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Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    Structural remodeling is critical to the initiation and maintenance of atrial fibrillation (AF). IGF1, insulin like growth factor 1, has been recognized as contributor to fibrosis. However, the roles and mecha...

    Authors: Jiangrong Wang, Zhan Li, Juanjuan Du, Jianhua Li, Yong Zhang, Jing Liu and Yinglong Hou

    Citation: BMC Cardiovascular Disorders 2019 19:40

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  2. Content type: Research article

    Atrial fibrillation (AF) patients are routinely prescribed medications to prevent and treat complications, including those from common co-occurring comorbidities. However, adherence to such medications may be ...

    Authors: Stephanie R. Reading, Mary Helen Black, Daniel E. Singer, Alan S. Go, Margaret C. Fang, Natalia Udaltsova, Teresa N. Harrison, Rong X. Wei, In-Lu Amy Liu and Kristi Reynolds

    Citation: BMC Cardiovascular Disorders 2019 19:38

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  3. Content type: Research article

    Interatrial block (IAB) is an ECG indicator of atrial fibrosis related to atrial remodeling and thrombus formation thus leading to embolic stroke and increasing mortality. We aimed to assess weather IAB predic...

    Authors: M. A. Baturova, A. Lindgren, Y. V. Shubik, J. Carlson and P. G. Platonov

    Citation: BMC Cardiovascular Disorders 2019 19:37

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  4. Content type: Research article

    Previous randomized controlled trials (RCT)s showed similar outcomes in patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) treated with anti-arrhythmic drugs (AAD) ...

    Authors: Ahmed AlTurki, Riccardo Proietti, Ahmed Dawas, Hasan Alturki, Thao Huynh and Vidal Essebag

    Citation: BMC Cardiovascular Disorders 2019 19:18

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  5. Content type: Research article

    Peripheral artery disease (PAD) is often asymptomatic but increases the risk of developing cardiovascular events. Due to the uncertainties regarding the quality of related guidelines and a lack of clear-cut ev...

    Authors: Qinchang Chen, Lingling Li, Qingui Chen, Xixia Lin, Yonghui Li, Kai Huang and Chen Yao

    Citation: BMC Cardiovascular Disorders 2019 19:17

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  6. Content type: Research article

    LV systolic dysfunction presents an elevated risk of thromboembolism. Previous studies demonstrated low left ventricular ejection fraction (LVEF), ischemic cardiomyopathy and increased myocardial scarring as i...

    Authors: Yodying Kaolawanich and Thananya Boonyasirinant

    Citation: BMC Cardiovascular Disorders 2019 19:15

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  7. Content type: Research article

    High-dose steroids and intravenous immunoglobulin (IVIG) are controversial treatments for pediatric patients with acute myocarditis. This study aimed to investigate their efficacies in the Taiwanese pediatric ...

    Authors: Ming-Shyan Lin, Yu-Hsiang Tseng, Mei-Yen Chen, Chang-Min Chung, Ming-Horng Tsai, Po-Chang Wang, Jung-Jung Chang, Tien-Hsing Chen and Yu-Sheng Lin

    Citation: BMC Cardiovascular Disorders 2019 19:10

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  8. Content type: Case report

    Takotsubo cardiomyopathy (TCM) is a brief ventricular dysfunction that usually occurs after emotional or physical stress. Here, we report a patient who underwent cardiac surgery and then developed TCM during t...

    Authors: Jia-Hui Zeng, Wei Li, Feng-Juan Yao, Dong-Hong Liu, Cui-Ling Li, Yan-Qiu Liu, Rui Fan, Min Ye and Hong Lin

    Citation: BMC Cardiovascular Disorders 2019 19:9

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  9. Content type: Review

    Advances in the medical and surgical management of Tetralogy of Fallot have led to marked increase of the number and age of survivors. Imaging in patients with Tetralogy of Fallot plays a crucial role in the d...

    Authors: Sotiria C. Apostolopoulou, Athanassios Manginas, Nikolaos L. Kelekis and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2019 19:7

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  10. Content type: Research article

    There are limited data about modes of death and major adverse cardiovascular events (MACEs) in patients with hypertrophic cardiomyopathy (HCM) in South East Asian population. The aim of the study was to examin...

