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  1. Coronary artery disease (CAD) is showing an increasing trend in young adults. Cigarette smoking has been shown to be a major cause of premature CAD. Previous studies have also shown that hyperuricemia (HUA) is...

    Authors: Sai Lv, Wei Liu, Yujie Zhou, Yuyang Liu, Dongmei Shi, Yingxin Zhao and Xiaoli Liu
    Citation: BMC Cardiovascular Disorders 2018 18:178
  2. Patients with frequent premature ventricular contractions (PVCs) are often symptomatic. Catheter ablation was usually indicated to eliminate symptoms in patients with PVCs-induced cardiomyopathy. Currently, PV...

    Authors: Jin-sheng Wang, Yi-gen Shen, Ri-peng Yin, Saroj Thapa, Yang-pei Peng, Kang-ting Ji, Lian-ming Liao, Jia-feng Lin and Yang-jing Xue
    Citation: BMC Cardiovascular Disorders 2018 18:177
  3. Reliability of models for estimating pretest probability (PTP) of obstructive coronary artery disease (CAD) has not been investigated in individuals at low extreme of traditional risk factor (RF) burden. Thus,...

    Authors: Minghui Wang, Yujie Liu, Xiujun Zhou, Jia Zhou, Hong Zhang and Ying Zhang
    Citation: BMC Cardiovascular Disorders 2018 18:176
  4. Many previous clinical studies have reported that prolongation of the QT interval corrected for heart rate (QTc) is associated with an increased risk of sudden cardiac death and all-cause mortality. This study...

    Authors: Yintao Chen, Xiaofan Guo, Guozhe Sun, Zhao Li, Liqiang Zheng and Yingxian Sun
    Citation: BMC Cardiovascular Disorders 2018 18:175
  5. Anticoagulation therapy is a standard treatment for stroke prevention in patients with non-valvular atrial fibrillation (NVAF) that have risk factors for stroke. However, anticoagulant increases the risk of bl...

    Authors: Rungroj Krittayaphong, Arjbordin Winijkul, Komsing Methavigul, Wattana Wongtheptien, Chaiyasith Wongvipaporn, Treechada Wisaratapong, Rapeephon Kunjara-Na-Ayudhya, Smonporn Boonyaratvej, Chulalak Komoltri, Pontawee Kaewcomdee, Ahthit Yindeengam and Piyamitr Sritara
    Citation: BMC Cardiovascular Disorders 2018 18:174
  6. Non-obstructive coronary artery disease (NOCAD) is a common finding on coronary angiography. Our goal was to evaluate the long-term prognosis of NOCAD patients with stable angina (SA).

    Authors: Christine K. Kissel, Guanmin Chen, Danielle A. Southern, P. Diane Galbraith and Todd J. Anderson
    Citation: BMC Cardiovascular Disorders 2018 18:173
  7. Transplant renal artery stenosis (TRAS) is a serious complication after renal transplantation, leading to hypertension, deterioration in renal function, and/or graft loss. The incidence of TRAS reportedly vari...

    Authors: Yoshito Kadoya, Kan Zen and Satoaki Matoba
    Citation: BMC Cardiovascular Disorders 2018 18:172
  8. The interventional left atrial appendage closure (LAAC) is a guideline-conform alternative to oral anticoagulation (OAC) in non-valvular atrial fibrillation patients with OAC ineligibility. It was aimed to dir...

    Authors: Christian Fastner, Lea Hoffmann, Mohamed Aboukoura, Michael Behnes, Siegfried Lang, Martin Borggrefe, Ibrahim Akin and Christoph A. Nienaber
    Citation: BMC Cardiovascular Disorders 2018 18:171
  9. The Orsiro biodegradable polymer sirolimus-eluting stent (O-SES) is a new-generation biodegradable polymer drug-eluting stent with the thinnest strut thickness to date developed to improve the percutaneous tre...

    Authors: Ping Zhu, Xin Zhou, Chenliang Zhang, Huakang Li, Zhihui Zhang and Zhiyuan Song
    Citation: BMC Cardiovascular Disorders 2018 18:170
  10. Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activatio...

