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Non-coronary artery cardiac disease

Section edited by Michel Noutsias

This section concerns all aspects of non-coronary artery cardiac disease including but not limited to: arrhythmias, congenital cardiac disease and cardiomyopathies. The section considers articles concerning the prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

Page 1 of 9

  1. Evidence-based recommendations about anticoagulation in acute type B aortic dissection (TBAD) are completely missing, but there is a diffuse conviction that it could prevent the healing process of the dissecte...

    Authors: Pier Paolo Bocchino, Ovidio De Filippo, Francesco Piroli, Paolo Scacciatella, Massimo Imazio, Fabrizio D’Ascenzo and Gaetano Maria De Ferrari

    Citation: BMC Cardiovascular Disorders 2020 20:29

    Content type: Case report

    Published on:

  2. TAB2 is an activator of MAP 3 K7/TAK1, which is required for the IL-1 induced signal pathway. Microdeletions encompassing TAB2 have been detected in various patients with congenital heart defects (CHD), indicatin...

    Authors: Jia Chen, Huizhen Yuan, Kang Xie, Xinrong Wang, Linglong Tan, Yongyi Zou, Yan Yang, Lu Pan, Junfang Xiao, Ge Chen and Yanqiu Liu

    Citation: BMC Cardiovascular Disorders 2020 20:27

    Content type: Case report

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  3. Sarcoidosis is a systemic granulomatous disease that may affect the myocardium. This study evaluated the diagnostic and prognostic value of 2-dimensional speckle tracking echocardiography in cardiac sarcoidosi...

    Authors: Cristina Di Stefano, Giulia Bruno, Maria C. Arciniegas Calle, Gayatri A. Acharya, Lynn M. Fussner, Patompong Ungprasert, Leslie T. Cooper Jr, Lori A. Blauwet, Jay H. Ryu, Patricia A. Pellikka, Eva M. Carmona Porquera and Hector R. Villarraga

    Citation: BMC Cardiovascular Disorders 2020 20:21

    Content type: Research article

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  4. Acute heart failure is a rapid onset of new or worsening of signs and symptoms of heart failure that requires hospitalization or a visit to the emergency department. The aim of this study was to evaluate treat...

    Authors: Mulubirhan Tirfe, Teshome Nedi, Desalew Mekonnen and Alemseged Beyene Berha

    Citation: BMC Cardiovascular Disorders 2020 20:16

    Content type: Research article

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  5. Both acute myocardial infarction and acute pulmonary embolism are distinct medical urgencies while they may conincide. Leriche’s syndrome is a relatively rare aortoiliac occlusive disease characterized by clau...

    Authors: Xuanqi An, Rui Fu, Zhihui Zhao, Xinhai Ni, Changming Xiong, Xiansheng Cheng and Zhihong Liu

    Citation: BMC Cardiovascular Disorders 2020 20:26

    Content type: Case report

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  6. Cardiorenal syndrome (CRS) is a group of pathophysiological disorders affecting heart and kidneys.

    Authors: E. Hryniewiecka, T. Hryniewiecki, J. Różański, T. Pilecki, R. Zagożdżon, T. Orłowski, M. Gołębiowski, L. Pączek, K. Mucha and B. Foroncewicz

    Citation: BMC Cardiovascular Disorders 2020 20:20

    Content type: Case report

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  7. It has been reported that oral anticoagulation (OAC) is underused among Chinese patients with non-valvular atrial fibrillation (NVAF). Non-vitamin K antagonist oral anticoagulants (NOAC) have been recommended ...

    Authors: Ting Liu, Hui-li Yang, Lan Gu, Jie Hui, Ojo Omorogieva, Meng-xiao Ren and Xiao-hua Wang

    Citation: BMC Cardiovascular Disorders 2020 20:22

    Content type: Research article

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  8. End-stage renal disease (ESRD) patients are at high cardiovascular risk, and myocardial fibrosis (MF) accounts for most of their cardiac events. The purpose of this study is to investigate the prognostic value...

