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  1. The use of inappropriate elective Percutaneous Coronary Intervention (PCI) has decreased over time, but hospital-level variation in the use of inappropriate PCI persists. Understanding the barriers and facilit...

    Authors: Anne Lambert-Kerzner, Charles Maynard, Marina McCreight, Amy Ladebue, Katherine M. Williams, Kelty B. Fehling and Steven M. Bradley
    Citation: BMC Cardiovascular Disorders 2018 18:164
    Content type: Research article Published on:

  2. This study aimed to evaluate cost-utility of baroreflex activation therapy (BAT) using the Barostim neo™ device (CVRx Inc., Minneapolis, MN, USA) compared with optimized medical management in patients with advanc...

    Authors: Oleg Borisenko, Jochen Müller-Ehmsen, JoAnn Lindenfeld, Erik Rafflenbeul and Christian Hamm
    Citation: BMC Cardiovascular Disorders 2018 18:163
    Content type: Research article Published on:

  3. Left ventricular (LV) hypertrophy and changes in LV geometry are associated with increased cardiovascular mortality. Subjects with type 2 diabetes have an increased risk of such alterations in cardiac morpholo...

    Authors: Susanne Rospleszcz, Anina Schafnitzel, Wolfgang Koenig, Roberto Lorbeer, Sigrid Auweter, Cornelia Huth, Wolfgang Rathmann, Margit Heier, Birgit Linkohr, Christa Meisinger, Holger Hetterich, Fabian Bamberg and Annette Peters
    Citation: BMC Cardiovascular Disorders 2018 18:162
    Content type: Research article Published on:

  4. Adaptor-related protein complex 2 alpha 2 subunit (AP2A2) gene encodes a protein-a subunit of the AP-2 adaptor protein complex. Evidence has revealed that benzodiazepine receptor-associated protein 1 (BZRAP1) ...

    Authors: Sibo Wang, Zhihui Ma, Yongjun Zhang, Yankui Ding, Zhong Chen and Liansheng Wang
    Citation: BMC Cardiovascular Disorders 2018 18:161
    Content type: Research article Published on:

  5. Understanding the determinants associated with prediabetes and type 2 diabetes in coronary patients may help to individualize treatment and modelling interventions. We sought to identify sociodemographic, medi...

    Authors: John Munkhaugen, Jøran Hjelmesæth, Jan Erik Otterstad, Ragnhild Helseth, Stina Therese Sollid, Erik Gjertsen, Lars Gullestad, Joep Perk, Torbjørn Moum, Einar Husebye and Toril Dammen
    Citation: BMC Cardiovascular Disorders 2018 18:160
    Content type: Research article Published on:

  6. Heart failure (HF) and frailty often co-exist, and frailty in HF results in a poor prognosis. However, in Asian populations, prognostic criteria are needed to examine the effect of frailty on HF. Therefore, we...

    Authors: Sumio Yamada, Takuji Adachi, Hideo Izawa, Toyoaki Murohara and Takaaki Kondo
    Citation: BMC Cardiovascular Disorders 2018 18:159
    Content type: Study protocol Published on:

  7. Hypertensive crises are clinical syndromes grouped as hypertensive urgency and emergency, which occur as complications of untreated or inadequately treated hypertension. Emergency departments across the world ...

    Authors: Patrick J. Shao, Hendry R. Sawe, Brittany L. Murray, Juma A. Mfinanga, Victor Mwafongo and Michael S. Runyon
    Citation: BMC Cardiovascular Disorders 2018 18:158
    Content type: Research article Published on:

  8. The aim of the study was to investigate the high-sensitivity troponin T (hs-TnT) release profile in off-pump coronary artery bypass grafting (OPCABG) patients with normal postoperative course.

    Authors: Wen Ge, Chang Gu, Chao Chen, Wangwang Chen, Zhengqiang Cang, Yuliang Wang, Chennan Shi and Yangyang Zhang
    Citation: BMC Cardiovascular Disorders 2018 18:157
    Content type: Research article Published on:

  9. Angina pectoris (AP) and unheralded myocardial infarction (MI) are considered random clinical equivalents of ischemic heart disease (IHD). Aim of the study was to evaluate the long-term progression of AP as op...

    Authors: Clara Carpeggiani, Claudio Michelassi, Patrizia Landi and Antonio L’Abbate
    Citation: BMC Cardiovascular Disorders 2018 18:156
    Content type: Research article Published on:

  10. Recent clinical trials have shown that pulmonary artery pressure-guided therapy via the CardioMEMS™ system reduces the risk of recurrent hospitalizations in chronic heart failure (HF) patients. The CardioMEMS™...