    Authors: Edward C. A. Marks, Tom M. Wilkinson, Chris M. Frampton, Lorraine Skelton, Anna P. Pilbrow, Tim G. Yandle, Chris J. Pemberton, Robert N. Doughty, Gillian A. Whalley, Chris J. Ellis, Richard W. Troughton, Maurice C. Owen, Neil R. Pattinson, Vicky A. Cameron, A. Mark Richards, Steven P. Gieseg…
    Citation: BMC Cardiovascular Disorders 2018 18:169
  11. Pulmonary vein isolation (PVI), a cornerstone for catheter ablation of atrial fibrillation (AF), remains a complex and time-consuming procedure. Present study introduces a novel, circular-irrigated, deca-chann...

    Authors: Xiang-Fei Feng, Mu Chen, Jian Sun, Jie Sun, Bo Liang, Yi-Yong Sun and Yi-Gang Li
    Citation: BMC Cardiovascular Disorders 2018 18:168
  12. Cardiac rehabilitation improves prognosis after an acute myocardial infarction (AMI), however, the optimal method of implementation is unknown. The aim of the study was to evaluate the effect of individually-t...

    Authors: Halldora Ögmundsdottir Michelsen, Marie Nilsson, Fredrik Scherstén, Ingela Sjölin, Alexandru Schiopu and Margret Leosdottir
    Citation: BMC Cardiovascular Disorders 2018 18:167
  13. The aim of the study was to explore associations between elevated red cell distribution width (RDW) and acute kidney injury (AKI) in patients undergoing cardiac surgery (CS-AKI).

    Authors: Zhouping Zou, Yamin Zhuang, Lan Liu, Bo Shen, Jiarui Xu, Wuhua Jiang, Zhe Luo, Jie Teng, Chunsheng Wang and Xiaoqiang Ding
    Citation: BMC Cardiovascular Disorders 2018 18:166
  14. There is a little evidence for the effects of catheter ablation (CA) on hard endpoints in patients with atrial fibrillation (AF) and heart failure (HF).

    Authors: Yingxu Ma, Fan Bai, Fen Qin, Yixi Li, Tao Tu, Chao Sun, Shenghua Zhou and Qiming Liu
    Citation: BMC Cardiovascular Disorders 2018 18:165
  15. The use of inappropriate elective Percutaneous Coronary Intervention (PCI) has decreased over time, but hospital-level variation in the use of inappropriate PCI persists. Understanding the barriers and facilit...

    Authors: Anne Lambert-Kerzner, Charles Maynard, Marina McCreight, Amy Ladebue, Katherine M. Williams, Kelty B. Fehling and Steven M. Bradley
    Citation: BMC Cardiovascular Disorders 2018 18:164
  16. This study aimed to evaluate cost-utility of baroreflex activation therapy (BAT) using the Barostim neoâ„¢ device (CVRx Inc., Minneapolis, MN, USA) compared with optimized medical management in patients with advanc...

    Authors: Oleg Borisenko, Jochen Müller-Ehmsen, JoAnn Lindenfeld, Erik Rafflenbeul and Christian Hamm
    Citation: BMC Cardiovascular Disorders 2018 18:163
  17. Left ventricular (LV) hypertrophy and changes in LV geometry are associated with increased cardiovascular mortality. Subjects with type 2 diabetes have an increased risk of such alterations in cardiac morpholo...

    Authors: Susanne Rospleszcz, Anina Schafnitzel, Wolfgang Koenig, Roberto Lorbeer, Sigrid Auweter, Cornelia Huth, Wolfgang Rathmann, Margit Heier, Birgit Linkohr, Christa Meisinger, Holger Hetterich, Fabian Bamberg and Annette Peters
    Citation: BMC Cardiovascular Disorders 2018 18:162
  18. Adaptor-related protein complex 2 alpha 2 subunit (AP2A2) gene encodes a protein-a subunit of the AP-2 adaptor protein complex. Evidence has revealed that benzodiazepine receptor-associated protein 1 (BZRAP1) ...

    Authors: Sibo Wang, Zhihui Ma, Yongjun Zhang, Yankui Ding, Zhong Chen and Liansheng Wang
    Citation: BMC Cardiovascular Disorders 2018 18:161
  19. Understanding the determinants associated with prediabetes and type 2 diabetes in coronary patients may help to individualize treatment and modelling interventions. We sought to identify sociodemographic, medi...

