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  1. Since its first description, Mönckeberg's sclerosis has only been related to arterial media calcification, being listed among the primary diseases of the vessels.

    Authors: Carlos Eduardo Barra Couri, Geruza Alves da Silva, José Antônio Baddini Martinez, Francisco de Assis Pereira and Francisco José Albuquerque de Paula
    Citation: BMC Cardiovascular Disorders 2005 5:34
  2. The increasing burden of cardiovascular diseases (CVD) in the ageing population of industrialized nations requires an intensive search for means of reducing this epidemic. In order to improve prevention, detec...

    Authors: Karin H Greiser, Alexander Kluttig, Barbara Schumann, Jan A Kors, Cees A Swenne, Oliver Kuss, Karl Werdan and Johannes Haerting
    Citation: BMC Cardiovascular Disorders 2005 5:33
  3. Microsomal transfer protein inhibitors (MTPi) have the potential to be used as a drug to lower plasma lipids, mainly plasma triglycerides (TG). However, studies with animal models have indicated that MTPi trea...

    Authors: Dimple Aggarwal, Kristy L West, Tosca L Zern, Sudeep Shrestha, Marcela Vergara-Jimenez and Maria Luz Fernandez
    Citation: BMC Cardiovascular Disorders 2005 5:30
  4. Accurate measurement of the QT interval is very important from a clinical and pharmaceutical drug safety screening perspective. Expert manual measurement is both imprecise and imperfectly reproducible, yet it ...

    Authors: Anthony Charles Hunt
    Citation: BMC Cardiovascular Disorders 2005 5:29
  5. Experimental studies support an important role for endothelial nitric oxide synthase (eNOS) in the regulation of angiogenesis. In humans, a common polymorphism exists in the eNOS gene that results in the conve...

    Authors: Nicolas Lamblin, François J Cuilleret, Nicole Helbecque, Jean Dallongeville, Jean-Marc Lablanche, Philippe Amouyel, Christophe Bauters and Eric Van Belle
    Citation: BMC Cardiovascular Disorders 2005 5:27
  6. Body mass index (BMI, kg/m2) may not be the best marker for estimating the risk of obesity-related disease. Consistent with physiologic observations, an alternative index uses waist circumference (WC) and fasting...

    Authors: Henry S Kahn
    Citation: BMC Cardiovascular Disorders 2005 5:26

    The Erratum to this article has been published in BMC Cardiovascular Disorders 2006 6:5

  7. The protective role of high-density lipoprotein (HDL) in the cardiovascular system is related to its role in the reverse transport of cholesterol from the arterial wall to the liver for subsequent excretion vi...

    Authors: Per-Arne Svensson, Mikael CO Englund, Magnus SC Snäckestrand, Daniel A Hägg, Bertil G Ohlsson, Veronika Stemme, Lillemor Mattsson-Hulten, Dag S Thelle, Björn Fagerberg, Olov Wiklund, Lena MS Carlsson and Björn Carlsson
    Citation: BMC Cardiovascular Disorders 2005 5:25
  8. In patients with acute stroke, increased body temperature is associated with large lesion volumes, high case fatality, and poor functional outcome. A 1°C increase in body temperature may double the odds of poo...

    Authors: Eric J van Breda, H Bart van der Worp, H Maarten A van Gemert, Ale Algra, L Jaap Kappelle, Jan van Gijn, Peter J Koudstaal and Diederik WJ Dippel
    Citation: BMC Cardiovascular Disorders 2005 5:24

    The Erratum to this article has been published in BMC Cardiovascular Disorders 2008 8:29

  9. Sirolimus-eluting stents (CYPHER stents) demonstrated remarkable efficacy in reducing restenosis rates in patients with coronary artery disease. There is a concern of sub-acute and late stent thrombosis. Tissu...

    Authors: Shengsi Zhu, Hema Viswambharan, Thusitha Gajanayake, Xiu-Fen Ming and Zhihong Yang
    Citation: BMC Cardiovascular Disorders 2005 5:22
  10. Regional disparities in medical care and outcomes with patients suffering from an acute coronary syndrome (ACS) have been reported and raise the need to a better understanding of links between treatment, care ...

