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Hypertension and cardiovascular risk

This section concerns all aspects of hypertension and peripheral vascular disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology. This section also considers articles concerning patients at high cardiovascular risk, including but not limited to patients with metabolic syndrome and diabetes.

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  1. Cardiovascular secondary preventive recommendations are often not reached. We investigated whether a nurse-led telephone-based follow-up could improve the implementation of a new guideline within a year after ...

    Authors: Stina Jakobsson, Daniel Huber, Fredrik Björklund and Thomas Mooe

    Citation: BMC Cardiovascular Disorders 2016 16:77

    Content type: Research article

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  2. The aim of this study was to examine recommended target levels of low-density lipoprotein cholesterol (LDL-C) for hyperlipidaemia patients at high risk (i.e., with two or more risk factors or coronary heart di...

    Authors: S. Mitchell, S. Roso, M. Samuel and M. Pladevall-Vila

    Citation: BMC Cardiovascular Disorders 2016 16:74

    Content type: Research article

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  3. Adverse effects, treatment resistance and high costs associated with pharmacological treatment of hypertension have led to growing interest in non-pharmacological complementary therapies such as music interven...

    Authors: Anne Y. R. Kühlmann, Jonathan R. G. Etnel, Jolien W. Roos-Hesselink, Johannes Jeekel, Ad J. J. C. Bogers and Johanna J. M. Takkenberg

    Citation: BMC Cardiovascular Disorders 2016 16:69

    Content type: Research article

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  4. Peripheral arterial disease (PAD) is a major health problem in diabetes patients in high-income countries, but the PAD burden in sub-Saharan Africa is largely undetermined. We studied the prevalence of PAD and...

    Authors: Kwame Yeboah, Peter Puplampu, Joana Ainuson, Josephine Akpalu, Ben Gyan and Albert G. B. Amoah

    Citation: BMC Cardiovascular Disorders 2016 16:68

    Content type: Research article

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  5. Essential hypertension has been extensively reported to cause endothelial dysfunction. The aim of this study was to evaluate the effects of barnidipine or lercanidipine, in addition to losartan, on some parame...

    Authors: Giuseppe Derosa, Amedeo Mugellini, Rosa Maria Pesce, Angela D’Angelo and Pamela Maffioli

    Citation: BMC Cardiovascular Disorders 2016 16:66

    Content type: Research article

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  6. Within-class comparative effectiveness studies of β-blockers have not been performed in the chronic dialysis setting. With widespread cardiac disease in these patients and potential mechanistic differences wit...

    Authors: Theresa I. Shireman, Jonathan D. Mahnken, Milind A. Phadnis and Edward F. Ellerbeck

    Citation: BMC Cardiovascular Disorders 2016 16:60

    Content type: Research article

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  7. Pulse wave velocity is an important measure of cardiovascular risk, and can be measured by several different techniques. We compared age-related changes in pulse wave velocity derived from carotid and femoral ...

    Authors: Jehill D. Parikh, Kieren G. Hollingsworth, Vijay Kunadian, Andrew Blamire and Guy A. MacGowan

    Citation: BMC Cardiovascular Disorders 2016 16:50

    Content type: Research article

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  8. The CD4+ T-lymphocytes and their subtype CD4 + CD25highFoxP3+ regulatory T cells are receiving growing interest as major regulators of atherogenesis. We sought to investigate 1) whether the CD4 + cell subsets wer...

    Authors: Luigina Guasti, Andrea Maria Maresca, Laura Schembri, Emanuela Rasini, Francesco Dentali, Alessandro Squizzato, Catherine Klersy, Laura Robustelli Test, Christian Mongiardi, Leonardo Campiotti, Walter Ageno, Anna Maria Grandi, Marco Cosentino and Franca Marino

    Citation: BMC Cardiovascular Disorders 2016 16:26

    Content type: Research article

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  9. The aim of the present study was to evaluate changes in microvascular density and reactivity in patients with type 1 diabetes (T1D) resulting from low intensity chronic exercise training.

    Authors: Roger de Moraes, Diogo Van Bavel, Marília de Brito Gomes and Eduardo Tibiriçá

    Citation: BMC Cardiovascular Disorders 2016 16:23

    Content type: Research article

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  10. Hypertension is an increasing problem in Southeast Asia, particularly in Bangladesh. Although some epidemiological studies on hypertension have been conducted in Bangladesh, the factors associated with hyperte...

    Authors: Muhammad Abdul Baker Chowdhury, Md. Jamal Uddin, Md. Rabiul Haque and Boubakari Ibrahimou

    Citation: BMC Cardiovascular Disorders 2016 16:22

    Content type: Research article

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  11. There is still no standard large animal model for evaluating the effectiveness of potential thrombolytic therapies. Here, we aimed to develop a new beagle model with ST-elevation myocardial infarction (STEMI) ...

    Authors: Hong Zhang, Yong-chun Cui, Yi Tian, Wei-min Yuan, Jian-zhong Yang, Peng Peng, Kai Li, Xiao-peng Liu, Dong Zhang, Ai-li Wu, Zhou Zhou and Yue Tang

    Citation: BMC Cardiovascular Disorders 2016 16:21

    Content type: Research article

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  12. Hyperhomocysteinemia (HHcy) is an independent risk factor for various cardiovascular diseases. Animal studies have shown that homocysteine (Hcy) inhibits hepatic expression of apolipoprotein AI (apoAI). Our re...

    Authors: Ying Wang, Jia Liu, Yuliang Jiang, Heng Zhang, Song Leng and Guang Wang

    Citation: BMC Cardiovascular Disorders 2016 16:10

    Content type: Research article

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  13. To determine whether the professional Omron HBP-1300 blood pressure (BP) monitor meets American Association for the Advancement of Medical Instrumentation (AAMI) accuracy standards in Chinese children and adults.

    Authors: Linghui Meng, Di Zhao, Yan Pan, Wenqing Ding, Qing Wei, Hua Li, Pingjin Gao and Jie Mi

    Citation: BMC Cardiovascular Disorders 2016 16:9

    Content type: Research article

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  14. African Americans (AAs) have lower lung function, higher blood pressure variability (BPV) and increased risk for hypertension and cardiovascular disease (CVD) compared with whites. The mechanism through which ...

    Authors: John N. Booth III, Nicole Redmond, Mario Sims, Daichi Shimbo and Paul Muntner

    Citation: BMC Cardiovascular Disorders 2016 16:6

    Content type: Research article

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  15. Blood pressure (BP) variability is associated with target organ damage in hypertension and diabetes. The 24 h ambulatory blood pressure monitoring (24 h-ABPM) has been proposed as an evaluation for BP variabil...

    Authors: Daniela Massierer, Liana Farias Leiria, Mateus Dorneles Severo, Priscila Dos Santos Ledur, Alexandre Dalpiaz Becker, Fernanda Mus Aguiar, Eliandra Lima, Valéria Centeno Freitas, Beatriz D. Schaan and Miguel Gus

    Citation: BMC Cardiovascular Disorders 2016 16:4

    Content type: Research article

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  16. Smoking is the most important reversible cardiovascular risk factor. It is well established that quitting smoking reduces coronary events. However, on several occasions, the cardiovascular safety of smoking ce...

    Authors: André Pacheco Silva, Jaqueline Scholz, Tania Ogawa Abe, Gabriela Gouveia Pinheiro, Patricia Viviane Gaya, Alexandre Costa Pereira and Paulo Caleb Junior Lima Santos

    Citation: BMC Cardiovascular Disorders 2016 16:2

    Content type: Research article

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  17. In the initiation and maintenance of arrhythmia, inflammatory processes play an important role. IL-2 is a pro-inflammatory factor which is associated with the morbidity of arrhythmias, however, how IL-2 affect...