    Authors: Hua-yan Xu, Zhi-gang Yang, Yi Zhang, Wan-lin Peng, Chun-chao Xia, Zhen-lin Li, Yong He, Rong Xu, Li Rao, Ying Peng, Yu-ming Li, Hong-ling Gao and Ying-kun Guo

    Citation: BMC Cardiovascular Disorders 2020 20:12

    Content type: Research article

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  9. Preclinical studies indicate iron deficiency (ID) plays an important role in cardiac remodelling. However, the relationship between ID and cardiac remodelling remains unknown in clinical setting. This retrospe...

    Authors: Yan Chen, Jing Wan, Haidan Xia, Ya Li, Yufeng Xu, Haiyan Lin and Hassah Iftikhar

    Citation: BMC Cardiovascular Disorders 2020 20:4

    Content type: Research article

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  10. Chymase is the major angiotensin II (Ang II)-forming enzyme in cardiovascular tissue, with an important role in atrial remodeling. This study aimed to examine the association between chymase 1 gene (CMA1) polymor...

    Authors: Dongchen Zhou, Yuewei Chen, Jiaxin Wu, Jiabo Shen, Yushan Shang, Liangrong Zheng and Xudong Xie

    Citation: BMC Cardiovascular Disorders 2019 19:321

    Content type: Research article

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  11. Non-cardiac surgery for hypertrophic obstructive cardiomyopathy (HOCM) is considered to require meticulous perioperative care. β-blockers are considered the first-line drugs for patients with HOCM, and they pl...

    Authors: Yoichi Imori, Hitoshi Takano, Hiroshi Mase, Junya Matsuda, Hideto Sangen, Yuki Izumi, Yukichi Tokita, Takeshi Yamamoto and Wataru Shimizu

    Citation: BMC Cardiovascular Disorders 2019 19:316

    Content type: Research article

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  12. Transesophageal echocardiography may be used to assess pulmonary veins for atrial fibrillation ablation. No study focused on the role of transthoracic echocardiography (TTE) in evaluating the diameter and anat...

    Authors: Qing-Qing Dong, Wen-Yi Yang, Ya-Ping Sun, Qian Zhang, Guang Chu, Gen-Qing Zhou, Gang Chen, Song-Wen Chen, Shao-Wen Liu and Fang Wang

    Citation: BMC Cardiovascular Disorders 2019 19:315

    Content type: Research article

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  13. Whipple’s disease is a clinically relevant multi-system disorder that is often undiagnosed given its elusive nature. We present an atypical case of Whipple’s disease involving pan-valvular endocarditis and con...

    Authors: Christina S. Thornton, Yinong Wang, Martin Köebel, Kathryn Bernard, Tamara Burdz, Andrew Maitland, Jose G. Ferraz, Paul L. Beck and Andre Ferland

    Citation: BMC Cardiovascular Disorders 2019 19:312

    Content type: Case report

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  14. The most significant manifestation of heart failure is exercise intolerance. This systematic review and meta-analysis was performed to investigate whether dipeptidyl peptidase-4 (DPP-4) inhibitors or glucagon-lik...

    Authors: Chengcong Chen, Ying Huang, Yongmei Zeng, Xiyan Lu and Guoqing Dong

    Citation: BMC Cardiovascular Disorders 2019 19:311

    Content type: Research article

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  15. The optimal level of heart rate (HR) control in patients with atrial fibrillation (AF) is unknown. To assess the effect of rate control on cardiopulmonary exercise capacity and quality of life (QoL) in permane...

    Authors: Fei She, Yuan Ma, Yi Li, Lei Li, Weixian Xu, Hongyan Wang and Ming Cui

    Citation: BMC Cardiovascular Disorders 2019 19:308

    Content type: Research article

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  16. Calcific aortic valve disease (CAVD) is an atheroinflammatory process; finally it leads to progressive calcification of the valve. There is no effective pharmacological treatment for CAVD and many of the under...

    Authors: Jonna Weisell, Pauli Ohukainen, Juha Näpänkangas, Steffen Ohlmeier, Ulrich Bergmann, Tuomas Peltonen, Panu Taskinen, Heikki Ruskoaho and Jaana Rysä

    Citation: BMC Cardiovascular Disorders 2019 19:306

    Content type: Research article

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  17. Endomyocardial fibrosis (EMF) represents the most common cause of restrictive cardiomyopathy worldwide. Despite a high prevalence in tropical regions, it occasionally occurs in patients who have never visited ...

