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Primary Prevention and Cardiovascular Risk

This section also considers articles that address the cause and prevention of cardiovascular disorders such as exercise, physiology, and rehabilitation. Primary prevention studies, in patients at high cardiovascular risk, including those with metabolic syndrome and diabetes, are welcomed.

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  1. This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department.

    Authors: Gil Bonet, Anna Carrasquer, Óscar M. Peiró, Raul Sanchez-Gimenez, Nisha Lal-Trehan, Victor del-Moral-Ronda, Isabel Fort-Gallifa and Alfredo Bardají

    Citation: BMC Cardiovascular Disorders 2021 21:414

    Content type: Research article

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  2. Congenital heart disease (CHD) accounts for nearly a third of all major congenital anomalies. Advances in pediatric cardiology shifted attention from mortality to morbidity and health-related quality of life (...

    Authors: Teresa Grimaldi Capitello, Francesca Bevilacqua, Roberta Vallone, Anna Maria Dall’Oglio, Francesca Santato, Salvatore Giannico, Giulio Calcagni, Simone Piga, Marta Ciofi degli Atti, Simonetta Gentile and Angela Rossi

    Citation: BMC Cardiovascular Disorders 2021 21:398

    Content type: Research article

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  3. Half of U.S. adults have received at least one dose of the COVID-19 vaccines produced by either Pfizer, Moderna, or Johnson and Johnson, which represents a major milestone in the ongoing pandemic. Given the em...

    Authors: Ammar A. Hasnie, Usman A. Hasnie, Nirav Patel, Muhammad U. Aziz, Min Xie, Steven G. Lloyd and Sumanth D. Prabhu

    Citation: BMC Cardiovascular Disorders 2021 21:375

    Content type: Case report

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  4. As the burden of cardiovascular disease increases in sub-Saharan Africa, there is a growing need for low-cost interventions to mitigate its impact. Providing self-care health education to patients with chronic...

    Authors: Getenet Dessie, Sahai Burrowes, Henok Mulugeta, Dessalegn Haile, Ayenew Negess, Dubie Jara, Girma Alem, Bekele Tesfaye, Haymanot Zeleke, Tenaw Gualu, Temsgen Getaneh, Getiye Dejenu Kibret, Desalegne Amare, Endalkachew Worku Mengesha, Fasil Wagnew and Rasheda Khanam

    Citation: BMC Cardiovascular Disorders 2021 21:374

    Content type: Research article

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  5. Atrial fibrillation (AF) is the most common cardiac arrhythmia in patients with chronic kidney disease (CKD) and acute coronary syndrome (ACS). This study aimed to explore the frequency and impact of AF on cli...

    Authors: Lijiao Yang, Nan Ye, Guoqin Wang, Weijing Bian, Fengbo Xu, Dong Zhao, Jing Liu, Yongchen Hao, Jun Liu, Na Yang and Hong Cheng

    Citation: BMC Cardiovascular Disorders 2021 21:345

    Content type: Research article

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  6. Health systems are increasingly using standardized social needs screening and response protocols including the Protocol for Responding to and Assessing Patients’ Risks, Assets, and Experiences (PRAPARE) to imp...

    Authors: Connor Drake, Tyler Lian, Justin G. Trogdon, David Edelman, Howard Eisenson, Morris Weinberger, Kristin Reiter and Christopher M. Shea

    Citation: BMC Cardiovascular Disorders 2021 21:342

    Content type: Research article

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  7. Cardiovascular disease (CVD) is the leading cause of death among non-communicable diseases in South Africa. Several metabolic risk factors contribute to the development of CVD. Informal workers such as waste p...

    Authors: Felix Made, Engelbert A. Nonterah, Nonhlanhla Tlotleng, Vusi Ntlebi and Nisha Naicker

    Citation: BMC Cardiovascular Disorders 2021 21:336

    Content type: Research article

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  8. Recently, we face a surge in the fast-forward Coronavirus Disease 2019 (COVID-19) pandemic with nearly 170 million confirmed cases and almost 3.5 million confirmed deaths at the end of May 2021. Obesity, also ...