    Authors: Yuanyuan Zhao, Qiaobing Sun, Zhipeng Zeng, Qianqian Li, Shiyuan Zhou, Mengchen Zhou, Yumei Xue, Xiang Cheng, Yunlong Xia, Qing Wang and Xin Tu

    Citation: BMC Cardiovascular Disorders 2016 16:1

    Content type: Research article

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  18. The American Heart Association developed the Life’s Simple 7 metric for defining cardiovascular health. Little is known, however, whether co-occurring reproductive factors, which affects endogenous oestrogen l...

    Authors: Xia Cao, Jiansong Zhou, Hong Yuan and Zhiheng Chen

    Citation: BMC Cardiovascular Disorders 2015 15:176

    Content type: Research article

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  19. To examine whether lower insulin sensitivity as determined by homeostatic model assessment (HOMA-%S) was associated with increased left ventricular mass (LVM) and presence of LV diastolic dysfunction at long-t...

    Authors: Mette Lundgren Nielsen, Manan Pareek, Oke Gerke, Margrét Leósdóttir, Peter M. Nilsson and Michael Hecht Olsen

    Citation: BMC Cardiovascular Disorders 2015 15:168

    Content type: Research article

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  20. Paracetamol’s solubility is achieved by adding to the excipient sodium salts, either as bicarbonate, carbonate or citrate. As the relationship between salt and hypertension is well known, due to the sodium con...

    Authors: Mencia Benitez-Camps, Ernest Vinyoles-Bargalló, Oriol Rebagliato-Nadal, Rosa Morros-Pedrós, Helena Pera-Pujadas, Antoni Dalfó-Baqué, Ignacio López-Pavón, Carlos Roca-Sánchez, Rosa Maria Coma-Carbó, Mariano De La Figuera Von Wichmann, Lucas Mengual-Martínez, Carmen Yuste-Marco, Montserrat Teixidó-Colet, Josep M. Pepió i Vilaubí, Riera Ciurana-Tost, Rosa Pou-Vila…

    Citation: BMC Cardiovascular Disorders 2015 15:167

    Content type: Study protocol

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  21. The distribution of cerebral ischemic infarction and stenosis in ischemic stroke may vary with age-group, race and gender. This study was conducted to understand the risk factors and characteristics of cerebra...

    Authors: Rajeev Ojha, Dongya Huang, Hedi An, Rong Liu, Cui Du, Nan Shen, Zhilan Tu and Ying Li

    Citation: BMC Cardiovascular Disorders 2015 15:158

    Content type: Research article

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  22. European guidelines on primary prevention of cardiovascular disease (CVD) recommend the SCORE risk charts for determining CVD risk, which include blood pressure and serum cholesterol as risk parameters. To fac...

    Authors: Niels V. van der Hoeven, Maurice A. J. Niessen, Erik S. G. Stroes, Lex Burdorf, Roderik A. Kraaijenhagen and Bert-Jan H. van den Born

    Citation: BMC Cardiovascular Disorders 2015 15:140

    Content type: Research article

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  23. Aortic pulse wave velocity (PWV) has been shown to be an independent predictor of cardiovascular mortality in patients with end-stage renal disease and the general population. Atmospheric particulate- matter (...

    Authors: Cheng-Hao Weng, Ching-Chih Hu, Tzung-Hai Yen and Wen-Hung Huang

    Citation: BMC Cardiovascular Disorders 2015 15:115

    Content type: Research article

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  24. Observational studies can provide important information on the efficacy and safety of antihypertensive agents in the real-life clinical setting. AdADOSE was a large observational study to assess the effectiven...

    Authors: Ahmed K. Motaweih, Elena Usova, Wajid Hussain, Ziad Dello, Birgit Schmidt and Thomas Petri

    Citation: BMC Cardiovascular Disorders 2015 15:35

    Content type: Research article

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  25. South Asian males constitute the largest proportion of the United Arab Emirates (UAE) population. Minimal data is available on the prevalence of hypertension among South Asian immigrants in the UAE. We determi...

    Authors: Syed M Shah, Tom Loney, Mohamud Sheek-Hussein, Mohamed El Sadig, Salma Al Dhaheri, Iffat El Barazi, Layla Al Marzouqi, Tar-Ching Aw and Raghib Ali

    Citation: BMC Cardiovascular Disorders 2015 15:30

    Content type: Research article

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  26. Waist circumference threshold values used in sub-Saharan Africa correspond to those of European populations and are therefore inappropriate. Thus, they may over predict insulin resistance, especially in hypert...

    Authors: Philippe Bianga Katchunga, Achile Mwira Bapolisi, Jean-René M’Buyamba-Kabangu and Michel P Hermans

    Citation: BMC Cardiovascular Disorders 2015 15:17

    Content type: Research article

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  27. Adiponectin is a biomarker that is associated with type 2 diabetes and hypertension. Lower circulating level is a risk factor. Higher levels are protective. African Americans have a higher prevalence of type 2...

    Authors: Sharon K Davis, Samson Y Gebreab, Ruihua Xu, Pia Riestra, Rumana J Khan, Anne E Sumner, DeMarc Hickson and Aurelian Bidulescu

    Citation: BMC Cardiovascular Disorders 2015 15:13

    Content type: Research article

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  28. The objective was to compare the improvements in lifestyle and risk factor profiles in patients with and without diabetes mellitus (DM) in the intervention arm of EUROACTION study.

    Authors: Sandra N Ofori and Kornelia Kotseva

    Citation: BMC Cardiovascular Disorders 2015 15:11

    Content type: Research article

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  29. In subjects with hypercholesterolaemia, cholesterol values remain above guideline levels. One of the limiting factors to the achievement of goals in such patients is therapeutic non-adherence. The aim of this ...

    Authors: Ignacio Párraga-Martínez, Joseba Rabanales-Sotos, Fernando Lago-Deibe, Juan M Téllez-Lapeira, Francisco Escobar-Rabadán, Alejandro Villena-Ferrer, Mariano Blasco-Valle, José M Ferreras-Amez, Susana Morena-Rayo, José M del Campo-del Campo, Maria Candelaria Ayuso-Raya and José J Pérez-Pascual

    Citation: BMC Cardiovascular Disorders 2015 15:8

    Content type: Study protocol

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  30. The role of serum 25-hydroxyvitamin D (25 (OH) D) in atherogenesis is unclear. We investigated whether the 25 (OH) D is independently associated with the carotid intima–media thickness (CIMT) and carotid plaqu...

    Authors: Hui Ma, Huandong Lin, Yu Hu, Xiaoming Li, Wanyuan He, Xuejuan Jin, Jian Gao, Naiqing Zhao, Zhenqi Liu and Xin Gao

    Citation: BMC Cardiovascular Disorders 2014 14:197

    Content type: Research article

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  31. Despite the progressive increase in life expectancy and the relationship between aging with multi-morbidities and the increased use of healthcare resources, current clinical practice guidelines (CPG) on cardio...

    Authors: Ricardo Gómez-Huelgas, Vicente Giner-Galvañ, José M Mostaza, José I Cuende, Jose M de Miguel-Yanes, Eduardo Rovira, Demetrio Sánchez-Fuentes, Carmen Suárez Fernández and Pilar Román Sánchez

    Citation: BMC Cardiovascular Disorders 2014 14:193

    Content type: Debate

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  32. Metformin, an insulin-sensitizer, may correct several physiologic abnormalities owing to insulin resistance in patients with type 2 diabetes mellitus (DM). The effects of metformin on venous thrombosis in pati...

    Authors: Dai-Yin Lu, Chin-Chou Huang, Po-Hsun Huang, Chia-Min Chung, Shing-Jong Lin, Jaw-Wen Chen, Wan-Leong Chan and Hsin-Bang Leu

    Citation: BMC Cardiovascular Disorders 2014 14:187

    Content type: Research article

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  33. Metabolic syndrome is characterized by the association of 3 or more risk factors, including: abdominal obesity associated with an excess of abdominal fat, insulin resistance, type 2 diabetes, dyslipidemia and ...

    Authors: Filipe Fernandes Conti, Janaina de Oliveira Brito, Nathalia Bernardes, Danielle da Silva Dias, Iris Callado Sanches, Christiane Malfitano, Susana Francisca Llesuy, Maria-Claudia Irigoyen and Kátia De Angelis

    Citation: BMC Cardiovascular Disorders 2014 14:185

    Content type: Research article

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  34. It is indicated that non-HDL cholesterol and lipid ratios, including total/HDL cholesterol and LDL/HDL cholesterol ratios, are risk indicators with greater predictive value for coronary atherosclerotic progres...

    Authors: Caie Yang, Zhiqiang Sun, Yunpeng Li, Junping Ai, Qiyu Sun and Yaping Tian

    Citation: BMC Cardiovascular Disorders 2014 14:181

    Content type: Research article

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  35. We sought to determine whether heart rate variability (HRV), blood pressure (BP) variability, and baroreceptor-heart rate reflex sensitivity can be reliably assessed using finger volume pulse waveforms obtaine...

    Authors: Jonathan R Linder, Harald M Stauss, Holly Gindes, Gary L Pierce, Nicholas H Von Bergen, William G Haynes and Jess G Fiedorowicz

    Citation: BMC Cardiovascular Disorders 2014 14:180

    Content type: Research article

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  36. Asymptomatic or silent pulmonary embolism (S-PE) in patients with deep vein thrombosis has been the focus of numerous publications with the objective of determining the incidence of S-PE and assessing whether ...

    Authors: Maria José García-Fuster, Maria José Fabia, Elena Furió, Gernot Pichler, Josep Redon, Maria José Forner and Fernando Martínez

    Citation: BMC Cardiovascular Disorders 2014 14:178

    Content type: Research article

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  37. Data is sparse concerning the magnitude of metabolic syndrome (MetS) in developing countries like Ethiopia whose major health problem had long been under-nutrition and infectious diseases rather than non-commu...

    Authors: Belaynesh Tachebele, Molla Abebe, Zelalem Addis and Nebiyu Mesfin

    Citation: BMC Cardiovascular Disorders 2014 14:177

    Content type: Research article

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  38. In cases where antidiabetic monotherapy is unable to sufficiently control glucose levels in patients with type-2 diabetes, treatment needs to be intensified. Determining factors that may be predictors for the ...

    Authors: Peter Bramlage, Anselm K Gitt, Steffen Schneider, Evelin Deeg and Diethelm Tschöpe

    Citation: BMC Cardiovascular Disorders 2014 14:162

    Content type: Research article

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  39. Vitamin D deficiency is associated with cardiovascular (CV) risk in multiple populations, including those with chronic kidney disease (CKD). The active form of the hormone (1,25 OH2D3) binds to receptors in multi...

    Authors: Adeera Levin, Taylor Perry, Prathibha De Zoysa, Mhairi K Sigrist, Karin Humphries, Mila Tang and Ognjenka Djurdjev

    Citation: BMC Cardiovascular Disorders 2014 14:156

    Content type: Study protocol

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  40. Obesity is associated with the onset of type 2 diabetes mellitus (T2D), but reports conflict regarding the association between obesity and macrovascular complications. In this study, we investigated associatio...

    Authors: Luis A Vázquez, Ángel Rodríguez, Javier Salvador, Juan F Ascaso, Helmut Petto and Jesús Reviriego

    Citation: BMC Cardiovascular Disorders 2014 14:153

    Content type: Research article

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  41. Previous studies indicated that the clustering of major cardiovascular disease (CVD) risk factors is common, and multiple unhealthy lifestyles are responsible for the clustering of CVD risk factors. However, l...

    Authors: Xianglei Kong, Xiaojing Ma, Jing Yao, Shuting Zheng, Meiyu Cui and Dongmei Xu

    Citation: BMC Cardiovascular Disorders 2014 14:151

    Content type: Research article

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  42. The effects of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) on cardiovascular (CV) risk in hypertensive patients with type 2 diabetes mellitus (T2 DM) are uncertai...