    Authors: Gernot Wagner, Markus Haumer, Gerhard Poelzl, Dominik Wiedemann, Andreas Kliegel, Robert Ullrich, Gerald Gartlehner, Andreas Zuckermann, Ludwig Müller, Harald Mayr and Deddo Moertl

    Citation: BMC Cardiovascular Disorders 2019 19:302

    Content type: Case report

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  18. The optimal dosage for cryoablation of atrial fibrillation (Cryo-AF) is still unknown. To evaluate the efficacy of an individualized freeze duration, we compared the clinical outcome of patients treated with a...

    Authors: Jun Ding, Jing Xu, Wei Ma, Bingwei Chen, Peigen Yang, Yu Qi, Shan Sun and Aijuan Cheng

    Citation: BMC Cardiovascular Disorders 2019 19:299

    Content type: Research article

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  19. Patients with some mutations in the lamin A/C (LMNA) gene are characterized by the presence of dilated cardiomyopathy (DCM), conduction abnormalities, ventricular tachyarrhythmias (VT), and sudden cardiac death (...

    Authors: Tetsuro Yokokawa, Shohei Ichimura, Naoko Hijioka, Takashi Kaneshiro, Akiomi Yoshihisa, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Osamu Suzuki, Seiko Ohno, Takeshi Aiba, Hiroshi Ohtani and Yasuchika Takeishi

    Citation: BMC Cardiovascular Disorders 2019 19:298

    Content type: Case report

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  20. Late gadolinium enhancement (LGE) using cardiac magnetic resonance (CMR) characterizes myocardial disease and predicts an adverse cardiovascular (CV) prognosis. Myocardial abnormalities, are present in early c...

    Authors: Anna M. Price, Manvir K. Hayer, Ravi Vijapurapu, Saad A. Fyyaz, William E. Moody, Charles J. Ferro, Jonathan N. Townend, Richard P. Steeds and Nicola C. Edwards

    Citation: BMC Cardiovascular Disorders 2019 19:295

    Content type: Research article

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  21. Patients after aortic coarctation (CoA) repair show impaired aortic bioelasticity and altered left ventricular (LV) mechanics, predisposing diastolic dysfunction. Our purpose was to assess aortic bioelasticity...

    Authors: Theresa Pieper, Heiner Latus, Dietmar Schranz, Joachim Kreuder, Bettina Reich, Kerstin Gummel, Helge Hudel and Inga Voges

    Citation: BMC Cardiovascular Disorders 2019 19:286

    Content type: Research article

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  22. Advanced echocardiography techniques such as speckle tracking imaging are sensitive diagnostic tools frequently used in various clinical and scientific scenarios. Importantly, imperfect reproducibility and dep...

    Authors: Kai O. Hensel

    Citation: BMC Cardiovascular Disorders 2019 19:281

    Content type: Commentary

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  23. Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and glycemic control affect the pathogenesis of AF has not ...

    Authors: Qing Wang, Jing Wang, Pei Wang, Liaoyuan Wang, Lanting Jia, Xinyu Ling, Wang Xi, Jie Min, Hua Shen, Jian Xiao, Jinxiang Yuan and Zhinong Wang

    Citation: BMC Cardiovascular Disorders 2019 19:278

    Content type: Research article

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  24. Evidences regarding the associations between maternal upper respiratory tract infection/influenza during pregnancy and the risk of congenital heart disease (CHD) is still controversial. This study was specific...

    Authors: Y. Q. Xia, K. N. Zhao, A. D. Zhao, J. Z. Zhu, H. F. Hong, Y. L. Wang and S. H. Li

    Citation: BMC Cardiovascular Disorders 2019 19:277

    Content type: Research article

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  25. Several studies have reported on atrial fibrillation (AF) outcomes, including thromboembolism in patients with paroxysmal and non-paroxysmal AF; however the findings still remain controversial on whether risks...

