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  1. Most studies providing data on survival in patients with atherosclerosis only address a single disease site: heart, brain or legs. Therefore, our objective was to determine risk of death after first hospital a...

    Authors: Ilonca Vaartjes, Ineke van Dis, Diederick E Grobbee and Michiel L Bots

    Citation: BMC Cardiovascular Disorders 2010 10:57

    Content type: Research article

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  2. Aortic calcification is a major risk factor for death from cardiovascular disease. We investigated the relationship between mortality and the composite markers of number, size, morphology and distribution of c...

    Authors: Mads Nielsen, Melanie Ganz, Francois Lauze, Paola C Pettersen, Marleen de Bruijne, Thomas B Clarkson, Erik B Dam, Claus Christiansen and Morten A Karsdal

    Citation: BMC Cardiovascular Disorders 2010 10:56

    Content type: Research article

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  3. Blood pressure (BP) variability has been associated with cardiovascular outcomes, but there is no consensus about the more effective method to measure it by ambulatory blood pressure monitoring (ABPM). We eval...

    Authors: Estefânia Wittke, Sandra C Fuchs, Flávio D Fuchs, Leila B Moreira, Elton Ferlin, Fábio T Cichelero, Carolina M Moreira, Jeruza Neyeloff, Marina B Moreira and Miguel Gus

    Citation: BMC Cardiovascular Disorders 2010 10:55

    Content type: Research article

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  4. Optimal manual closed chest compressions are difficult to give. A mechanical compression/decompression device, named LUCAS, is programmed to give compression according to the latest international guidelines (2...

    Authors: Qiuming Liao, Trygve Sjöberg, Audrius Paskevicius, Björn Wohlfart and Stig Steen

    Citation: BMC Cardiovascular Disorders 2010 10:53

    Content type: Research article

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  5. Atrio-esophageal fistula formation following radiofrequency ablation of left atrial tachyarrhythmias is a rare but devastating complication. Esophageal injuries are believed to be precursors of fistula formati...

    Authors: Armin Sause, Osman Tutdibi, Karsten Pomsel, Wilfried Dinh, Reiner Füth, Mark Lankisch, Thomas Glosemeyer-Allhoff, Jan Janssen and Micheal Müller

    Citation: BMC Cardiovascular Disorders 2010 10:52

    Content type: Research article

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  6. The use of mechanical/physical devices for applying mild therapeutic hypothermia is the only proven neuroprotective treatment for survivors of out of hospital cardiac arrest. However, this type of therapy is c...

    Authors: Keld Fosgerau, Uno J Weber, Jacob W Gotfredsen, Magdalena Jayatissa, Carsten Buus, Niels B Kristensen, Mogens Vestergaard, Peter Teschendorf, Andreas Schneider, Philip Hansen, Jakob Raunsø, Lars Køber, Christian Torp-Pedersen and Charlotte Videbaek

    Citation: BMC Cardiovascular Disorders 2010 10:51

    Content type: Research article

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  7. Rural-to-urban migration in low- and middle-income countries causes an increase in individual cardiovascular risk. Cost-effective interventions at early stages of the natural history of coronary disease such a...

    Authors: M Justin S Zaman, Christian Loret de Mola, Robert H Gilman, Liam Smeeth and J Jaime Miranda

    Citation: BMC Cardiovascular Disorders 2010 10:50

    Content type: Research article

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  8. People with intermittent claudication are at increased risk of death from heart attack and stroke compared to matched controls. Surgery for intermittent claudication is for symptom management and does not redu...

    Authors: Maggie A Cunningham, Vivien Swanson, Ronan E O'Carroll and Richard J Holdsworth

    Citation: BMC Cardiovascular Disorders 2010 10:49

    Content type: Study protocol

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  9. Alport syndrome (AS) is a rare inherited disorder characterized by an inflammation of the kidneys and damage to the glomerular capillaries, ultimately leading to renal failure at an early age. To date, rare re...

    Authors: Pier Paolo Bassareo, Andrea Raffaele Marras and Giuseppe Mercuro

    Citation: BMC Cardiovascular Disorders 2010 10:48

    Content type: Case report

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  10. The MASS IV-DM Trial is a large project from a single institution, the Heart Institute (InCor), University of São Paulo Medical School, Brazil to study ventricular function and coronary arteries in patients wi...