    Authors: John Munkhaugen, Jøran Hjelmesæth, Jan Erik Otterstad, Ragnhild Helseth, Stina Therese Sollid, Erik Gjertsen, Lars Gullestad, Joep Perk, Torbjørn Moum, Einar Husebye and Toril Dammen
    Citation: BMC Cardiovascular Disorders 2018 18:160
  20. Heart failure (HF) and frailty often co-exist, and frailty in HF results in a poor prognosis. However, in Asian populations, prognostic criteria are needed to examine the effect of frailty on HF. Therefore, we...

    Authors: Sumio Yamada, Takuji Adachi, Hideo Izawa, Toyoaki Murohara and Takaaki Kondo
    Citation: BMC Cardiovascular Disorders 2018 18:159
  21. Hypertensive crises are clinical syndromes grouped as hypertensive urgency and emergency, which occur as complications of untreated or inadequately treated hypertension. Emergency departments across the world ...

    Authors: Patrick J. Shao, Hendry R. Sawe, Brittany L. Murray, Juma A. Mfinanga, Victor Mwafongo and Michael S. Runyon
    Citation: BMC Cardiovascular Disorders 2018 18:158
  22. The aim of the study was to investigate the high-sensitivity troponin T (hs-TnT) release profile in off-pump coronary artery bypass grafting (OPCABG) patients with normal postoperative course.

    Authors: Wen Ge, Chang Gu, Chao Chen, Wangwang Chen, Zhengqiang Cang, Yuliang Wang, Chennan Shi and Yangyang Zhang
    Citation: BMC Cardiovascular Disorders 2018 18:157
  23. Angina pectoris (AP) and unheralded myocardial infarction (MI) are considered random clinical equivalents of ischemic heart disease (IHD). Aim of the study was to evaluate the long-term progression of AP as op...

    Authors: Clara Carpeggiani, Claudio Michelassi, Patrizia Landi and Antonio L’Abbate
    Citation: BMC Cardiovascular Disorders 2018 18:156
  24. Recent clinical trials have shown that pulmonary artery pressure-guided therapy via the CardioMEMSâ„¢ system reduces the risk of recurrent hospitalizations in chronic heart failure (HF) patients. The CardioMEMSâ„¢...

    Authors: Carsten Tschöpe, Alessio Alogna, Frank Spillmann, Alessandro Faragli, Gunther Schmidt, Florian Blaschke, Uwe Kühl, Ewa Hertel, Monika Willner, Daniel Morris, Heiner Post, Michel Noutsias, Burkert Pieske and Florian Krackhardt
    Citation: BMC Cardiovascular Disorders 2018 18:155
  25. The stress in the ascending aorta results from many biomechanical factors including the geometry of the vessel and its maximum dimensions, arterial blood pressure and longitudinal systolic stretching due to he...

    Authors: Tomasz Plonek, Mikolaj Berezowski, Jacek Kurcz, Przemyslaw Podgorski, Marek SÄ…siadek, Bartosz Rylski, Andrzej Mysiak and Marek Jasinski
    Citation: BMC Cardiovascular Disorders 2018 18:154
  26. Left atrial appendage morphology has been proved to be an important predictor of left atrial thrombus (LAT) and left atrial spontaneous echo contrast (LASEC) and stroke in patients with non-valvular atrial fib...

    Authors: Fan Wang, Mengyun Zhu, Xiaoyu Wang, Wei Zhang, Yang Su, Yuyan Lu, Xin Pan, Di Gao, Xianling Zhang, Wei Chen, Yawei Xu, Yuxi Sun and Dachun Xu
    Citation: BMC Cardiovascular Disorders 2018 18:153
  27. Lipomatous hypertrophy of the atrial septum (LHAS) is an anomaly of the heart. It is characterized by an infiltration of adipocytes into myocytes of the interatrial septum, sparing the fossa ovalis, which give...

    Authors: Grzegorz Bielicki, Marceli Lukaszewski, Kinga Kosiorowska, Jacek Jakubaszko, Rafal Nowicki and Marek Jasinski
    Citation: BMC Cardiovascular Disorders 2018 18:152
  28. Ischemic Heart Disease (IHD) is the first ranked among most common causes of death involving cardiovascular and other diseases. The information on the prevalence of IHD in Thailand is lacking especially among ...

    Authors: Boonsub Sakboonyarat and Ram Rangsin
    Citation: BMC Cardiovascular Disorders 2018 18:151
  29. Hypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours dise...

