperlipidemic apoE-knockout (apoE-/-) mice, and whether the putative effect on the aortic valves could be prevented b...

    Authors: Mikko A Simolin, Tanja X Pedersen, Susanne Bro, Mikko I Mäyränpää, Satu Helske, Lars B Nielsen and Petri T Kovanen
    Citation: BMC Cardiovascular Disorders 2009 9:10
    Content type: Research article Published on:

  3. Disease severity and functional impairment in patients with intermittent claudication is usually quantified by the measurement of pain-free walking distance (intermittent claudication distance, ICD) and maxima...

    Authors: Lotte M Kruidenier, Saskia PA Nicolaï, Edith M Willigendael, Rob A de Bie, Martin H Prins and Joep AW Teijink
    Citation: BMC Cardiovascular Disorders 2009 9:9
    Content type: Research article Published on:

  4. Moderate alcohol consumption is protective against coronary artery disease. Endothelial dysfunction contributes to atherosclerosis and the pathogenesis of cardiovascular disease. The effects of alcohol consump...

    Authors: Keiko Suzuki, Mitchell SV Elkind, Bernadette Boden-Albala, Zhezhen Jin, Grace Berry, Marco R Di Tullio, Ralph L Sacco and Shunichi Homma
    Citation: BMC Cardiovascular Disorders 2009 9:8
    Content type: Research article Published on:

  5. The association of elevated serum levels of secretory phospholipase A2 (sPLA2) in patients with cardiovascular disease and their presence in atherosclerotic lesions suggest the participation of sPLA2 enzymes in t...

    Authors: Jose O Leite, Ushma Vaishnav, Michael Puglisi, Heather Fraser, Joaquim Trias and Maria Luz Fernandez
    Citation: BMC Cardiovascular Disorders 2009 9:7
    Content type: Research article Published on:

  6. Controlling blood pressure with drugs is a key aspect of cardiovascular disease prevention, but until recently has been the sole preserve of health professionals. Self-management of hypertension is an under re...

    Authors: Richard J McManus, Emma P Bray, Jonathan Mant, Roger Holder, Sheila Greenfield, Stirling Bryan, Miren I Jones, Paul Little, Bryan Williams and FD Richard Hobbs
    Citation: BMC Cardiovascular Disorders 2009 9:6
    Content type: Study protocol Published on:

  7. Studies have demonstrated that the use of implantable cardioverter defibrillators (ICDs) is effective for the primary prevention of arrhythmic events but due to imposing costs, there remains a need to identify...

    Authors: Charlotte J van der Avoort, Kristian B Filion, Nandini Dendukuri and James M Brophy
    Citation: BMC Cardiovascular Disorders 2009 9:5
    Content type: Research article Published on:

  8. The use of omega-3 fatty acids is a currently proven strategy for secondary prevention of heart disease. The prescription practices for this important nutraceutical is not currently known. It is imperative to ...

    Authors: Saqib A Gowani, Sana Shoukat, Ather M Taqui, Hashim M Hanif, Wasiq F Rawasia, Zeeshan Qadri and Sajid H Dhakam
    Citation: BMC Cardiovascular Disorders 2009 9:4
    Content type: Research article Published on:

  9. Case-control Genome-Wide Association Studies (GWAS) have identified single nucleotide polymorphisms (SNPs) at the 9p21 locus as risk factors for coronary artery disease (CAD). The locus does not contain a clea...

    Authors: Suet Nee Chen, Christie M Ballantyne, Antonio M Gotto Jr and Ali J Marian
    Citation: BMC Cardiovascular Disorders 2009 9:3
    Content type: Research article Published on:

  10. Heterogeneity in B-type natriuretic peptide (BNP) levels, especially among individuals with acute heart failure with normal left ventricular ejection fraction (HFNEF), can cause confusion in interpreting resul...

    Authors: Ken Shimamoto, Natsuha Koike, Kiyoko Mizuochi, Miho Honma, Yufuko Kasai, Akiko Sakai, Etsuko Fujita and Masatoshi Kawana
    Citation: BMC Cardiovascular Disorders 2009 9:2
    Content type: Research article Published on:

  12. Cytochrome P450 (CYP) enzyme 2J2, an epoxygenase predominantly expressed in the heart, metabolises arachidonic acid to biologically active eicosanoids. One of the CYP2J2 products, 11, 12-epoxyeicosatrienoic ac...