    Authors: Nattakorn Songsirisuk, Veraprapas Kittipibul, Nilubon Methachittiphan, Vorawan Charoenattasil, Nath Zungsontiporn, Ittikorn Spanuchart, Saranya Buppajarntham, Charoen Mankongpaisarnrung, Sudarat Satitthummanid, Suphot Srimahachota, Pairoj Chattranukulchai, Smonporn Boonyaratavej Songmuang and Sarinya Puwanant

    Citation: BMC Cardiovascular Disorders 2019 19:1

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  11. Content type: Research article

    Noninvasive diagnosis of allograft rejection in heart transplant recipients is challenging. The utility of 2-dimensional speckle-tracking echocardiography (2D-STE) to predict severe rejection in heart transpla...

    Authors: Andrew S. Tseng, Umama S. Gorsi, Sergio Barros-Gomes, Fletcher A. Miller, Patricia A. Pellikka, Alfredo L. Clavell and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2018 18:241

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  12. Content type: Case report

    Behcet’s disease (BD) is a systemic vasculitis characterized by oral and genital aphthosis, and ocular and skin lesions. The disease is involved in vascular, gastrointestinal, and central nervous systems. Vasc...

    Authors: Fang Jiang, Hui Xiang and Zhi-Yong Peng

    Citation: BMC Cardiovascular Disorders 2018 18:238

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  13. Content type: Debate

    Transcatheter aortic valve implantation (TAVI) has become an established therapeutic option for patients with symptomatic, severe aortic valve stenosis. Ageing of the Western and Asian population and expansion...

    Authors: Manik Chopra, Ngai H. V. Luk, Ole De Backer and Lars Søndergaard

    Citation: BMC Cardiovascular Disorders 2018 18:231

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  14. Content type: Research article

    The literature suggests that comorbid depression, defined in this paper as a history of depression prior to a cardiovascular event, has an impact on later onset depression as well as constituting increased ris...

    Authors: Serdar Sever, Su Golder and Patrick Doherty

    Citation: BMC Cardiovascular Disorders 2018 18:230

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  15. Content type: Case report

    Takotsubo syndrome (TTS) is an acute cardiac condition with reversible heart failure which is often triggered by psychological and physical stressful events. Although pulmonary embolism (PE) was reported as a ...

    Authors: Qi Jin, Qin Luo, Zhihui Zhao, Qing Zhao, Xue Yu, Lu Yan, Liu Gao and Zhihong Liu

    Citation: BMC Cardiovascular Disorders 2018 18:229

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  16. Content type: Research article

    Cardiac arrhythmias (CA) are very common and may occur with or without heart disease. Causes of these disturbances can be components of the metabolic syndrome (MetS) or deficits of micronutrients especially ma...

    Authors: Elke Parsi, Norman Bitterlich, Anne Winkelmann, Daniela Rösler and Christine Metzner

    Citation: BMC Cardiovascular Disorders 2018 18:220

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  17. Content type: Case report

    The crista terminalis is a variation of normal anatomical structure within the right atrium which may be misdiagnosed with an abnormal atrial mass normally visualized in the standard views on the transthoracic...

    Authors: Jiang Wang, Gang Wang, Xiao Bi, Ran Zhang and Changfu Liu

    Citation: BMC Cardiovascular Disorders 2018 18:210

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  18. Content type: Research article

    Atrial fibrillation (AF) is the most common complication in hypertrophic cardiomyopathy (HCM). The mechanisms of AF is associated with left atrial (LA) structural remodeling in HCM patients. However, the impac...

    Authors: Hongwei Tian, Jingang Cui, Chengzhi Yang, Fenghuan Hu, Jiansong Yuan, Shengwen Liu, Weixian Yang, Xiaowei Jiang and Shubin Qiao

    Citation: BMC Cardiovascular Disorders 2018 18:207

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  19. Content type: Research article

    Iron deficiency (ID) in patients with chronic heart failure (CHF) is considered an adverse prognostic factor. We aimed to evaluate if ID in patients with CHF is associated with increased mortality and hospital...

    Authors: José González-Costello, Josep Comín-Colet, Josep Lupón, Cristina Enjuanes, Marta de Antonio, Lara Fuentes, Pedro Moliner-Borja, Nuria Farré, Elisabet Zamora, Nicolás Manito, Ramón Pujol and Antoni Bayés-Genis

    Citation: BMC Cardiovascular Disorders 2018 18:206

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  20. Content type: Correspondence

    Standard pharmacological therapy in Takotsubo syndrome (TTS) is still debated and there is a lack of prospective data. In their recent work in BMC Cardiovascular Disorders Abanador-Kamper et al. found that str...