    Authors: Whady Hueb, Neuza Lopes, Paulo R Soares, Bernard J Gersh, Eduardo Gomes Lima, Ricardo D´Oliveira Vieira, Cibele Larrosa Garzillo, Rosa Rhami Garcia, Alexandre Costa Pereira, Celia Maria Strunz, Claudio Meneguetti, Jeane Tsutsui, Jose Parga, Pedro Lemos, Alexandre Hueb, Augusto Ushida…

    Citation: BMC Cardiovascular Disorders 2010 10:47

    Content type: Study protocol

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  11. The INSIG2 gene has been implicated in cholesterol metabolism and a single nucleotide polymorphism (SNP) near INSIG2 has been shown to be associated with obesity. We sought to determine the relationship of the IN...

    Authors: Kimberly A Skelding, Glenn S Gerhard, Helen Vlachos, Faith Selzer, Sheryl F Kelsey, Xin Chu, Robert Erdman, David O Williams and Kevin E Kip

    Citation: BMC Cardiovascular Disorders 2010 10:46

    Content type: Research article

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  12. Polymorphonuclear neutrophils, stimulated by the activated complement factor C5a, have been implicated in cardiac ischemia/reperfusion injury. ADC-1004 is a competitive C5a receptor antagonist that has been sh...

    Authors: Jesper van der Pals, Sasha Koul, Patrik Andersson, Matthias Götberg, Joey FA Ubachs, Mikael Kanski, Håkan Arheden, Göran K Olivecrona, Bengt Larsson and David Erlinge

    Citation: BMC Cardiovascular Disorders 2010 10:45

    Content type: Research article

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  13. Lowering of blood pressure by antihypertensive drugs reduces the risks of cardiovascular events, stroke, and total mortality. However, poor adherence to antihypertensive medications reduces their effectiveness...

    Authors: Alfonso Leiva, Marta Fajó, Luís Escriche, Francisco J Audera, Sara López, Ma Carmén Martín, Rosa González, Gaspar Tamborero, Elena M García, Rosa Duro, Ramón Orueta, Francisca Serra, Pilar D'agosto P, Jerónima Miralles, Patricia Lorente, Joan Llobera…

    Citation: BMC Cardiovascular Disorders 2010 10:44

    Content type: Study protocol

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  14. Expanded endothelial progenitor cells (eEPC) improve global left ventricular function in experimental myocardial infarction (MI). Erythropoietin beta (EPO) applied together with eEPC may improve regional myoca...

    Authors: Andreas Stein, Martina Knödler, Markus Makowski, Sandra Kühnel, Stefan Nekolla, Alexandra Keithahn, Eliane Weidl, Philip Groha, Maren Schürmann, Atti Saraste, Rene Botnar, Robert AJ Oostendorp and Ilka Ott

    Citation: BMC Cardiovascular Disorders 2010 10:43

    Content type: Research article

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  15. To evaluate the midterm results of patients with angina and diffuse coronary artery disease treated with transmyocardial revascularization in combination with autologous stem cell therapy.

    Authors: Guillermo Reyes, Keith B Allen, Pablo Álvarez, Adrian Alegre, Beatriz Aguado, MariaJose Olivera, Paloma Caballero, JoseLuis Rodríguez and Juan Duarte

    Citation: BMC Cardiovascular Disorders 2010 10:42

    Content type: Research article

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  16. The clinical impact of PlA2 polymorphism has been investigated in several diseases, but the definition of its specific role on thrombotic cardiovascular complications has been challenging. We aimed to explore ...

    Authors: Gennaro Galasso, Gaetano Santulli, Federico Piscione, Roberta De Rosa, Valentina Trimarco, Raffaele Piccolo, Salvatore Cassese, Guido Iaccarino, Bruno Trimarco and Massimo Chiariello

    Citation: BMC Cardiovascular Disorders 2010 10:41

    Content type: Research article

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  17. Peripheral arterial disease (PAD) is caused by narrowing of the arteries in the lower extremities. Limited data exist concerning the impact of diffuse vascular disease (DVD) on prognosis and costs. Thus, the o...

    Authors: Kristen Migliaccio-Walle, Michael Stokes, Irina Proskorovsky, Dan Popovici-Toma and Wissam El-Hadi

    Citation: BMC Cardiovascular Disorders 2010 10:40

    Content type: Research article

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  18. Survivors of a cardiac arrest often have persistent cardiovascular derangements following cardiopulmonary resuscitation including decreased cardiac output, arrhythmias and morphological myocardial damage. Thes...

