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Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 10

  1. Catheter ablation (CA) has emerged as an effective treatment for symptomatic atrial fibrillation (AF). However practice patterns and patient factors associated with referral for CA within the first 12 months a...

    Authors: Robert N. D’Angelo, Rahul Khanna, Robert W. Yeh, Laura Goldstein, Iftekhar Kalsekar, Stephen Marcello, Patricia Tung and Peter J. Zimetbaum

    Citation: BMC Cardiovascular Disorders 2020 20:161

    Content type: Research article

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  2. We studied the course of plasma concentrations of 4 cardiovascular biomarkers: natriuretic peptides (BNP, NT-proBNP; mid-regional (MR) pro-atrial NP); and soluble endothelial CD146 (sCD146), in patients with s...

    Authors: Marc Badoz, Mattia Arrigo, Anne-Claire Mogenet, Malha Sadoune, Nicolas Meneveau, Alexandre Mebazaa and Marie-France Seronde

    Citation: BMC Cardiovascular Disorders 2020 20:157

    Content type: Research article

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  3. Danon disease (OMIM 300257) is an X-linked lysosomal storage disorder, characterized by hypertrophic cardiomyopathy (HCM), skeletal myopathy, variable intellectual disability, and other minor clinical features.

    Authors: Valeria Novelli, Antonio Bisignani, Gemma Pelargonio, Guido Primiano, Maria Lucia Narducci, Vincenzo Palmieri, Francesco Danilo Tiziano, Paolo Zeppilli, Serenella Servidei, Filippo Crea and Maurizio Genuardi

    Citation: BMC Cardiovascular Disorders 2020 20:156

    Content type: Case report

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  4. This study aimed to determine whether a focused 2-day cardiac ultrasound training course could enable physicians to obtain and interpret focused cardiac ultrasound (FCU) images from critically ill patients.

    Authors: Hongmin Zhang, Wei He, Hui Lian, Xiukai Chen, Xiaoting Wang, Yangong Chao and Dawei Liu

    Citation: BMC Cardiovascular Disorders 2020 20:151

    Content type: Research article

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  5. The incidence of CHD is the highest among birth defects and is increasing year to year. CHD seriously harms the health of infants and young children and presents a large economic burden to families and society...

    Authors: Lin Na, Bai Q, Zhao Xiumei, Zhuang Lingzi, He Deqin, Zhuang Xuanxuan, Guo Huanhuan, Lin Yuan and Chen Xiujuan

    Citation: BMC Cardiovascular Disorders 2020 20:139

    Content type: Research article

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  6. Hypoplastic left heart syndrome (HLHS) is a rare but devastating congenital heart defect (CHD) accounting for 25% of all infant deaths due to a CHD. The etiology of HLHS remains elusive, but there is increasin...

    Authors: Andrew Cheng, Whitney Neufeld-Kaiser, Peter H. Byers and Yajuan J. Liu

    Citation: BMC Cardiovascular Disorders 2020 20:137

    Content type: Case report

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  7. The subcutaneous implantable cardioverter defibrillator (S-ICD) is an alternative to the transvenous implantable cardioverter defibrillator for the prevention of sudden cardiac death. Here, we report a rare ca...

    Authors: Yasuhisa Nakao, Kazuyoshi Suenari, Kohei Yamashiro, Hiroshi Nakagawa and Nobuo Shiode

    Citation: BMC Cardiovascular Disorders 2020 20:134

    Content type: Case report

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  8. Left ventricular reverse remodeling (LVRR) has been detected in non-ischemic dilated cardiomyopathy (NIDCM) patients following optimal treatment. However, its prediction with only conventional modalities is of...

    Authors: Togo Iwahana, Sho Okada, Masato Kanda, Motohiko Oshima, Atsushi Iwama, Goro Matsumiya and Yoshio Kobayashi

    Citation: BMC Cardiovascular Disorders 2020 20:116

    Content type: Research article

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  9. Patients with coronary chronic total occlusion (CTO) require effective antiplatelet therapy after percutaneous coronary intervention (PCI). Ticagrelor has more pronounced platelet inhibition than clopidogrel. ...

    Authors: Yong Wang, Hong-wei Zhao, Cheng-fu Wang, Xiao-jiao Zhang, Jie Tao, Chun-sheng Cui, Qing-kun Meng, Yu Zhu, De-feng Luo, Ai-jie Hou and Bo Luan

    Citation: BMC Cardiovascular Disorders 2020 20:109

    Content type: Research article

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  10. In a real-world setting, the effect of pulse rate measured at the time of diagnosis and serially during follow-up and management, on outcomes in heart failure with reduced ejection fraction (HFrEF), has not be...

    Authors: Katherine E. Kurgansky, Petra Schubert, Rachel Parker, Luc Djousse, Jerome B. Riebman, David R. Gagnon and Jacob Joseph

    Citation: BMC Cardiovascular Disorders 2020 20:92

    Content type: Research article

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  11. Gigantic left atrium is defined in the current literature as an excessive dilatation of the left atrium above 65mm. Chronic mitral valve disease is associated with the development of thrombus in the left atriu...

    Authors: Lucia Masarova, Jan Novak, Martin Pesl, Jiri Ondrasek, Jiri Semenka, Eva Simarova and Roman Panovsky

    Citation: BMC Cardiovascular Disorders 2020 20:86

    Content type: Case report

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  12. Sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly which has potential for spontaneous rupture into other cardiac chambers or the pericardial space (depending on its location). A ruptured SVA has a ver...

    Authors: Ata Doost, Julie-Ann Craig and Siang Yong Soh

    Citation: BMC Cardiovascular Disorders 2020 20:84

    Content type: Case report

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  13. Tanshinone IIA (TS IIA), a multi-pharmaceutical compound from traditional Chinese herb, is effective for treatment of atherothrombosis. However, the underlying mechanisms of TS IIA-mediated anti-platelet activ...

    Authors: Hua Wang, Lin Zhong, Shaohua Mi, Nianpeng Song, Wei Zhang and Ming Zhong

    Citation: BMC Cardiovascular Disorders 2020 20:81

    Content type: Research article

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  14. Contrast-induced encephalopathy (CIE) is a rare complication of cardiac catheterization; clinical manifestations include cortical blindness, seizures and focal neurological deficits. In general, recurrent epil...

    Authors: Pingping Lei, Weiping He, Quan Shi, Meiying Sun and Zhigang Sun

    Citation: BMC Cardiovascular Disorders 2020 20:79

    Content type: Case report

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  15. Percutaneous closure (LAAC) of the left atrial appendage (LAA) is an efficacious preventive procedure for patients with non-valvular atrial fibrillation (NVAF) and considerable bleeding risk. We sought to syst...

    Authors: Muhammad Ali, Angelos G. Rigopoulos, Mammad Mammadov, Abdelrahman Torky, Andrea Auer, Marios Matiakis, Elena Abate, Constantinos Bakogiannis, Stergios Tzikas, Boris Bigalke, Daniel Sedding and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2020 20:78

    Content type: Review

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  16. Arrhythmogenic cardiomyopathy (AC) is one of the leading causes for sudden cardiac death (SCD). Recent studies have identified mutations in cardiac desmosomes as key players in the pathogenesis of AC. However,...

    Authors: Xiaoping Lin, Yuankun Ma, Zhejun Cai, Qiyuan Wang, Lihua Wang, Zhaoxia Huo, Dan Hu, Jian’an Wang and Meixiang Xiang

    Citation: BMC Cardiovascular Disorders 2020 20:74

    Content type: Research article

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  17. Cardiac tamponade is a rare but serious complication of Takotsubo cardiomyopathy (TC). Two cases of cardiac tamponade subsequent to TC have been reported. The pericardial effusion in these cases was hemorrhagi...

    Authors: Yuta Nagamori, Takuto Hamaoka, Hisayoshi Murai, Shinichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Hiroshi Furusho, Masaaki Kawashiri and Masayuki Takamura

    Citation: BMC Cardiovascular Disorders 2020 20:67

    Content type: Case report

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  18. Autophagy plays a crucial role in the pathological process of cardiovascular diseases. However, little is known about the pathological mechanism underlying autophagy regulation in dilated cardiomyopathy (DCM).

    Authors: Bo Jin, Haiming Shi, Jun Zhu, Bangwei Wu and Quzhen Geshang

    Citation: BMC Cardiovascular Disorders 2020 20:56

    Content type: Research article

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  19. The optimal duration of oral anticoagulant therapy for patients with venous thromboembolism (VTE) remains highly uncertain in clinical practice. It is essential to accurately assess the effect of anticoagulant...

    Authors: Wei Wang, Yang Su, Chunyan Wu, Yuxi Sun, Neng Dai, Wei Chen, Jie Zhang, Yawei Xu, Ralph G. Brindis, Dachun Xu and Jue Li

    Citation: BMC Cardiovascular Disorders 2020 20:53

    Content type: Research article

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  20. The etiology of Takayasu arteritis (TA) is unknown; however, a possible relationship between streptococcal infection and TA has been proposed. This study aimed to identify the clinical features and cardiac val...

    Authors: Lili Pan, Juan Du, Junming Zhu, Zhiyu Qiao, Yanlong Ren, Xinsheng Huang, Shichao Guo and Na Gao

    Citation: BMC Cardiovascular Disorders 2020 20:52

    Content type: Research article

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  21. Aortic valve regurgitation (AR) results in left ventricle (LV) volume overload (VO) leading to its dilation and hypertrophy (H). We study a rat model of severe AR induced by puncturing one or two leaflets usin...

    Authors: Elisabeth Walsh-Wilkinson, Marie-Claude Drolet, Marie Arsenault and Jacques Couet

    Citation: BMC Cardiovascular Disorders 2020 20:51

    Content type: Research article

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  22. Previous studies demonstrated impaired lipid metabolism and augmented aerobic glycolysis in AF. The authors aimed to investigate whether the use of metformin, an AMPK activator, could reverse this metabolic re...

    Authors: Yaozhong Liu, Fan Bai, Na Liu, Baojian Zhang, Fen Qin, Tao Tu, Biao Li, Jiayi Li, Yingxu Ma, Feifan Ouyang and Qiming Liu

    Citation: BMC Cardiovascular Disorders 2020 20:50

    Content type: Research article

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  23. Three-dimensional electroanatomic mapping systems have demonstrated a significant reduction in radiation exposure during radiofrequency catheter ablation procedures. We aimed to investigate the safety, feasibi...

    Authors: Guangzhi Chen, Yan Wang, Riccardo Proietti, Xunzhang Wang, Feifan Ouyang, Chang Sheng Ma, Rong Hui Yu, Chunxia Zhao, Kezhong Ma, Jie Qiu, Qigong Liu and Dao Wen Wang

    Citation: BMC Cardiovascular Disorders 2020 20:48

    Content type: Research article

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  24. Cardiac surgery for prosthetic valve endocarditis (PVE) is associated with substantial mortality. We aimed to analyze 30-day and 1-year outcome in patients undergoing surgery for PVE and sought to identify pre...

    Authors: Carolyn Weber, Parwis B. Rahmanian, Melanie Nitsche, Asmae Gassa, Kaveh Eghbalzadeh, Stefanie Hamacher, Julia Merkle, Antje-Christin Deppe, Anton Sabashnikov, Elmar W. Kuhn, Oliver J. Liakopoulos and Thorsten Wahlers

    Citation: BMC Cardiovascular Disorders 2020 20:47

    Content type: Research article

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  25. The current diagnostic methods and treatments still fail to lower the incidence of anthracycline-induced cardiotoxicity effectively. In this study, we aimed to (1) analyze the cardiotoxicity-related genes afte...

    Authors: Wang Yadi, Chen Shurui, Zhang Tong, Chen Suxian, Tong Qing and He Dongning

    Citation: BMC Cardiovascular Disorders 2020 20:43

    Content type: Research article

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  26. We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF) taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and bleeding risk.

    Authors: Alexandros Briasoulis, Yubo Gao, Chakradhari Inampudi, Paulino Alvarez, Rabea Asleh, Elizabeth Chrischilles, Enrique C. Leira and Mary Vaughan-Sarrazin

    Citation: BMC Cardiovascular Disorders 2020 20:42

    Content type: Research article

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  27. Although mineral metabolism disorder influences cardiac valvular calcification (CVC), few previous studies have examined the effects of non-calcium-containing and calcium-containing phosphate binders on CVC in...

    Authors: Kentaro Watanabe, Hideki Fujii, Keiji Kono, Shunsuke Goto and Shinichi Nishi

    Citation: BMC Cardiovascular Disorders 2020 20:39

    Content type: Research article

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  28. Atrial fibrillation with symptomatic bradycardia, higher grade atrioventricular block, and sinus node disease are all common indications for permanent pacemaker implantation. The most frequent causes of sinus ...

    Authors: Jörg Reifart, Marlene Tschernatsch, Christian W. Hamm, Johannes Sperzel and Andreas Hain

    Citation: BMC Cardiovascular Disorders 2020 20:30

    Content type: Case report

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  29. The gut microbiome plays an important role in various cardiovascular diseases, such as atherosclerosis and hypertension, which are associated with abdominal aortic aneurysms (AAAs).

    Authors: Jiahe Xie, Weiling Lu, Lintao Zhong, Yuhua Hu, Qingrui Li, Rongming Ding, Zhonggao Zhong, Ziyou Liu, Hai Xiao, Dongming Xie, Guofu Zheng, Bo Ye, Yiming Zhong and Zuheng Liu

    Citation: BMC Cardiovascular Disorders 2020 20:32

    Content type: Research article

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  30. Evidence-based recommendations about anticoagulation in acute type B aortic dissection (TBAD) are completely missing, but there is a diffuse conviction that it could prevent the healing process of the dissecte...

    Authors: Pier Paolo Bocchino, Ovidio De Filippo, Francesco Piroli, Paolo Scacciatella, Massimo Imazio, Fabrizio D’Ascenzo and Gaetano Maria De Ferrari

    Citation: BMC Cardiovascular Disorders 2020 20:29

    Content type: Case report

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  31. TAB2 is an activator of MAP 3 K7/TAK1, which is required for the IL-1 induced signal pathway. Microdeletions encompassing TAB2 have been detected in various patients with congenital heart defects (CHD), indicatin...

    Authors: Jia Chen, Huizhen Yuan, Kang Xie, Xinrong Wang, Linglong Tan, Yongyi Zou, Yan Yang, Lu Pan, Junfang Xiao, Ge Chen and Yanqiu Liu

    Citation: BMC Cardiovascular Disorders 2020 20:27

    Content type: Case report

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  32. Sarcoidosis is a systemic granulomatous disease that may affect the myocardium. This study evaluated the diagnostic and prognostic value of 2-dimensional speckle tracking echocardiography in cardiac sarcoidosi...

    Authors: Cristina Di Stefano, Giulia Bruno, Maria C. Arciniegas Calle, Gayatri A. Acharya, Lynn M. Fussner, Patompong Ungprasert, Leslie T. Cooper Jr, Lori A. Blauwet, Jay H. Ryu, Patricia A. Pellikka, Eva M. Carmona Porquera and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2020 20:21

    Content type: Research article

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  33. Acute heart failure is a rapid onset of new or worsening of signs and symptoms of heart failure that requires hospitalization or a visit to the emergency department. The aim of this study was to evaluate treat...

    Authors: Mulubirhan Tirfe, Teshome Nedi, Desalew Mekonnen and Alemseged Beyene Berha

    Citation: BMC Cardiovascular Disorders 2020 20:16

    Content type: Research article

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  34. Both acute myocardial infarction and acute pulmonary embolism are distinct medical urgencies while they may conincide. Leriche’s syndrome is a relatively rare aortoiliac occlusive disease characterized by clau...

    Authors: Xuanqi An, Rui Fu, Zhihui Zhao, Xinhai Ni, Changming Xiong, Xiansheng Cheng and Zhihong Liu

    Citation: BMC Cardiovascular Disorders 2020 20:26

    Content type: Case report

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  35. Cardiorenal syndrome (CRS) is a group of pathophysiological disorders affecting heart and kidneys.

    Authors: E. Hryniewiecka, T. Hryniewiecki, J. Różański, T. Pilecki, R. Zagożdżon, T. Orłowski, M. Gołębiowski, L. Pączek, K. Mucha and B. Foroncewicz

    Citation: BMC Cardiovascular Disorders 2020 20:20

    Content type: Case report

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  36. It has been reported that oral anticoagulation (OAC) is underused among Chinese patients with non-valvular atrial fibrillation (NVAF). Non-vitamin K antagonist oral anticoagulants (NOAC) have been recommended ...

    Authors: Ting Liu, Hui-li Yang, Lan Gu, Jie Hui, Ojo Omorogieva, Meng-xiao Ren and Xiao-hua Wang

    Citation: BMC Cardiovascular Disorders 2020 20:22

    Content type: Research article

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  37. End-stage renal disease (ESRD) patients are at high cardiovascular risk, and myocardial fibrosis (MF) accounts for most of their cardiac events. The purpose of this study is to investigate the prognostic value...

    Authors: Hua-yan Xu, Zhi-gang Yang, Yi Zhang, Wan-lin Peng, Chun-chao Xia, Zhen-lin Li, Yong He, Rong Xu, Li Rao, Ying Peng, Yu-ming Li, Hong-ling Gao and Ying-kun Guo

    Citation: BMC Cardiovascular Disorders 2020 20:12

    Content type: Research article

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  38. Preclinical studies indicate iron deficiency (ID) plays an important role in cardiac remodelling. However, the relationship between ID and cardiac remodelling remains unknown in clinical setting. This retrospe...

    Authors: Yan Chen, Jing Wan, Haidan Xia, Ya Li, Yufeng Xu, Haiyan Lin and Hassah Iftikhar

    Citation: BMC Cardiovascular Disorders 2020 20:4

    Content type: Research article

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  39. Chymase is the major angiotensin II (Ang II)-forming enzyme in cardiovascular tissue, with an important role in atrial remodeling. This study aimed to examine the association between chymase 1 gene (CMA1) polymor...

    Authors: Dongchen Zhou, Yuewei Chen, Jiaxin Wu, Jiabo Shen, Yushan Shang, Liangrong Zheng and Xudong Xie

    Citation: BMC Cardiovascular Disorders 2019 19:321

    Content type: Research article

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  40. Non-cardiac surgery for hypertrophic obstructive cardiomyopathy (HOCM) is considered to require meticulous perioperative care. β-blockers are considered the first-line drugs for patients with HOCM, and they pl...

    Authors: Yoichi Imori, Hitoshi Takano, Hiroshi Mase, Junya Matsuda, Hideto Sangen, Yuki Izumi, Yukichi Tokita, Takeshi Yamamoto and Wataru Shimizu

    Citation: BMC Cardiovascular Disorders 2019 19:316

    Content type: Research article

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  41. Transesophageal echocardiography may be used to assess pulmonary veins for atrial fibrillation ablation. No study focused on the role of transthoracic echocardiography (TTE) in evaluating the diameter and anat...

    Authors: Qing-Qing Dong, Wen-Yi Yang, Ya-Ping Sun, Qian Zhang, Guang Chu, Gen-Qing Zhou, Gang Chen, Song-Wen Chen, Shao-Wen Liu and Fang Wang

    Citation: BMC Cardiovascular Disorders 2019 19:315

    Content type: Research article

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  42. Whipple’s disease is a clinically relevant multi-system disorder that is often undiagnosed given its elusive nature. We present an atypical case of Whipple’s disease involving pan-valvular endocarditis and con...

    Authors: Christina S. Thornton, Yinong Wang, Martin Köebel, Kathryn Bernard, Tamara Burdz, Andrew Maitland, Jose G. Ferraz, Paul L. Beck and Andre Ferland

    Citation: BMC Cardiovascular Disorders 2019 19:312

    Content type: Case report

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  43. The most significant manifestation of heart failure is exercise intolerance. This systematic review and meta-analysis was performed to investigate whether dipeptidyl peptidase-4 (DPP-4) inhibitors or glucagon-lik...

    Authors: Chengcong Chen, Ying Huang, Yongmei Zeng, Xiyan Lu and Guoqing Dong

    Citation: BMC Cardiovascular Disorders 2019 19:311

    Content type: Research article

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  44. The optimal level of heart rate (HR) control in patients with atrial fibrillation (AF) is unknown. To assess the effect of rate control on cardiopulmonary exercise capacity and quality of life (QoL) in permane...

    Authors: Fei She, Yuan Ma, Yi Li, Lei Li, Weixian Xu, Hongyan Wang and Ming Cui

    Citation: BMC Cardiovascular Disorders 2019 19:308

    Content type: Research article

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  45. Calcific aortic valve disease (CAVD) is an atheroinflammatory process; finally it leads to progressive calcification of the valve. There is no effective pharmacological treatment for CAVD and many of the under...

    Authors: Jonna Weisell, Pauli Ohukainen, Juha Näpänkangas, Steffen Ohlmeier, Ulrich Bergmann, Tuomas Peltonen, Panu Taskinen, Heikki Ruskoaho and Jaana Rysä

    Citation: BMC Cardiovascular Disorders 2019 19:306

    Content type: Research article

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  46. Endomyocardial fibrosis (EMF) represents the most common cause of restrictive cardiomyopathy worldwide. Despite a high prevalence in tropical regions, it occasionally occurs in patients who have never visited ...

    Authors: Gernot Wagner, Markus Haumer, Gerhard Poelzl, Dominik Wiedemann, Andreas Kliegel, Robert Ullrich, Gerald Gartlehner, Andreas Zuckermann, Ludwig Müller, Harald Mayr and Deddo Moertl

    Citation: BMC Cardiovascular Disorders 2019 19:302

    Content type: Case report

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  47. Patients with some mutations in the lamin A/C (LMNA) gene are characterized by the presence of dilated cardiomyopathy (DCM), conduction abnormalities, ventricular tachyarrhythmias (VT), and sudden cardiac death (...

    Authors: Tetsuro Yokokawa, Shohei Ichimura, Naoko Hijioka, Takashi Kaneshiro, Akiomi Yoshihisa, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Osamu Suzuki, Seiko Ohno, Takeshi Aiba, Hiroshi Ohtani and Yasuchika Takeishi

    Citation: BMC Cardiovascular Disorders 2019 19:298

    Content type: Case report

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