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Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 9

  1. Pulmonary embolism (PE) is associated to high mortality rate worldwide. However, the diagnosis of PE often results inaccurate. Many cases of PE are incorrectly diagnosed or missed and they are often associated...

    Authors: Gelsomina Mansueto, Dario Costa, Emanuele Capasso, Federica Varavallo, Giuseppina Brunitto, Rosanna Caserta, Salvatore Esposito, Massimo Niola, Celestino Sardu, Raffaele Marfella, Claudio Napoli and Mariano Paternoster

    Citation: BMC Cardiovascular Disorders 2019 19:250

    Content type: Research article

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  2. Conventional pharmacologic therapies aim to reduce fluid overload in advanced heart failure (HF) represented by intravenous (IV) loop diuretics (LDs) have sometimes not so efficacious and been reported to have...

    Authors: Ying Yang, Chao Shen, Jiangting Lu, Fen Xu, Jinshan Tong, Jiangfen Jiang and Guosheng Fu

    Citation: BMC Cardiovascular Disorders 2019 19:249

    Content type: Study protocol

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  3. The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued mi...

    Authors: Benjaporn Chinprateep, Nithima Ratanasit, Yodying Kaolawanich, Khemajira Karaketklang, Pairash Saiviroonporn, Vip Viprakasit and Rungroj Krittayaphong

    Citation: BMC Cardiovascular Disorders 2019 19:245

    Content type: Research article

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  4. Care coordination between general practitioners (GPs) and cardiovascular specialists is expected to play a key role in establishing appropriate oral anticoagulant (OAC) treatment in atrial fibrillation (AF) pa...

    Authors: Fumiko Ono, Sayako Akiyama, Akifumi Suzuki, Yoshinobu Ikeda, Akira Takahashi, Hitoshi Matsuoka, Masahiro Sasaki, Tomonori Okamura and Nariaki Yoshihara

    Citation: BMC Cardiovascular Disorders 2019 19:235

    Content type: Research article

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  5. Ventricular arrhythmias (VAs) arising from the origin above pulmonary valve lack comprehensive investigation. This study aimed to disclose the characteristics and radiofrequency catheter ablation (RFCA) outcom...

    Authors: Jin Li, Cheng Zheng, Zhi-Rui Liu, Jun Ma, Ge Jin, Wei-Qian Lin, Yao-Yao Wang and Jia-Feng Lin

    Citation: BMC Cardiovascular Disorders 2019 19:233

    Content type: Research article

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  6. Because of previous ventricular arrhythmia (VA) episodes, patients with implantable cardioverter-defibrillator (ICD) for secondary prevention (SP) are generally considered to have a higher burden of VAs than p...

    Authors: You Zhou, Shuang Zhao, Keping Chen, Wei Hua, Yangang Su, Silin Chen, Zhaoguang Liang, Wei Xu and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:230

    Content type: Research article

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  7. Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Short- and midium-term follow-up data for large samples are limited. This repo...

    Authors: Hao Li, Youyang Shi, Songyue Zhang, Yue Ren, Xing Rong, Zhenquan Wang, Tianhe Xia, Tingting Wu, Haitang Xu, Yaoyao Yan, Yi Zhan, Maoping Chu and Rongzhou Wu

    Citation: BMC Cardiovascular Disorders 2019 19:222

    Content type: Research article

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  8. Patients with reduced ejection fraction have high rates of mortality and readmission after hospitalization for heart failure. In Taiwan, heart failure disease management programs (HFDMPs) have proven effective...

    Authors: Shyh-Ming Chen, Yen-Nan Fang, Lin-Yi Wang, Ming-Kung Wu, Po-Jui Wu, Tsung-Hsun Yang, Yung-Lung Chen and Chi-Ling Hang

    Citation: BMC Cardiovascular Disorders 2019 19:220

    Content type: Research article

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  9. Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac r...

    Authors: Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge Jin, Qing-Qing Wu, Sha-Sha Wang and Yuan Yuan

    Citation: BMC Cardiovascular Disorders 2019 19:219

    Content type: Research article

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  10. Cardiac power output (CPO), derived from the product of cardiac output and mean aortic pressure, is an important yet underexploited parameter for hemodynamic monitoring of critically ill patients in the intens...

    Authors: Dawud Abawi, Alessandro Faragli, Michael Schwarzl, Martin Manninger, David Zweiker, Karl-Patrik Kresoja, Jochen Verderber, Birgit Zirngast, Heinrich Maechler, Paul Steendijk, Burkert Pieske, Heiner Post and Alessio Alogna

    Citation: BMC Cardiovascular Disorders 2019 19:217

    Content type: Research article

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  11. There is limited information regarding left atrial (LA) mechanics in aortic valve stenosis (AS). We assessed LA mechanics in AS through speckle-tracking echocardiography (STE) according to severity and prognosis.