    Authors: Guang Hao, Zengwu Wang, Rui Guo, Zuo Chen, Xin Wang, Linfeng Zhang and Wei Li

    Citation: BMC Cardiovascular Disorders 2014 14:148

    Content type: Research article

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  43. Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocia...

    Authors: Cília Mejía-Lancheros, Ramón Estruch, Miguel-Angel Martínez-González, Jordi Salas-Salvadó, Olga Castañer, Dolores Corella, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Emilio Ros, Javier Díez-Espino, Josep Basora, José-V Sorlí…

    Citation: BMC Cardiovascular Disorders 2014 14:135

    Content type: Research article

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  44. The purpose of this study was, in high-risk patients, to simultaneously estimate the effect of metabolic syndrome (MetS) on diastolic or systolic heart failure (DHF or SHF), to evaluate MetS predictive value f...

    Authors: Zi-Hui Tang, Lin Wang, Fangfang Zeng and Keqin Zhang

    Citation: BMC Cardiovascular Disorders 2014 14:124

    Content type: Research article

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  45. Reduced β2-glycoprotein I (reduced β2GP I), which has free sulfhydryl groups, is present in plasma and serum; it can protect vascular endothelial cells from damage due to oxidative stress in vitro. We investigate...

    Authors: Jun Xu, Penghua Wang, Tong Wang, Meijun Wang, Sisi Chen, Pei Yu and Demin Yu

    Citation: BMC Cardiovascular Disorders 2014 14:114

    Content type: Research article

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  46. The presence of echolucent carotid plaques as defined by low ultrasound grey-scale median (GSM) is associated with a higher risk of stroke and myocardial infarction. Betablockers have shown possible anti-ather...

    Authors: Giuseppe Asciutto, Nuno V Dias, Ana Persson, Jan Nilsson and Isabel Gonçalves

    Citation: BMC Cardiovascular Disorders 2014 14:111

    Content type: Research article

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  47. Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims t...

    Authors: Cilia Mejia-Lancheros, Ramón Estruch, Miguel Angel Martínez-González, Jordi Salas-Salvadó, Dolores Corella, Enrique Gómez-Gracia, Miquel Fiol, José Manuel Santos, Montse Fitó, Fernando Arós, Lluis Serra-Majem, Xavier Pintó, Josep Basora, José Vicente Sorlí and Miguel-Angel Muñoz

    Citation: BMC Cardiovascular Disorders 2014 14:109

    Content type: Research article

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  48. From 2005 to 2011 Mazowe District recorded a gradual decline in prevalence of hypertension in the face of rising incidence of complications like stroke. This raised questions on whether diagnosis and managemen...

    Authors: More Mungati, Portia Manangazira, Lucia Takundwa, Notion T Gombe, Simbarashe Rusakaniko and Mufuta Tshimanga

    Citation: BMC Cardiovascular Disorders 2014 14:102

    Content type: Research article

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  49. Home (HBPM) and ambulatory (ABPM) blood pressure measurements have their advantages and disadvantages in diagnosing and managing hypertension. We studied HBPMs and ABPMs in volunteers taking part in a survey.

    Authors: Sigrun Chrubasik-Hausmann, Cosima Chrubasik, Brigitte Walz, Jürgen Schulte Mönting and Paul Erne

    Citation: BMC Cardiovascular Disorders 2014 14:94

    Content type: Research article

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  50. The optimal cutoff of the waist-to-hip ratio (WHR) among Han adults in Xinjiang, which is located in the center of Asia, is unknown. We aimed to examine the relationship between different WHRs and cardiovascul...

    Authors: Shuang-Shuang Li, Shuo Pan, Yi-Tong Ma, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Zhen-Yan Fu, Xiang Xie, Fen Liu, You Chen, Bang-Dang Chen, Zi-Xiang Yu, Chun-Hui He, Ying-Ying Zheng, Nuremanguli Abudukeremu, Jialin Abuzhalihan…

    Citation: BMC Cardiovascular Disorders 2014 14:93

    Content type: Research article

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