    Authors: Ying Wang, Chang-Sheng Ma, Xin Du, Liu He, Jie Li, Guo-Hong Wang, Dan Wen, Jian-Zeng Dong, Jian-Hong Pan and Gregory Y. H. Lip

    Citation: BMC Cardiovascular Disorders 2019 19:283

    Content type: Research article

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  26. Left ventricular global longitudinal strain (GLS) with cardiovascular magnetic resonance (CMR) is an important prognostic biomarker. Its everyday clinical use is limited due to methodological and postprocessin...

    Authors: Robert Heinke, Faraz Pathan, Melanie Le, Tommaso D’Angelo, Lea Winau, Christophe Arendt, Thomas J. Vogl, Andreas Zeiher, Eike Nagel and Valentina O. Puntmann

    Citation: BMC Cardiovascular Disorders 2019 19:267

    Content type: Research article

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  27. High risk of embolic events exists in both patients with chronic atrial fibrillation (AF) and patients in the perioperative period of ablation (effective treatment for AF). Therefore, anticoagulant therapy is ...

    Authors: Jian Yang, Xuan Zhang, Xi-ying Wang, Chi Zhang, Song-zan Chen and Shen-Jiang Hu

    Citation: BMC Cardiovascular Disorders 2019 19:261

    Content type: Research article

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  28. Depression is associated with increased mortality and poor prognosis in patients with cardiovascular disease (CVD). However, little is known about the patient characteristics associated with new onset post hea...

    Authors: Serdar Sever, Patrick Doherty, Alexander Stephen Harrison and Su Golder

    Citation: BMC Cardiovascular Disorders 2019 19:256

    Content type: Research article

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  29. The PhysioHeart™ is a mature acute platform, based isolated slaughterhouse hearts and able to validate cardiac devices and techniques in working mode. Despite perfusion, myocardial edema and time-dependent fun...

    Authors: Benjamin Kappler, Carlos A. Ledezma, Sjoerd van Tuijl, Veronique Meijborg, Bastiaan J. Boukens, Bülent Ergin, P. J. Tan, Marco Stijnen, Can Ince, Vanessa Díaz-Zuccarini and Bas A. J. M. de Mol

    Citation: BMC Cardiovascular Disorders 2019 19:254

    Content type: Research article

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  30. Pulmonary embolism (PE) is associated to high mortality rate worldwide. However, the diagnosis of PE often results inaccurate. Many cases of PE are incorrectly diagnosed or missed and they are often associated...

    Authors: Gelsomina Mansueto, Dario Costa, Emanuele Capasso, Federica Varavallo, Giuseppina Brunitto, Rosanna Caserta, Salvatore Esposito, Massimo Niola, Celestino Sardu, Raffaele Marfella, Claudio Napoli and Mariano Paternoster

    Citation: BMC Cardiovascular Disorders 2019 19:250

    Content type: Research article

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  31. Conventional pharmacologic therapies aim to reduce fluid overload in advanced heart failure (HF) represented by intravenous (IV) loop diuretics (LDs) have sometimes not so efficacious and been reported to have...

    Authors: Ying Yang, Chao Shen, Jiangting Lu, Fen Xu, Jinshan Tong, Jiangfen Jiang and Guosheng Fu

    Citation: BMC Cardiovascular Disorders 2019 19:249

    Content type: Study protocol

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  32. The leading cause of mortality of thalassemia major patients is iron overload cardiomyopathy. Early diagnosis with searching for left ventricular diastolic dysfunction before the systolic dysfunction ensued mi...

    Authors: Benjaporn Chinprateep, Nithima Ratanasit, Yodying Kaolawanich, Khemajira Karaketklang, Pairash Saiviroonporn, Vip Viprakasit and Rungroj Krittayaphong

    Citation: BMC Cardiovascular Disorders 2019 19:245

    Content type: Research article

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  33. Care coordination between general practitioners (GPs) and cardiovascular specialists is expected to play a key role in establishing appropriate oral anticoagulant (OAC) treatment in atrial fibrillation (AF) pa...

    Authors: Fumiko Ono, Sayako Akiyama, Akifumi Suzuki, Yoshinobu Ikeda, Akira Takahashi, Hitoshi Matsuoka, Masahiro Sasaki, Tomonori Okamura and Nariaki Yoshihara

    Citation: BMC Cardiovascular Disorders 2019 19:235

    Content type: Research article

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  34. Ventricular arrhythmias (VAs) arising from the origin above pulmonary valve lack comprehensive investigation. This study aimed to disclose the characteristics and radiofrequency catheter ablation (RFCA) outcom...

