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  1. Subclinical hypothyroidism (SCH) has recently been acknowledged as an independent risk factor for coronary artery disease (CAD). However, the characteristics of CAD in patients with SCH are not fully understoo...

    Authors: Xin-zhu Zhou, Rui Shi, Jin Wang, Ke Shi, Xi Liu, Yuan Li, Yue Gao, Ying-kun Guo and Zhi-gang Yang
    Citation: BMC Cardiovascular Disorders 2021 21:303
  2. Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple ...

    Authors: Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor and Jennifer L. Strande
    Citation: BMC Cardiovascular Disorders 2021 21:302
  3. Despite significant progress in surgical treatment of hypoplastic left heart syndrome (HLHS), its mortality and morbidity are still high. Little is known about the molecular abnormalities of the syndrome. In t...

    Authors: Xuelan Liu, Honglei Shang, Bin Li, Liyun Zhao, Ying Hua, Kaiyuan Wu, Manman Hu and Taibing Fan
    Citation: BMC Cardiovascular Disorders 2021 21:300
  4. Oral antiplatelet therapy is the cornerstone of treatment for acute myocardial infaction (AMI). However, detailed usage data on oral antiplatelet therapy are lacking.

    Authors: Xiaofang Tang, Lifu Liu, Jingang Yang, Zhan Gao, Xueyan Zhao, Shubin Qiao, Runlin Gao, Zhifang Wang, Jinqing Yuan and Yuejin Yang
    Citation: BMC Cardiovascular Disorders 2021 21:299
  5. Although many studies showed that the risk of congenital heart disease (CHD) was closely related to genetic factors, the exact pathogenesis is still unknown. Our study aimed to comprehensively assess the assoc...

    Authors: Mengting Sun, Tingting Wang, Peng Huang, Jingyi Diao, Senmao Zhang, Jinqi Li, Liu Luo, Yihuan Li, Letao Chen, Yiping Liu, Jianhui Wei, Xinli Song, Xiaoqi Sheng and Jiabi Qin
    Citation: BMC Cardiovascular Disorders 2021 21:298
  6. The impact of acute total occlusion (TO) of the culprit artery in non-ST-segment elevation myocardial infarction (NSTEMI) is not fully established. We aimed to evaluate the clinical and angiographic phenotype ...

    Authors: Michał Terlecki, Wiktoria Wojciechowska, Dariusz Dudek, Zbigniew Siudak, Krzysztof Plens, Tomasz J. Guzik, Tomasz Drożdż, Jan Pęksa, Stanisław Bartuś, Wojciech Wojakowski, Marek Grygier and Marek Rajzer
    Citation: BMC Cardiovascular Disorders 2021 21:297
  7. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Giuseppe Berton, Rocco Cordiano, Fiorella Cavuto, Francesco Bagato, Heba Talat Mahmoud and Mattia Pasquinucci
    Citation: BMC Cardiovascular Disorders 2021 21:296

    The original article was published in BMC Cardiovascular Disorders 2019 19:119

  8. Although systemic lupus erythematosus (SLE) can affect the cardiovascular system in many ways with diverse presentations, a severe cardiogenic shock secondary to SLE myocarditis is infrequently described in th...

    Authors: Jaydeep J. Raval, Christina Rodriguez Ruiz, James Heywood and Jason J. Weiner
    Citation: BMC Cardiovascular Disorders 2021 21:294
  9. Dietary phytochemical index (DPI) is useful and inexpensive method to identify the role of phytochemicals on cardiovascular disease (CVD) risk factors. This study aimed to assess the relationship between DPI a...

    Authors: Saeideh Delshad Aghdam, Fereydoun Siassi, Ensieh Nasli Esfahani, Mostafa Qorbani, Asadollah Rajab, Zahra Sajjadpour, Anahita Bashiri, Maryam Aghayan and Gity Sotoudeh
    Citation: BMC Cardiovascular Disorders 2021 21:293
  10. Despite the advances of potent oral P2Y12 inhibitors, their onset of action is delayed, which might have a negative impact on clinical outcome in patients undergoing percutaneous coronary intervention (PCI). Tria...

    Authors: A. Selvarajah, A. H. Tavenier, W. L. Bor, V. Houben, S. Rasoul, E. Kaplan, K. Teeuwen, S. H. Hofma, E. Lipsic, G. Amoroso, M. A. H. van Leeuwen, J. M. ten Berg, A. W. J. van ‘t Hof and R. S. Hermanides
    Citation: BMC Cardiovascular Disorders 2021 21:292
  11. Few studies have compared bioelectrical body and visceral fat indices with anthropometric measures, or evaluated their optimal cutoffs in relation to hypertension among Asians. We compared the efficiencies of ...

    Authors: Binbin Zhang, Yaqi Fan, Yuxue Wang, Li Zhang, Chunjun Li, Jiangshan He, Pei Guo, Mianzhi Zhang and Minying Zhang
    Citation: BMC Cardiovascular Disorders 2021 21:291
  12. To compare the effect and outcomes of optical coherence tomography (OCT)-guided rotational atherectomy (RA) with intravascular ultrasound (IVUS)-guided RA in the treatment of calcified coronary lesions.

    Authors: Weili Teng, Qi Li, Yuliang Ma, Chengfu Cao, Jian Liu, Hong Zhao, Mingyu Lu, Chang Hou and Weimin Wang
    Citation: BMC Cardiovascular Disorders 2021 21:290
  13. Nationwide data on the prevalence of atrioventricular (AV) block are currently unavailable in China. Thus, we aimed to assess the prevalence and risk factors of AV block among Chinese health examination adults.

    Authors: Ruiqi Shan, Yi Ning, Yuan Ma, Siliang Liu, Jing Wu, Xiaohan Fan, Jun Lv, Bo Wang, Shijun Li and Liming Li
    Citation: BMC Cardiovascular Disorders 2021 21:289
  14. Atrioventricular (AV) delay could affect AV and ventricular synchrony in cardiac resynchronization therapy (CRT). Strategies to optimize AV delay according to optimal AV synchrony (AVopt-AV) or ventricular synchr...

    Authors: Jie Li, Yuegang Wang, Jingting Mai, Shilan Chen, Menghui Liu, Chen Su, Xumiao Chen, Huiling Huang, Yuedong Ma, Chong Feng, Jingzhou Jiang, Jun Liu, Jiangui He, Anli Tang, Yugang Dong, Xiaobo Huang…
    Citation: BMC Cardiovascular Disorders 2021 21:288
  15. Despite the increasing availability of clinical data due to the digitalisation of healthcare systems, data often remain inaccessible due to the diversity of data collection systems. In the Netherlands, Cardiol...

    Authors: Sophie H. Bots, Klaske R. Siegersma, N. Charlotte Onland-Moret, Folkert W. Asselbergs, G. Aernout Somsen, Igor I. Tulevski, Hester M. den Ruijter and Leonard Hofstra
    Citation: BMC Cardiovascular Disorders 2021 21:287
  16. The proper therapeutic management for acute type A aortic intramural hematoma (IMH) is still controversial. The purpose of this study was to compare the outcomes following emergency surgery or conservative tre...

    Authors: Jue Yang, Changjiang Yu, Xin Li, Juntao Kuang, Zerui Chen, Fei Xiao, Tucheng Sun, Miaoxian Fang and Ruixin Fan
    Citation: BMC Cardiovascular Disorders 2021 21:286
  17. Lipoprotein(a) is genetically determined and increasingly recognized as a major risk factor for arteriosclerotic cardiovascular disease. We examined whether plasma lipoprotein(a) concentrations were associated...

    Authors: Shuang Xia, Weida Qiu, Anping Cai, Bo Kong, Lan Xu, Zejia Wu and Liwen Li
    Citation: BMC Cardiovascular Disorders 2021 21:285
  18. Coronary artery disease (CAD) remains one of the leading causes of mortality worldwide and is associated with multiple inherited and environmental risk factors. This study is designed to identify, design, and ...

    Authors: Ioannis S. Vizirianakis, Fani Chatzopoulou, Andreas S. Papazoglou, Efstratios Karagiannidis, Georgios Sofidis, Nikolaos Stalikas, Christos Stefopoulos, Konstantinos A. Kyritsis, Nikolaos Mittas, Nikoleta F. Theodoroula, Aggeliki Lampri, Eleni Mezarli, Anastasios Kartas, Dimitrios Chatzidimitriou, Anna Papa-Konidari, Eleftherios Angelis…
    Citation: BMC Cardiovascular Disorders 2021 21:284

    The Correction to this article has been published in BMC Cardiovascular Disorders 2021 21:309

  19. Current evidence suggests that high sensitivity cardiac troponin-T (hs-cTnT) values differ based on sex, race, age, and kidney function. However, most studies examining the relationship of hs-cTnT and these in...

    Authors: Nathan Kong, Rhys F. M. Chua, Stephanie A. Besser, Louise Heelan, Sandeep Nathan, Thomas F. Spiegel, Xander M. R. van Wijk and Corey E. Tabit
    Citation: BMC Cardiovascular Disorders 2021 21:283
  20. Complicated pathophysiology makes it difficult to identify the prognosis of heart failure with preserved ejection fraction (HFpEF). While plasma osmolality has been reported to have prognostic importance, main...

    Authors: Akito Nakagawa, Yoshio Yasumura, Chikako Yoshida, Takahiro Okumura, Jun Tateishi, Junichi Yoshida, Shunsuke Tamaki, Masamichi Yano, Takaharu Hayashi, Yusuke Nakagawa, Takahisa Yamada, Daisaku Nakatani, Shungo Hikoso and Yasushi Sakata
    Citation: BMC Cardiovascular Disorders 2021 21:281
  21. A high-fat diet can affect lipid metabolism and trigger cardiovascular diseases. A growing body of studies has revealed the HDL-bound miRNA profiles in familial hypercholesterolaemia; in sharp contrast, releva...

    Authors: Guoyuan Sui, Lianqun Jia, Nan Song, Dongyu Min, Si Chen, Yao Wu and Guanlin Yang
    Citation: BMC Cardiovascular Disorders 2021 21:280
  22. Increased D-dimer levels have been shown to correlate with adverse outcomes in various clinical conditions. However, few studies with a large sample size have been performed thus far to evaluate the prognostic...

    Authors: Ying-Wen Lin, Mei Jiang, Xue-biao Wei, Jie-leng Huang, Zedazhong Su, Yu Wang, Ji-yan Chen and Dan-qing Yu
    Citation: BMC Cardiovascular Disorders 2021 21:279
  23. Coronary artery aneurysm (CAA) is an important complication of Kawasaki disease (KD) that is associated with arterial structure damage. However, few studies have examined structural changes in coronary arterie...

    Authors: Tomoya Tsuchihashi, Nobuyuki Kakimoto, Takashi Takeuchi, Tomohiro Suenaga, Takayuki Suzuki, Shoichi Shibuta, Yasushi Ino, Takashi Kubo, Takashi Akasaka and Hiroyuki Suzuki
    Citation: BMC Cardiovascular Disorders 2021 21:278
  24. Previous studies suggested that obesity and fat mass are associated with QT interval prolongation, but the role of different body parts' fat mass is unclear. The associations between total and regional fat mas...

    Authors: Mohammad Hosein Yazdanpanah, Ehsan Bahramali, Mohammad Mehdi Naghizadeh, Mojtaba Farjam, Maryam Mobasheri and Shiva Dadvand
    Citation: BMC Cardiovascular Disorders 2021 21:277
  25. The study aimed to investigate the functional capacity and hemodynamics at rest and during exercise in patients with chronic atrial fibrillation and severe functional symptomatic tricuspid regurgitation (AF-FTR).

    Authors: Jesper K. Jensen, Tor S. Clemmensen, Christian A. Frederiksen, Joachim Schofer, Mads J. Andersen and Steen H. Poulsen
    Citation: BMC Cardiovascular Disorders 2021 21:276
  26. One of the most common causes of death in the world is coronary artery disease (CAD). Estrogen, the most important early sex hormones in women, plays an important role in the risk reduction of cardiovascular d...

    Authors: Farzaneh Foroughinia, Pooyan Dehghani, Mehdi Dianatpour, Arghavan Amiri, Iman Jamhiri and Parisa Ghasemiyeh
    Citation: BMC Cardiovascular Disorders 2021 21:275
  27. The morning blood pressure surge (MBPS) is related to an exaggerated risk of cardiovascular diseases and mortality. With increasing attention on circadian change in blood pressure and extensive use of ambulato...

    Authors: Ziyan Xie, Jiahao Zhang, Chenyu Wang and Xiaowei Yan
    Citation: BMC Cardiovascular Disorders 2021 21:274
  28. Coronary artery-to-pulmonary artery fistula is a rare disorder characterized by abnormal vascular communication between the coronary artery and pulmonary artery. While most patients remain asymptomatic, some m...

    Authors: Xuanqi An, Shaoxian Guo, Huawei Dong, Yida Tang, Lin Li, Xuejing Duan and Shaodong Ye
    Citation: BMC Cardiovascular Disorders 2021 21:273
  29. We evaluated malignancy according to the characteristics of pericardial fluid in symptomatic Japanese patients undergoing pericardiocentesis and computed tomography (CT).

    Authors: Takashi Nakamura, Mana Okune, Masakazu Yasuda, Heitaro Watanabe, Masafumi Ueno, Kenji Yamaji, Kazuki Mizutani, Takashi Kurita and Gaku Nakazawa
    Citation: BMC Cardiovascular Disorders 2021 21:272
  30. Clinical symptoms of patients on dialysis do not match the signs of coronary disease progression, making the prediction of the true progression of their medical condition in clinical settings difficult. Emerge...

    Authors: Hironobu Yamaoka, Taira Yamamoto, Daisuke Endo, Akie Shimada, Satoshi Matsushita, Tohru Asai and Atsushi Amano
    Citation: BMC Cardiovascular Disorders 2021 21:271
  31. This study aimed to determine native T1 and extracellular volume fraction (ECV) in distinct types of myocardial disease, including amyloidosis, dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), ...

    Authors: Rawiwan Thongsongsang, Thammarak Songsangjinda, Prajak Tanapibunpon and Rungroj Krittayaphong
    Citation: BMC Cardiovascular Disorders 2021 21:270
  32. Reduced left ventricular function, assessed by global longitudinal strain (GLS), is sometimes observed in asymptomatic patients with diabetes mellitus (DM) and is often present in patients with diabetes-relate...

    Authors: Gokulan Pararajasingam, Laurits Juhl Heinsen, Johanna Larsson, Thomas Rueskov Andersen, Brian Bridal Løgstrup, Søren Auscher, Jørgen Hangaard, Rasmus Møgelvang and Kenneth Egstrup
    Citation: BMC Cardiovascular Disorders 2021 21:269
  33. ICD patients with episodes of nonsustained ventricular tachycardias (NSVT) are at risk of appropriate therapies. However, the relationship between the cycle length (CL) of such NSVTs and the subsequent inciden...

    Authors: Javier Jiménez-Candil, Olga Duran, Armando Oterino, Jendri Pérez, Juan Carlos Castro, Jesús Hernández, José Moríñigo, Manuel Sánchez García and Pedro L. Sánchez
    Citation: BMC Cardiovascular Disorders 2021 21:268
  34. Cardiovascular diseases have become the leading cause of death worldwide, and cardiac hypertrophy is the core mechanism underlying cardiac defect and heart failure. However, the underlying mechanisms of cardia...

    Authors: Yi Wang, Hongjuan Liao, Yueheng Wang, Jinlin Zhou, Feng Wang, Yingxin Xie, Kun Zhao and Weinian Gao
    Citation: BMC Cardiovascular Disorders 2021 21:266
  35. The left atrial (LA) strain and strain rate are sensitive indicators of LA function. However, they are not widely used for the evaluation of pregnant women with metabolic diseases. The aim of this study was to...

    Authors: Xiaoguang Ye, Zhitian Li, Yidan Li, Qizhe Cai, Lanlan Sun, Weiwei Zhu, Xueyan Ding, Dichen Guo, Yunyun Qin and Xiuzhang Lu
    Citation: BMC Cardiovascular Disorders 2021 21:265
  36. Soluble suppression of tumorigenesis-2 (sST2), Procollagen Type III N-Terminal Peptid (PIIINP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) have been verified their role in predicting survival in ...

    Authors: Yiling Yao, Li Feng, Yanxiang Sun, Shifei Wang, Jie Sun and Bing Hu
    Citation: BMC Cardiovascular Disorders 2021 21:264
  37. Abdominal obesity as a predominant comorbidity has played a key role in the incidence and worsening of heart failure with preserved ejection fraction (HFpEF), and waist-to-height ratio (WHtR) behaves better th...

    Authors: Jianqiao Chen, Man Li, Benchuan Hao, Yulun Cai, Huiying Li, Wenli Zhou, Yujian Song, Shiqi Wang and Hongbin Liu
    Citation: BMC Cardiovascular Disorders 2021 21:263
  38. We examined the relationship between epicardial fat thickness (EFT) measured by echocardiography and left ventricular diastolic function parameters in a Beijing community population.

    Authors: Wei Ma, Baowei Zhang, Ying Yang, Litong Qi, Jin Zhou, Min Li, Jia Jia, Yan Zhang and Huo Yong
    Citation: BMC Cardiovascular Disorders 2021 21:262
  39. In recent years, decreases in mortality rates attributable to cardiovascular diseases have slowed but mortality attributable to heart failure (HF) has increased.

    Authors: Matthew T. Mefford, Zimin Zhuang, Zhi Liang, Wansu Chen, Sandra Y. Koyama, Maria T. Taitano, Heather L. Watson, Ming-Sum Lee, Stephen Sidney and Kristi Reynolds
    Citation: BMC Cardiovascular Disorders 2021 21:261
  40. Cancer associated thrombosis is recognized. However, pulmonary embolism (PE) from testicular cancer is rarely reported. Right ventricular (RV) function and PE are closely related. The RV cannot cope with a sud...

    Authors: Khaled Elenizi, Rasha Alharthi and Michel Galinier
    Citation: BMC Cardiovascular Disorders 2021 21:260
  41. This study examines the socioeconomic differentials in trends in the prevalence of hypertension and pre-hypertension and hypertension awareness, treatment, and control in rural Southwestern China.

    Authors: Lu-Ming Fan, Fang Wang, Min Zhao, Wen-Long Cui and Le Cai
    Citation: BMC Cardiovascular Disorders 2021 21:259
  42. Limited data were available on the current trends in optimal medical therapy (OMT) after PCI and its influence on clinical outcomes in China. We aimed to evaluate the utilization and impact of OMT on the main ...

    Authors: Jian Zhang, Jing-Yan Hao, Rui Jing, Jing-Jing Liu, Cheng-Ye Di, Yu-Jie Lu, Peng Gao, Ya-Jie Wang, Rui-Fei Yang and Wen-Hua Lin
    Citation: BMC Cardiovascular Disorders 2021 21:258
  43. Elevated level of plasma uric acid (PUA) has been associated with cardiovascular disease, but whether uric acid is an independent risk factor or merely a marker remains controversial.

    Authors: Humam Hamid, Venla Kurra, Manoj Kumar Choudhary, Heidi Bouquin, Onni Niemelä, Mika A. P. Kähönen, Jukka T. Mustonen, Ilkka H. Pörsti and Jenni K. Koskela
    Citation: BMC Cardiovascular Disorders 2021 21:257
  44. Hypertensive patients can freely choose informal medical facilities, such as pharmacies, community health service centres, and cardiology clinics in secondary or tertiary hospitals, as routine places for medic...

    Authors: Si Wang, Kai Liu, Xin Zhang, Qingtao Meng, Xinran Li, Runyu Ye, Zhipeng Zhang and Xiaoping Chen
    Citation: BMC Cardiovascular Disorders 2021 21:256
  45. Several studies have illustrated the use of echocardiography, magnetic resonance imaging, and nuclear imaging to optimize left ventricular (LV) lead placement to enhance the response of cardiac resynchronizati...

    Authors: Xiao Hu, Hai Xu, Shameer Raaj Avishkar Hassea, Zhiyong Qian, Yao Wang, Xinwei Zhang, Xiaofeng Hou and Jiangang Zou
    Citation: BMC Cardiovascular Disorders 2021 21:255
  46. Dipping of blood pressure (BP) at night is a normal physiological phenomenon. However, a non-dipping pattern is associated with hypertension mediated organ damage, secondary forms of hypertension and poorer lo...

    Authors: Prossie Merab Ingabire, Dike B. Ojji, Brian Rayner, Elijah Ogola, Albertino Damasceno, Erika Jones, Anastase Dzudie, Okechukwu S. Ogah, Neil Poulter, Mahmoud U. Sani, Felix Ayub Barasa, Grace Shedul, John Mukisa, David Mukunya, Bonnie Wandera, Charles Batte…
    Citation: BMC Cardiovascular Disorders 2021 21:254
  47. Accurate prediction of major adverse cardiovascular events (MACEs) is very important for the management of acute coronary syndrome (ACS) patients. We aimed to construct an effective prognostic nomogram for ind...

    Authors: Shuting Kong, Changxi Chen, Gaoshu Zheng, Hui Yao, Junfeng Li, Hong Ye, Xiaobo Wang, Xiang Qu, Xiaodong Zhou, Yucheng Lu and Hao Zhou
    Citation: BMC Cardiovascular Disorders 2021 21:253

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