    Authors: Jacek Bil and Olga Możeńska

    Citation: BMC Cardiovascular Disorders 2021 21:332

    Content type: Commentary

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  9. Little is known about the clinical value of Insulin-like growth factor-binding protein-7 (IGFBP7), a cellular senescence marker, in an elderly general population with multiple co-morbidities and high prevalenc...

    Authors: Jennifer M. T. A. Meessen, Giulia Cesaroni, Gian F. Mureddu, Alessandro Boccanelli, Ursula-Henrike Wienhues-Thelen, Peter Kastner, Luisa Ojeda-Fernandez, Deborah Novelli, Gianfranco Bazzoni, Maurizio Mangiavacchi, Nera Agabiti, Serge Masson, Lidia Staszewsky and Roberto Latini

    Citation: BMC Cardiovascular Disorders 2021 21:328

    Content type: Research article

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  10. The relative association between cardiovascular (CV) risk factors, such as diabetes and hypertension, established CV disease (CVD), and susceptibility to CV complications or mortality in COVID-19 remains unclear.

    Authors: Kevin O’Gallagher, Anthony Shek, Daniel M. Bean, Rebecca Bendayan, Alexandros Papachristidis, James T. H. Teo, Richard J. B. Dobson, Ajay M. Shah and Rosita Zakeri

    Citation: BMC Cardiovascular Disorders 2021 21:327

    Content type: Research article

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  11. The risk of cardiovascular diseases (CVDs) is becoming more prevalent in pregnant women though not much data is available for pregnant women with human immunodeficiency virus (HIV). Foetoplacental vascular end...

    Authors: Benedicta Ngwenchi Nkeh-Chungag, Godwill Azeh Engwa, Charles Businge, Mziwohlanga Mdondolo, Magdevy Pajaro Medina and Nandu Goswami

    Citation: BMC Cardiovascular Disorders 2021 21:322

    Content type: Study protocol

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  12. Reduced left ventricular function, assessed by global longitudinal strain (GLS), is sometimes observed in asymptomatic patients with diabetes mellitus (DM) and is often present in patients with diabetes-relate...

    Authors: Gokulan Pararajasingam, Laurits Juhl Heinsen, Johanna Larsson, Thomas Rueskov Andersen, Brian Bridal Løgstrup, Søren Auscher, Jørgen Hangaard, Rasmus Møgelvang and Kenneth Egstrup

    Citation: BMC Cardiovascular Disorders 2021 21:269

    Content type: Research article

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  13. We examined the relationship between epicardial fat thickness (EFT) measured by echocardiography and left ventricular diastolic function parameters in a Beijing community population.

    Authors: Wei Ma, Baowei Zhang, Ying Yang, Litong Qi, Jin Zhou, Min Li, Jia Jia, Yan Zhang and Huo Yong

    Citation: BMC Cardiovascular Disorders 2021 21:262

    Content type: Research article

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  14. In‐hospital cardiac arrest (IHCA) is a major public health problem with significant mortality. Rapid cardiopulmonary resuscitation and early defibrillation is extremely connected to patient outcome. In this st...

    Authors: G. Spinelli, E. Brogi, A. Sidoti, N. Pagnucci and F. Forfori

    Citation: BMC Cardiovascular Disorders 2021 21:195

    Content type: Research article

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  15. The association of infective endocarditis (IE) with spondylodiscitis (SD) was first reported in 1965, but few data are available about this issue. This study aimed to evaluate the prevalence of SD in patients ...

    Authors: Stefano Del Pace, Valentina Scheggi, Giacomo Virgili, Sabina Caciolli, Iacopo Olivotto, Nicola Zoppetti, Irene Merilli, Nicole Ceschia, Valentina Andrei, Bruno Alterini, Pier Luigi Stefàno and Niccolò Marchionni

    Citation: BMC Cardiovascular Disorders 2021 21:186

    Content type: Research article

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  16. Anthracyclines and monoclonal antibodies against human epidermal growth factor receptor-2 (HER2) are frequently used to treat breast cancer but they are associated with risk of developing cardiotoxicity. Imple...

    Authors: Estíbaliz Díaz-Balboa, Violeta González-Salvado, Beatriz Rodríguez-Romero, Amparo Martínez-Monzonís, Milagros Pedreira-Pérez, Patricia Palacios-Ozores, Rafael López-López, Carlos Peña-Gil and José R. González-Juanatey

    Citation: BMC Cardiovascular Disorders 2021 21:165

    Content type: Study protocol

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  17. Alterations in levels of circulating micro-RNAs might reflect within organ signaling or subclinical tissue injury that is linked to risk of diabetes and cardiovascular risk. We previously found that serum leve...

    Authors: Widet Gallo, Filip Ottosson, Cecilia Kennbäck, Amra Jujic, Jonathan Lou S. Esguerra, Lena Eliasson and Olle Melander

    Citation: BMC Cardiovascular Disorders 2021 21:162

    Content type: Research article

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  18. The BMI index cannot always be used in people with intellectual disabilities due to neuromuscular coordination disorders and psychological barriers that may hinder conventional body weight measurement. The stu...

    Authors: Anna Zwierzchowska, Diana Celebańska, Barbara Rosołek, Krystyna Gawlik and Aleksandra Żebrowska

    Citation: BMC Cardiovascular Disorders 2021 21:119

    Content type: Research article

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  19. The serum hemoglobin (Hb) level is closely related to adverse clinical outcomes. However, data on the association of Hb levels with subclinical atherosclerosis beyond metabolic abnormalities are limited.

    Authors: Yunsuk Choi, Ki-Bum Won, Hyeon Hui Kang and Hyuk-Jae Change

    Citation: BMC Cardiovascular Disorders 2021 21:35

    Content type: Research article

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  20. Observational studies suggest that early menopause is associated with increased risk of death and cardiovascular disease (CVD); however, the results of these studies have been inconsistently. We aimed to asses...

    Authors: Yan Li, Dong Zhao, Miao Wang, Jia-yi Sun, Jun Liu, Yue Qi, Yong-chen Hao, Qiu-ju Deng, Jue Liu, Jing Liu and Min Liu

    Citation: BMC Cardiovascular Disorders 2021 21:109

    Content type: Research article

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  21. To investigate the ability of body shape index (ABSI), body roundness index (BRI), waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), and body adiposity in...

    Authors: Jinjian Xu, Liqun Zhang, Qiong Wu, Yaohan Zhou, Ziqi Jin, Zhijian Li and Yimin Zhu

    Citation: BMC Cardiovascular Disorders 2021 21:97

    Content type: Research article

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  22. This study aimed to examine the relationship between oral health status and hygiene behavior among adults and elderly with preceding chronic disease or coronary artery disease history.

    Authors: Sun Kyung Lee and Seon Young Hwang

    Citation: BMC Cardiovascular Disorders 2021 21:71

    Content type: Research article

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  23. Worldwide cardiovascular disease is the major cause of disability and premature death. This is due to the ascending trend of consuming an unhealthy diet and obesity which increases the risk of hypertension and...

    Authors: Dessie Abebaw Angaw, Rahma Ali, Afework Tadele and Shegaye Shumet

    Citation: BMC Cardiovascular Disorders 2021 21:37

    Content type: Research article

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  24. High and low levels of serum alanine aminotransferase (ALT) are both associated with cardiovascular diseases (CVD) risks especially in elderly, but the mechanisms are less known. This study investigated associ...

    Authors: Svein Ivar Bekkelund

    Citation: BMC Cardiovascular Disorders 2021 21:29

    Content type: Research article

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  25. Mortality in infective endocarditis (IE) is still high, and the long term prognosis remains uncertain. This study aimed to identify predictors of long-term mortality for any cause, adverse event rate, relapse ...

    Authors: Valentina Scheggi, Irene Merilli, Rossella Marcucci, Stefano Del Pace, Iacopo Olivotto, Nicola Zoppetti, Nicole Ceschia, Valentina Andrei, Bruno Alterini, Pier Luigi Stefàno and Niccolò Marchionni

    Citation: BMC Cardiovascular Disorders 2021 21:28

    Content type: Research article

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  26. A high prevalence of cardiovascular risk factors including age, male sex, hypertension, diabetes, and tobacco use, has been reported in patients with Coronavirus disease 2019 (COVID-19) who experienced adverse...

    Authors: Angelo Silverio, Marco Di Maio, Rodolfo Citro, Luca Esposito, Giuseppe Iuliano, Michele Bellino, Cesare Baldi, Giuseppe De Luca, Michele Ciccarelli, Carmine Vecchione and Gennaro Galasso

    Citation: BMC Cardiovascular Disorders 2021 21:23

    Content type: Research article

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  27. Hypercholesterolemia (HC) is an important precursor to many cardiovascular, cerebrovascular, and peripheral vascular diseases. A report conducted by the American Heart Association showed the prevalence of HC t...

    Authors: Jamaan Al-Zahrani, Mamdouh M. Shubair, Sameer Al-Ghamdi, Abdullah A. Alrasheed, Abdulrahman A. Alduraywish, Fayez Saud Alreshidi, Saeed Mastour Alshahrani, Majid Alsalamah, Badr F. Al-Khateeb, Aljawharah Ibraheem Ashathri, Ashraf El-Metwally and Khaled K. Aldossari

    Citation: BMC Cardiovascular Disorders 2021 21:22

    Content type: Research article

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  28. Hyperbilirubinemia after heart valve surgery (HVS) with cardiopulmonary bypass is frequently observed and associated with worse outcomes. We investigated the characteristics and prognosis of patients with seve...

    Authors: Xiaolan Chen, Ming Bai, Lijuan Zhao, Yan Yu, Yuan Yue, Shiren Sun and Xiangmei Chen

    Citation: BMC Cardiovascular Disorders 2021 21:16

    Content type: Research article

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  29. There are differences of opinion about the beneficial or detrimental effects of opium consumption on cardiovascular diseases (CVDs). So, we aimed to study the association between opium use and CVDs.

    Authors: Parvin Khalili, Fatemeh Ayoobi, Maryam Mohamadi, Ahmad Jamalizadeh, Carlo La Vecchia and Ali Esmaeili-nadimi

    Citation: BMC Cardiovascular Disorders 2021 21:2

    Content type: Research article

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  30. Population-based levels of the chronic low-grade systemic inflammation biomarker, C-reactive protein (CRP), vary widely among traditional populations, despite their apparent absence of chronic conditions assoc...

    Authors: Pedro Carrera-Bastos, Maelán Fontes-Villalba, Michael Gurven, Frits A. J. Muskiet, Torbjörn Åkerfeldt, Ulf Lindblad, Lennart Råstam, Johan Frostegård, Yinon Shapira, Yehuda Shoenfeld, Yvonne Granfeldt, Kristina Sundquist and Tommy Jönsson

    Citation: BMC Cardiovascular Disorders 2020 20:524

    Content type: Research article

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  31. The association between different ABO blood groups and mortality of aortic dissection (AD) remains controversial. This study aimed to examine whether different ABO blood groups affect the prognosis of AD.

    Authors: Song Huang, Yequn Chen, Zhaotao Huang, Shiwan Wu, Nianling Xiong, Xiru Huang, Xin Wang, Chang Chen, Bin Wang, Weiping Li, Liangli Hong, Shu Ye and Xuerui Tan

    Citation: BMC Cardiovascular Disorders 2020 20:515

    Content type: Research article

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  32. This study aimed to reveal the association of diabetes mellitus and dialysis-dependent renal failure with the lesion severity and chronic total occlusion (CTO) in patients undergoing femoropopliteal endovascul...

    Authors: Mitsuyoshi Takahara, Yoshimitsu Soga, Masahiko Fujihara, Daizo Kawasaki, Amane Kozuki and Osamu Iida

    Citation: BMC Cardiovascular Disorders 2020 20:514

    Content type: Research article

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  33. The ALDH2 rs671 genetic polymorphism has been linked with cardiovascular diseases (CVDs), but comprehensive epidemiological studies are lacking. An observational, retrospective big data study was carried out to ...

    Authors: Danchen Wang, Yutong Zou, Songlin Yu, Songbai Lin, Honglei Li, Yicong Yin, Ling Qiu, Tengda Xu and Jie Wu

    Citation: BMC Cardiovascular Disorders 2020 20:509

    Content type: Research article

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  34. With the rising number of hip surgeries, simple and cost-effective tools for surgery risk assessment are warranted. The analysis of heart rate variability (HRV) may not only provide critical insights into the ...

    Authors: Regina Csanády-Leitner, Franz J. Seibert, Corinna M. Perchtold-Stefan, Werner Maurer-Ertl, Kathrin Hilgarter and Helmut K. Lackner

    Citation: BMC Cardiovascular Disorders 2020 20:507

    Content type: Research article

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  35. Annually > 10% of patients with atrial fibrillation on oral anticoagulation undergo invasive procedures. Optimal peri-procedural management of anticoagulation, as judged by major bleeding and thromboembolic ev...

    Authors: M. Unverdorben, C. von Heymann, A. Santamaria, M. Saxena, T. Vanassche, J. Jin, P.  Laeis, R. Wilkins, C. Chen and P. Colonna

    Citation: BMC Cardiovascular Disorders 2020 20:504

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2021 21:91

  36. Some studies have reported that nitrate intake from vegetables was inversely associated with many vascular diseases, but few studies have paid attention to the relationship between urinary nitrate and cardiova...

    Authors: Zhuo Wu, Ting Tian, Wang Ma, Wen Gao and Ninghong Song

    Citation: BMC Cardiovascular Disorders 2020 20:498

    Content type: Research article

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  37. Fear of movement (kinesiophobia) after an acute cardiac hospitalization (ACH) is associated with reduced physical activity (PA) and non-adherence to cardiac rehabilitation (CR).

    Authors: P. Keessen, C. H. M. Latour, I. C. D. van Duijvenbode, B. Visser, A. Proosdij, D. Reen and W. J. M. Scholte op Reimer

    Citation: BMC Cardiovascular Disorders 2020 20:495

    Content type: Research article

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  38. Type A acute aortic dissection is a life-threatening disease associated with adverse clinical outcomes. Acute kidney injury (AKI) is common after surgery. However, the relationship between intraoperative blood...

    Authors: Yanli Liu, Yuqiang Shang, Ding Long and Li Yu

    Citation: BMC Cardiovascular Disorders 2020 20:446

    Content type: Research article

    Published on:

  39. We report here on a prospective hospital-based cohort study that investigates predictors of 30-day and 90-day mortality and functional disability among Ugandan stroke patients.

    Authors: Gertrude Namale, Onesmus Kamacooko, Anthony Makhoba, Timothy Mugabi, Maria Ndagire, Proscovia Ssanyu, John Bosco M. Ddamulira, Laetitia Yperzeele, Patrick Cras, Edward Ddumba, Janet Seeley and Robert Newton

    Citation: BMC Cardiovascular Disorders 2020 20:442

    Content type: Research article

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  40. Human immunodeficiency virus (HIV) infection is associated with a greater risk of cardiovascular disease (CVD). HIV infection causes a chronic inflammatory state and increases oxidative stress which can cause ...

    Authors: Pedro Martínez-Ayala, Guillermo Adrián Alanis-Sánchez, Luz Alicia González-Hernández, Monserrat Álvarez-Zavala, Rodolfo Ismael Cabrera-Silva, Jaime Federico Andrade-Villanueva, Karina Sánchez-Reyes, Moisés Ramos-Solano, Diego Alberto Castañeda-Zaragoza, David Cardona-Müller, Sylvia Totsuka-Sutto, Ernesto Cardona-Muñoz and Carlos G. Ramos-Becerra

    Citation: BMC Cardiovascular Disorders 2020 20:440

    Content type: Research article

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  41. Various diets and dietary compounds, through their inflammatory properties, are involved in the pathogenesis of chronic diseases including Cardiovascular Diseases (CVDs). Dietary Inflammatory Index (DII) can e...

    Authors: Azad Ayeneh pour, Mehdi Moradinazar, Mehnoosh Samadi, Behrooz Hamzeh, Farid Najafi, Sheno Karimi, Fakhereh Faraji, Mitra Darbandi and Yahya Pasdar

    Citation: BMC Cardiovascular Disorders 2020 20:434

    Content type: Research article

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  42. The World Health Organization recommends consumption of a minimum of 400 g of fruits and vegetables per day for prevention of cardiovascular disease. Low fruit and vegetable intake is associated with an increa...

    Authors: Sajama Nepali, Anupa Rijal, Michael Hecht Olsen, Craig S. McLachlan, Per Kallestrup and Dinesh Neupane

    Citation: BMC Cardiovascular Disorders 2020 20:425

    Content type: Research article

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  43. Effects of re-supplementation of a cholesterol-enriched diet (CEDrs) on size, cholesterol content and morphology of already existing plaques are not known to date.

    Authors: G. A. Bonaterra, K. Bender, B. Wilhelm, H. Schwarzbach, S. Metz, O. Kelber, D. Weiser, J. Metz and R. Kinscherf

    Citation: BMC Cardiovascular Disorders 2020 20:420

    Content type: Research article

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  44. We previously showed that the 10-year cardiovascular disease (CVD) risk threshold to initiate statins for primary prevention depends on the baseline CVD risk, age, sex, and the incidence of statin-related harm...

    Authors: Henock G. Yebyo, Sofia Zappacosta, Hélène E. Aschmann, Sarah R. Haile and Milo A. Puhan

    Citation: BMC Cardiovascular Disorders 2020 20:418

    Content type: Research article

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  45. Adolescents’ health-related behavior varies from weekday to weekend. Only few studies, however, have examined to which degree such variation will affect markers of cardiometabolic health. Therefore, the primar...

    Authors: Louise Sølund Hansen, Marlene Rosager Lund Pedersen, Jakob Tarp, Anna Bugge, Niels Wedderkopp and Niels Christian Møller

    Citation: BMC Cardiovascular Disorders 2020 20:405

    Content type: Research article

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  46. Determining the risk factors for brachial-ankle pulse wave velocity (baPWV) may help to identify people susceptible to diabetic atherosclerosis and could prevent diabetic macrovascular complications in the ear...

    Authors: Kuo Liu, Junfeng Xu, Lixin Tao, Kun Yang, Yang Sun and Xiuhua Guo

    Citation: BMC Cardiovascular Disorders 2020 20:353

    Content type: Research article

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  47. A key strategy for the primary prevention of cardiovascular disease (CVD) is the use of risk prediction algorithms. We aimed to investigate the predictive ability of SCORE (Systematic COronary Risk Estimation)...

    Authors: Cátia Santos-Ferreira, Rui Baptista, Manuel Oliveira-Santos, José Pereira Moura and Lino Gonçalves

    Citation: BMC Cardiovascular Disorders 2020 20:301

    Content type: Research article

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