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Hypertension and cardiovascular risk

This section concerns all aspects of hypertension and peripheral vascular disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology. This section also considers articles concerning patients at high cardiovascular risk, including but not limited to patients with metabolic syndrome and diabetes.

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  1. Patient self-management (PSM) of vitamin K antagonists (VKA) seems a very promising model of care for oral anticoagulation in terms of efficacy and safety. In comparison with other management models of VKA the...

    Authors: M. Corrochano, B. Jiménez, J. Millón, I. Gich, M. Rambla, E. Gil, P. Caparrós, R. Macho and J. C. Souto

    Citation: BMC Cardiovascular Disorders 2020 20:166

    Content type: Research article

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  2. Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality o...

    Authors: Tora Hagsund, Sven-Erik Olsson, J. Gustav Smith, Bjarne Madsen Hardig and Henrik Wagner

    Citation: BMC Cardiovascular Disorders 2020 20:165

    Content type: Research article

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  3. Several models have been developed to predict asymptomatic carotid stenosis (ACS), however these models did not pay much attention to people with lower level of stenosis (<50% or carotid plaques, especially in...

    Authors: Junxiong Yin, Chuanyong Yu, Hongxing Liu, Mingyang Du, Feng Sun, Cheng Yu, Lixia Wei, Chongjun Wang and Xiaoshan Wang

    Citation: BMC Cardiovascular Disorders 2020 20:164

    Content type: Research article

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  4. The COngenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry is the first registry for congenital heart disease (CHD) and CHD-related pulmonary hypertension (PH) in adults in Indonesia...

    Authors: Lucia Kris Dinarti, Anggoro Budi Hartopo, Arditya Damar Kusuma, Muhammad Gahan Satwiko, Muhammad Reyhan Hadwiono, Aditya Doni Pradana and Dyah Wulan Anggrahini

    Citation: BMC Cardiovascular Disorders 2020 20:163

    Content type: Research article

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  5. Hypertensive disorders of pregnancy (HDP) is one of the leading causes of maternal and neonatal mortality, increasing the long-term incidence of cardiovascular diseases. Preeclampsia and gestational hypertensi...

    Authors: Yamin Hou, Lin Yun, Lihua Zhang, Jingru Lin and Rui Xu

    Citation: BMC Cardiovascular Disorders 2020 20:155

    Content type: Research article

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  6. Globally, cardiovascular diseases (CVDs) have continued to ravage the human existence through the premature deaths of its workforce. Despite this burden, many studies in Nigeria have focused on determining the...

    Authors: Olaniyan Akintunde Babatunde, Sunday Olakunle Olarewaju, Adeleye Abiodun Adeomi, Joel Olufunminiyi Akande, Adebobola Bashorun, Chukwuma David Umeokonkwo and James Olusegun Bamidele

    Citation: BMC Cardiovascular Disorders 2020 20:154

    Content type: Research article

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  7. We hypothesized that discriminating the early subclinical organ damage would serve as a great opportunity for prevention against atherosclerotic cardiovascular disease (ASCVD). Brachial-ankle pulse wave veloci...

    Authors: Qiaowei Li, Fan Lin, Zhonghai Gao, Feng Huang and Pengli Zhu

    Citation: BMC Cardiovascular Disorders 2020 20:145

    Content type: Research article

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  8. Ascending aortic aneurysms are one of the major causes of mortality. In recent years, there is a growing interest of epicardial adipose tissue (EAT) and related diseases. The aim of this study was to investiga...

    Authors: Onur Argan, Eyup Avci, Tarik Yildirim and Ozgen Safak

    Citation: BMC Cardiovascular Disorders 2020 20:142

    Content type: Research article

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  9. Matrix metalloproteinase-9 (MMP-9) participates in the degradation of components of the extracellular matrix and it is involved in vascular remodeling and vasomotor changes. The aim of this study was to invest...

    Authors: Flavia Mariana Valente, Days Oliveira de Andrade, Luciana Neves Cosenso-Martin, Cláudia Bernardi Cesarino, Sérgio Mussi Guimarães, Victor Beneditti Guimarães, Riccardo Lacchini, José Eduardo Tanus-Santos, Juan Carlos Yugar-Toledo and José Fernando Vilela-Martin

    Citation: BMC Cardiovascular Disorders 2020 20:132

    Content type: Research article

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  10. Hypertension is a major contributing factor to cardiovascular disease and is a leading cause of death in the world. The association between hepatic enzymes and hypertension has been reported in limited studies...

