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  1. Acute aortic dissection (AAD) is a life-threatening disorder in vascular surgery with a high early mortality. Serum amyloid A (SAA) is a kind of acute-phase protein with a rapid diagnostic value in other disea...

    Authors: Yuchen He, Changcheng Ma, Jia Xing, Shiyue Wang, Chao Ji, Yanshuo Han and Jian Zhang
    Citation: BMC Cardiovascular Disorders 2019 19:282
  2. Advanced echocardiography techniques such as speckle tracking imaging are sensitive diagnostic tools frequently used in various clinical and scientific scenarios. Importantly, imperfect reproducibility and dep...

    Authors: Kai O. Hensel
    Citation: BMC Cardiovascular Disorders 2019 19:281
  3. In spite of the important role of Apolipoprotein-M (ApoM) and Sphingosine-1-Phosphate (S1P) played in atherosclerosis (AS), there was few related research reporting ApoM and S1P complex (ApoM-S1P) on biologica...

    Authors: Yang Liu and Li Tie
    Citation: BMC Cardiovascular Disorders 2019 19:279
  4. Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and glycemic control affect the pathogenesis of AF has not ...

    Authors: Qing Wang, Jing Wang, Pei Wang, Liaoyuan Wang, Lanting Jia, Xinyu Ling, Wang Xi, Jie Min, Hua Shen, Jian Xiao, Jinxiang Yuan and Zhinong Wang
    Citation: BMC Cardiovascular Disorders 2019 19:278
  5. Evidences regarding the associations between maternal upper respiratory tract infection/influenza during pregnancy and the risk of congenital heart disease (CHD) is still controversial. This study was specific...

    Authors: Y. Q. Xia, K. N. Zhao, A. D. Zhao, J. Z. Zhu, H. F. Hong, Y. L. Wang and S. H. Li
    Citation: BMC Cardiovascular Disorders 2019 19:277
  6. Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the preva...

    Authors: Qun Ma, Zhao Li, Xiaofan Guo, Liang Guo, Shasha Yu, Hongmei Yang, Lu Zou, Liqiang Zheng, Guowei Pan, Yonghong Zhang and Yingxian Sun
    Citation: BMC Cardiovascular Disorders 2019 19:276
  7. Korea has seen a rapid increase in the use of percutaneous coronary intervention (PCI) with the ratio of PCI to coronary artery bypass graft (CABG) the highest in the world. This study was performed to examine...

    Authors: Agnus M. Kim, Jong Heon Park, Seongcheol Cho, Sungchan Kang, Tae Ho Yoon and Yoon Kim
    Citation: BMC Cardiovascular Disorders 2019 19:275
  8. Cardiac rehabilitation (CR) uptake and adherence remain sub-optimal despite the apparent health benefits of modifying healthy behavior and slowing disease progression. eHealth is the use of information and com...

    Authors: Jing Jing Su and Doris Sau Fung Yu
    Citation: BMC Cardiovascular Disorders 2019 19:274
  9. The interventional treatment of chronic total occlusion (CTO) with stent fracture as well as severe calcification was extremely difficult and no effective technique has been reported.

    Authors: Yajun Xue, Boda Zhou, Weimin Wang, Guobin Miao, Ou Zhang, Jie Zhou, Yu Geng, Yanlong Zhai, Chunhui Ren and Ping Zhang
    Citation: BMC Cardiovascular Disorders 2019 19:273
  10. Coronary heart disease is related to sudden death caused by multi-factors and a major threat to human health.This study explores the role of OX40L and ICAM-1 in the stability of coronary plaques and their rela...

    Authors: Yu Wang, Xiaoyu Sun, Bing Xia, Cuiyun Le, Zhu Li, Jie Wang, Jiang Huang, Jiawen Wang and Changwu Wan
    Citation: BMC Cardiovascular Disorders 2019 19:272
  11. Cardiovascular disease including ST elevation myocardial infarction (STEMI) is increasing and the leading cause of death in China. There has been limited data available to characterize STEMI management and out...