    Authors: Nkengla Menka Adidja, Valirie Ndip Agbor, Jeannine A. Aminde, Calypse A. Ngwasiri, Kathleen Blackett Ngu and Leopold Ndemnge Aminde
    Citation: BMC Cardiovascular Disorders 2018 18:150
  30. In patients with Noonan syndrome (NS), cardiac disorders such as pulmonary valve stenosis (PS) or hypertrophic cardiomyopathy (HCM) are common. While some patients can develop heart failure associated with HCM...

    Authors: Yoshito Kadoya, Tsuneaki Kenzaka, Yohei Oda and Satoaki Matoba
    Citation: BMC Cardiovascular Disorders 2018 18:148
  31. Nonalcoholic fatty liver disease (NAFLD) refers to fatty infiltration of liver in the absence of excessive alcohol abuse. However, the problem that whether NAFLD is correlated with subclinical atherosclerosis ...

    Authors: Jilin Zheng, Yong Zhou, Kuo Zhang, Yu Qi, Shimin An, Siyuan Wang, Xingquan Zhao and Yi-Da Tang
    Citation: BMC Cardiovascular Disorders 2018 18:147
  32. It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in p...

    Authors: M. Skowerski, I. Wozniak-Skowerska, A. Hoffmann, S. Nowak, T. Skowerski, M. Sosnowski, A. M. Wnuk-Wojnar and K. Mizia-Stec
    Citation: BMC Cardiovascular Disorders 2018 18:146
  33. Extent of myocardial fibrosis (MF) determined using late gadolinium enhanced (LGE) predicts outcomes, but gadolinium is contraindicated in advanced renal disease. We assessed the ability of native T1-mapping t...

    Authors: M. P. Graham-Brown, A. S. Singh, G. S. Gulsin, E. Levelt, J. A. Arnold, D. J. Stensel, J. O. Burton and G. P. McCann
    Citation: BMC Cardiovascular Disorders 2018 18:145
  34. The potential life-threatening consequences of catecholamine use for emergency circulatory support in Takotsubo cardiomyopathy-related acute heart failure is a major challenge in cardiovascular emergences. In ...

    Authors: Michael Dandel and Roland Hetzer
    Citation: BMC Cardiovascular Disorders 2018 18:144
  35. The xanthine oxidase inhibitor allopurinol that is commonly used to treat gout, has been suggested to have pleiotropic effects that are likely to reduce the incidence of myocardial infarction (MI) in at risk i...

    Authors: Tejas P. Singh, Tristan Skalina, Daniel Nour, Aarya Murali, Sean Morrison, Joseph V. Moxon and Jonathan Golledge
    Citation: BMC Cardiovascular Disorders 2018 18:143
  36. Intracardiac invasion of head and neck cancer is extremely rare. Here, we report a case of recurred oral cavity cancer presenting with complete atrioventricular (AV) block caused by cardiac metastasis.

    Authors: Jae Yeong Cho, Kye Hun Kim, Hyukjin Park, Hyun Ju Yoon and Jong Chun Park
    Citation: BMC Cardiovascular Disorders 2018 18:142
  37. Inflammation is a common feature of both peripheral arterial disease (PAD) and periodontitis. Some studies have evaluated the association between PAD and periodontitis. However, there is still no specialized m...

    Authors: Shuo Yang, Li Sheng Zhao, Chuan Cai, Quan Shi, Ning Wen and Juan Xu
    Citation: BMC Cardiovascular Disorders 2018 18:141
  38. The cardiovascular disease risk was assessed in metabolically healthy obese (MHO) children, obese children with metabolic disorders (MUO), and to a control group of normal-weight children using carotid intima-...

    Authors: Giovanni Farello, Annarita Antenucci, Stefano Stagi, Chiara Mazzocchetti, Franco Ciocca and Alberto Verrotti
    Citation: BMC Cardiovascular Disorders 2018 18:140
  39. The EPICOR Asia (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) study (NCT01361386) was an observational study of patients hospitalized for acute coronar...

    Authors: Stephen Jan, Stephen W-L. Lee, Jitendra P. S. Sawhney, Tiong K. Ong, Chee Tang Chin, Hyo-Soo Kim, Rungroj Krittayaphong, Vo T. Nhan, Stuart J. Pocock, Ana M. Vega, Nobuya Hayashi and Yong Huo
    Citation: BMC Cardiovascular Disorders 2018 18:139
  40. Despite marked advances in our understanding of the pathophysiology of the coronary slow flow phenomenon (CSFP), the exact mechanism remains unclear. Previous studies have suggested that CSFP might be associat...