    Authors: Jin Li, Cheng Zheng, Zhi-Rui Liu, Jun Ma, Ge Jin, Wei-Qian Lin, Yao-Yao Wang and Jia-Feng Lin

    Citation: BMC Cardiovascular Disorders 2019 19:233

    Content type: Research article

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  35. Because of previous ventricular arrhythmia (VA) episodes, patients with implantable cardioverter-defibrillator (ICD) for secondary prevention (SP) are generally considered to have a higher burden of VAs than p...

    Authors: You Zhou, Shuang Zhao, Keping Chen, Wei Hua, Yangang Su, Silin Chen, Zhaoguang Liang, Wei Xu and Shu Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:230

    Content type: Research article

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  36. Transcatheter closure of perimembranous ventricular septal defects is one of the greatest challenges in interventional cardiology. Short- and midium-term follow-up data for large samples are limited. This repo...

    Authors: Hao Li, Youyang Shi, Songyue Zhang, Yue Ren, Xing Rong, Zhenquan Wang, Tianhe Xia, Tingting Wu, Haitang Xu, Yaoyao Yan, Yi Zhan, Maoping Chu and Rongzhou Wu

    Citation: BMC Cardiovascular Disorders 2019 19:222

    Content type: Research article

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  37. Patients with reduced ejection fraction have high rates of mortality and readmission after hospitalization for heart failure. In Taiwan, heart failure disease management programs (HFDMPs) have proven effective...

    Authors: Shyh-Ming Chen, Yen-Nan Fang, Lin-Yi Wang, Ming-Kung Wu, Po-Jui Wu, Tsung-Hsun Yang, Yung-Lung Chen and Chi-Ling Hang

    Citation: BMC Cardiovascular Disorders 2019 19:220

    Content type: Research article

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  38. Cardiac fibrosis is a crucial aspect of cardiac remodeling that can severely affect cardiac function. Cardiac fibroblasts surely influence this process. Besides, macrophage plays an essential role in cardiac r...

    Authors: Yan Che, Di-Fei Shen, Zhao-Peng Wang, Ya-Ge Jin, Qing-Qing Wu, Sha-Sha Wang and Yuan Yuan

    Citation: BMC Cardiovascular Disorders 2019 19:219

    Content type: Research article

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  39. Cardiac power output (CPO), derived from the product of cardiac output and mean aortic pressure, is an important yet underexploited parameter for hemodynamic monitoring of critically ill patients in the intens...

    Authors: Dawud Abawi, Alessandro Faragli, Michael Schwarzl, Martin Manninger, David Zweiker, Karl-Patrik Kresoja, Jochen Verderber, Birgit Zirngast, Heinrich Maechler, Paul Steendijk, Burkert Pieske, Heiner Post and Alessio Alogna

    Citation: BMC Cardiovascular Disorders 2019 19:217

    Content type: Research article

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  40. There is limited information regarding left atrial (LA) mechanics in aortic valve stenosis (AS). We assessed LA mechanics in AS through speckle-tracking echocardiography (STE) according to severity and prognosis.

    Authors: Patrícia Marques-Alves, Ana Vera Marinho, Rogério Teixeira, Rui Baptista, Graça Castro, Rui Martins and Lino Gonçalves

    Citation: BMC Cardiovascular Disorders 2019 19:215

    Content type: Research article

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  41. Heart failure (HF) with mid-range ejection fraction (EF) (HFmrEF) has attracted increasing attention in recent years. However, the understanding of HFmrEF remains limited, especially among Asian patients. Ther...

    Authors: Siqi Lyu, Litian Yu, Huiqiong Tan, Shaoshuai Liu, Xiaoning Liu, Xiao Guo and Jun Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:209

    Content type: Research article

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  42. Colchicine has been used as anti-inflammatory agent in pericardial effusion (PE). We sought to perform a meta-analysis of randomized trials assessing the efficacy and safety of colchicine in patients with peri...