    Authors: You Zhang, Shan Wang, Shuyan Yang, Shanshan Yin, Qianqian Cheng, Muwei Li, Datun Qi, Xianpei Wang, Zhongyu Zhu, Luosha Zhao, Dayi Hu and Chuanyu Gao
    Citation: BMC Cardiovascular Disorders 2019 19:271
  12. To estimate the prevalence of elevated blood glucose level (EBG, including type 2 diabetes mellitus and impaired fasting glucose), and its association with non-valvular atrial fibrillation (NVAF) in Guangzhou,...

    Authors: Lu Fu, Hai Deng, Wei-dong Lin, Shang-fei He, Fang-zhou Liu, Yang Liu, Xian-zhang Zhan, Xian-hong Fang, Hong-tao Liao, Wei Wei, Zi-li Liao, Li-hong Tang, Zu-yi Fu, Mu-rui Zheng, Shu-lin Wu and Yu-mei Xue
    Citation: BMC Cardiovascular Disorders 2019 19:270
  13. Several studies have reported on atrial fibrillation (AF) outcomes, including thromboembolism in patients with paroxysmal and non-paroxysmal AF; however the findings still remain controversial on whether risks...

    Authors: Ying Wang, Chang-Sheng Ma, Xin Du, Liu He, Jie Li, Guo-Hong Wang, Dan Wen, Jian-Zeng Dong, Jian-Hong Pan and Gregory Y. H. Lip
    Citation: BMC Cardiovascular Disorders 2019 19:283
  14. Hypertension and arterial vasculopathy may be mutual causes and effects. It is unknown whether carotid intima-media thickness (cIMT) is reliably predictive of the presence of newly developed hypertension in th...

    Authors: Long Zhang, Fangfang Fan, Litong Qi, Jia Jia, Ying Yang, Jianping Li and Yan Zhang
    Citation: BMC Cardiovascular Disorders 2019 19:269
  15. Cardiovascular disease (CVD) is the primary cause of death worldwide, accounting for 31.0% of all deaths and more than 18 million deaths annually. The 2008 World Health Report indicated that 144 (35%) of the 4...

    Authors: Ranya A. Ghamri, Nada S. Alzahrani, Amal M. Alharthi, Hana J. Gadah, Bayan G. Badoghaish and Azzah A. Alzahrani
    Citation: BMC Cardiovascular Disorders 2019 19:268
  16. Left ventricular global longitudinal strain (GLS) with cardiovascular magnetic resonance (CMR) is an important prognostic biomarker. Its everyday clinical use is limited due to methodological and postprocessin...

    Authors: Robert Heinke, Faraz Pathan, Melanie Le, Tommaso D’Angelo, Lea Winau, Christophe Arendt, Thomas J. Vogl, Andreas Zeiher, Eike Nagel and Valentina O. Puntmann
    Citation: BMC Cardiovascular Disorders 2019 19:267
  17. Although perioperative care during heart surgery has improved considerably, the rate of postoperative complications has remained stable. It has not been concluded how to better apply grip strength to clinical,...

    Authors: Liyuan Fu, Yuanyuan Zhang, Bohan Shao, Xiangjing Liu, Bo Yuan, Zhengqing Wang, Tienan Chen, Zhigang Liu, Xiaocheng Liu and Qi Guo
    Citation: BMC Cardiovascular Disorders 2019 19:266
  18. Coronary artery disease (CAD), including acute myocardial infarction (AMI), is a common complex disease. Although a great number of genetic loci and variants for CAD have been identified, genetic causes and un...

    Authors: Shuai Wang, Jie Zhang, Xiaohui He, Yexin Zhang, Jing Chen, Qiang Su, Shuchao Pang, Shufang Zhang, Yinghua Cui and Bo Yan
    Citation: BMC Cardiovascular Disorders 2019 19:265
  19. ST resolution (STR) after AMI is a non-invasive indicator of IRA reperfusion. We investigated whether pre-angiography STR predicted spontaneous IRA reperfusion in STEMI patients.