    Authors: Sadaqur Rahman, Shiful Islam, Tangigul Haque, Rahanuma Raihanu Kathak and Nurshad Ali

    Citation: BMC Cardiovascular Disorders 2020 20:128

    Content type: Research article

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  11. To date, the best adiposity index that predicts or associates strongly with hypertension remains controversial. Therefore, we aimed to compare the performance of different adiposity indices [BMI (body mass ind...

    Authors: Lihua Hu, Guiping Hu, Xiao Huang, Wei Zhou, Chunjiao You, Juxiang Li, Ping Li, Yanqing Wu, Qinghua Wu, Zengwu Wang, Runlin Gao, Huihui Bao and Xiaoshu Cheng

    Citation: BMC Cardiovascular Disorders 2020 20:115

    Content type: Research article

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  12. Whether pre-diabetes in the absence of hypertension (HTN) or dyslipidemia (DLP) is a risk factor for occurrence of major adverse cardiovascular events (MACE) is not fully established. We investigated the effec...

    Authors: Nahid Hashemi Madani, Faramarz Ismail-Beigi, Hossein Poustchi, Mahdi Nalini, Sadaf G. Sepanlou, Mojtaba Malek, Mohammad Amin Abbasi, Alireza Khajavi, Mohammad E. Khamseh and Reza Malekzadeh

    Citation: BMC Cardiovascular Disorders 2020 20:113

    Content type: Research article

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  13. Point-of-care haemoglobin meters are attractive solutions to improve timely diagnosis of anaemia in resource-limited settings. However, concerns regarding the accuracy of these meters may affect their adoption...

    Authors: Simeon-Pierre Choukem, Colette Sih, Akondu Tontu Ntumsi, Christian Akem Dimala, Yannick Mboue-Djieka, Eveline D. T. Ngouadjeu and Andre-Pascal Kengne

    Citation: BMC Cardiovascular Disorders 2020 20:111

    Content type: Research article

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  14. Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subject...

    Authors: Sadegh Jafarnejad, Hamed Mirzaei, Cain C. T. Clark, Mohsen Taghizadeh and Armin Ebrahimzadeh

    Citation: BMC Cardiovascular Disorders 2020 20:98

    Content type: Research article

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  15. Major adverse cardiovascular events are the main cause of morbidity and mortality over the long term in patients undergoing carotid endarterectomy. There are few reports assessing the prognostic value of marke...

    Authors: David Moreno-Ajona, Pablo Irimia, José Antonio Rodríguez, María José García-Velloso, Jesús López-Fidalgo, Leopoldo Fernández-Alonso, Lukasz Grochowitz, Roberto Muñoz, Pablo Domínguez, Jaime Gállego-Culleré and Eduardo Martínez-Vila

    Citation: BMC Cardiovascular Disorders 2020 20:93

    Content type: Research article

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  16. The effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet o...

    Authors: Weihao Wang, Jianan Li, Xiaoxi Chen, Miao Yu, Qi Pan and Lixin Guo

    Citation: BMC Cardiovascular Disorders 2020 20:82

    Content type: Research article

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  17. Tobacco smoke is one of the most significant risk factors for cardiovascular diseases and damages in the myocardial tissue directly. Cardiac magnetic resonance (CMR) has been used and is a promising tool to ev...

    Authors: Ana Natália Ribeiro Batista, Thais Garcia, Estefânia Aparecida Thomé Franco, Paula Schmidt Azevedo, Mauricio Fregonesi Barbosa, Leonardo Antonio Mamede Zornoff, Marcos Ferreira Minicucci, Sergio Alberto Rupp de Paiva, José William Zucchi, Irma de Godoy and Suzana Erico Tanni

    Citation: BMC Cardiovascular Disorders 2020 20:66

    Content type: Research article

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  18. According to the World Health Organization, cardiovascular diseases (CVDs) are the leading non-communicable cause of death. Awareness of the individual risk profile is crucial to implement a healthy lifestyle ...