    Authors: Keld Fosgerau, Giuseppe Ristagno, Magdalena Jayatissa, Mads Axelsen, Jacob W Gotfredsen, Uno J Weber, Lars Køber, Christian Torp-Pedersen and Charlotte Videbaek

    Citation: BMC Cardiovascular Disorders 2010 10:39

    Content type: Research article

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  19. As populations in Western countries continue to change in their ethnic composition, there is a need for regular surveillance of diseases that have previously shown some health disparities. Earlier data have al...

    Authors: Aman PK Nijjar, Hong Wang, Hude Quan and Nadia A Khan

    Citation: BMC Cardiovascular Disorders 2010 10:38

    Content type: Research article

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  20. Blood pressure (BP) lowering in people who have had a stroke or transient ischaemic attack (TIA) leads to reduced risk of further stroke. However, it is not clear what the target BP should be, since intensific...

    Authors: Kate Fletcher, Jonathan Mant, Richard McManus, Sarah Campbell, Jonathan Betts, Clare Taylor, Satnam Virdee, Sue Jowett, Una Martin, Sheila Greenfield, Gary Ford, Nick Freemantle and FD Richard Hobbs

    Citation: BMC Cardiovascular Disorders 2010 10:37

    Content type: Study protocol

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  21. Lower extremity peripheral arterial disease (PAD) is a marker of widespread atherosclerosis. Individuals with PAD, most of whom do not show typical PAD symptoms ('asymptomatic' patients), are at increased risk...

    Authors: Claudio Cimminiello, Claudio Borghi, Serge Kownator, Jean Claude Wautrecht, Christos P Carvounis, Stefanus E Kranendonk, Beat Kindler and Mario Mangrella

    Citation: BMC Cardiovascular Disorders 2010 10:35

    Content type: Study protocol

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  22. The syndrome of vital exhaustion (VE), characterized by fatigue and irritability, may contribute to an increased risk of atherosclerosis. The aim of the study was to explore sex differences in the interactions...

    Authors: Nadja Chumaeva, Mirka Hintsanen, Markus Juonala, Olli T Raitakari and Liisa Keltikangas-Järvinen

    Citation: BMC Cardiovascular Disorders 2010 10:34

    Content type: Research article

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  23. Moxibustion is a traditional East Asian medical therapy that uses the heat generated by burning herbal preparations containing Artemisia vulgaris to stimulate acupuncture points. The aim of this review was to eva...

    Authors: Jong-In Kim, Jun-Yong Choi, Hyangsook Lee, Myeong Soo Lee and Edzard Ernst

    Citation: BMC Cardiovascular Disorders 2010 10:33

    Content type: Research article

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  24. Heart failure with preserved left ventricular ejection fraction and abnormal diastolic function is commonly observed after recovery from an acute myocardial infarction. The aim of this study was to investigate...

    Authors: Myrielle Mathieu, Bachar El Oumeiri, Karim Touihri, Ielham Hadad, Maryam Mahmoudabady, Philippe Thoma, Thierry Metens, Jozef Bartunek, Guy R Heyndrickx, Serge Brimioulle, Robert Naeije and Kathleen Mc Entee

    Citation: BMC Cardiovascular Disorders 2010 10:32

    Content type: Research article

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  25. To analyze the in-hospital complication rate in women suffering from non-ST elevation myocardial infarction treated with percutaneous coronary intervention (PCI) compared to men.

    Authors: Caroline Berthillot, Dominique Stephan, Michel Chauvin and Gerald Roul

    Citation: BMC Cardiovascular Disorders 2010 10:31

    Content type: Research article

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  26. Development of experimental animal models has played an important role in understanding the mechanisms of cardiac memory. The purpose of this study was to evaluate a new canine model of cardiac memory using en...

    Authors: Li Yue-Chun, Ge Li-Sha, Guang Xue-Qiang, Chen Peng, Wu Lian-Pin, Yang Peng-Lin, Tang Ji-Fei and Lin Jia-Feng

    Citation: BMC Cardiovascular Disorders 2010 10:30

    Content type: Research article

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  27. Prior studies have found that patients taking single-pill amlodipine/atorvastatin (SPAA) have greater likelihood of adherence at 6 months than those taking 2-pill calcium-channel blocker and statin combination...

    Authors: Richard H Chapman, Jason Yeaw and Craig S Roberts

    Citation: BMC Cardiovascular Disorders 2010 10:29

    Content type: Research article

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  28. Resting conventional 12-lead ECG has low sensitivity for detection of coronary artery disease (CAD) and left ventricular hypertrophy (LVH) and low positive predictive value (PPV) for prediction of left ventric...

    Authors: Todd T Schlegel, Walter B Kulecz, Alan H Feiveson, E Carl Greco, Jude L DePalma, Vito Starc, Bojan Vrtovec, M Atiar Rahman, Michael W Bungo, Matthew J Hayat, Terry Bauch, Reynolds Delgado, Stafford G Warren, Tulio Núñez-Medina, Rubén Medina, Diego Jugo…

    Citation: BMC Cardiovascular Disorders 2010 10:28

    Content type: Research article

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  29. Face-to-face outpatient cardiac rehabilitation (OCR) programs are an important and effective component in the management of cardiovascular disease. However, these programs have low participation rates, especia...

    Authors: Corneel Vandelanotte, Trudy Dwyer, Anetta Van Itallie, Christine Hanley and W Kerry Mummery

    Citation: BMC Cardiovascular Disorders 2010 10:27

    Content type: Research article

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  30. We sought to determine the difference in the localization of coronary artery disease (CAD) between the left and right coronary artery system and investigate the effect of sex and age on that difference.

    Authors: George D Giannoglou, Antonios P Antoniadis, Yiannis S Chatzizisis and George E Louridas

    Citation: BMC Cardiovascular Disorders 2010 10:26

    Content type: Research article

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  31. The global burden of cardiovascular disease (CVD) continues to rise. Successful treatment of CVD requires adequate pharmaceutical management. The aim was to examine the availability, pricing and affordability ...

    Authors: Maaike SM van Mourik, Alexandra Cameron, Marg Ewen and Richard O Laing

    Citation: BMC Cardiovascular Disorders 2010 10:25

    Content type: Research article

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  32. Multiple randomized controlled trials (RCTs) have examined the cardiovascular effects of omega-3 fatty acids and have provided unexplained conflicting results. A meta-analysis of these RCTs to estimate efficac...

    Authors: Kristian B Filion, Fouad El Khoury, Michael Bielinski, Ian Schiller, Nandini Dendukuri and James M Brophy

    Citation: BMC Cardiovascular Disorders 2010 10:24

    Content type: Research article

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  33. Genotype-phenotype association studies are typically based upon polymorphisms or haplotypes comprised of multiple polymorphisms within a single gene. It has been proposed that combinations of polymorphisms in ...

    Authors: Ines N Hahntow, Gideon Mairuhu, Irene GM van Valkengoed, Richard P Koopmans and Martin C Michel

    Citation: BMC Cardiovascular Disorders 2010 10:23

    Content type: Research article

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  34. Hashimoto's thyroiditis is the most important cause of hypothyroidism. It is a systemic disease that can even affect the cardiovascular system, by accelerating the atherosclerotic process. Aim of this study wa...

    Authors: Marco M Ciccone, Giovanni De Pergola, Maria T Porcelli, Pietro Scicchitano, Pasquale Caldarola, Massimo Iacoviello, Guida Pietro, Francesco Giorgino and Stefano Favale

    Citation: BMC Cardiovascular Disorders 2010 10:22

    Content type: Research article

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  35. Atrial fibrillation (AF) patients with a high risk of stroke are recommended anticoagulation with warfarin. However, the benefit of warfarin is dependent upon time spent within the target therapeutic range (TT...

    Authors: Danielle E Smith, Christian Borg Xuereb, Helen M Pattison, Gregory YH Lip and Deirdre A Lane

    Citation: BMC Cardiovascular Disorders 2010 10:21

    Content type: Study protocol

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  36. Liberation from the ventilator is a difficult task, whereas early echocardiographic indices of weaning readiness are still lacking. The aim of this study was to test whether tricuspid annular plane systolic ex...

    Authors: Vasilios E Papaioannou, Dimitrios A Stakos, Christos K Dragoumanis and Ioannis A Pneumatikos

    Citation: BMC Cardiovascular Disorders 2010 10:20

    Content type: Research article

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  37. Proteolytic degradation of Type I Collagen by proteases may play an important role in remodeling of atherosclerotic plaques, contributing to increased risk of plaque rupture.

    Authors: Natasha Barascuk, Helene Skjøt-Arkil, Thomas C Register, Lise Larsen, Inger Byrjalsen, Claus Christiansen and Morten A Karsdal

    Citation: BMC Cardiovascular Disorders 2010 10:19

    Content type: Research article

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  38. Selection of the right warfarin dose at the outset of treatment is not straightforward, and current evidence is lacking to determine the optimal strategy for initiation of therapy.

    Authors: Carl Heneghan, Sally Tyndel, Clare Bankhead, Yi Wan, David Keeling, Rafael Perera and Alison Ward

    Citation: BMC Cardiovascular Disorders 2010 10:18

    Content type: Research article

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  39. Maintaining a healthy weight and undertaking regular physical activity are important for the secondary prevention of cardiovascular disease (CVD). However, many people with CVD are overweight and insufficientl...

    Authors: Janice Sangster, Susan Furber, Margaret Allman-Farinelli, Marion Haas, Philayrath Phongsavan, Andy Mark and Adrian Bauman

    Citation: BMC Cardiovascular Disorders 2010 10:17

    Content type: Study protocol

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  40. Acute mental stress may contribute to the cardiovascular disease progression via autonomic nervous system controlled negative effects on the endothelium. The joint effects of stress-induced sympathetic or para...

    Authors: Nadja Chumaeva, Mirka Hintsanen, Taina Hintsa, Niklas Ravaja, Markus Juonala, Olli T Raitakari and Liisa Keltikangas-Järvinen

    Citation: BMC Cardiovascular Disorders 2010 10:16

    Content type: Research article

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  41. Aorto-bifemoral bypass (AFB) is commonly performed to treat aorto-iliac disease and a durable long-term outcome is achieved. Most studies documenting beneficial outcomes after AFB have been limited to mortalit...

    Authors: Fernando J Abelha, Miguela Botelho, Vera Fernandes and Henrique Barros

    Citation: BMC Cardiovascular Disorders 2010 10:15

    Content type: Research article

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  42. Bilateral stroke following radiofrequency catheter ablation is an unusual complication and may result in bilateral altitudinal visual field defects. Bilateral altitudinal visual field defects usually result fr...

    Authors: Susie T Luu, Andrew W Lee and Celia S Chen

    Citation: BMC Cardiovascular Disorders 2010 10:14

    Content type: Case report

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  43. Patients with acute coronary syndrome (ACS) in India have increased pre-hospital delay and low rates of thrombolytic reperfusion. Use of ECG could reduce pre-hospital delay among patients who first present to ...

    Authors: Joshua Schulman-Marcus, Dorairaj Prabhakaran and Thomas A Gaziano

    Citation: BMC Cardiovascular Disorders 2010 10:13

    Content type: Research article

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  44. Heart failure (HF) is a major cause of hospitalization and death in the aging population around the world. Home care utilization is associated with improved survival for the patients with HF, and varies by eth...

    Authors: Guanmin Chen, Nadia Khan, Kathryn M King, Brenda R Hemmelgarn and Hude Quan

    Citation: BMC Cardiovascular Disorders 2010 10:12

    Content type: Research article

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  45. Clinical trials comparing thrombectomy devices with conventional percutaneous coronary interventions (PCI) in patients with acute ST elevation myocardial infarction (STEMI) have produced conflicting results. T...

    Authors: Umesh U Tamhane, Stanley Chetcuti, Irfan Hameed, P Michael Grossman, Mauro Moscucci and Hitinder S Gurm

    Citation: BMC Cardiovascular Disorders 2010 10:10

    Content type: Research article

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  46. Pulmonary arterial hypertension (PAH) has witnessed dramatic treatment advances over the past decade. However, with the exception of epoprostenol, data from short-term randomized controlled trials (RCTs) have ...

    Authors: Peter Steele, Geoff Strange, John Wlodarczyk, Brad Dalton, Simon Stewart, Eli Gabbay and Anne Keogh

    Citation: BMC Cardiovascular Disorders 2010 10:9

    Content type: Research article

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  47. To evaluate the influence of heart disease on clinical characteristics, quality of life, use of health resources, and costs of patients with COPD followed at primary care settings under common clinical practic...

    Authors: Javier de Miguel-Díez, Pilar Carrasco-Garrido, Javier Rejas-Gutierrez, Antonio Martín-Centeno, Elena Gobartt-Vázquez, Valentín Hernandez-Barrera, Angel Gil de Miguel and Rodrigo Jimenez-Garcia

    Citation: BMC Cardiovascular Disorders 2010 10:8

    Content type: Research article

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