    Authors: Yong Wang, Mou-jie Liu, Hui-min Yang, Chun-yan Ma, Peng-yu Jia, Da-lin Jia and Ai-jie Hou
    Citation: BMC Cardiovascular Disorders 2018 18:138
  41. In Denmark and other countries, there has been a shift in the management of patients with an implantable cardioverter defibrillator (ICD) with remote device monitoring largely replacing in-hospital visits. Les...

    Authors: Susanne S. Pedersen, Søren J. Skovbakke, Uffe K. Wiil, Thomas Schmidt, Rene dePont Christensen, Carl J. Brandt, Jan Sørensen, Michael Vinther, Charlotte E. Larroudé, Thomas M. Melchior, Sam Riahi, Kim G. E. Smolderen, John A. Spertus, Jens B. Johansen and Jens C. Nielsen
    Citation: BMC Cardiovascular Disorders 2018 18:136
  42. The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research component of a broad program aimed at primary and s...

    Authors: John Musuku, Mark E. Engel, Patrick Musonda, Joyce Chipili Lungu, Elizabeth Machila, Sherri Schwaninger, Agnes Mtaja, Evans Mulendele, Dorothy Kavindele, Jonathan Spector, Brigitta Tadmor, Marcelo M. Gutierrez, Joris Van Dam, Laurence Colin, Aidan Long, Mark C. Fishman…
    Citation: BMC Cardiovascular Disorders 2018 18:135
  43. Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop into chronic myocarditis and dilated cardiomyopathy in some patients. We report a case of vir...

    Authors: Tetsuya Yamamoto, Tsuneaki Kenzaka, Masanori Matsumoto, Ryo Nishio, Satoru Kawasaki and Hozuka Akita
    Citation: BMC Cardiovascular Disorders 2018 18:134
  44. To explore the effects of chronic intermittent hypoxia (CIH), which mimics sleep apnea syndrome, on the cardiac renin angiotensin system (RAS), and to investigate the cardiac protection of an angiotensin recep...

    Authors: Wanyu Wang, Ailing Song, Yiming Zeng, Xiaoyang Chen, Yixiang Zhang, Yonghong Shi, Yihua Lin and Wen Luo
    Citation: BMC Cardiovascular Disorders 2018 18:133
  45. The stenosis of the coronary arteries is usually caused by atherosclerosis. Hemodynamic significance of patient-specific coronary stenoses and the risk of its progression may be assessed by comparing the hemod...

    Authors: Zbigniew Malota, Jan Glowacki, Wojciech Sadowski and Marcin Kostur
    Citation: BMC Cardiovascular Disorders 2018 18:132
  46. In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferio...

    Authors: Claudius Hansen, Christian Loges, Karlheinz Seidl, Frank Eberhardt, Herbert Tröster, Krum Petrov, Gerian Grönefeld, Peter Bramlage, Frank Birkenhauer and Christian Weiss
    Citation: BMC Cardiovascular Disorders 2018 18:131
  47. Nonculprit lesions are the major cause of future cardiovascular events. However, the natural course of nonculprit lesions and angiographic predictors of plaque progression are not well-studied. The purpose of ...

    Authors: Jeehoon Kang, Kyung Woo Park, Michael S. Lee, Chengbin Zheng, Jung-Kyu Han, Han-Mo Yang, Hyun-Jae Kang, Bon-Kwon Koo and Hyo-Soo Kim
    Citation: BMC Cardiovascular Disorders 2018 18:130
  48. Heart failure (HF) with preserved ejection fraction (HFpEF) comprises nearly half of prevalent HF, yet is challenging to curate in a large database of electronic medical records (EMR) since it requires both ac...

    Authors: Yash R. Patel, Jeremy M. Robbins, Katherine E. Kurgansky, Tasnim Imran, Ariela R. Orkaby, Robert R. McLean, Yuk-Lam Ho, Kelly Cho, J. Michael Gaziano, Luc Djousse, David R. Gagnon and Jacob Joseph
    Citation: BMC Cardiovascular Disorders 2018 18:128

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