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Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Free fatty acids (FFAs) predicted the risk of heart failure (HF) and were elevated in HF with very low left ventricular ejection fraction (LVEF) compared to healthy subjects. The aim of this study was to inves...

    Authors: Ning Zhu, Wenbing Jiang, Yi Wang, Youyang Wu, Hao Chen and Xuyong Zhao

    Citation: BMC Cardiovascular Disorders 2018 18:104

    Content type: Research article

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  2. Preexcitation syndrome is characterized by a dominant delta wave on the baseline electrocardiogram (ECG), resulting from the change in QRS initial vector by the accessory pathway (AP). This study is to explore...

    Authors: Zhaolong Xu, Renguang Liu, Qinghua Chang and Changjun Li

    Citation: BMC Cardiovascular Disorders 2018 18:100

    Content type: Research article

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  3. Aortic regurgitation (AR) is a valvular disease that can lead to systolic heart failure. Treatment options besides cardiac surgery are limited and consequently severe AR is associated with higher mortality and...

    Authors: Bachar El-Oumeiri, Kathleen Mc Entee, Filippo Annoni, Antoine Herpain, Frédéric Vanden Eynden, Pascal Jespers, Guido Van Nooten and Philippe van de Borne

    Citation: BMC Cardiovascular Disorders 2018 18:99

    Content type: Research article

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  4. The anticoagulation of atrial fibrillation catheter ablation during the perioperative stage does matter and should be treated with discretion. We aimed to assess impact of three important genes participating i...

    Authors: Jiao Li, Wenlong Yang, Zhonghui Xie, Kun Yu, Yuhua Chen and Kaijun Cui

    Citation: BMC Cardiovascular Disorders 2018 18:96

    Content type: Research article

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  5. Data on left ventricular (LV) function in patients with neurocardiogenic syncope (NS) is conflicting in adults and lacking in children. The aim of this study was to analyze LV myocardial performance in childre...

    Authors: Kai O. Hensel, Markus Roskopf, Francisca Abellan Schneyder and Andreas Heusch

    Citation: BMC Cardiovascular Disorders 2018 18:87

    Content type: Research article

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  6. Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding. The objective of this study is to determine the relative risk of cardiovascular adverse events or ...

    Authors: Jordi Real, M Catalina Serna, Maria Giner-Soriano, Rosa Forés, Guillem Pera, Esther Ribes, Maite Alzamora, Josep Ramon Marsal, Antonio Heras and Rosa Morros

    Citation: BMC Cardiovascular Disorders 2018 18:85

    Content type: Research article

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  7. Cardiovascular disease (CVD) is a risk factor for cognitive impairment in the elderly. Manifestations of subclinical CVDs can be found in patients with cognitive impairment. The aim of the present study was to...

    Authors: Heng Ma, Jun Yang, Haizhu Xie, Jing Liu, Fang Wang, Xiao Xu, Wei Bai and Kai Lin

    Citation: BMC Cardiovascular Disorders 2018 18:79

    Content type: Research article

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  8. Cardiac resynchronization therapy (CRT) is an established therapy for appropriately selected patients with heart failure. Response to CRT has been heterogeneously defined using both clinical and echocardiograp...

    Authors: Z. Bakos, N. C. Chatterjee, C. Reitan, J. P. Singh and R. Borgquist

    Citation: BMC Cardiovascular Disorders 2018 18:70

    Content type: Research article

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  9. Maximal cardiopulmonary exercise testing (CPX) is the gold-standard for cardiorespiratory fitness assessment in chronic heart failure (CHF) patients. However, high costs, required medical supervision, and safe...

    Authors: Gianni Mazzoni, Biagio Sassone, Giovanni Pasanisi, Jonathan Myers, Simona Mandini, Stefano Volpato, Francesco Conconi, Giorgio Chiaranda and Giovanni Grazzi

    Citation: BMC Cardiovascular Disorders 2018 18:67

    Content type: Research article

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  10. A permanently indwelling filter in the inferior vena cava (IVC) may induce caval thrombosis, which could develop and evolve from an acute to a chronic phase. The differential diagnosis of acute and chronic thr...

    Authors: Liang Chen, Wanyin Shi, Jianping Gu, Xu He and Wensheng Lou

    Citation: BMC Cardiovascular Disorders 2018 18:64

    Content type: Research article

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  11. Small conductance calcium-activated potassium channels (SK channels) play a critical role in action potential repolarization in cardiomyocytes. Recently, the potential anti-arrhythmic effect of metformin in di...

    Authors: Xi Fu, Yilong Pan, Qian Cao, Bin Li, Shuo Wang, Hongjiao Du, Na Duan and Xiaodong Li

    Citation: BMC Cardiovascular Disorders 2018 18:63

    Content type: Research article

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  12. Despite current interest in the unfavorable impact of cardiometabolic index (CMI) and lipid accumulation product (LAP) on diabetes and cardiovascular risk, information regarding the relation of CMI and LAP to ...

    Authors: Haoyu Wang, Yingxian Sun, Zhao Li, Xiaofan Guo, Shuang Chen, Ning Ye, Yichen Tian and Lijun Zhang

    Citation: BMC Cardiovascular Disorders 2018 18:62

    Content type: Research article

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  13. Heart failure (HF), the leading cause of morbidity and mortality in the US, affects 6.6 million adults with an estimated additional 3 million people by 2030. More than 50% of HF patients have heart failure wit...

    Authors: Janet D. Pierce, Diane E. Mahoney, John B. Hiebert, Amanda R. Thimmesch, Francisco J. Diaz, Carol Smith, Qiuhua Shen, Dinesh Pal Mudaranthakam and Richard L. Clancy

    Citation: BMC Cardiovascular Disorders 2018 18:57

    Content type: Study protocol

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  14. Severe aortic stenosis (AS) may lead to acute decompensated heart failure resistant to medical treatment. Here, we report a successful emergent transcatheter aortic valve replacement (TAVR) in a patient presen...

    Authors: Hongju Kim and Jung-Hee Lee

    Citation: BMC Cardiovascular Disorders 2018 18:55

    Content type: Case report

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  15. Recent hypotheses have suggested the pathophysiological role of catecholamines in the evolution of the Takotsubo syndrome (TTS). The extent of cardiac and circulatory compromise dictates the use of some form o...

    Authors: Uzair Ansari, Ibrahim El-Battrawy, Christian Fastner, Michael Behnes, Katherine Sattler, Aydin Huseynov, Stefan Baumann, Erol Tülümen, Martin Borggrefe and Ibrahim Akin

    Citation: BMC Cardiovascular Disorders 2018 18:54

    Content type: Research article

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  16. The wearable cardioverter-defibrillator (WCD) has emerged as a valuable tool to temporarily protect patients at risk for sudden cardiac death (SCD). The aim of this study was to determine the value of the WCD ...

    Authors: Susanne Röger, Stefanie L. Rosenkaimer, Anna Hohneck, Siegfried Lang, Ibrahim El-Battrawy, Boris Rudic, Erol Tülümen, Ksenija Stach, Jürgen Kuschyk, Ibrahim Akin and Martin Borggrefe

    Citation: BMC Cardiovascular Disorders 2018 18:52

    Content type: Research article

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  17. Atrial fibrillation (AF) usually originates from pulmonary veins (PVs) but can also be caused by pulmonary veins outside, such as the coronary sinus (CS), the superior vena cava (SVC), and the ligament of Mars...

    Authors: Shiwei Huang, Binglin Pan, He Zou and Wei Lin

    Citation: BMC Cardiovascular Disorders 2018 18:51

    Content type: Case report

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  18. Spinal cord infarction is an uncommon condition. Anterior cord syndrome present with paraparesis or quadriparesis with sparing of vibration and proprioceptive senses. The common causes of anterior cord syndrom...

    Authors: Nilukshana Yogendranathan, H. M. M. T. B. Herath, W. D. Jayamali, Anne Thushara Matthias, Aruna Pallewatte and Aruna Kulatunga

    Citation: BMC Cardiovascular Disorders 2018 18:48

    Content type: Case report

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  19. Myxomatous mitral valve prolapse is a common cardiac abnormality. Morbus Barlow is characterized by excess myxomatous leaflet tissue, bileaflet prolapse or billowing, chordae elongation and annular dilatation ...

    Authors: S. Gasser, H. Reichenspurner and E. Girdauskas

    Citation: BMC Cardiovascular Disorders 2018 18:41

    Content type: Research article

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  20. Heart Failure (HF) is a low grade inflammatory condition. High sensitivity C-reactive protein (hsCRP) is an established marker of inflammation. A cut-off value of hsCRP beyond which an infection should be soug...

    Authors: Joana Pereira, Ana Ribeiro, João Ferreira-Coimbra, Isaac Barroso, João-Tiago Guimarães, Paulo Bettencourt and Patrícia Lourenço

    Citation: BMC Cardiovascular Disorders 2018 18:40

    Content type: Research article

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  21. To evaluate the possibility of left atrial (LA) remodeling using speckle tracking echocardiography (STE) in patients with interatrial block (IAB).

    Authors: Juan Lacalzada-Almeida, María Manuela Izquierdo-Gómez, Carima Belleyo-Belkasem, Patricia Barrio-Martínez, Javier García-Niebla, Roberto Elosua, Alejandro Jiménez-Sosa, Luis Alberto Escobar-Robledo and Antonio Bayés de Luna

    Citation: BMC Cardiovascular Disorders 2018 18:38

    Content type: Research article

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  22. Oxidative stress has recently been shown to play an important role in the development of arteriosclerosis in patients with Kawasaki disease (KD); however, no study has investigated this association in early ch...

    Authors: Takamichi Ishikawa and Keigo Seki

    Citation: BMC Cardiovascular Disorders 2018 18:30

    Content type: Research article

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  23. Infective endocarditis (IE) is still a condition with high mortality and morbidity, especially in the elderly, and in patients with prosthetic valves. The concept of “time-to-therapy” plays a key role for the ...

    Authors: Alfonso Campanile, Guido Tavazzi, Francesco Caprioglio and Fausto Rigo

    Citation: BMC Cardiovascular Disorders 2018 18:28

    Content type: Case report

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  24. Based on a plenty of different applications, intracardiac echocardiography (ICE) is now a well-established technology in complex electrophysiological procedures. Recently, ICE has become the most widely used u...

    Authors: Marco Zanobini, Antonio Dello Russo, Matteo Saccocci, Sergio Conti, Elisa De Camilli, Giulia Vettor, Valentina Catto, Maurizio Roberto, Cesare Fiorentini, Giuseppe Viale, Claudio Tondo and Michela Casella

    Citation: BMC Cardiovascular Disorders 2018 18:15

    Content type: Case report

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  25. Mortality in patients with acute myocardial infarction (AMI) has improved substantially with modern therapy including percutaneous coronary interventions (PCI) but remains high in certain subgroups such as pat...

    Authors: Grunde Gjesdal, Oscar Ö. Braun, J. Gustav Smith, Fredrik Scherstén and Patrik Tydén

    Citation: BMC Cardiovascular Disorders 2018 18:8

    Content type: Research article

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  26. Metabolic abnormalities in congenital generalized lipodystrophy (CGL) are associated with microvascular complications. However, the evaluation of different types of neuropathy in these patients, including the ...

    Authors: Clarisse Mourão Melo Ponte, Virgínia Oliveira Fernandes, Maria Helane Costa Gurgel, Izabella Tamira Galdino Farias Vasconcelos, Lia Beatriz de Azevedo Souza Karbage, Christiane Bezerra Rocha Liberato, Carlos Antônio Negrato, Marília de Brito Gomes, Ana Paula Dias Rangel Montenegro and Renan Magalhães Montenegro Júnior

    Citation: BMC Cardiovascular Disorders 2018 18:6

    Content type: Research article

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  27. Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survi...

    Authors: Regina Maria de Aquino Xavier, Vitor Manuel Pereira Azevedo, Paulo Henrique Godoy, Arn Migowski, Antonio Luiz Pinho Ribeiro, Rogério Brant Martins Chaves, Marcelo Goulart Correia, Carolina de Aquino Xavier, Lucas de Aquino Hashimoto, Clara Weksler and Nelson Albuquerque Souza e Silva

    Citation: BMC Cardiovascular Disorders 2017 17:302

    Content type: Research article

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  28. Transcatheter aortic valve replacement (TAVR) has been demonstrated to be an established therapy for high-risk, inoperable patients with severe symptomatic aortic valve stenosis. For patients with moderate sur...

    Authors: Joerg Herold, Vasiliki Herold-Vlanti, Mohammad Sherif, Blerim Luani, Christin Breyer, Klaus Bonaventura and Ruediger Braun-Dullaeus

    Citation: BMC Cardiovascular Disorders 2017 17:298

    Content type: Research article

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  29. Takotsubo syndrome, a form of acutely decompensated heart failure, has drawn interest because of its intriguing pathophysiology and therapeutic dilemmas. In their recent work in BMC Cardiovascular Disorders, A...

    Authors: Athanassios Manginas, Angelos G. Rigopoulos, Boris Bigalke, Stefanos Sakellaropoulos, Muhammad Ali, Sophie Mavrogeni and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2017 17:296

    Content type: Correspondence

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  30. Interventional closure of the left atrial appendage (LAA) in patients with non-valvular atrial fibrillation, high thromboembolic and bleeding risk or bleeding history is an alternative therapeutic strategy to ...

    Authors: Blerim Luani, Thomas Groscheck, Conrad Genz, Ivan Tanev, Thomas Rauwolf, Joerg Herold, Senad Medunjanin, Alexander Schmeisser and Rüdiger C. Braun-Dullaeus

    Citation: BMC Cardiovascular Disorders 2017 17:294

    Content type: Research article

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  31. Ganglionated plexuses (GP) are terminal parts of cardiac autonomous nervous system (ANS). Radiofrequency ablation (RFA) for atrial fibrillation (AF) possibly affects GP. Changes in heart rate variability (HRV)...

    Authors: Vilius Kviesulaitis, Aras Puodziukynas, Dainius Haroldas Pauza, Vytautas Zabiela, Tomas Kazakevicius, Raimundas Vaitkevicius, Evaldas Diržinauskas, Vytenis Semaška, Antanas Strazdas, Ruta Unikaite, Kristina Rysevaite, Neringa Pauziene and Remigijus Zaliunas

    Citation: BMC Cardiovascular Disorders 2017 17:292

    Content type: Research article

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  32. Despite advances in medical knowledge, technology and antimicrobial therapy, infective endocarditis (IE) is still associated with devastating outcomes. No reviews have yet assessed the outcomes of IE patients ...

    Authors: Tadesse Melaku Abegaz, Akshaya Srikanth Bhagavathula, Eyob Alemayehu Gebreyohannes, Alemayehu B. Mekonnen and Tamrat Befekadu Abebe

    Citation: BMC Cardiovascular Disorders 2017 17:291

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2018 18:5

  33. Atrial fibrillatory cycle length has been considered one of the indices of atrial electrical remodelling during atrial fibrillation (AF), which can be assessed from surface ECG by computer-assisted calculation...

    Authors: Eva Z. Hesselkilde, Helena Carstensen, Maria M. Haugaard, Jonas Carlson, Steen Pehrson, Thomas Jespersen, Rikke Buhl and Pyotr G. Platonov

    Citation: BMC Cardiovascular Disorders 2017 17:289

    Content type: Research article

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  34. There are still ambiguities existing in regard to left ventricular non-compaction (LVNC) diagnostic imaging. The aim of our study was to analyze diagnostic potential of late gadolinium enhancement (LGE) and ve...

    Authors: Marko Boban, Vladimir Pesa, Ivo Darko Gabric, Sime Manola, Viktor Persic, Helena Antic-Kauzlaric, Marinko Zulj and Aleksandar Vcev

    Citation: BMC Cardiovascular Disorders 2017 17:286

    Content type: Research article

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  35. To investigate the diagnostic value of dual-source computed tomography (DSCT) in the evaluation of tetralogy of Fallot (TOF)-associated extracardiac vascular abnormalities in pediatric patients compared with t...

    Authors: Bi-yue Hu, Ke Shi, Yu-Ping Deng, Kai-Yue Diao, Hua-Yan Xu, Rui Li, Zhi-Gang Yang and Ying-Kun Guo

    Citation: BMC Cardiovascular Disorders 2017 17:285

    Content type: Research article

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  36. The optimal management of chronic severe primary degenerative mitral regurgitation (MR) is to repair the valve but identification of the optimal timing of surgery remains challenging. Current guidelines sugges...

    Authors: Boyang Liu, Nicola C. Edwards, Desley A. H. Neal, Christopher Weston, Gerard Nash, Nicolas Nikolaidis, Thomas Barker, Ramesh Patel, Moninder Bhabra and Richard P. Steeds

    Citation: BMC Cardiovascular Disorders 2017 17:282

    Content type: Study protocol

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  37. Population based studies showed an association of early repolarization in the electrocardiogram (ECG) and a higher rate of sudden cardiac death presumably due to ventricular fibrillation. The triggers for vent...

    Authors: Patrick Badertscher, Michael Kuehne, Beat Schaer, Christian Sticherling, Stefan Osswald and Tobias Reichlin

    Citation: BMC Cardiovascular Disorders 2017 17:277

    Content type: Case report

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  38. Vitamin D status may influence heart failure (HF) patient outcomes by affecting b-type natriuretic peptide (BNP), parathyroid hormone (PTH), and enhancing cardiac contractility. Vitamin D deficiency is associa...

    Authors: Heidi D. Moretti, Vincent J. Colucci and Bradley D. Berry

    Citation: BMC Cardiovascular Disorders 2017 17:274

    Content type: Research article

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  39. The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is the most widely used measure of quality of life (QoL) in HF patients. This prospective study aimed to assess the relationship between QoL and ex...

    Authors: Artan Ahmeti, Michael Y. Henein, Pranvera Ibrahimi, Shpend Elezi, Edmond Haliti, Afrim Poniku, Arlind Batalli and Gani Bajraktari

    Citation: BMC Cardiovascular Disorders 2017 17:268

    Content type: Research article

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  40. Tachyarrhythmia (TA) and bradyarrhythmia (BA) are cardiac rhythm disorders that result in the decline of quality of life. While patients with periodontitis are at a high risk of cardiovascular disease (CVD), l...

    Authors: Norio Aoyama, Jun-ichi Suzuki, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, Hidetoshi Kumagai, Yuichi Ikeda, Hiroshi Akazawa, Issei Komuro, Masato Minabe, Yuichi Izumi and Mitsuaki Isobe

    Citation: BMC Cardiovascular Disorders 2017 17:267

    Content type: Research article

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  41. Takotsubo cardiomyopathy (TCM) is a form of stress-induced cardiomyopathy featured by the dilatation of the apex of the left ventricle during systole. Whereas the pathogenesis of this disorder is not well unde...

    Authors: Chen-Yu C. Guo and Nan-Sung Chou

    Citation: BMC Cardiovascular Disorders 2017 17:266

    Content type: Case report

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  42. Implantable cardioverter defibrillators (ICD) are capable of effectively terminating malignant ventricular arrhythmia and are the most effective way to prevent sudden cardiac death. However, some evidences dem...

    Authors: Ye Zhu, Xiang Gu and Chao Xu

    Citation: BMC Cardiovascular Disorders 2017 17:265

    Content type: Case report

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  43. Non-compaction cardiomyopathy (NCCM) is characterized by prominent trabeculations, deep intertrabecular recesses, and a thick non-compacted endocardial myocardium. Prevalence in the general population remains ...

    Authors: Gustav Mattsson, Abdullah Baroudi, Hoshmand Tawfiq and Peter Magnusson

    Citation: BMC Cardiovascular Disorders 2017 17:263

    Content type: Case report

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  44. One of the most important challenges in public health is to improve the quality of life in patients with chronic heart failure (CHF). Depression, self-care capacity, and quality of life interact each other in ...

    Authors: Qiong Wang, Lini Dong, Zaijin Jian and Xianghua Tang

    Citation: BMC Cardiovascular Disorders 2017 17:262

    Content type: Research article

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  45. Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) carries a risk of sudden death. We aimed to assess whether vectorcardiographic (VCG) parameters directed toward the right heart and a measured...

    Authors: Daniel Cortez, Anneli Svensson, Jonas Carlson, Sharon Graw, Nandita Sharma, Francesca Brun, Anita Spezzacatene, Luisa Mestroni and Pyotr G. Platonov

    Citation: BMC Cardiovascular Disorders 2017 17:261

    Content type: Research article

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  46. Novel anticoagulations (NOACs) are increasingly prescribed for the prevention of stroke in premenopausal women with atrial fibrillation. Small studies suggest NOACs are associated with a higher risk of abnorma...

    Authors: Herbert J. A. Rolden, Angela H. E. M. Maas, Gert Jan van der Wilt and Janneke P. C. Grutters

    Citation: BMC Cardiovascular Disorders 2017 17:260

    Content type: Research article

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  47. There is an increasing trend towards shorter hospital stays after transcatheter aortic valve implantation (TAVI), in particular for patients undergoing the procedure via transfemoral (TF) access. Preliminary d...

    Authors: Marco Barbanti, Jan Baan, Mark S. Spence, Fortunato Iacovelli, Gian Luca Martinelli, Francesco Saia, Alessandro Santo Bortone, Frank van der Kley, Douglas F. Muir, Cameron G. Densem, Marije Vis, Martijn S. van Mourik, Lenka Seilerova, Claudia M. Lüske, Peter Bramlage and Corrado Tamburino

    Citation: BMC Cardiovascular Disorders 2017 17:259

    Content type: Study protocol

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  48. Heart failure (HF) remains a significant cause of morbidity and mortality. Multiple trials over the past several years have examined the effects of both angiotensin-converting enzyme inhibitors (ACEIs) and ang...

    Authors: Chenhui Tai, Tianyi Gan, Liling Zou, Yuxi Sun, Yi Zhang, Wei Chen, Jue Li, Jian Zhang, Yawei Xu, Huihe Lu and Dachun Xu

    Citation: BMC Cardiovascular Disorders 2017 17:257

    Content type: Research article

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