    Authors: Patrícia Marques-Alves, Ana Vera Marinho, Rogério Teixeira, Rui Baptista, Graça Castro, Rui Martins and Lino Gonçalves

    Citation: BMC Cardiovascular Disorders 2019 19:215

    Content type: Research article

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  12. Heart failure (HF) with mid-range ejection fraction (EF) (HFmrEF) has attracted increasing attention in recent years. However, the understanding of HFmrEF remains limited, especially among Asian patients. Ther...

    Authors: Siqi Lyu, Litian Yu, Huiqiong Tan, Shaoshuai Liu, Xiaoning Liu, Xiao Guo and Jun Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:209

    Content type: Research article

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  13. Colchicine has been used as anti-inflammatory agent in pericardial effusion (PE). We sought to perform a meta-analysis of randomized trials assessing the efficacy and safety of colchicine in patients with peri...

    Authors: Leon L. Lutschinger, Angelos G. Rigopoulos, Peter Schlattmann, Marios Matiakis, Daniel Sedding, Paul Christian Schulze and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2019 19:207

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:227

  14. Cellular therapies have been increasingly applied to diverse human diseases. Intracoronary infusion of bone marrow-derived mononuclear cells (BMMNC) has demonstrated to improve ventricular function after acute...

    Authors: Miguel Romero, José Suárez-de-Lezo, Concha Herrera, Manuel Pan, José López-Aguilera, José Suárez-de-Lezo Jr, Flor Baeza-Garzón, Francisco Javier Hidalgo-Lesmes, Olga Fernández-López, Juliana Martínez-Atienza, Eva Cebrián, Vanesa Martín-Palanco, Rosario Jiménez-Moreno, Rosario Gutiérrez-Fernández, Sonia Nogueras, Maria Dolores Carmona…

    Citation: BMC Cardiovascular Disorders 2019 19:203

    Content type: Study protocol

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  15. Pregnancy-associated Venous thromboembolism (VTE) is one of the most common causes of maternal morbidity and mortality in developed countries. In this study, we aimed to systematically review and critical appr...

    Authors: Jie Zheng, Qinchang Chen, Jing Fu, Yanling Lu, Tianjun Han and Ping He

    Citation: BMC Cardiovascular Disorders 2019 19:199

    Content type: Research article

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  16. Cardiac pacing is a growing activity in Sub-Saharan Africa. There is little data on the characteristics of this interventional treatment in our regions. The goal was to evaluate the results of cardiac pacing i...

    Authors: Adama Kane, Simon Antoine Sarr, Juliette Valerie Danièle Ndobo, Alioune Tabane, Kana Babaka, Fatou Aw, Malick Bodian, Serigne Mor Beye, Momar Dioum, Aliou Alassane Ngaidé, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Maboury Diao, Abdoul Kane and Serigne Abdou BA

    Citation: BMC Cardiovascular Disorders 2019 19:197

    Content type: Research article

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  17. Left atrial appendage closure is increasingly used. LAA closure procedures can rarely be complicated by device embolization, typically towards the aorta. In this case report, we describe the successful percuta...

    Authors: Manik Chopra, Yam-Hong Wong, Lars Søndergaard and Ole De Backer

    Citation: BMC Cardiovascular Disorders 2019 19:196

    Content type: Case report

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  18. In patients with cardiac resynchronization therapy (CRT), atrial fibrillation (AF) is associated with an unfavorable outcome and may cause loss of biventricular pacing (BivP). An effective delivery of BivP of ...

    Authors: Jonatan Jacobsson, Christian Reitan, Jonas Carlson, Rasmus Borgquist and Pyotr G. Platonov

    Citation: BMC Cardiovascular Disorders 2019 19:195

    Content type: Research article

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  19. Mineralocorticoid receptor antagonists (MRA) are an underutilized therapy for heart failure with a reduced ejection fraction (HFrEF), but the current impact of hospitalization on MRA use is not well characteri...

    Authors: Matthew S. Durstenfeld, Stuart D. Katz, Hannah Park and Saul Blecker

    Citation: BMC Cardiovascular Disorders 2019 19:194

    Content type: Research article

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  20. Swallow or deglutition syncope is an unusual type of neurally-mediated syncope associated with life-threatening bradyarrhythmia and hypotension. It is a difficult condition to diagnose with commonly delayed di...