    Authors: Leon L. Lutschinger, Angelos G. Rigopoulos, Peter Schlattmann, Marios Matiakis, Daniel Sedding, Paul Christian Schulze and Michel Noutsias

    Citation: BMC Cardiovascular Disorders 2019 19:207

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:227

  43. Cellular therapies have been increasingly applied to diverse human diseases. Intracoronary infusion of bone marrow-derived mononuclear cells (BMMNC) has demonstrated to improve ventricular function after acute...

    Authors: Miguel Romero, José Suárez-de-Lezo, Concha Herrera, Manuel Pan, José López-Aguilera, José Suárez-de-Lezo Jr, Flor Baeza-Garzón, Francisco Javier Hidalgo-Lesmes, Olga Fernández-López, Juliana Martínez-Atienza, Eva Cebrián, Vanesa Martín-Palanco, Rosario Jiménez-Moreno, Rosario Gutiérrez-Fernández, Sonia Nogueras, Maria Dolores Carmona…

    Citation: BMC Cardiovascular Disorders 2019 19:203

    Content type: Study protocol

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  44. Pregnancy-associated Venous thromboembolism (VTE) is one of the most common causes of maternal morbidity and mortality in developed countries. In this study, we aimed to systematically review and critical appr...

    Authors: Jie Zheng, Qinchang Chen, Jing Fu, Yanling Lu, Tianjun Han and Ping He

    Citation: BMC Cardiovascular Disorders 2019 19:199

    Content type: Research article

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  45. Cardiac pacing is a growing activity in Sub-Saharan Africa. There is little data on the characteristics of this interventional treatment in our regions. The goal was to evaluate the results of cardiac pacing i...

    Authors: Adama Kane, Simon Antoine Sarr, Juliette Valerie Danièle Ndobo, Alioune Tabane, Kana Babaka, Fatou Aw, Malick Bodian, Serigne Mor Beye, Momar Dioum, Aliou Alassane Ngaidé, Mouhamadou Bamba Ndiaye, Alassane Mbaye, Maboury Diao, Abdoul Kane and Serigne Abdou BA

    Citation: BMC Cardiovascular Disorders 2019 19:197

    Content type: Research article

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  46. Left atrial appendage closure is increasingly used. LAA closure procedures can rarely be complicated by device embolization, typically towards the aorta. In this case report, we describe the successful percuta...

    Authors: Manik Chopra, Yam-Hong Wong, Lars Søndergaard and Ole De Backer

    Citation: BMC Cardiovascular Disorders 2019 19:196

    Content type: Case report

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  47. In patients with cardiac resynchronization therapy (CRT), atrial fibrillation (AF) is associated with an unfavorable outcome and may cause loss of biventricular pacing (BivP). An effective delivery of BivP of ...

    Authors: Jonatan Jacobsson, Christian Reitan, Jonas Carlson, Rasmus Borgquist and Pyotr G. Platonov

    Citation: BMC Cardiovascular Disorders 2019 19:195

    Content type: Research article

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  48. Mineralocorticoid receptor antagonists (MRA) are an underutilized therapy for heart failure with a reduced ejection fraction (HFrEF), but the current impact of hospitalization on MRA use is not well characteri...

    Authors: Matthew S. Durstenfeld, Stuart D. Katz, Hannah Park and Saul Blecker

    Citation: BMC Cardiovascular Disorders 2019 19:194

    Content type: Research article

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  49. Swallow or deglutition syncope is an unusual type of neurally-mediated syncope associated with life-threatening bradyarrhythmia and hypotension. It is a difficult condition to diagnose with commonly delayed di...

    Authors: Kelvin Shenq Woei Siew, Maw Pin Tan, Ida Normiha Hilmi and Alexander Loch

    Citation: BMC Cardiovascular Disorders 2019 19:191

    Content type: Case report

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  50. The development of novel oral anticoagulants (NOACs) has changed the landscape of non-valvular atrial fibrillation (NVAF) management. In this study, the effectiveness and the safety of several NOACs were evalu...

    Authors: Jianchao Zhang, Junnan Tang, Xiaolin Cui, Bo Wang, Mengsen Bu, Yan Bai, Kai Wang, Jiacheng Guo, Deliang Shen and Jinying Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:182

    Content type: Research article

    Published on: