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Hypertension and cardiovascular risk

This section concerns all aspects of hypertension and peripheral vascular disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology. This section also considers articles concerning patients at high cardiovascular risk, including but not limited to patients with metabolic syndrome and diabetes.

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  1. Platelets in patients with type 2 diabetes mellitus (DM2) are characterized by increased activation and aggregation, which tends to be associated with a high morbidity and mortality due to cardiovascular disea...

    Authors: Ai-ming Zhou, Yi-jia Xiang, En-qian Liu, Chang-hong Cai, Yong-hui Wu, Le-bing Yang and Chun-lai Zeng

    Citation: BMC Cardiovascular Disorders 2020 20:15

    Content type: Research article

    Published on:

  2. Liver disorders may be associated with normal pulmonary hemodynamic, hepatopulmonary syndrome (HPS), or portopulmonary hypertension (POPH). In this study, we aimed to investigate the effect of the severity of ...

    Authors: Ali Sepehrinezhad, Amirreza Dehghanian, Ali Rafati and Farzaneh Ketabchi

    Citation: BMC Cardiovascular Disorders 2020 20:13

    Content type: Research article

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  3. This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in mainten...

    Authors: Chang Liu, Zi-Ning Yan, Li Fan, Jun Huang, Dan Shen and Xiang-Ting Song

    Citation: BMC Cardiovascular Disorders 2020 20:1324

    Content type: Research article

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  4. Inflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet ag...

    Authors: Yanhua Zhen, Zhihui Chang, Zhaoyu Liu and Jiahe Zheng

    Citation: BMC Cardiovascular Disorders 2020 20:9

    Content type: Research article

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  5. Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in ...

    Authors: Joey Junarta, Nina Hojs, Robin Ramphul, Racquel Lowe-Jones, Juan C. Kaski and Debasish Banerjee

    Citation: BMC Cardiovascular Disorders 2020 20:6

    Content type: Research article

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  6. A number of published literature has reported that, physiologically, heart rate variability (HRV) in patients with postural orthostatic tachycardia syndrome (POTS) to be greatly confounded by age, sex, race, p...

    Authors: Joel Swai, Zixuan Hu, Xiexiong Zhao, Tibera Rugambwa and Gui Ming

    Citation: BMC Cardiovascular Disorders 2019 19:320

    Content type: Research article

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  7. Serum immunoglobulins (Igs) play a critical role in modulating the immune response by neutralizing pathogens, although little is known about the effect of Igs in development of atherosclerotic cardiovascular d...

    Authors: Dee Lin, Mary Barna Bridgeman and Luigi Brunetti

    Citation: BMC Cardiovascular Disorders 2019 19:319

    Content type: Research article

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  8. Coronary artery disease (CAD) and plasma lipid levels are highly correlated, indicating the presence of common pathways between them. Nevertheless, the molecular pathways underlying the pathogenic comorbiditie...

    Authors: Liuying Chen, Yinghao Yao, Chaolun Jin, Shen Wu, Qiang Liu, Jingjing Li, Yunlong Ma, Yizhou Xu and Yigang Zhong

    Citation: BMC Cardiovascular Disorders 2019 19:310

    Content type: Research article

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  9. Resting heart rate (RHR) is an obtainable, inexpensive, non-invasive test, readily available on any medical document. RHR has been established as a risk factor for cardiovascular morbidity, is related to other...

    Authors: Michal Ehrenwald, Asaf Wasserman, Shani Shenhar-Tsarfaty, David Zeltser, Limor Friedensohn, Itzhak Shapira, Shlomo Berliner and Ori Rogowski

    Citation: BMC Cardiovascular Disorders 2019 19:307

    Content type: Research article

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  10. Due to epidemiological transitions, Sub-Saharan Africa is facing a growing burden of non-communicable diseases, including cardiovascular diseases (CVDs). Among their risk factors, hypertension is a major deter...

    Authors: Ileana Desormais, Salimanou Ariyoh Amidou, Yessito Corine Houehanou, Stephan Dismand Houinato, Gwladys Nadia Gbagouidi, Pierre Marie Preux, Victor Aboyans and Philippe Lacroix

    Citation: BMC Cardiovascular Disorders 2019 19:303

    Content type: Research article

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  11. Cardiovascular disease has become a serious public health problem in recent years in China. The aim of the study was to examine sex differences in cardiovascular risk factors and 10-year ischemic cardiovascula...

    Authors: Lihong Yang, Anne F. Fish, Yuanyuan Zhu, Xiaodan Yuan, Jianing Li, Xiaoyun Wang, Li Yuan, Zhumin Jia, Chao Liu, Yunchen Xu and Qingqing Lou

    Citation: BMC Cardiovascular Disorders 2019 19:301

    Content type: Research article

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  12. Corrected QT (QTc) interval has been correlated with total and CVD mortality. Although much is known about the relation between prolonged QTc interval and clinical outcome, there is no information on the preva...

    Authors: Qun Ma, Zhao Li, Xiaofan Guo, Liang Guo, Shasha Yu, Hongmei Yang, Lu Zou, Liqiang Zheng, Guowei Pan, Yonghong Zhang and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:276

    Content type: Research article

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  13. Hypertension and arterial vasculopathy may be mutual causes and effects. It is unknown whether carotid intima-media thickness (cIMT) is reliably predictive of the presence of newly developed hypertension in th...

    Authors: Long Zhang, Fangfang Fan, Litong Qi, Jia Jia, Ying Yang, Jianping Li and Yan Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:269

    Content type: Research article

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  14. Cardiovascular disease (CVD) is the primary cause of death worldwide, accounting for 31.0% of all deaths and more than 18 million deaths annually. The 2008 World Health Report indicated that 144 (35%) of the 4...

    Authors: Ranya A. Ghamri, Nada S. Alzahrani, Amal M. Alharthi, Hana J. Gadah, Bayan G. Badoghaish and Azzah A. Alzahrani

    Citation: BMC Cardiovascular Disorders 2019 19:268

    Content type: Research article

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  15. Increasing evidence has been presented which suggests that left ventricular (LV) diastolic dysfunction may play an important role in the development of atrial fibrillation (AF). However, the potential for LV d...

    Authors: Fengjiao Chen, Qinliang Sun, Hairu Li, Shaohui Qu, Weidong Yu, Shuangquan Jiang and Jiawei Tian

    Citation: BMC Cardiovascular Disorders 2019 19:257

    Content type: Research article

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  16. Heart failure (HF) is a major public health problem with increasing prevalence worldwide. It is associated with high mortality and poor quality of life due to recurrent and costly hospital admissions. Several ...

    Authors: Luciana Gioli-Pereira, Fabiana G. Marcondes-Braga, Sabrina Bernardez-Pereira, Fernando Bacal, Fábio Fernandes, Alfredo J. Mansur, Alexandre C. Pereira and José E. Krieger

    Citation: BMC Cardiovascular Disorders 2019 19:251

    Content type: Research article

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  17. There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated.

    Authors: Fatemeh Gholami, Ghobad Moradi, Bushra Zareei, Mohammad Aziz Rasouli, Bahram Nikkhoo, Daem Roshani and Ebrahim Ghaderi

    Citation: BMC Cardiovascular Disorders 2019 19:248

    Content type: Research article

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  18. Secondary prevention after an acute myocardial infarction (AMI) reduces morbidity and mortality, but suboptimal secondary prevention of cardiovascular disease is common. Therefore, the present study aimed to i...

    Authors: Maria Sakalaki, Salim Barywani, Annika Rosengren, Lena Björck and Michael Fu

    Citation: BMC Cardiovascular Disorders 2019 19:243

    Content type: Research article

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  19. Hypertension (HTN) is major public health challenge. Data on HTN prevalence and associated risk factors is necessary to better control it. This study aimed at estimating the prevalence of HTN and associated an...

    Authors: Biniem Hassen and Hassen Mamo

    Citation: BMC Cardiovascular Disorders 2019 19:241

    Content type: Research article

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  20. Hypertension management in rural, resource-poor settings is difficult. Detailed understanding of patient, clinician and logistic factors which pose barriers to effective blood pressure control could enable str...

    Authors: J. P. Sibomana, R. L. McNamara and T. D. Walker

    Citation: BMC Cardiovascular Disorders 2019 19:231

    Content type: Research article

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  21. Cardiovascular disease (CVD) is one of the most significant health challenges facing women today. Abuse is a serious gendered issue also affecting the health of women. Despite beginning evidence that abuse may...

    Authors: Kelly A. Scott-Storey, Marilyn Hodgins and Judith Wuest

    Citation: BMC Cardiovascular Disorders 2019 19:224

    Content type: Research article

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  22. Cardiovascular disease (CVD) is the leading cause of death worldwide. Some studies have suggested anassociation between serum uric acid levels and cardiovascular mortality; however, the results have not been s...

    Authors: Fatemeh Rahimi-Sakak, Mahsa Maroofi, Jamal Rahmani, Nick Bellissimo and Azita Hekmatdoost

    Citation: BMC Cardiovascular Disorders 2019 19:218

    Content type: Research article

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  23. Infantile hepatic hemangioma (IHH) is a rare endothelial cell neoplasm, which may be concurrent with severe complications and result in poor outcomes. Moreover, the coexistence of IHH and congenial heart disea...

    Authors: Xin-tong Zhang, Wei-dong Ren, Guang Song, Yang-jie Xiao, Fei-fei Sun and Nan Wang

    Citation: BMC Cardiovascular Disorders 2019 19:216

    Content type: Case report

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  24. Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart. The underlying mechanisms of RIC are still not fully ...

    Authors: Daniel Noronha Osório, Ricardo Viana-Soares, João Pedro Marto, Marcelo D. Mendonça, Hugo P. Silva, Cláudia Quaresma, Miguel Viana-Baptista, Hugo Gamboa and Helena L. A. Vieira

    Citation: BMC Cardiovascular Disorders 2019 19:211

    Content type: Research article

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  25. Little was known about the different predictive power of blood pressure (BP) parameters (SBP, systolic BP; mean arterial pressure, MAP; pulse pressure, PP; and diastolic BP, DBP) and stroke incidence. This stu...

    Authors: Jia Zheng, Zhaoqing Sun, Xiaofan Guo, Yanxia Xie, Yingxian Sun and Liqiang Zheng

    Citation: BMC Cardiovascular Disorders 2019 19:206

    Content type: Research article

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  26. Premature infants may present with damage to the autonomic nervous system (ANS), which may be related to poorer neurological development. Among the techniques used to evaluate the ANS, heart rate variability (...

    Authors: Luiz Fernando Martins de Souza Filho, Jordana Campos Martins de Oliveira, Mayara Kelly Alves Ribeiro, Marcelo Cozac Moura, Nelson David Fernandes, Rafael Dias de Sousa, Gustavo Rodrigues Pedrino and Ana Cristina Silva Rebelo

    Citation: BMC Cardiovascular Disorders 2019 19:198

    Content type: Research article

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  27. Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity (PWV), augmentation index (AIx)) and endothelial dy...

    Authors: Raissa Perrault, Alexander Omelchenko, Carla G. Taylor and Peter Zahradka

    Citation: BMC Cardiovascular Disorders 2019 19:190

    Content type: Research article

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  28. The patient self-management (PSM) is an effective approach for controlling the international normalized ratio, INR, within the therapeutic range. Nevertheless, most of the literature derives from randomized cl...

    Authors: Bárbara Menéndez-Jándula, José Antonio García-Erce, Clara Zazo and Luis Larrad-Mur

    Citation: BMC Cardiovascular Disorders 2019 19:186

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:263

  29. Atrial fibrillation (AF) significantly increases the risk of ischemic stroke depending on various risk factors. The CHA2DS2-VASc score is used widely to improve stratification of AF-related stroke to identify for...

    Authors: Chen-Di Cheng, Xiang Gu, Hong-Xiao Li, Ruo-Yu Duan, Lei Sun, Yi Zhang, Zheng-Yu Bao, Jian-Hua Shen, Fu-Kun Chen and Ye Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:178

    Content type: Case report

    Published on:

  30. With aging of the population, screening and prevention health programs for blood donors will increasingly be a priority. We aimed at: assessing the 10 year-cardiovascular disease (CVD) risk in blood donors, ac...

    Authors: Francesco Vadini, Francesca Santilli, Giuseppe Casalini, Mario dell’Isola, Ornella Iuliani, Damiano D’Ardes, Luisa Lattanzio, Marta Di Nicola, Giancarlo Di Iorio and Patrizia Accorsi

    Citation: BMC Cardiovascular Disorders 2019 19:177

    Content type: Research article

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  31. An estimated 55% of older adults in Africa have systemic hypertension, a major risk factor for stroke, heart failure and dementia in the region. The risk factors associated with hypertension in this population...

    Authors: William Kofi Bosu, Justice Moses Kwaku Aheto, Eugenio Zucchelli and Siobhan Theresa Reilly

    Citation: BMC Cardiovascular Disorders 2019 19:173

    Content type: Research article

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  32. Improving clinical practice aimed at controlling hypertension is a pending issue in health systems. One of the methods currently used for this purpose is self blood pressure measurement (SBPM) whose use increa...

    Authors: Arleen De León-Robert, Juan José Gascón-Cánovas, José Joaquín Antón-Botella, Isabel María Hidalgo-García, Carmen López-Alegría, Yoalys Dilvani Pérez-Cabrera and Heidy Merari Campusano-Castellanos

    Citation: BMC Cardiovascular Disorders 2019 19:171

    Content type: Research article

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  33. Microparticles are procoagulant membrane vesicles that play role in endothelium dysfunction pathogenesis and are increased in hypertension, acute/chronic vascular pathological events. Here; we aimed to compare...

    Authors: Hanife Usta Atmaca, Feray Akbas and Hale Aral

    Citation: BMC Cardiovascular Disorders 2019 19:164

    Content type: Research article

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  34. Non-traumatic chest pain (NTCP) is a common reason for emergency department (ED) attendance in high-income countries, with the primary concern focused on life threatening cardiovascular diseases. There is gene...

    Authors: Amour S. Mohamed, Hendry R. Sawe, Biita Muhanuzi, Nafsa R. Marombwa, Kilalo Mjema and Ellen J. Weber

    Citation: BMC Cardiovascular Disorders 2019 19:158

    Content type: Research article

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  35. Genetic and environment play a significant role in the etiology of essential hypertension (EH). Recently STK39 rs3754777, ATP2B1 rs2681472 and rs17249754 have been associated with BP variation and hypertension. I...

    Authors: Herman Karim Sombié, Jonas Koudougou Kologo, Daméhan Tchelougou, Serge Yannick Ouédraogo, Abdoul Karim Ouattara, Tegwindé Rebecca Compaoré, Bolni Marius Nagalo, Abel Pegdwendé Sorgho, Issoufou Nagabila, Serge Théophile Soubeïga, Florencia Wendkuuni Djigma, Albert Théophane Yonli, Patrice Zabsonré, Hassanata Millogo and Jacques Simporé

    Citation: BMC Cardiovascular Disorders 2019 19:155

    Content type: Research article

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  36. We investigated changes of cortical thickness and its association with cognitive performance in patients with high-grade carotid artery stenosis without ischemic brain lesions.

    Authors: Alina Nickel, Simon Kessner, Andreas Niebuhr, Julian Schröder, Caroline Malherbe, Felix Fischer, Marlene Heinze, Bastian Cheng, Jens Fiehler, Hans Pinnschmidt, Axel Larena-Avellaneda, Christian Gerloff and Götz Thomalla

    Citation: BMC Cardiovascular Disorders 2019 19:154

    Content type: Research article

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  37. Fatty acid-binding protein 4 (FABP4) (also known as adipocyte FABP or adipocyte P2) is expressed in adipocytes, macrophages, and capillary endothelial cells. Previous studies have shown associations among plas...

    Authors: Chao-Ping Wang, Chia-Chang Hsu, Wei-Chin Hung, Teng-Hung Yu, Cheng-Ching Wu, I-Ting Tsai, Wei-Hua Tang, Fu-Mei Chung, Jer-Yiing Houng, Yau-Jiunn Lee and Yung-Chuan Lu

    Citation: BMC Cardiovascular Disorders 2019 19:153

    Content type: Research article

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  38. Although invasively measured blood pressure (invBP) is regarded as a “gold standard” in critically ill cardiac patients, the non-invasive BP is still widely used, at least at the initiation of medical care. Th...

    Authors: Jitka Seidlerová, Pavlína Tůmová, Richard Rokyta and Milan Hromadka

    Citation: BMC Cardiovascular Disorders 2019 19:150

    Content type: Research article

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  39. CD36 is associated with regulation of lipid metabolism, atherosclerosis, and blood pressure. Moreover, its variation may be involved in the development of hypertension and/or coronary artery disease (CAD). The...

    Authors: Mohammad Amin Momeni-Moghaddam, Gholamreza Asadikaram, Hamed Akbari, Moslem Abolhassani, Mohammad Masoumi, Zahra Nadimy and Mohammad Khaksari

    Citation: BMC Cardiovascular Disorders 2019 19:140

    Content type: Research article

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  40. Type 2 diabetes mellitus (T2DM) is one of the most prevalent cardiac and cerebrovascular risk factors. The study aimed to find a new way to investigate left ventricle (LV) systolic dysfunction in T2DM patients...

    Authors: Jun Huang, Hai-Ling Hu, Zi-Ning Yan, Li Fan, Yi-Fei Rui, Dan Shen and Jie Li

    Citation: BMC Cardiovascular Disorders 2019 19:137

    Content type: Research article

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  41. Effects of β-blockers on outcomes in patients with chronic heart failure (CHF) and atrial fibrillation (AF) is still in controversy.

    Authors: Tianyu Xu, Yuli Huang, Haobin Zhou, Yujia Bai, Xingfu Huang, Yunzhao Hu, Dingli Xu, Yuhui Zhang and Jian Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:135

    Content type: Research article

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  42. Bone morphogenetic protein9 (BMP9) has been reported to have a role in vascular development. However, there is still a lack of information regarding the association between circulating BMP9 levels and cardiova...

    Authors: Rui Liu, Wenjing Hu, Xiaoqiang Li, Danlan Pu, Gangyi Yang, Hua Liu, Minghong Tan and Danping Zhu

    Citation: BMC Cardiovascular Disorders 2019 19:131

    Content type: Research article

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  43. Despite the availability and improvement in diagnostic and therapeutic interventions with proven benefits in reducing cardiovascular morbidity and mortality, control rates of hypertension remain poor and gross...

    Authors: Gebrewahd Bezabh Gebremichael, Kalayou Kidanu Berhe and Teklewoini Mariye Zemichael

    Citation: BMC Cardiovascular Disorders 2019 19:121

    Content type: Research article

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  44. Previous studies reported that low level of oestradiol (E2) was associated with higher risk of cardiovascular disease (CVD). However, little study examined the relationship between E2 and CVD in longevous wome...

    Authors: Qiao Zhu, Yao Yao, Chao-Xue Ning, Xiao-Ping Chen, Fu-Xin Luan, Liang Liu, Qiong Liu, Na Wang, Fu Zhang and Ya-Li Zhao

    Citation: BMC Cardiovascular Disorders 2019 19:115

    Content type: Research article

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  45. Parathyroidectomy has ameliorated cardiovascular risk factors in patients with hypercalcemic primary hyperparathyroidism (PHPT), but the effect of parathyroidectomy on normocalcemic PHPT is not exactly known. ...

    Authors: Selvihan Beysel, Mustafa Caliskan, Muhammed Kizilgul, Mahmut Apaydin, Seyfullah Kan, Mustafa Ozbek and Erman Cakal

    Citation: BMC Cardiovascular Disorders 2019 19:106

    Content type: Research article

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  46. Left ventricle mass (LVM) can be influenced by various conditions including hypertension and/or inherent cardiomyopathies. Dysglycemia is also thought to exert an anabolic effect on heart tissue by hyperinsuli...

    Authors: Gokulan Pararajasingam, Brian Bridal Løgstrup, Dan Eik Høfsten, Thomas Brøcher Christophersen, Søren Auscher, Jørgen Hangaard and Kenneth Egstrup

    Citation: BMC Cardiovascular Disorders 2019 19:103

    Content type: Research article

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  47. Studies from Saudi Arabia have reported a continued increase in the prevalence of cardiovascular diseases and their associated risk factors. The objective of this study was to measure the gender differences in...

    Authors: AlJohara M. AlQuaiz, Amna Rehana Siddiqui, Ambreen Kazi, Mohammad Ali Batais and Ali M. Al-Hazmi

    Citation: BMC Cardiovascular Disorders 2019 19:88

    Content type: Research article

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  48. Ferritin is one of the key proteins that regulate iron homeostasis and is widely available clinical biomarker of iron status. This study aimed to discuss the influence of serum ferritin (SF) on cardiovascular ...

    Authors: Jun-Ru Liu, Yang Liu, Fu-Zai Yin and Bo-Wei Liu

    Citation: BMC Cardiovascular Disorders 2019 19:82

    Content type: Research article

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