    Authors: Kelvin Shenq Woei Siew, Maw Pin Tan, Ida Normiha Hilmi and Alexander Loch

    Citation: BMC Cardiovascular Disorders 2019 19:191

    Content type: Case report

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  21. The development of novel oral anticoagulants (NOACs) has changed the landscape of non-valvular atrial fibrillation (NVAF) management. In this study, the effectiveness and the safety of several NOACs were evalu...

    Authors: Jianchao Zhang, Junnan Tang, Xiaolin Cui, Bo Wang, Mengsen Bu, Yan Bai, Kai Wang, Jiacheng Guo, Deliang Shen and Jinying Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:182

    Content type: Research article

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  22. Considering vital role of renal arteries in many surgical procedures, diameter of renal arteries seems to be an important measure of kidney perfusion. In this study, we analyzed a new parameter, renal-aortic r...

    Authors: Marcin Majos, Michał Polguj, Ludomir Stefańczyk, Magdalena Derlatka-Kochel, Mariusz Wachowski and Agata Majos

    Citation: BMC Cardiovascular Disorders 2019 19:181

    Content type: Research article

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  23. We aimed to determine the mutation yield and clinical applicability of “molecular autopsy” following sudden arrhythmic death syndrome (SADS) by validating and utilizing low-cost high-throughput technologies: F...

    Authors: Hariharan Raju, James S. Ware, Jonathan R. Skinner, Paula L. Hedley, Gavin Arno, Donald R. Love, Christian van der Werf, Jacob Tfelt-Hansen, Bo Gregers Winkel, Marta C. Cohen, Xinzhong Li, Shibu John, Sanjay Sharma, Steve Jeffery, Arthur A. M. Wilde, Michael Christiansen…

    Citation: BMC Cardiovascular Disorders 2019 19:174

    Content type: Research article

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  24. Anthracyclines are highly effective anticancer medication prescribed for the treatment of breast cancer. Nevertheless, the use of anthracyclines as chemotherapeutic agents involves a risk for development of ca...

    Authors: Jock Chichaco Kuruc, Armando A. Durant-Archibold, Jorge Motta, K. S. Rao, Barry Trachtenberg, Carlos Ramos, Hongyu Wang, David Gorenstein, Fredrik Vannberg and King Jordan

    Citation: BMC Cardiovascular Disorders 2019 19:169

    Content type: Case report

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  25. Non-vitamin K antagonist (VKA) oral anticoagulants (NOACs) have substantially improved anticoagulation therapy for prevention of stroke and systemic embolism in patients with atrial fibrillation (AF). The avai...

    Authors: Raffaele De Caterina, Peter Kelly, Pedro Monteiro, Jean Claude Deharo, Carlo de Asmundis, Esteban López-de-Sá, Thomas W. Weiss, Johannes Waltenberger, Jan Steffel, Joris R. de Groot, Pierre Levy, Ameet Bakhai, Wolfgang Zierhut, Petra Laeis, Michael Kerschnitzki, Paul-Egbert Reimitz…

    Citation: BMC Cardiovascular Disorders 2019 19:165

    Content type: Research article

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  26. Atrial fibrillation (AF) and related atrial tachyarrhythmias (AT), including type I atrial flutter (AFL) are frequently observed in patients with pulmonary hypertension (PH). Their relationship to hemodynamic ...

    Authors: Zdenka Fingrova, Stepan Havranek, David Ambroz, Pavel Jansa and Ales Linhart

    Citation: BMC Cardiovascular Disorders 2019 19:157

    Content type: Research article

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  27. Continuous-flow left ventricular assist devices (LVADs) improve survival and morbidity in patients with stage D heart failure. Management of LVADs for longer durations is necessary in some clinical settings, a...

    Authors: Chie Bujo, Eisuke Amiya, Masaru Hatano, Masaki Tsuji, Hisataka Maki, Yumiko Hosoya, Emi Fujii, Tatsuya Kamon, Toshiya Kojima, Kan Nawata, Osamu Kinoshita, Mitsutoshi Kimura, Minoru Ono and Issei Komuro

    Citation: BMC Cardiovascular Disorders 2019 19:151

    Content type: Case report

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  28. Little is known about the ICD performance using enhanced detection algorithms in unselected, non-trial patients. Performance of recent generation ICD equipped with SmartShock™ technology (SST) for detection an...

    Authors: François Regoli, Denis Graf, Beat Schaer, Firat Duru, Peter Ammann, Lorenza Mangoni di S. Stefano, Barbara Naegli, Haran Burri, Rainer Zbinden, Nazmi Krasniqi and Martin Fromer

    Citation: BMC Cardiovascular Disorders 2019 19:146

    Content type: Research article

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  29. Clinical trials have demonstrated that direct oral anticoagulants (DOACs) are at least non-inferior to warfarin in reducing the risk of stroke/systemic embolism (SE) among patients with non-valvular atrial fib...

    Authors: Kiran Gupta, Jeffrey Trocio, Allison Keshishian, Qisu Zhang, Oluwaseyi Dina, Jack Mardekian, Anagha Nadkarni and Thomas C Shank

    Citation: BMC Cardiovascular Disorders 2019 19:142

    Content type: Research article

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  30. Catheter ablation (CA) and left atrial appendage closure (LAAC) have been combined into a novel one-stop procedure for patients with atrial fibrillation (AF). However, postoperative complications are relativel...

    Authors: Zhonglin Han, Xiang Wu, Zheng Chen, Wengqing Ji, Xuehua Liu, Yu Liu, Wencheng Di, Xiaohong Li, Hongsong Yu, Xinlin Zhang, Biao Xu, Rong Fang Lan and Wei Xu

    Citation: BMC Cardiovascular Disorders 2019 19:138

    Content type: Research article

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  31. Historically, the majority of insertable cardiac monitor (ICM) procedures were performed in the cardiac catheterization (cath) lab, electrophysiology (EP) lab, or operating room (OR). The miniaturization of IC...

    Authors: Prashanthan Sanders, Christopher Piorkowski, Johannes A. Kragten, Grahame K. Goode, Satish R. Raj, Trang Dinh, M. Rizwan Sohail, Rishi Anand, Angel Moya-Mitjans, Noreli Franco, Kurt Stromberg and John D. Rogers

    Citation: BMC Cardiovascular Disorders 2019 19:132

    Content type: Technical advance

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  32. Gamma-glutamyltransferase (GGT) is a new predictor of cardiovascular diseases. In this study, we aimed to determine its association with ventricular arrhythmias (VAs) in implantable cardioverter-defibrillator ...

    Authors: You Zhou, Shuang Zhao, Keping Chen, Wei Hua and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:129

    Content type: Research article

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  33. Loop diuretics are recommended by clinical practice guidelines to treat volume overload in acute decompensated heart failure (ADHF). The effectiveness of switching furosemide to torsemide versus optimizing the...

    Authors: Alaa Rahhal, Mohamed Omar Saad, Kawthar Tawengi, Abed Al Raouf Assi, Masa Habra and Dalia Ahmed

    Citation: BMC Cardiovascular Disorders 2019 19:127

    Content type: Research article

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  34. Information on the role of intermittent fasting (IF) on pathologic cardiac remodeling is scarce. We compared the effects of IF before and after myocardial infarction (MI) on rat cardiac remodeling and survival.

    Authors: K. Okoshi, M. D. M. Cezar, M. A. M. Polin, J. R. Paladino Jr, P. F. Martinez, S. A. Oliveira Jr, A. R. R. Lima, R. L. Damatto, S. A. R. Paiva, L. A. M. Zornoff and M. P. Okoshi

    Citation: BMC Cardiovascular Disorders 2019 19:126

    Content type: Research article

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  35. Postoperative atrial fibrillation (POAF) is a common complication in patients with obstructive hypertrophic cardiomyopathy (HOCM) who undergo surgical myectomy. POAF is associated with poor outcome. The role o...

    Authors: Changpeng Song, Shengwei Wang, Ying Guo, Xinxin Zheng, Jie Lu, Xiaonan Fang, Shuiyun Wang and Xiaohong Huang

    Citation: BMC Cardiovascular Disorders 2019 19:122

    Content type: Research article

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  36. Atrial fibrillation (AF) is caused by different mechanisms but current treatment strategies do not target these mechanisms. Stratified therapy based on mechanistic drivers and biomarkers of AF have the potenti...

    Authors: Winnie Chua, Christina L. Easter, Eduard Guasch, Alice Sitch, Barbara Casadei, Harry J. G. M. Crijns, Doreen Haase, Stéphane Hatem, Stefan Kääb, Lluis Mont, Ulrich Schotten, Moritz F. Sinner, Karla Hemming, Jonathan J. Deeks, Paulus Kirchhof and Larissa Fabritz

    Citation: BMC Cardiovascular Disorders 2019 19:120

    Content type: Study protocol

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  37. In recent years, studies have indicated that vitamin D [25(OH)D3] and other calcium-phosphate (Ca-P) metabolism parameters and their disturbances might be potential new factors that may influence health-related q...

    Authors: Olga Mozenska, Jacek Bil, Agnieszka Segiet and Dariusz A. Kosior

    Citation: BMC Cardiovascular Disorders 2019 19:116

    Content type: Research article

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  38. Peripartum cardiomyopathy (PPCM) is a rare but potentially life-threatening complication of pregnancy. There is limited data regarding the predictors of persistent left ventricular (LV) systolic dysfunction. R...

    Authors: Firdevs Aysenur Ekizler and Serkan Cay

    Citation: BMC Cardiovascular Disorders 2019 19:114

    Content type: Research article

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  39. Impaired renal function increases the bleeding risk, leading to a conservative prescription and frequent discontinuation of oral anticoagulation in atrial fibrillation patients with chronic kidney disease (CKD...

    Authors: Blerim Luani, Conrad Genz, Joerg Herold, Andreas Mitrasch, Julius Mitusch, Marcus Wiemer, Alexander Schmeißer, Rüdiger C. Braun-Dullaeus and Thomas Rauwolf

    Citation: BMC Cardiovascular Disorders 2019 19:112

    Content type: Research article

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  40. The function of deiodinases – selenoproteins converting thyroid hormones may be disturbed by oxidative stress accompanying heart failure. Selenium (Se) may be used by glutathione peroxidase, leading to a lack ...

    Authors: Magdalena Fraczek-Jucha, Katarzyna Zbierska-Rubinkiewicz, Małgorzata Kabat, Krzysztof Plens, Radoslaw Rychlak, Jadwiga Nessler and Andrzej Gackowski

    Citation: BMC Cardiovascular Disorders 2019 19:105

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:133

  41. Arrhythmic sudden cardiac death (SCD) represents a major worldwide public health problem accounting for 15–20% of deaths. Risk stratification to identify patients at risk of SCD is crucial in order to implemen...

    Authors: C. Balla, F. Vitali, A. Brieda, F. Gualandi, A. Ferlini, M. Bertini and R. Ferrari

    Citation: BMC Cardiovascular Disorders 2019 19:104

    Content type: Review

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  42. Pulmonary embolism (PE) is a fatal condition, with a subsequent variety of complications. Although rare, the ensuing presentation of atrial fibrillation (AF) secondary to PE is evident in the literature. Howev...

    Authors: Mohammad A. Abdulsalam, Mohammed N. Elganainy and Ahmad J. Abdulsalam

    Citation: BMC Cardiovascular Disorders 2019 19:101

    Content type: Case report

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  43. Persistent left superior vena cava (PLSVC) is a rare congenital vascular anomaly. Permanent pacemaker implantation (PPI) in patients with PLSVC can be challenging because of the venous anomalies. We reported a...

    Authors: Teng Li, Qiong Xu, Hong-tao Liao, Dimitrios Asvestas, Konstantinos P. Letsas and Yifu Li

    Citation: BMC Cardiovascular Disorders 2019 19:100

    Content type: Research article

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  44. Heart failure (HF) is a common clinical syndrome, particularly in older people, and symptoms can develop gradually. The aim of this study was to explore the role of informal carers in the HF diagnostic process.

    Authors: Frances Bell-Davies, Clare Goyder, Nicola Gale, F. D. Richard Hobbs and Clare J. Taylor

    Citation: BMC Cardiovascular Disorders 2019 19:92

    Content type: Research article

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  45. The ECG characteristics of the distal coronary venous system ventricular arrhythmias (VAs) share common features with VAs arising from the aortic cusps or the endocardial left ventricular outflow tract (LVOT) ...

    Authors: Teng Li, Qiong Xu, Xian-zhang Zhan, Yu-mei Xue, Hong-tao Liao, Yi-fu Li, Konstantinos P. Letsas and Shu-lin Wu

    Citation: BMC Cardiovascular Disorders 2019 19:90

    Content type: Research article

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  46. In atrial fibrillation (AF), there are known sex and sociodemographic disparities in clinical outcomes such as stroke. We investigate whether disparities also exist with respect to patient-reported outcomes. W...

    Authors: Kelly T. Gleason, Cheryl R. Dennison Himmelfarb, Daniel E. Ford, Harold Lehmann, Laura Samuel, Hae Ra Han, Sandeep K. Jain, Gerald V. Naccarelli, Vikas Aggarwal and Saman Nazarian

    Citation: BMC Cardiovascular Disorders 2019 19:85

    Content type: Research article

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  47. Subclinical thyroid dysfunction whose typical patterns include subclinical hypothyroidism and subclinical hyperthyroidism, has been indicated to be associated with an increased risk of heart failure (HF). Howe...

    Authors: Guodong Yang, Ya Wang, Aiqun Ma and Tingzhong Wang

    Citation: BMC Cardiovascular Disorders 2019 19:83

    Content type: Research article

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