    Authors: Francesco Santoro, Thomas Stiermaier, Francesca Guastafierro, Nicola Tarantino, Ingo Eitel and Natale Daniele Brunetti

    Citation: BMC Cardiovascular Disorders 2018 18:205

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  21. Content type: Research article

    In diabetes, dysregulated substrate utilization and energy metabolism of myocardium can lead to heart failure. To examine the dynamic changes of myocardium, most of the previous studies conducted dynamic myoca...

    Authors: Lijun Hu, Chun Qiu, Xiaosong Wang, Mei Xu, Xiaoliang Shao and Yuetao Wang

    Citation: BMC Cardiovascular Disorders 2018 18:203

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  22. Content type: Research article

    Matrix metalloproteinase-9 (MMP9) has been reported to play a key role in the pathogenesis of aortic aneurysm. However, few studies have assessed serum MMP9 levels in both abdominal aortic aneurysm (AAA) and t...

    Authors: Tan Li, Bo Jiang, Xuan Li, Hai-yang Sun, Xin-tong Li, Jing-jing Jing and Jun Yang

    Citation: BMC Cardiovascular Disorders 2018 18:202

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  23. Content type: Case report

    Radiofrequency ablation is a common and minimally invasive procedure used to treat liver tumors. However, the potential threat of heat injury to adjacent structures if the hepatic lesion is near the diaphragm ...

    Authors: Jung-Chi Hsu, Han-Lin Tsai, Yu-Ling Lin and Rei-Yeuh Chang

    Citation: BMC Cardiovascular Disorders 2018 18:200

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  24. Content type: Review

    Long noncoding RNAs (lncRNAs) are endogenous RNA transcripts longer than 200 nucleotides which regulate epigenetically the expression of genes but do not have protein-coding potential. They are emerging as pot...

    Authors: Tarun Pant, Anuradha Dhanasekaran, Juan Fang, Xiaowen Bai, Zeljko J. Bosnjak, Mingyu Liang and Zhi-Dong Ge

    Citation: BMC Cardiovascular Disorders 2018 18:197

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  25. Content type: Case report

    Infective endocarditis due to Escherichia coli is a rare disease but is increasing in frequency, especially among older women. In addition, its mortality rate is higher than that of endocarditis due to the HACEK-...

    Authors: Nobuhiro Akuzawa and Masahiko Kurabayashi

    Citation: BMC Cardiovascular Disorders 2018 18:195

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  26. Content type: Study protocol

    Heart failure (HF) is a highly prevalent chronic disease, for which there is no cure available. Therefore, improving disease management is crucial, with mobile health (mHealth) being a promising technology. Th...

    Authors: Anneleen Baert, Els Clays, Larissa Bolliger, Delphine De Smedt, Mitja Lustrek, Aljoša Vodopija, Marko Bohanec, Paolo Emilio Puddu, Maria Costanza Ciancarelli, Michele Schiariti, Jan Derboven, Gennaro Tartarisco and Sofie Pardaens

    Citation: BMC Cardiovascular Disorders 2018 18:186

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  27. Content type: Research article

    Atrial fibrillation (AF) may result in procedure cancellations and emergency department (ED) referrals for patients presenting for outpatient GI endoscopic procedures. Such cancellations and referrals delay pa...

    Authors: Joseph Longino, Ashish Chaddha, Matthew M. Kalscheur, Anne M. Rikkers, Deepak V. Gopal, Michael E. Field and Jennifer M. Wright

    Citation: BMC Cardiovascular Disorders 2018 18:179

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  28. Content type: Research article

    Anticoagulation therapy is a standard treatment for stroke prevention in patients with non-valvular atrial fibrillation (NVAF) that have risk factors for stroke. However, anticoagulant increases the risk of bl...

    Authors: Rungroj Krittayaphong, Arjbordin Winijkul, Komsing Methavigul, Wattana Wongtheptien, Chaiyasith Wongvipaporn, Treechada Wisaratapong, Rapeephon Kunjara-Na-Ayudhya, Smonporn Boonyaratvej, Chulalak Komoltri, Pontawee Kaewcomdee, Ahthit Yindeengam and Piyamitr Sritara

    Citation: BMC Cardiovascular Disorders 2018 18:174

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  29. Content type: Case report

    Transplant renal artery stenosis (TRAS) is a serious complication after renal transplantation, leading to hypertension, deterioration in renal function, and/or graft loss. The incidence of TRAS reportedly vari...

    Authors: Yoshito Kadoya, Kan Zen and Satoaki Matoba

    Citation: BMC Cardiovascular Disorders 2018 18:172

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  30. Content type: Research article

    The interventional left atrial appendage closure (LAAC) is a guideline-conform alternative to oral anticoagulation (OAC) in non-valvular atrial fibrillation patients with OAC ineligibility. It was aimed to dir...

    Authors: Christian Fastner, Lea Hoffmann, Mohamed Aboukoura, Michael Behnes, Siegfried Lang, Martin Borggrefe, Ibrahim Akin and Christoph A. Nienaber

    Citation: BMC Cardiovascular Disorders 2018 18:171

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  31. Content type: Research article

    Pulmonary vein isolation (PVI), a cornerstone for catheter ablation of atrial fibrillation (AF), remains a complex and time-consuming procedure. Present study introduces a novel, circular-irrigated, deca-chann...

    Authors: Xiang-Fei Feng, Mu Chen, Jian Sun, Jie Sun, Bo Liang, Yi-Yong Sun and Yi-Gang Li

    Citation: BMC Cardiovascular Disorders 2018 18:168

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  32. Content type: Research article

    There is a little evidence for the effects of catheter ablation (CA) on hard endpoints in patients with atrial fibrillation (AF) and heart failure (HF).

    Authors: Yingxu Ma, Fan Bai, Fen Qin, Yixi Li, Tao Tu, Chao Sun, Shenghua Zhou and Qiming Liu

    Citation: BMC Cardiovascular Disorders 2018 18:165

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  33. Content type: Research article

    This study aimed to evaluate cost-utility of baroreflex activation therapy (BAT) using the Barostim neo™ device (CVRx Inc., Minneapolis, MN, USA) compared with optimized medical management in patients with advanc...

    Authors: Oleg Borisenko, Jochen Müller-Ehmsen, JoAnn Lindenfeld, Erik Rafflenbeul and Christian Hamm

    Citation: BMC Cardiovascular Disorders 2018 18:163

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  34. Content type: Case report

    Recent clinical trials have shown that pulmonary artery pressure-guided therapy via the CardioMEMS™ system reduces the risk of recurrent hospitalizations in chronic heart failure (HF) patients. The CardioMEMS™...

    Authors: Carsten Tschöpe, Alessio Alogna, Frank Spillmann, Alessandro Faragli, Gunther Schmidt, Florian Blaschke, Uwe Kühl, Ewa Hertel, Monika Willner, Daniel Morris, Heiner Post, Michel Noutsias, Burkert Pieske and Florian Krackhardt

    Citation: BMC Cardiovascular Disorders 2018 18:155

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  35. Content type: Research article

    Left atrial appendage morphology has been proved to be an important predictor of left atrial thrombus (LAT) and left atrial spontaneous echo contrast (LASEC) and stroke in patients with non-valvular atrial fib...

    Authors: Fan Wang, Mengyun Zhu, Xiaoyu Wang, Wei Zhang, Yang Su, Yuyan Lu, Xin Pan, Di Gao, Xianling Zhang, Wei Chen, Yawei Xu, Yuxi Sun and Dachun Xu

    Citation: BMC Cardiovascular Disorders 2018 18:153

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  36. Content type: Case report

    Lipomatous hypertrophy of the atrial septum (LHAS) is an anomaly of the heart. It is characterized by an infiltration of adipocytes into myocytes of the interatrial septum, sparing the fossa ovalis, which give...

    Authors: Grzegorz Bielicki, Marceli Lukaszewski, Kinga Kosiorowska, Jacek Jakubaszko, Rafal Nowicki and Marek Jasinski

    Citation: BMC Cardiovascular Disorders 2018 18:152

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  37. Content type: Case report

    In patients with Noonan syndrome (NS), cardiac disorders such as pulmonary valve stenosis (PS) or hypertrophic cardiomyopathy (HCM) are common. While some patients can develop heart failure associated with HCM...

    Authors: Yoshito Kadoya, Tsuneaki Kenzaka, Yohei Oda and Satoaki Matoba

    Citation: BMC Cardiovascular Disorders 2018 18:148

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  38. Content type: Research article

    It has been suggested that changes in pulmonary veins (PV) and left atrium (LA) anatomy may have an influence on initiating atrial fibrillation (AF) and the effectiveness of pulmonary vein isolation (PVI) in p...

    Authors: M. Skowerski, I. Wozniak-Skowerska, A. Hoffmann, S. Nowak, T. Skowerski, M. Sosnowski, A. M. Wnuk-Wojnar and K. Mizia-Stec

    Citation: BMC Cardiovascular Disorders 2018 18:146

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  39. Content type: Research article

    Extent of myocardial fibrosis (MF) determined using late gadolinium enhanced (LGE) predicts outcomes, but gadolinium is contraindicated in advanced renal disease. We assessed the ability of native T1-mapping t...

    Authors: M. P. Graham-Brown, A. S. Singh, G. S. Gulsin, E. Levelt, J. A. Arnold, D. J. Stensel, J. O. Burton and G. P. McCann

    Citation: BMC Cardiovascular Disorders 2018 18:145

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  40. Content type: Case report

    Intracardiac invasion of head and neck cancer is extremely rare. Here, we report a case of recurred oral cavity cancer presenting with complete atrioventricular (AV) block caused by cardiac metastasis.

    Authors: Jae Yeong Cho, Kye Hun Kim, Hyukjin Park, Hyun Ju Yoon and Jong Chun Park

    Citation: BMC Cardiovascular Disorders 2018 18:142

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  41. Content type: Case report

    Viral myocarditis presents with various symptoms, including fatal arrhythmia and cardiogenic shock, and may develop into chronic myocarditis and dilated cardiomyopathy in some patients. We report a case of vir...

    Authors: Tetsuya Yamamoto, Tsuneaki Kenzaka, Masanori Matsumoto, Ryo Nishio, Satoru Kawasaki and Hozuka Akita

    Citation: BMC Cardiovascular Disorders 2018 18:134

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  42. Content type: Research article

    In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferio...

    Authors: Claudius Hansen, Christian Loges, Karlheinz Seidl, Frank Eberhardt, Herbert Tröster, Krum Petrov, Gerian Grönefeld, Peter Bramlage, Frank Birkenhauer and Christian Weiss

    Citation: BMC Cardiovascular Disorders 2018 18:131

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  43. Content type: Research article

    Heart failure (HF) with preserved ejection fraction (HFpEF) comprises nearly half of prevalent HF, yet is challenging to curate in a large database of electronic medical records (EMR) since it requires both ac...

    Authors: Yash R. Patel, Jeremy M. Robbins, Katherine E. Kurgansky, Tasnim Imran, Ariela R. Orkaby, Robert R. McLean, Yuk-Lam Ho, Kelly Cho, J. Michael Gaziano, Luc Djousse, David R. Gagnon and Jacob Joseph

    Citation: BMC Cardiovascular Disorders 2018 18:128

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  44. Content type: Study protocol

    A previous retrospective cohort study established the relationship between perioperative atrial fibrillation (POAF) and subsequent mortality and stroke. However, the details regarding the cause of death and et...

    Authors: Satoshi Higuchi, Yusuke Kabeya, Kenichi Matsushita, Keisei Tachibana, Riken Kawachi, Hidefumi Takei, Yutaka Suzuki, Nobutsugu Abe, Yorihisa Imanishi, Kiyoshi Moriyama, Tomoko Yorozu, Koichiro Saito, Masanori Sugiyama, Haruhiko Kondo and Hideaki Yoshino

    Citation: BMC Cardiovascular Disorders 2018 18:127

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  45. Content type: Research article

    Coarctation of aorta (CoA) may progressively develop aortic dilation at other site of the aorta and can lead to fatal aortic diseases. We aimed to evaluate the occurrence of aortic dilation and related predict...

    Authors: Qin Zhao, Ke Shi, Zhi-gang Yang, Kai-yue Diao, Hua-yan Xu, Xi Liu and Ying-kun Guo

    Citation: BMC Cardiovascular Disorders 2018 18:124

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  46. Content type: Research article

    The aim of this study was to describe maternal and fetal outcomes after pregnancy complicated by peripartum cardiomyopathy (PPCM).

    Authors: Nobila Valentin Yaméogo, André Koudnoaga Samadoulougou, Larissa Justine Kagambèga, Koudougou Jonas Kologo, Georges Rosario Christian Millogo, Anna Thiam, Charles Guenancia and Patrice Zansonré

    Citation: BMC Cardiovascular Disorders 2018 18:119

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  47. Content type: Research article

    Previous studies have reported slightly higher stroke rates in Takotsubo Syndrome compared to acute myocardial infarction. Our goal was to evaluate the temporal course of stroke rates and left ventricular reco...

    Authors: Nadine Abanador-Kamper, Lars Kamper, Judith Wolfertz, Marc Vorpahl, Patrick Haage and Melchior Seyfarth

    Citation: BMC Cardiovascular Disorders 2018 18:117

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