    Authors: Jan Börgel, Daniel Bulut, Christoph Hanefeld, Horst Neubauer, Andreas Mügge, Jörg T Epplen, Tim Holland-Letz and Martin Spiecker
    Citation: BMC Cardiovascular Disorders 2008 8:41
    Content type: Research article Published on:

  13. The alpha1A-adrenergic receptor (α1A-AR) regulates the cardiac and peripheral vascular system through sympathetic activation. Due to its important role in the regulation of vascular tone and blood pressure, we ai...

    Authors: Silvia R Freitas, Alexandre C Pereira, Marcilene S Floriano, José G Mill and José E Krieger
    Citation: BMC Cardiovascular Disorders 2008 8:40
    Content type: Research article Published on:

  14. Enhanced external counter pulsation (EECP) is a non-invasive treatment option for patients with refractory angina pectoris ineligible to further traditional treatment. The aim of this study was to evaluate the...

    Authors: André Erdling, Susanne Bondesson, Thomas Pettersson and Lars Edvinsson
    Citation: BMC Cardiovascular Disorders 2008 8:39
    Content type: Research article Published on:

  15. Coronary artery calcification (CAC) measured by electron-beam computed tomography (EBCT) has been well studied in the prediction of coronary artery disease (CAD). We sought to evaluate the impact of the CAC sc...

    Authors: Lieuwe H Piers, Farah Salachova, Riemer HJA Slart, Rozemarijn Vliegenthart, Riksta Dikkers, Frederique AP Hospers, Hjalmar R Bouma, Clark J Zeebregts, Tineke P Willems, Matthijs Oudkerk, Felix Zijlstra and René A Tio
    Citation: BMC Cardiovascular Disorders 2008 8:38
    Content type: Research article Published on:

  16. The Gly482Ser polymorphism in peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A) has been demonstrated to be associated with diabetes, obesity and hypertension, all of which are impor...

    Authors: Erik Ingelsson, Louise Bennet, Martin Ridderstråle, Marianne Söderström, Lennart Råstam and Ulf Lindblad
    Citation: BMC Cardiovascular Disorders 2008 8:37
    Content type: Research article Published on:

  17. Endothelial dysfunction plays a central role in atherosclerotic progression and cardiovascular complications of type 2 diabetes mellitus (T2DM). Given the role of nitric oxide in the vascular system, we aimed ...

    Authors: Jacob Odeberg, Charlotte A Larsson, Lennart RÃ¥stam and Ulf Lindblad
    Citation: BMC Cardiovascular Disorders 2008 8:36
    Content type: Research article Published on:

  18. Anoxic coma following cardiac arrest is a common problem with ethical, social, and legal consequences. Except for unfavorable somatosensory-evoked potentials (SSEP) results, predictors of unfavorable outcome w...

    Authors: Cédric Daubin, Damien Guillotin, Olivier Etard, Cathy Gaillard, Damien du Cheyron, Michel Ramakers, Bruno Bouchet, Jean-Jacques Parienti and Pierre Charbonneau
    Citation: BMC Cardiovascular Disorders 2008 8:35
    Content type: Research article Published on:

  19. Few studies have addressed whether the combined use of B-type natriuretic peptide (BNP) and high-sensitive C-reactive protein (hsCRP) improves risk stratification for mortality and cardiovascular events in a p...

    Authors: Trygve Brügger-Andersen, Volker Pönitz, Harry Staines, David Pritchard, Heidi Grundt and Dennis WT Nilsen
    Citation: BMC Cardiovascular Disorders 2008 8:34
    Content type: Research article Published on:

  20. Most studies documenting beneficial outcomes after carotid endarterectomy (CE) are limited to mortality and morbidity rates, costs, and length of hospital stay (LOS). Few have examined the dependency of patien...

    Authors: Fernando José Abelha, Susana Quevedo and Henrique Barros
    Citation: BMC Cardiovascular Disorders 2008 8:33
    Content type: Research article Published on:

  21. Ruptured abdominal aortic aneurysm (AAA) is responsible for 1–2% of all male deaths over the age of 65 years. Early detection of AAA and elective surgery can reduce the mortality risk associated with AAA. Howe...

    Authors: Lars Ehlers, Jan Sørensen, Lotte Groth Jensen, Merete Bech and Mette Kjølby
    Citation: BMC Cardiovascular Disorders 2008 8:32
    Content type: Research article Published on:

  22. Cardiac pacing is a recognized and widely used treatment for patients presenting with bradycardia. Physicians expect patients to return to normal activities almost immediately post implantation. However, patie...

    Authors: Masooma Aqeel, Azam Shafquat and Nawal Salahuddin
    Citation: BMC Cardiovascular Disorders 2008 8:31
    Content type: Research article Published on:

  23. The reduction of blood pressure alone does not eliminate the increased risk of arterial hypertension. Whilst concomitant metabolic risk factors have been shown to be responsible, the available pharmacotherapy ...

    Authors: Peter Bramlage, Eleonore Schönrock and Peter Odoj
    Citation: BMC Cardiovascular Disorders 2008 8:30
    Content type: Research article Published on:

  24. The Paracetamol (Acetaminophen) In Stroke (PAIS) study is a phase III multicenter, double blind, randomized, placebo-controlled clinical trial of high-dose acetaminophen in patients with acute stroke. The tria...

    Authors: Heleen M den Hertog, H Bart van der Worp, H Maarten A van Gemert, Ale Algra, L Jaap Kappelle, Jan van Gijn, Peter J Koudstaal and Diederik WJ Dippel
    Citation: BMC Cardiovascular Disorders 2008 8:29
    Content type: Erratum Published on:

    The original article was published in BMC Cardiovascular Disorders 2005 5:24

  25. The objective was to explore the relationship between left ventricular ejection fraction (LVEF) assessed during hospitalization for acute myocardial infarction (MI) and later health-related quality of life (HR...

    Authors: Kjell I Pettersen, Elena Kvan, Arnfinn Rollag, Knut Stavem and Aasmund Reikvam
    Citation: BMC Cardiovascular Disorders 2008 8:28
    Content type: Research article Published on:

  26. To establish an efficient prophylaxis of coronary artery disease reliable risk stratification is crucial, especially in the high risk population of patients suffering from diabetes mellitus. This prospective s...

    Authors: Alexander Becker, Alexander W Leber, Christoph Becker, Franz von Ziegler, Janine Tittus, Ines Schroeder, Gerhard Steinbeck and Andreas Knez
    Citation: BMC Cardiovascular Disorders 2008 8:27
    Content type: Research article Published on:

  27. The ankle brachial index (ABI) is a well-established tool for screening and diagnosis of peripheral arterial disease (PAD). In this study we assessed the validity of ABI determination using a pocket Doppler de...

    Authors: Saskia PA Nicolaï, Lotte M Kruidenier, Ellen V Rouwet, Liliane Wetzels-Gulpers, Constantijn AM Rozeman, Martin H Prins and Joep AW Teijink
    Citation: BMC Cardiovascular Disorders 2008 8:26
    Content type: Research article Published on:

  28. Although morbidity and mortality from coronary heart disease (CHD) are high, only a minority of acute coronary syndrome (ACS) survivors accesses an effective secondary prevention program. We aim to determine w...

    Authors: Lis Neubeck, Julie Redfern, Tom Briffa, Adrian Bauman, David Hare and SB Freedman
    Citation: BMC Cardiovascular Disorders 2008 8:25
    Content type: Study protocol Published on:

  29. Experimental and epidemiological evidence suggests that homocysteine (tHcy) may be a causal risk factor for atherosclerosis. B-vitamin supplements reduce tHcy and improve endothelial function in short term tri...

    Authors: Kathleen Potter, Graeme J Hankey, Daniel J Green, John Eikelboom, Konrad Jamrozik and Leonard F Arnolda
    Citation: BMC Cardiovascular Disorders 2008 8:24
    Content type: Research article Published on:

  30. The adverse effects of tobacco abuse on cardiovascular outcomes are well-known. However, the impact of passive smoke exposure on angina status and therapeutic response is less well-established. We examined the...

    Authors: Stilianos Efstratiadis, Elizabeth D Kennard, Sheryl F Kelsey and Andrew D Michaels
    Citation: BMC Cardiovascular Disorders 2008 8:23
    Content type: Research article Published on:

  31. Many patients suffering acute myocardial infarction (AMI) are transferred from one hospital to another during their hospitalization. There is little information about the outcomes related to interhospital tran...

    Authors: John M Westfall, Catarina I Kiefe, Norman W Weissman, Anthony Goudie, Robert M Centor, O Dale Williams and Jeroan J Allison
    Citation: BMC Cardiovascular Disorders 2008 8:22
    Content type: Research article Published on:

  32. Up-regulation of vascular endothelin type B (ETB) receptors is implicated in the pathogenesis of cardiovascular disease. Culture of intact arteries has been shown to induce similar receptor alterations and has th...

    Authors: David Nilsson, Lotta Gustafsson, Angelica Wackenfors, Bodil Gesslein, Lars Edvinsson, Per Paulsson, Richard Ingemansson and Malin Malmsjö
    Citation: BMC Cardiovascular Disorders 2008 8:21
    Content type: Research article Published on:

  33. Recent studies have documented an increased risk of cardiovascular disease (CVD) in persons with systolic blood pressures of 120–139 mmHg and/or diastolic blood pressures of 80–89 mmHg, classified as prehypert...

    Authors: Trevor S Ferguson, Novie OM Younger, Marshall K Tulloch-Reid, Marilyn B Lawrence Wright, Elizabeth M Ward, Deanna E Ashley and Rainford J Wilks
    Citation: BMC Cardiovascular Disorders 2008 8:20
    Content type: Research article Published on:

  34. Ultrasound (US) has been used to enhance thrombolytic therapy in the treatment of stroke. Considerable attenuation of US intensity is however noted if US is applied over the temporal bone. The aim of this stud...

    Authors: Bjarne Madsen Härdig, Jonas Carlson and Anders Roijer
    Citation: BMC Cardiovascular Disorders 2008 8:19
    Content type: Research article Published on:

  35. The ten year probability of cardiovascular events can be calculated, but many people are unaware of their risk and unclear how to reduce it. The aim of this study was to assess whether a community based interv...

    Authors: Gill Richardson, Hugo C van Woerden, Lucy Morgan, Rhiannon Edwards, Monica Harries, Elaine Hancock, Susan Sroczynsk and Mererid Bowley
    Citation: BMC Cardiovascular Disorders 2008 8:18
    Content type: Research article Published on:

  36. The registration of non-fatal and fatal MI events initiated 1985 in the WHO MONICA project has been ongoing in northern Sweden since the end of the WHO project in 1995. The purpose of the present study was to ...

    Authors: Dan Lundblad, Lars Holmgren, Jan-Håkan Jansson, Ulf Näslund and Mats Eliasson
    Citation: BMC Cardiovascular Disorders 2008 8:17
    Content type: Research article Published on:

  37. Heart failure is a major and growing public health problem worldwide. The prognosis of Heart Failure (HF) is uniformly poor despite advances in treatment. The aims of the present study were to determine the ca...

    Authors: Kamilu M Karaye and Mahmoud U Sani
    Citation: BMC Cardiovascular Disorders 2008 8:16
    Content type: Research article Published on:

  38. Several polymorphisms within the renin-angiotensin system cluster of genes have been associated with the advent of coronary artery disease (CAD) or related pathologies. We investigated the distribution of 5 of...

    Authors: Ana I Freitas, Isabel Mendonça, Maria Brión, Miguel M Sequeira, Roberto P Reis, Angel Carracedo and António Brehm
    Citation: BMC Cardiovascular Disorders 2008 8:15
    Content type: Research article Published on:

  39. Topical negative pressure (TNP), widely used in wound therapy, is known to stimulate wound edge blood flow, granulation tissue formation, angiogenesis, and revascularization. We have previously shown that appl...

    Authors: Sandra Lindstedt, Per Paulsson, Arash Mokhtari, Bodil Gesslein, Joanna Hlebowicz, Malin Malmsjö and Richard Ingemansson
    Citation: BMC Cardiovascular Disorders 2008 8:14
    Content type: Research article Published on:

  40. Non-pharmacological treatment options for hypertension have the potential to reduce the risk of cardiovascular disease at a population level. Animal studies have suggested that garlic reduces blood pressure, b...

    Authors: Karin Ried, Oliver R Frank, Nigel P Stocks, Peter Fakler and Thomas Sullivan
    Citation: BMC Cardiovascular Disorders 2008 8:13
    Content type: Research article Published on:

  41. The metabolic syndrome (Msyn) affects about 40% of those with hypertension. The Msyn and hypertension have a common pathophysiology. Exercise is recommended for their treatment, prevention and control. The inf...

    Authors: Linda S Pescatello, Bruce E Blanchard, Jaci L Van Heest, Carl M Maresh, Heather Gordish-Dressman and Paul D Thompson
    Citation: BMC Cardiovascular Disorders 2008 8:12
    Content type: Research article Published on:

  42. Acute vigorous exercise, associated with increased release of plasma catecholamines, transiently increases the risk of primary cardiac arrest. We tested the effect of acute submaximal exercise on vasoactive su...

    Authors: Konstantinos Petidis, Stella Douma, Michael Doumas, Ilias Basagiannis, Konstantinos Vogiatzis and Chrysanthos Zamboulis
    Citation: BMC Cardiovascular Disorders 2008 8:11
    Content type: Research article Published on:

  43. In Shanghai there are 1.2 million people with hypertension, many of whom have difficulty in affording medical treatment. Community based, anti-hypertensive clubs have been created to provide health education b...

    Authors: Feng Xue, Wen Yao and Robert J Lewin
    Citation: BMC Cardiovascular Disorders 2008 8:10
    Content type: Research article Published on:

  44. Hypoxia inducible factor-1 (HIF-1) is a transcription factor that functions to maintain cellular homeostasis in response to hypoxia. There is evidence that HIF-1 can also trigger apoptosis, possibly when cellu...

    Authors: Ricky Malhotra, David W Tyson, Henry M Rosevear and Frank C Brosius III
    Citation: BMC Cardiovascular Disorders 2008 8:9
    Content type: Research article Published on:

  45. Currently used biomarkers for cardiac ischemia are elevated in blood plasma after a delay of several hours and therefore unable to detect acute coronary syndrome (ACS) in a very early stage. General practition...

    Authors: Madeleine HE Bruins Slot, Geert JMG van der Heijden, Frans H Rutten, Onno P van der Spoel, E Gijs Mast, Ad C Bredero, Pieter A Doevendans, Jan FC Glatz and Arno W Hoes
    Citation: BMC Cardiovascular Disorders 2008 8:8
    Content type: Study protocol Published on:

  46. The aim of this study was to evaluate the combination of a rapid intravenous infusion of cold saline and endovascular hypothermia in a closed chest pig infarct model.

    Authors: Matthias Götberg, Goran K Olivecrona, Henrik Engblom, Martin Ugander, Jesper van der Pals, Einar Heiberg, Håkan Arheden and David Erlinge
    Citation: BMC Cardiovascular Disorders 2008 8:7
    Content type: Research article Published on:

  47. Cardiovascular diseases and their associated risk factors remain the main cause of mortality in western societies. In order to assess the prevalence of cardiovascular risk factors (CVRFs) in the Caucasian popu...

    Authors: Mathieu Firmann, Vladimir Mayor, Pedro Marques Vidal, Murielle Bochud, Alain Pécoud, Daniel Hayoz, Fred Paccaud, Martin Preisig, Kijoung S Song, Xin Yuan, Theodore M Danoff, Heide A Stirnadel, Dawn Waterworth, Vincent Mooser, Gérard Waeber and Peter Vollenweider
    Citation: BMC Cardiovascular Disorders 2008 8:6
    Content type: Research article Published on:

  48. Recessive mutations in WRN gene eliminate WRN protein function (helicase) and cause Werner syndrome. One of the most important clinical features of Werner syndrome patients are the premature onset and accelerated...

    Authors: Elena Castro, Vladimir Oviedo-Rodríguez and Luis I Angel-Chávez
    Citation: BMC Cardiovascular Disorders 2008 8:5
    Content type: Research article Published on:

  49. In the present study we sought to determine the long-term prognostic value of left ventricular ejection fraction (LVEF), assessed by planar radionuclide ventriculography (PRV), after ST-elevation myocardial in...

    Authors: Pieter A van der Vleuten, Saman Rasoul, Willem Huurnink, Iwan CC van der Horst, Riemer HJA Slart, Stoffer Reiffers, Rudi A Dierckx, René A Tio, Jan Paul Ottervanger, Menko-Jan De Boer and Felix Zijlstra
    Citation: BMC Cardiovascular Disorders 2008 8:4
    Content type: Research article Published on:
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BMC Cardiovascular Disorders

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