    Authors: Alain Vanasse, Théophile Niyonsenga, Josiane Courteau, Jean-Pierre Grégoire, Abbas Hemiari, Julie Loslier and Goze Bénié
    Citation: BMC Cardiovascular Disorders 2005 5:21
  11. Natural history of paroxysmal atrial fibrillation (AF) is not very well documented. Clinical experience suggests that paroxysmal AF could progress to chronic AF with estimates ranging between 15 and 30% over a...

    Authors: Ana Ruigómez, Saga Johansson, Mari-Ann Wallander and Luis Alberto García Rodríguez
    Citation: BMC Cardiovascular Disorders 2005 5:20
  12. Aprotinin has been shown to be effective in reducing peri-operative blood loss and the need for re-operation due to continued bleeding in cardiac surgery. The lysine analogues tranexamic acid (TXA) and epsilon...

    Authors: Paul A Carless, Annette J Moxey, Barrie J Stokes and David A Henry
    Citation: BMC Cardiovascular Disorders 2005 5:19
  13. Increasing evidence suggests that ABPM more closely predicts target organ damage than does clinic measurement. Future guidelines may suggest ABPM as routine in the diagnosis and monitoring of hypertension. Thi...

    Authors: Linda Beckett and Marshall Godwin
    Citation: BMC Cardiovascular Disorders 2005 5:18
  14. Although much has been written about the influence of local opinion leaders on clinical practice, there have been few controlled studies of their effect, and almost none have attempted to change prescribing in...

    Authors: Sumit R Majumdar, Finlay A McAlister and Ross T Tsuyuki
    Citation: BMC Cardiovascular Disorders 2005 5:17
  15. Prior literature has shown that racial/ethnic minorities with hypertension may receive less aggressive treatment for their high blood pressure. However, to date there are few data available regarding the confo...

    Authors: LeRoi S Hicks, Shimon Shaykevich, David W Bates and John Z Ayanian
    Citation: BMC Cardiovascular Disorders 2005 5:16
  16. Awareness of the significance of peripheral arterial disease is increasing, but quantitative estimates of the ensuing burden and the impact of other risk factors remains limited. The objective of this study wa...

    Authors: Jaime Caro, Kristen Migliaccio-Walle, Khajak J Ishak and Irina Proskorovsky
    Citation: BMC Cardiovascular Disorders 2005 5:14
  17. Persistence is a key factor for long-term blood pressure control, which is of high prognostic importance for patients at increased cardiovascular risk. Here we present the results of a post-marketing survey in...

    Authors: Michel Burnier, Bernhard Hess, Peter Greminger and Bernard Waeber
    Citation: BMC Cardiovascular Disorders 2005 5:13
  18. Chronic inflammatory stimuli such as cytomegalovirus (CMV) infection and various genetic polymorphisms determining the inflammatory response are assumed to be important risk factors in atherosclerosis. We inve...

    Authors: Dietrich Rothenbacher, Hermann Brenner, Thomas Mertens, Michael M Hoffmann, Albrecht Hoffmeister and Wolfgang Koenig
    Citation: BMC Cardiovascular Disorders 2005 5:10
  19. Mycophenolate mofetil (MMF), the prodrug of mycophenolic acid (MPA), is a rationally designed immunosuppressive drug. The current study investigates the effect of MMF on key pattern of restenosis in a cascade ...

    Authors: Rainer Voisard, Sandra Viola, Verena Kaspar, Christian M Weber, Lutz von Müller, Regine Baur, Iris Gastrock-Balitsch and Vinzenz Hombach
    Citation: BMC Cardiovascular Disorders 2005 5:9
  20. The same mechanisms by which ultrasound enhances thrombolysis are described in connection with non-beneficial effects of ultrasound. The present safety study was therefore designed to explore effects of benefi...

    Authors: Göran K Olivecrona, Bjarne Madsen Härdig, Anders Roijer, Mattias Block, Edgars Grins, Hans W Persson, Leif Johansson and Bertil Olsson
    Citation: BMC Cardiovascular Disorders 2005 5:8
  21. Essential hypertension is a major public health concern worldwide where its prevalence accounts for various cerebrovascular diseases. A common molecular variant of angiotensinogen (AGT), the precursor of poten...

    Authors: Yee-How Say, King-Hwa Ling, Gnanasothie Duraisamy, Suzanne Isaac and Rozita Rosli
    Citation: BMC Cardiovascular Disorders 2005 5:7
  22. Acute myocardial infarction (MI) following anaphylaxis is rare, especially in subjects with normal coronary arteries. The exact pathogenetic mechanism of MI in anaphylaxis remains unclear.

    Authors: Aristofanis Gikas, George Lazaros and Kalliopi Kontou-Fili
    Citation: BMC Cardiovascular Disorders 2005 5:6
  23. Shorter time to treatment is associated with lower mortality in acute coronary syndromes (ACS). A previous (1994) survey showed substantial delays for acute myocardial infarction (AMI) in Ireland. The present ...

    Authors: Frank Doyle, Davida De La Harpe, Hannah McGee, Emer Shelley and Ronán Conroy
    Citation: BMC Cardiovascular Disorders 2005 5:5
  24. Lack of antihypertensive use among hypertensive individuals is a major public health problem. It remains unclear as to how much of this lack of treatment is because of failure to diagnose hypertension or failu...

    Authors: Nadia A Khan, Dennis Wardman and Norman RC Campbell
    Citation: BMC Cardiovascular Disorders 2005 5:4
  25. Persistent atrial fibrillation (AF) is difficult to treat. In the absence of class I or III antiarrhythmic drugs sinus rhythm is maintained in only 30% of patients during the first year after electrical cardio...

    Authors: Trudeke Van Noord, Harry JGM Crijns, Maarten P van den Berg, Dirk J Van Veldhuisen and Isabelle C Van Gelder
    Citation: BMC Cardiovascular Disorders 2005 5:3
  26. Although current evidence suggests that the spatial T wave axis captures important information about ventricular repolarization abnormalities, there are only a few and discordant epidemiologic studies addressi...

    Authors: Georgeta D Vaidean, Pentti M Rautaharju, Ronald J Prineas, Eric A Whitsel, Lloyd E Chambless, Aaron R Folsom, Wayne D Rosamond, Zhu-Ming Zhang, Richard S Crow and Gerardo Heiss
    Citation: BMC Cardiovascular Disorders 2005 5:2
  27. Despite heavy recent emphasis on blood pressure (BP) control, many patients fail to meet widely accepted goals. While access and adherence to therapy certainly play a role, another potential explanation is poo...

    Authors: Steven M Asch, Elizabeth A McGlynn, Liisa Hiatt, John Adams, Jennifer Hicks, Alison DeCristofaro, Roland Chen, Pablo LaPuerta and Eve A Kerr
    Citation: BMC Cardiovascular Disorders 2005 5:1
  28. To evaluate current treatment patterns for coronary artery revascularization in Canada and explore the potential impact of drug eluting stents (DES) on these treatment patterns.

    Authors: Michael T Halpern, Michael Lacey, Mary Ann Clark and Miguel A Valentin
    Citation: BMC Cardiovascular Disorders 2004 4:23
  29. Intra-aortic balloon counterpulsation (IABC) has an established role in the treatment of patients presenting with critical cardiac illnesses, including cardiogenic shock, refractory ischemia and for prophylaxi...

    Authors: Fahim H Jafary, Sohail A Khan, Haresh Kumar, Numaan F Malik, Khawar A Kazmi, Sajid Dhakam, Azam Shafquat, Aamir Hameed, Javed Tai and Najaf Nadeem
    Citation: BMC Cardiovascular Disorders 2004 4:22
  30. Coronary artery calcium score incrementally improves coronary risk prediction beyond that provided by conventional risk factors. Limited information is available regarding rates of progression of coronary calc...

    Authors: Judith Hsia, Afifa Klouj, Anjana Prasad, Jeremy Burt, Lucile L Adams-Campbell and Barbara V Howard
    Citation: BMC Cardiovascular Disorders 2004 4:21
  31. Certain conditions characterised by blood vessel occlusion or vascular spasm have been found to cluster together in epidemiological studies. However the biological causes for these associations remain controve...

    Authors: Frances MK Williams, Lynn F Cherkas, Tim D Spector and Alex J MacGregor
    Citation: BMC Cardiovascular Disorders 2004 4:20
  32. Warfarin therapy is effective for the prevention of stroke in patients with atrial fibrillation. However, warfarin therapy is underutilized even among ideal anticoagulation candidates. The purpose of this stud...

    Authors: Dawn M Bravata, Karen Rosenbeck, Sue Kancir and Lawrence M Brass
    Citation: BMC Cardiovascular Disorders 2004 4:18
  33. Plasma levels of tumor necrosis factor (TNF)-α and of C-reactive protein (CRP) are elevated in smokers. Previous studies failed to show an association between the G-308A polymorphism in the promoter region of ...

    Authors: Marie-Louise Gander, Joachim E Fischer, Friedrich E Maly and Roland von Känel
    Citation: BMC Cardiovascular Disorders 2004 4:17
  34. Dyslipidemia has been associated with hypertension. The present study explored if polymorphisms in genes encoding proteins in lipid metabolism could be used as predictors for the individual response to antihyp...

    Authors: Ulrika Liljedahl, Lars Lind, Lisa Kurland, Lars Berglund, Thomas Kahan and Ann-Christine Syvänen
    Citation: BMC Cardiovascular Disorders 2004 4:16
  35. Individuals with coronary artery disease are at high risk for adverse health outcomes. This risk can be diminished by aggressive lipid management, but adherence to lipid management guidelines is far from ideal...

    Authors: Mark W Massing, Kathleen A Foley, Lori Carter-Edwards, Carla A Sueta, Charles M Alexander and Ross J Simpson Jr
    Citation: BMC Cardiovascular Disorders 2004 4:15
  36. The management of acute myocardial infarction (AMI) has improved over the last 50 years with the more frequent use of effective medicines and procedures. The clinical benefit of the speciality of the attending...

    Authors: Ibrahim Abubakar, David Kanka, Barbara Arch, Jo Porter and Peter Weissberg
    Citation: BMC Cardiovascular Disorders 2004 4:14
  37. Surprisingly little information on symptoms of paroxysmal atrial fibrillation is available in scientific literature. Using questionnaires, we have analyzed the symptoms associated with arrhythmia attacks.

    Authors: Anders Hansson, Bjarne Madsen-Härdig and S Bertil Olsson
    Citation: BMC Cardiovascular Disorders 2004 4:13
  38. Atrial fibrillation (AF) has been recognised as an important independent risk factor for thromboembolic disease, particularly stroke for which it provides a five-fold increase in risk. This study aimed to dete...

    Authors: Dawn Swancutt, Richard Hobbs, David Fitzmaurice, Jonathan Mant, Ellen Murray, Sue Jowett, James Raftery, Stirling Bryan, Michael Davies and Gregory Lip
    Citation: BMC Cardiovascular Disorders 2004 4:12
  39. Despite improvements in the safety and efficacy of endovascular procedures, considerable morbidity may still be attributed to vasospasm. Vasospasm has proven amenable to pharmacological intervention such as ni...

    Authors: Alexander L Coon, Geoffrey P Colby, William J Mack, Lei Feng, Philip Meyers and E Sander Connolly Jr
    Citation: BMC Cardiovascular Disorders 2004 4:11
  40. Local ventricular refractoriness and its dispersion during ventricular fibrillation (VF) have not been well evaluated, due to methodological difficulties.

    Authors: Jijian Luo, Carl Magnus Pripp, Eva Hertervig, Ole Kongstad, Erik Ljungström, S Bertil Olsson and Shiwen Yuan
    Citation: BMC Cardiovascular Disorders 2004 4:8

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