    Authors: Zongsheng Guo and Xinchun Yang
    Citation: BMC Cardiovascular Disorders 2019 19:264
  20. After publication of the original article [1], we were notified that the name of the software mentioned in the Background section is TAONET and not Tao Net.

    Authors: Bárbara Menéndez-Jándula, José Antonio García-Erce, Clara Zazo and Luis Larrad-Mur
    Citation: BMC Cardiovascular Disorders 2019 19:263

    The original article was published in BMC Cardiovascular Disorders 2019 19:186

  21. Hypertension is an established risk factor for the development of atrial fibrillation (AF). We evaluated the association and population impact of hypertension, defined using the new 2017 guidelines, on risk of...

    Authors: Anas Rattani, J’Neka S. Claxton, Mohammed K. Ali, Lin Y. Chen, Elsayed Z. Soliman and Alonso Alvaro
    Citation: BMC Cardiovascular Disorders 2019 19:262
  22. High risk of embolic events exists in both patients with chronic atrial fibrillation (AF) and patients in the perioperative period of ablation (effective treatment for AF). Therefore, anticoagulant therapy is ...

    Authors: Jian Yang, Xuan Zhang, Xi-ying Wang, Chi Zhang, Song-zan Chen and Shen-Jiang Hu
    Citation: BMC Cardiovascular Disorders 2019 19:261
  23. Depression often co-exists with non-cardiovascular morbid conditions. Whether this comorbidity increases the risk of cardiovascular disease has so far not been studied. Thus, the aim of this study was to deter...

    Authors: Aysha Almas, Jette Moller, Romaina Iqbal, Andreas Lundin and Yvonne Forsell
    Citation: BMC Cardiovascular Disorders 2019 19:260
  24. Cardiovascular disease (CVD) imposes much mortality and morbidity worldwide. The use of “deep learning”, advancements in genomics, metabolomics, proteomics and devices like wearables have the potential to unea...

    Authors: Jonathan Yap, Weng Khong Lim, Anders Sahlén, Calvin Woon-Loong Chin, Kenneth Michael Yun-Chi Chew, Sonia Davila, John Allen, Vera Goh, Swee Yaw Tan, Patrick Tan, Carolyn S. P. Lam, Stuart Alexander Cook and Khung Keong Yeo
    Citation: BMC Cardiovascular Disorders 2019 19:259
  25. The new ACC/AHA hypertension guideline lower the definition of hypertension from 140/90 mmHg to 130/80 mmHg and eliminate the category of prehypertension thus increasing the prevalence of hypertension. A purpo...

    Authors: Yanxia Xie, Mingfeng Ma, Zhao Li, Xiaofan Guo, Guozhe Sun, Zhaoqing Sun, Jia Zheng, Yingxian Sun and Liqiang Zheng
    Citation: BMC Cardiovascular Disorders 2019 19:258
  26. Increasing evidence has been presented which suggests that left ventricular (LV) diastolic dysfunction may play an important role in the development of atrial fibrillation (AF). However, the potential for LV d...

    Authors: Fengjiao Chen, Qinliang Sun, Hairu Li, Shaohui Qu, Weidong Yu, Shuangquan Jiang and Jiawei Tian
    Citation: BMC Cardiovascular Disorders 2019 19:257
  27. Depression is associated with increased mortality and poor prognosis in patients with cardiovascular disease (CVD). However, little is known about the patient characteristics associated with new onset post hea...

    Authors: Serdar Sever, Patrick Doherty, Alexander Stephen Harrison and Su Golder
    Citation: BMC Cardiovascular Disorders 2019 19:256
  28. The risk of sudden cardiac death (SCD) is known to be dynamic. However, the accuracy of a dynamic SCD prediction is unknown. We aimed to measure the dynamic predictive accuracy of ECG biomarkers of SCD and com...

    Authors: Erick A. Perez-Alday, Aron Bender, David German, Srini V. Mukundan, Christopher Hamilton, Jason A. Thomas, Yin Li-Pershing and Larisa G. Tereshchenko
    Citation: BMC Cardiovascular Disorders 2019 19:255
  29. The PhysioHeart™ is a mature acute platform, based isolated slaughterhouse hearts and able to validate cardiac devices and techniques in working mode. Despite perfusion, myocardial edema and time-dependent fun...

    Authors: Benjamin Kappler, Carlos A. Ledezma, Sjoerd van Tuijl, Veronique Meijborg, Bastiaan J. Boukens, Bülent Ergin, P. J. Tan, Marco Stijnen, Can Ince, Vanessa Díaz-Zuccarini and Bas A. J. M. de Mol
    Citation: BMC Cardiovascular Disorders 2019 19:254
  30. Individuals with established cardiovascular disease (CVD) and risk factors such as age, smoking, hypertension, and diabetes mellitus are at an increased risk of recurrent cardiovascular events and death. The i...

    Authors: Romona D. Govender, Saif Al-Shamsi, Elpidoforos S. Soteriades and Dybesh Regmi
    Citation: BMC Cardiovascular Disorders 2019 19:253
  31. To assess the value of D-dimer and its combination with The Global Registry of Acute Coronary Events (GRACE) score in predicting in-hospital mortality in patients with acute coronary syndrome (ACS) undergoing ...

    Authors: Tongtong Yu, Yundi Jiao, Jia Song, Dongxu He, Jiake Wu, Zhijun Sun and Zhaoqing Sun
    Citation: BMC Cardiovascular Disorders 2019 19:252
  32. Heart failure (HF) is a major public health problem with increasing prevalence worldwide. It is associated with high mortality and poor quality of life due to recurrent and costly hospital admissions. Several ...

    Authors: Luciana Gioli-Pereira, Fabiana G. Marcondes-Braga, Sabrina Bernardez-Pereira, Fernando Bacal, Fábio Fernandes, Alfredo J. Mansur, Alexandre C. Pereira and José E. Krieger
    Citation: BMC Cardiovascular Disorders 2019 19:251
  33. Pulmonary embolism (PE) is associated to high mortality rate worldwide. However, the diagnosis of PE often results inaccurate. Many cases of PE are incorrectly diagnosed or missed and they are often associated...

    Authors: Gelsomina Mansueto, Dario Costa, Emanuele Capasso, Federica Varavallo, Giuseppina Brunitto, Rosanna Caserta, Salvatore Esposito, Massimo Niola, Celestino Sardu, Raffaele Marfella, Claudio Napoli and Mariano Paternoster
    Citation: BMC Cardiovascular Disorders 2019 19:250
  34. Conventional pharmacologic therapies aim to reduce fluid overload in advanced heart failure (HF) represented by intravenous (IV) loop diuretics (LDs) have sometimes not so efficacious and been reported to have...

    Authors: Ying Yang, Chao Shen, Jiangting Lu, Fen Xu, Jinshan Tong, Jiangfen Jiang and Guosheng Fu
    Citation: BMC Cardiovascular Disorders 2019 19:249
  35. There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated.

    Authors: Fatemeh Gholami, Ghobad Moradi, Bushra Zareei, Mohammad Aziz Rasouli, Bahram Nikkhoo, Daem Roshani and Ebrahim Ghaderi
    Citation: BMC Cardiovascular Disorders 2019 19:248
  36. Normal findings of cardiac scintigraphy predict good outcomes. However, a paucity of the data exists for elderly patients 85 years or older. In the present study, we aimed to demonstrate the association betwee...

    Authors: Takao Kato, Mitsumasa Okano, Yoshizumi Haruna and Moriaki Inoko
    Citation: BMC Cardiovascular Disorders 2019 19:246
  37. The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued mi...

    Authors: Benjaporn Chinprateep, Nithima Ratanasit, Yodying Kaolawanich, Khemajira Karaketklang, Pairash Saiviroonporn, Vip Viprakasit and Rungroj Krittayaphong
    Citation: BMC Cardiovascular Disorders 2019 19:245
  38. The independent association of neck circumference (NC) on elevated blood pressure is still uncertain in adults of China. The aim of this study is to explore such association and investigate the predictive valu...