    Authors: Benoît Bernar, Nina Gande, Katharina A. Stock, Anna Staudt, Raimund Pechlaner, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Michael Knoflach and Ursula Kiechl-Kohlendorfer

    Citation: BMC Cardiovascular Disorders 2020 20:59

    Content type: Study protocol

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  19. Although the Melanocortin-4 Receptor (MC4R) gene rs17782313 C/T has been consistently related to obesity risk, the interaction between MC4R polymorphism and diet quality indices on cardio-metabolic risk factor...

    Authors: Mahdieh Khodarahmi, Houman Kahroba, Mohammad Asghari Jafarabadi, Mehran Mesgari-Abbasi and Mahdieh Abbasalizad Farhangi

    Citation: BMC Cardiovascular Disorders 2020 20:57

    Content type: Research article

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  20. To investigate the influence of hyperhomocysteinemia (HHcy) and metabolic syndrome (MetS) on left ventricular hypertrophy (LVH) in residents in rural Northeast China.

    Authors: Shasha Yu, Yintao Chen, Hongmei Yang, Xiaofan Guo, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2020 20:44

    Content type: Research article

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  21. Hypertension is a major cardiovascular illness worldwide with many underlying causes. The role of trace elements selenium, copper, and zinc in hypertension is uncertain. The objective of this study was to eval...

    Authors: Mrigendra M. Bastola, Craig Locatis, Richard Maisiak and Paul Fontelo

    Citation: BMC Cardiovascular Disorders 2020 20:45

    Content type: Research article

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  22. Although, in-part through an impact on left ventricular mass (LVM), resistin (an adipokine) may contribute to heart failure, whether this is explained by the adverse effects of resistin on aortic stiffness and...

    Authors: Glenda Norman, Gavin R. Norton, Vernice Peterson, Monica Gomes, Carlos D. Libhaber, Pinhas Sareli and Angela J. Woodiwiss

    Citation: BMC Cardiovascular Disorders 2020 20:35

    Content type: Research article

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  23. Platelets in patients with type 2 diabetes mellitus (DM2) are characterized by increased activation and aggregation, which tends to be associated with a high morbidity and mortality due to cardiovascular disea...

    Authors: Ai-ming Zhou, Yi-jia Xiang, En-qian Liu, Chang-hong Cai, Yong-hui Wu, Le-bing Yang and Chun-lai Zeng

    Citation: BMC Cardiovascular Disorders 2020 20:15

    Content type: Research article

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  24. Liver disorders may be associated with normal pulmonary hemodynamic, hepatopulmonary syndrome (HPS), or portopulmonary hypertension (POPH). In this study, we aimed to investigate the effect of the severity of ...

    Authors: Ali Sepehrinezhad, Amirreza Dehghanian, Ali Rafati and Farzaneh Ketabchi

    Citation: BMC Cardiovascular Disorders 2020 20:13

    Content type: Research article

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  25. This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in mainten...

    Authors: Chang Liu, Zi-Ning Yan, Li Fan, Jun Huang, Dan Shen and Xiang-Ting Song

    Citation: BMC Cardiovascular Disorders 2020 20:126

    Content type: Research article

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  26. Inflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet ag...

    Authors: Yanhua Zhen, Zhihui Chang, Zhaoyu Liu and Jiahe Zheng

    Citation: BMC Cardiovascular Disorders 2020 20:9

    Content type: Research article

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  27. Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in ...

    Authors: Joey Junarta, Nina Hojs, Robin Ramphul, Racquel Lowe-Jones, Juan C. Kaski and Debasish Banerjee

    Citation: BMC Cardiovascular Disorders 2020 20:6

    Content type: Research article

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  28. A number of published literature has reported that, physiologically, heart rate variability (HRV) in patients with postural orthostatic tachycardia syndrome (POTS) to be greatly confounded by age, sex, race, p...

    Authors: Joel Swai, Zixuan Hu, Xiexiong Zhao, Tibera Rugambwa and Gui Ming

    Citation: BMC Cardiovascular Disorders 2019 19:320

    Content type: Research article

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  29. Serum immunoglobulins (Igs) play a critical role in modulating the immune response by neutralizing pathogens, although little is known about the effect of Igs in development of atherosclerotic cardiovascular d...

    Authors: Dee Lin, Mary Barna Bridgeman and Luigi Brunetti

    Citation: BMC Cardiovascular Disorders 2019 19:319

    Content type: Research article

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  30. Coronary artery disease (CAD) and plasma lipid levels are highly correlated, indicating the presence of common pathways between them. Nevertheless, the molecular pathways underlying the pathogenic comorbiditie...

    Authors: Liuying Chen, Yinghao Yao, Chaolun Jin, Shen Wu, Qiang Liu, Jingjing Li, Yunlong Ma, Yizhou Xu and Yigang Zhong

    Citation: BMC Cardiovascular Disorders 2019 19:310

    Content type: Research article

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  31. Resting heart rate (RHR) is an obtainable, inexpensive, non-invasive test, readily available on any medical document. RHR has been established as a risk factor for cardiovascular morbidity, is related to other...

    Authors: Michal Ehrenwald, Asaf Wasserman, Shani Shenhar-Tsarfaty, David Zeltser, Limor Friedensohn, Itzhak Shapira, Shlomo Berliner and Ori Rogowski

    Citation: BMC Cardiovascular Disorders 2019 19:307

    Content type: Research article

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  32. Due to epidemiological transitions, Sub-Saharan Africa is facing a growing burden of non-communicable diseases, including cardiovascular diseases (CVDs). Among their risk factors, hypertension is a major deter...

    Authors: Ileana Desormais, Salimanou Ariyoh Amidou, Yessito Corine Houehanou, Stephan Dismand Houinato, Gwladys Nadia Gbagouidi, Pierre Marie Preux, Victor Aboyans and Philippe Lacroix

    Citation: BMC Cardiovascular Disorders 2019 19:303

    Content type: Research article

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  33. Cardiovascular disease has become a serious public health problem in recent years in China. The aim of the study was to examine sex differences in cardiovascular risk factors and 10-year ischemic cardiovascula...

    Authors: Lihong Yang, Anne F. Fish, Yuanyuan Zhu, Xiaodan Yuan, Jianing Li, Xiaoyun Wang, Li Yuan, Zhumin Jia, Chao Liu, Yunchen Xu and Qingqing Lou

    Citation: BMC Cardiovascular Disorders 2019 19:301

    Content type: Research article

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  34. Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the preva...

    Authors: Qun Ma, Zhao Li, Xiaofan Guo, Liang Guo, Shasha Yu, Hongmei Yang, Lu Zou, Liqiang Zheng, Guowei Pan, Yonghong Zhang and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:276

    Content type: Research article

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  35. Hypertension and arterial vasculopathy may be mutual causes and effects. It is unknown whether carotid intima-media thickness (cIMT) is reliably predictive of the presence of newly developed hypertension in th...

    Authors: Long Zhang, Fangfang Fan, Litong Qi, Jia Jia, Ying Yang, Jianping Li and Yan Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:269

    Content type: Research article

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  36. Cardiovascular disease (CVD) is the primary cause of death worldwide, accounting for 31.0% of all deaths and more than 18 million deaths annually. The 2008 World Health Report indicated that 144 (35%) of the 4...

    Authors: Ranya A. Ghamri, Nada S. Alzahrani, Amal M. Alharthi, Hana J. Gadah, Bayan G. Badoghaish and Azzah A. Alzahrani

    Citation: BMC Cardiovascular Disorders 2019 19:268

    Content type: Research article

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  37. Increasing evidence has been presented which suggests that left ventricular (LV) diastolic dysfunction may play an important role in the development of atrial fibrillation (AF). However, the potential for LV d...

    Authors: Fengjiao Chen, Qinliang Sun, Hairu Li, Shaohui Qu, Weidong Yu, Shuangquan Jiang and Jiawei Tian

    Citation: BMC Cardiovascular Disorders 2019 19:257

    Content type: Research article

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  38. Heart failure (HF) is a major public health problem with increasing prevalence worldwide. It is associated with high mortality and poor quality of life due to recurrent and costly hospital admissions. Several ...

    Authors: Luciana Gioli-Pereira, Fabiana G. Marcondes-Braga, Sabrina Bernardez-Pereira, Fernando Bacal, Fábio Fernandes, Alfredo J. Mansur, Alexandre C. Pereira and José E. Krieger

    Citation: BMC Cardiovascular Disorders 2019 19:251

    Content type: Research article

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  39. There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated.

    Authors: Fatemeh Gholami, Ghobad Moradi, Bushra Zareei, Mohammad Aziz Rasouli, Bahram Nikkhoo, Daem Roshani and Ebrahim Ghaderi

    Citation: BMC Cardiovascular Disorders 2019 19:248

    Content type: Research article

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  40. Secondary prevention after an acute myocardial infarction (AMI) reduces morbidity and mortality, but suboptimal secondary prevention of cardiovascular disease is common. Therefore, the present study aimed to i...

    Authors: Maria Sakalaki, Salim Barywani, Annika Rosengren, Lena Björck and Michael Fu

    Citation: BMC Cardiovascular Disorders 2019 19:243

    Content type: Research article

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  41. Hypertension (HTN) is major public health challenge. Data on HTN prevalence and associated risk factors is necessary to better control it. This study aimed at estimating the prevalence of HTN and associated an...

    Authors: Biniem Hassen and Hassen Mamo

    Citation: BMC Cardiovascular Disorders 2019 19:241

    Content type: Research article

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  42. Hypertension management in rural, resource-poor settings is difficult. Detailed understanding of patient, clinician and logistic factors which pose barriers to effective blood pressure control could enable str...

    Authors: J. P. Sibomana, R. L. McNamara and T. D. Walker

    Citation: BMC Cardiovascular Disorders 2019 19:231

    Content type: Research article

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  43. Cardiovascular disease (CVD) is one of the most significant health challenges facing women today. Abuse is a serious gendered issue also affecting the health of women. Despite beginning evidence that abuse may...

    Authors: Kelly A. Scott-Storey, Marilyn Hodgins and Judith Wuest

    Citation: BMC Cardiovascular Disorders 2019 19:224

    Content type: Research article

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  44. Cardiovascular disease (CVD) is the leading cause of death worldwide. Some studies have suggested anassociation between serum uric acid levels and cardiovascular mortality; however, the results have not been s...

    Authors: Fatemeh Rahimi-Sakak, Mahsa Maroofi, Jamal Rahmani, Nick Bellissimo and Azita Hekmatdoost

    Citation: BMC Cardiovascular Disorders 2019 19:218

    Content type: Research article

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  45. Infantile hepatic hemangioma (IHH) is a rare endothelial cell neoplasm, which may be concurrent with severe complications and result in poor outcomes. Moreover, the coexistence of IHH and congenial heart disea...

    Authors: Xin-tong Zhang, Wei-dong Ren, Guang Song, Yang-jie Xiao, Fei-fei Sun and Nan Wang

    Citation: BMC Cardiovascular Disorders 2019 19:216

    Content type: Case report

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  46. Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart. The underlying mechanisms of RIC are still not fully ...

    Authors: Daniel Noronha Osório, Ricardo Viana-Soares, João Pedro Marto, Marcelo D. Mendonça, Hugo P. Silva, Cláudia Quaresma, Miguel Viana-Baptista, Hugo Gamboa and Helena L. A. Vieira

    Citation: BMC Cardiovascular Disorders 2019 19:211

    Content type: Research article

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  47. Little was known about the different predictive power of blood pressure (BP) parameters (SBP, systolic BP; mean arterial pressure, MAP; pulse pressure, PP; and diastolic BP, DBP) and stroke incidence. This stu...

    Authors: Jia Zheng, Zhaoqing Sun, Xiaofan Guo, Yanxia Xie, Yingxian Sun and Liqiang Zheng

    Citation: BMC Cardiovascular Disorders 2019 19:206

    Content type: Research article

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  48. Premature infants may present with damage to the autonomic nervous system (ANS), which may be related to poorer neurological development. Among the techniques used to evaluate the ANS, heart rate variability (...

    Authors: Luiz Fernando Martins de Souza Filho, Jordana Campos Martins de Oliveira, Mayara Kelly Alves Ribeiro, Marcelo Cozac Moura, Nelson David Fernandes, Rafael Dias de Sousa, Gustavo Rodrigues Pedrino and Ana Cristina Silva Rebelo

    Citation: BMC Cardiovascular Disorders 2019 19:198

    Content type: Research article

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  49. Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity (PWV), augmentation index (AIx)) and endothelial dy...

    Authors: Raissa Perrault, Alexander Omelchenko, Carla G. Taylor and Peter Zahradka

    Citation: BMC Cardiovascular Disorders 2019 19:190

    Content type: Research article

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