    Authors: Carsten Tschöpe, Alessio Alogna, Frank Spillmann, Alessandro Faragli, Gunther Schmidt, Florian Blaschke, Uwe Kühl, Ewa Hertel, Monika Willner, Daniel Morris, Heiner Post, Michel Noutsias, Burkert Pieske and Florian Krackhardt
    Citation: BMC Cardiovascular Disorders 2018 18:155
    Content type: Case report Published on:

  11. The stress in the ascending aorta results from many biomechanical factors including the geometry of the vessel and its maximum dimensions, arterial blood pressure and longitudinal systolic stretching due to he...

    Authors: Tomasz Plonek, Mikolaj Berezowski, Jacek Kurcz, Przemyslaw Podgorski, Marek Sąsiadek, Bartosz Rylski, Andrzej Mysiak and Marek Jasinski
    Citation: BMC Cardiovascular Disorders 2018 18:154
    Content type: Research article Published on:

  12. Left atrial appendage morphology has been proved to be an important predictor of left atrial thrombus (LAT) and left atrial spontaneous echo contrast (LASEC) and stroke in patients with non-valvular atrial fib...

    Authors: Fan Wang, Mengyun Zhu, Xiaoyu Wang, Wei Zhang, Yang Su, Yuyan Lu, Xin Pan, Di Gao, Xianling Zhang, Wei Chen, Yawei Xu, Yuxi Sun and Dachun Xu
    Citation: BMC Cardiovascular Disorders 2018 18:153
    Content type: Research article Published on:

  13. Lipomatous hypertrophy of the atrial septum (LHAS) is an anomaly of the heart. It is characterized by an infiltration of adipocytes into myocytes of the interatrial septum, sparing the fossa ovalis, which give...

    Authors: Grzegorz Bielicki, Marceli Lukaszewski, Kinga Kosiorowska, Jacek Jakubaszko, Rafal Nowicki and Marek Jasinski
    Citation: BMC Cardiovascular Disorders 2018 18:152
    Content type: Case report Published on:

  14. Ischemic Heart Disease (IHD) is the first ranked among most common causes of death involving cardiovascular and other diseases. The information on the prevalence of IHD in Thailand is lacking especially among ...

    Authors: Boonsub Sakboonyarat and Ram Rangsin
    Citation: BMC Cardiovascular Disorders 2018 18:151
    Content type: Research article Published on:

  15. Hypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours dise...

    Authors: Nkengla Menka Adidja, Valirie Ndip Agbor, Jeannine A. Aminde, Calypse A. Ngwasiri, Kathleen Blackett Ngu and Leopold Ndemnge Aminde
    Citation: BMC Cardiovascular Disorders 2018 18:150
    Content type: Research article Published on:

  17. In patients with Noonan syndrome (NS), cardiac disorders such as pulmonary valve stenosis (PS) or hypertrophic cardiomyopathy (HCM) are common. While some patients can develop heart failure associated with HCM...

    Authors: Yoshito Kadoya, Tsuneaki Kenzaka, Yohei Oda and Satoaki Matoba
    Citation: BMC Cardiovascular Disorders 2018 18:148
    Content type: Case report Published on:

  18. Nonalcoholic fatty liver disease (NAFLD) refers to fatty infiltration of liver in the absence of excessive alcohol abuse. However, the problem that whether NAFLD is correlated with subclinical atherosclerosis ...

    Authors: Jilin Zheng, Yong Zhou, Kuo Zhang, Yu Qi, Shimin An, Siyuan Wang, Xingquan Zhao and Yi-Da Tang
    Citation: BMC Cardiovascular Disorders 2018 18:147
    Content type: Research article Published on:

  19. It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in p...

    Authors: M. Skowerski, I. Wozniak-Skowerska, A. Hoffmann, S. Nowak, T. Skowerski, M. Sosnowski, A. M. Wnuk-Wojnar and K. Mizia-Stec
    Citation: BMC Cardiovascular Disorders 2018 18:146
    Content type: Research article Published on:

  20. Extent of myocardial fibrosis (MF) determined using late gadolinium enhanced (LGE) predicts outcomes, but gadolinium is contraindicated in advanced renal disease. We assessed the ability of native T1-mapping t...

    Authors: M. P. Graham-Brown, A. S. Singh, G. S. Gulsin, E. Levelt, J. A. Arnold, D. J. Stensel, J. O. Burton and G. P. McCann
    Citation: BMC Cardiovascular Disorders 2018 18:145
    Content type: Research article Published on:

  21. The potential life-threatening consequences of catecholamine use for emergency circulatory support in Takotsubo cardiomyopathy-related acute heart failure is a major challenge in cardiovascular emergences. In ...

    Authors: Michael Dandel and Roland Hetzer
    Citation: BMC Cardiovascular Disorders 2018 18:144
    Content type: Correspondence Published on:

  22. The xanthine oxidase inhibitor allopurinol that is commonly used to treat gout, has been suggested to have pleiotropic effects that are likely to reduce the incidence of myocardial infarction (MI) in at risk i...

    Authors: Tejas P. Singh, Tristan Skalina, Daniel Nour, Aarya Murali, Sean Morrison, Joseph V. Moxon and Jonathan Golledge
    Citation: BMC Cardiovascular Disorders 2018 18:143
    Content type: Research article Published on:

  23. Intracardiac invasion of head and neck cancer is extremely rare. Here, we report a case of recurred oral cavity cancer presenting with complete atrioventricular (AV) block caused by cardiac metastasis.

    Authors: Jae Yeong Cho, Kye Hun Kim, Hyukjin Park, Hyun Ju Yoon and Jong Chun Park
    Citation: BMC Cardiovascular Disorders 2018 18:142
    Content type: Case report Published on:

  24. Inflammation is a common feature of both peripheral arterial disease (PAD) and periodontitis. Some studies have evaluated the association between PAD and periodontitis. However, there is still no specialized m...

    Authors: Shuo Yang, Li Sheng Zhao, Chuan Cai, Quan Shi, Ning Wen and Juan Xu
    Citation: BMC Cardiovascular Disorders 2018 18:141
    Content type: Research article Published on:

  25. The cardiovascular disease risk was assessed in metabolically healthy obese (MHO) children, obese children with metabolic disorders (MUO), and to a control group of normal-weight children using carotid intima-...

    Authors: Giovanni Farello, Annarita Antenucci, Stefano Stagi, Chiara Mazzocchetti, Franco Ciocca and Alberto Verrotti
    Citation: BMC Cardiovascular Disorders 2018 18:140
    Content type: Research article Published on:

  26. The EPICOR Asia (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) study (NCT01361386) was an observational study of patients hospitalized for acute coronar...

    Authors: Stephen Jan, Stephen W-L. Lee, Jitendra P. S. Sawhney, Tiong K. Ong, Chee Tang Chin, Hyo-Soo Kim, Rungroj Krittayaphong, Vo T. Nhan, Stuart J. Pocock, Ana M. Vega, Nobuya Hayashi and Yong Huo
    Citation: BMC Cardiovascular Disorders 2018 18:139
    Content type: Research article Published on:

  27. Despite marked advances in our understanding of the pathophysiology of the coronary slow flow phenomenon (CSFP), the exact mechanism remains unclear. Previous studies have suggested that CSFP might be associat...

    Authors: Yong Wang, Mou-jie Liu, Hui-min Yang, Chun-yan Ma, Peng-yu Jia, Da-lin Jia and Ai-jie Hou
    Citation: BMC Cardiovascular Disorders 2018 18:138
    Content type: Research article Published on:

  29. In Denmark and other countries, there has been a shift in the management of patients with an implantable cardioverter defibrillator (ICD) with remote device monitoring largely replacing in-hospital visits. Les...

    Authors: Susanne S. Pedersen, Søren J. Skovbakke, Uffe K. Wiil, Thomas Schmidt, Rene dePont Christensen, Carl J. Brandt, Jan Sørensen, Michael Vinther, Charlotte E. Larroudé, Thomas M. Melchior, Sam Riahi, Kim G. E. Smolderen, John A. Spertus, Jens B. Johansen and Jens C. Nielsen
    Citation: BMC Cardiovascular Disorders 2018 18:136
    Content type: Study protocol Published on:

  30. The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research component of a broad program aimed at primary and s...

    Authors: John Musuku, Mark E. Engel, Patrick Musonda, Joyce Chipili Lungu, Elizabeth Machila, Sherri Schwaninger, Agnes Mtaja, Evans Mulendele, Dorothy Kavindele, Jonathan Spector, Brigitta Tadmor, Marcelo M. Gutierrez, Joris Van Dam, Laurence Colin, Aidan Long, Mark C. Fishman…
    Citation: BMC Cardiovascular Disorders 2018 18:135
    Content type: Research article Published on:

  31. Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop into chronic myocarditis and dilated cardiomyopathy in some patients. We report a case of vir...

    Authors: Tetsuya Yamamoto, Tsuneaki Kenzaka, Masanori Matsumoto, Ryo Nishio, Satoru Kawasaki and Hozuka Akita
    Citation: BMC Cardiovascular Disorders 2018 18:134
    Content type: Case report Published on:

  32. To explore the effects of chronic intermittent hypoxia (CIH), which mimics sleep apnea syndrome, on the cardiac renin angiotensin system (RAS), and to investigate the cardiac protection of an angiotensin recep...

    Authors: Wanyu Wang, Ailing Song, Yiming Zeng, Xiaoyang Chen, Yixiang Zhang, Yonghong Shi, Yihua Lin and Wen Luo
    Citation: BMC Cardiovascular Disorders 2018 18:133
    Content type: Research article Published on:

  33. The stenosis of the coronary arteries is usually caused by atherosclerosis. Hemodynamic significance of patient-specific coronary stenoses and the risk of its progression may be assessed by comparing the hemod...

    Authors: Zbigniew Malota, Jan Glowacki, Wojciech Sadowski and Marcin Kostur
    Citation: BMC Cardiovascular Disorders 2018 18:132
    Content type: Research article Published on:

  34. In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferio...

    Authors: Claudius Hansen, Christian Loges, Karlheinz Seidl, Frank Eberhardt, Herbert Tröster, Krum Petrov, Gerian Grönefeld, Peter Bramlage, Frank Birkenhauer and Christian Weiss
    Citation: BMC Cardiovascular Disorders 2018 18:131
    Content type: Research article Published on:

  35. Nonculprit lesions are the major cause of future cardiovascular events. However, the natural course of nonculprit lesions and angiographic predictors of plaque progression are not well-studied. The purpose of ...

    Authors: Jeehoon Kang, Kyung Woo Park, Michael S. Lee, Chengbin Zheng, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo and Hyo-Soo Kim
    Citation: BMC Cardiovascular Disorders 2018 18:130
    Content type: Research article Published on:

  36. Atrial and ventricular cardiac arrhythmias are one of the most common early complications after cardiac surgery and these serve as a major cause of mortality and morbidity after cardiac revascularization. We w...

    Authors: Shirvan Salaminia, Fatemeh Sayehmiri, Parvin Angha, Koroush Sayehmiri and Morteza Motedayen
    Citation: BMC Cardiovascular Disorders 2018 18:129
    Content type: Research article Published on:

  37. Heart failure (HF) with preserved ejection fraction (HFpEF) comprises nearly half of prevalent HF, yet is challenging to curate in a large database of electronic medical records (EMR) since it requires both ac...

    Authors: Yash R. Patel, Jeremy M. Robbins, Katherine E. Kurgansky, Tasnim Imran, Ariela R. Orkaby, Robert R. McLean, Yuk-Lam Ho, Kelly Cho, J. Michael Gaziano, Luc Djousse, David R. Gagnon and Jacob Joseph
    Citation: BMC Cardiovascular Disorders 2018 18:128
    Content type: Research article Published on:

  38. A previous retrospective cohort study established the relationship between perioperative atrial fibrillation (POAF) and subsequent mortality and stroke. However, the details regarding the cause of death and et...

    Authors: Satoshi Higuchi, Yusuke Kabeya, Kenichi Matsushita, Keisei Tachibana, Riken Kawachi, Hidefumi Takei, Yutaka Suzuki, Nobutsugu Abe, Yorihisa Imanishi, Kiyoshi Moriyama, Tomoko Yorozu, Koichiro Saito, Masanori Sugiyama, Haruhiko Kondo and Hideaki Yoshino
    Citation: BMC Cardiovascular Disorders 2018 18:127
    Content type: Study protocol Published on:

  39. The incidence and mortality of cardiovascular diseases (CVDs) in low and middle income countries (LMICs) have been increasing, while access to CVDs medicines is suboptimal. We assessed selection of essential m...

    Authors: Y. T. Bazargani, M. Ugurlu, A. de Boer, H. G. M. Leufkens and A. K. Mantel-Teeuwisse
    Citation: BMC Cardiovascular Disorders 2018 18:126
    Content type: Research article Published on:

  40. Spontaneous reperfusion (SR) and early infarct related artery (IRA) patency before primary percutaneous coronary intervention (PPCI) might bring extra benefit for patients with ST-segment elevation myocardial ...

    Authors: Jing Li, Ying Zhou, Yaowen Zhang and Jingang Zheng
    Citation: BMC Cardiovascular Disorders 2018 18:125
    Content type: Research article Published on:

  41. Coarctation of aorta (CoA) may progressively develop aortic dilation at other site of the aorta and can lead to fatal aortic diseases. We aimed to evaluate the occurrence of aortic dilation and related predict...

    Authors: Qin Zhao, Ke Shi, Zhi-gang Yang, Kai-yue Diao, Hua-yan Xu, Xi Liu and Ying-kun Guo
    Citation: BMC Cardiovascular Disorders 2018 18:124
    Content type: Research article Published on:

  42. Evidences suggest that central hemodynamics indexes are independent predictors of future cardiovascular events and all-cause mortality. Multiple factors have been pointed to have potential influence on central...

    Authors: Valeria Aparecida Costa-Hong, Henrique Cotchi Simbo Muela, Thiago Andrade Macedo, Allan Robson Kluser Sales and Luiz Aparecido Bortolotto
    Citation: BMC Cardiovascular Disorders 2018 18:123
    Content type: Research article Published on:

  43. Percutaneous coronary interventions (PCI) of old calcified saphenous vein grafts (SVGs) is challenging and is associated with a considerably high risk of adverse ischemic events in the short- and long-term as ...

    Authors: Mariano Pellicano, Vincent Floré, Emanuele Barbato and Bernard De Bruyne
    Citation: BMC Cardiovascular Disorders 2018 18:122
    Content type: Case report Published on:

  44. It is well recognized that cardio- vascular risk factors lead to histological and functional changes in aorta, and aortic stiffness is the best predictor of cardiovascular morbidity and mortality. In this stud...

    Authors: Fereshteh Ghaderi, Hossein Samim, Faeze Keihanian and Seyed Ali Danesh Sani
    Citation: BMC Cardiovascular Disorders 2018 18:121
    Content type: Research article Published on:

  45. In a previous study, we found that titrating clopidogrel maintenance doses (MDs) according to vasodilator-stimulated phosphoprotein (VASP) monitoring minimised the rate of major adverse cardiovascular and cere...

    Authors: Chaoyue Hu, Xumin Zhang, Yonghua Liu, Yang Gao, Xiaohong Zhao, Hua Zhou, Yu Luo, Yaling Liu and Xiaodong Wang
    Citation: BMC Cardiovascular Disorders 2018 18:120
    Content type: Research article Published on:

  46. The aim of this study was to describe maternal and fetal outcomes after pregnancy complicated by peripartum cardiomyopathy (PPCM).

    Authors: Nobila Valentin Yaméogo, André Koudnoaga Samadoulougou, Larissa Justine Kagambèga, Koudougou Jonas Kologo, Georges Rosario Christian Millogo, Anna Thiam, Charles Guenancia and Patrice Zansonré
    Citation: BMC Cardiovascular Disorders 2018 18:119
    Content type: Research article Published on:

  47. Kawasaki disease is an acute febrile disease with mucocutaneous and cardiovascular involvement affecting infants and young children. Though coronary artery abnormalities are common in Kawasaki disease, no cons...

    Authors: Xu Guo, Xiaoou Wang, Xinzhong Zhang, Ahmed O. Ahmed, David H. Hsi and Daqing Zhang
    Citation: BMC Cardiovascular Disorders 2018 18:118
    Content type: Case report Published on:

  48. Previous studies have reported slightly higher stroke rates in Takotsubo Syndrome compared to acute myocardial infarction. Our goal was to evaluate the temporal course of stroke rates and left ventricular reco...

    Authors: Nadine Abanador-Kamper, Lars Kamper, Judith Wolfertz, Marc Vorpahl, Patrick Haage and Melchior Seyfarth
    Citation: BMC Cardiovascular Disorders 2018 18:117
    Content type: Research article Published on:

  49. Transmural acute myocardial infarction (AMI) is associated with a high risk for ventricular arrhythmia before, during and after treatment. Consequently, it is recommended that patients diagnosed with transmura...

    Authors: Marco Albanese, Korhan Alpaslan, Taoufik Ouarrak, Peter Merguet, Steffen Schneider and Wolfgang Schöls
    Citation: BMC Cardiovascular Disorders 2018 18:116
    Content type: Research article Published on:

  50. Although several meta-analyses have demonstrated the utility of intravascular ultrasound (IVUS) in guiding drug-eluting stent (DES) implantation compared to angiography-guidance, there has been a dearth of evi...

    Authors: Yue Wang, Gary S. Mintz, Zhichun Gu, Yue Qi, Yue Wang, Mengru Liu and Xiaofan Wu
    Citation: BMC Cardiovascular Disorders 2018 18:115
    Content type: Research article Published on:
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BMC Cardiovascular Disorders

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