    Authors: Huijing He, Li Pan, Feng Liu, Jingang Ma, Li Wang, Zhiping Hu, Yajun Li and Guangliang Shan
    Citation: BMC Cardiovascular Disorders 2019 19:244
  39. Secondary prevention after an acute myocardial infarction (AMI) reduces morbidity and mortality, but suboptimal secondary prevention of cardiovascular disease is common. Therefore, the present study aimed to i...

    Authors: Maria Sakalaki, Salim Barywani, Annika Rosengren, Lena Björck and Michael Fu
    Citation: BMC Cardiovascular Disorders 2019 19:243
  40. Cardiac rehabilitation (CR) programs provide significant benefit for people with cardiovascular disease. Despite these benefits, such services are not universally available. We designed and evaluated a nationa...

    Authors: Bonnie J. Wakefield, Kariann Drwal, Monica Paez, Sara Grover, Carrie Franciscus, Heather Schacht Reisinger, Peter J. Kaboli and Ramzi El Accaoui
    Citation: BMC Cardiovascular Disorders 2019 19:242
  41. Hypertension (HTN) is major public health challenge. Data on HTN prevalence and associated risk factors is necessary to better control it. This study aimed at estimating the prevalence of HTN and associated an...

    Authors: Biniem Hassen and Hassen Mamo
    Citation: BMC Cardiovascular Disorders 2019 19:241
  42. We characterised the phenotypic consequence of genetic variation at the PCSK9 locus and compared findings with recent trials of pharmacological inhibitors of PCSK9.

    Authors: Amand F. Schmidt, Michael V. Holmes, David Preiss, Daniel I. Swerdlow, Spiros Denaxas, Ghazaleh Fatemifar, Rupert Faraway, Chris Finan, Dennis Valentine, Zammy Fairhurst-Hunter, Fernando Pires Hartwig, Bernardo Lessa Horta, Elina Hypponen, Christine Power, Max Moldovan, Erik van Iperen…
    Citation: BMC Cardiovascular Disorders 2019 19:240
  43. Identifying variables predictive of acute myocardial infarction (AMI) in women is important. The use of the ratio of total cholesterol-to-high density lipoprotein cholesterol (TC/HDL-C) is often overlooked. Th...

    Authors: Susanna Calling, Sven-Erik Johansson, Moa Wolff, Jan Sundquist and Kristina Sundquist
    Citation: BMC Cardiovascular Disorders 2019 19:239
  44. Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat di...

    Authors: Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Nicholas J. Wareham and Kay-Tee Khaw
    Citation: BMC Cardiovascular Disorders 2019 19:238
  45. Cardiac catheterization is performed for both therapeutic and diagnostic reasons, in which the outcome may vary from only medical treatment to the need of percutaneous coronary intervention and ending with cor...

    Authors: Abdulsalam Alkaiyat, Reham Abumadi, Shuruq Atari, Wasef Sayeh, Hamzeh Al Zabadi, Zaid Sarawan, Fekri Bisharat and Nizar Shakhshir
    Citation: BMC Cardiovascular Disorders 2019 19:237
  46. Care coordination between general practitioners (GPs) and cardiovascular specialists is expected to play a key role in establishing appropriate oral anticoagulant (OAC) treatment in atrial fibrillation (AF) pa...

    Authors: Fumiko Ono, Sayako Akiyama, Akifumi Suzuki, Yoshinobu Ikeda, Akira Takahashi, Hitoshi Matsuoka, Masahiro Sasaki, Tomonori Okamura and Nariaki Yoshihara
    Citation: BMC Cardiovascular Disorders 2019 19:235
  47. The risk of peripheral artery disease (PAD) in patients with diabetes mellitus (DM) and coronary artery disease (CAD) is an important and inadequately addressed issue. Our aim is to examine the impact of DM on...

    Authors: Sadaf Kamil, Thomas S. G. Sehested, Nicholas Carlson, Kim Houlind, Jens F. Lassen, Casper N. Bang, Helena Dominguez, Christian T. Pedersen and Gunnar H. Gislason
    Citation: BMC Cardiovascular Disorders 2019 19:234

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