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Hypertension and cardiovascular risk

This section concerns all aspects of hypertension and peripheral vascular disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology. This section also considers articles concerning patients at high cardiovascular risk, including but not limited to patients with metabolic syndrome and diabetes.

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  1. Previous renal denervation (RDN) studies showed controversial results in reducing blood pressure. The aim of this study was to provide evidence supporting the effectiveness of laparoscopic-based renal denervat...

    Authors: Chunlai Shao, Yan Zhou, Tao You, Boxin Xue, Pieter R. Stella, Ting Bo Jiang, Zhigang Miao, Longjiang Xu, Yin, Longsheng Lan and Guang Rong

    Citation: BMC Cardiovascular Disorders 2020 20:285

    Content type: Research article

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  2. Participation in an assessment may change health behavior. This “mere-measurement effect” may be used for prevention purposes. However, little is known about whether individuals’ characteristics moderate the e...

    Authors: Lisa Voigt, Antje Ullrich, Sophie Baumann, Marcus Dörr, Ulrich John and Sabina Ulbricht

    Citation: BMC Cardiovascular Disorders 2020 20:272

    Content type: Research article

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  3. Right ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this ...

    Authors: Anna Werther Evaldsson, Anthony Lindholm, Raluca Jumatate, Annika Ingvarsson, Gustav Jan Smith, Johan Waktare, Göran Rådegran, Anders Roijer, Carl Meurling and Ellen Ostenfeld

    Citation: BMC Cardiovascular Disorders 2020 20:259

    Content type: Research article

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  4. BMI has been implicated as a risk factor for heart disease as a whole in multiple studies. Heart attack is one of the common complications of this disease. The aim of this study is to explore if elevated level...

    Authors: Benjamin Adams, Lauren Jacocks and Hui Guo

    Citation: BMC Cardiovascular Disorders 2020 20:258

    Content type: Research article

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  5. The current analysis was performed to estimate the percentage and number of Chinese adults with hypertension and the percentage and number of Chinese adults recommended to receive pharmacological antihypertens...

    Authors: Yundi Jiao, Zhaoqing Sun, Yanxia Xie, Jia Zheng, Zhao Li, Xiaofan Guo, Yue Dai, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2020 20:237

    Content type: Research article

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  6. Atrial fibrillation (AF) is the most common supra ventricular cardiac arrhythmia, which presents with variety of clinical symptoms. Hypertension increases risk of developing Atrial fibrillation by 1.5 fold. To...

    Authors: Smita Bhalia, Pedro Pallangyo, Abuu Dalidali, Saada Salum, Richard Kawajika, Edna Kajuna, Happiness Kusiima, Engerasiya Kifai, Peter Kisenge, Tatizo Waane and Mohamed Janabi

    Citation: BMC Cardiovascular Disorders 2020 20:235

    Content type: Research article

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  7. Preoperative risk prediction in patients at elevated cardiovascular risk shows limited accuracy. Platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) indicate systemic inflammation. Both...

    Authors: Jan Larmann, Jessica Handke, Anna S. Scholz, Sarah Dehne, Christoph Arens, Hans-Jörg Gillmann, Florian Uhle, Johann Motsch, Markus A. Weigand and Henrike Janssen

    Citation: BMC Cardiovascular Disorders 2020 20:230

    Content type: Research article

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  8. Uncertainty still remains on the correlation of methylenetetrahydrofolate reductase (MTHFR) variant C677T with risk of carotid atherosclerosis (CAS), and there is a lack of reports on C677T/MTHFR in the Asian pop...

    Authors: Xulei Peng, Yongli Zhou, Xiaoxing Wu, Xiaolin Wang, Huili Bai, Yongqiang Li, Zhichao Wang, Xuan Chen and Yonghong Wang

    Citation: BMC Cardiovascular Disorders 2020 20:222

    Content type: Research article

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  9. The effectiveness of a 2015–17 community intervention to reduce cardiovascular disease (CVD) and type 2 diabetes (T2DM) risk factors is assessed in a Sri Lanka adult population, using a before-and-after study ...

    Authors: L. Gamlath, S. Nandasena, P. de Silva, S. Morrell, C. Linhart, S. Lin, A. Sharpe, S. Nathan and R. Taylor

    Citation: BMC Cardiovascular Disorders 2020 20:203

    Content type: Research Article

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  10. Advanced glycation end products (AGEs) are associated with aging, diabetes mellitus (DM), and other chronic diseases. Recently, the accumulation of AGEs can be evaluated by skin autofluorescence (SAF). However...

    Authors: Mitsuhiro Kunimoto, Kazunori Shimada, Miho Yokoyama, Tomomi Matsubara, Tatsuro Aikawa, Shohei Ouchi, Megumi Shimizu, Kosuke Fukao, Tetsuro Miyazaki, Tomoyasu Kadoguchi, Kei Fujiwara, Abidan Abulimiti, Akio Honzawa, Miki Yamada, Akie Shimada, Taira Yamamoto…

    Citation: BMC Cardiovascular Disorders 2020 20:195

    Content type: Research article

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  11. The aim of this study was to evaluate whether serum cystatin C could serve as a predictor of multivessel coronary artery disease identified by coronary angiography in type 2 diabetes patients with normal renal...

    Authors: Shaoyi Wang, Qiaohui Liu, Fangfang Guo, Xiaocong Zhou, Jie Shi and Qing Xie

    Citation: BMC Cardiovascular Disorders 2020 20:183

    Content type: Research article

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  12. Elderly patients have a relatively high cardiovascular risk due to increased arterial stiffness, elevated blood pressure and decreased amounts of elastin in the arteries. The composition of the media layer in ...

    Authors: Ida Åström Malm, Urban Alehagen, Peter Blomstrand, Ulf Dahlström and Rachel De Basso

    Citation: BMC Cardiovascular Disorders 2020 20:180

    Content type: Research article

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  13. Renal denervation (RDN) targeting the sympathetic nerves in the renal arterial adventitia as a treatment of resistant hypertension can cause endothelial injury and vascular wall injury. This study aims to eval...

    Authors: Enyong Su, Linwei Zhao, Xiaohang Yang, Binbin Zhu, Yahui Liu, Wen Zhao, Xianpei Wang, Datun Qi, Lijie Zhu and Chuanyu Gao

    Citation: BMC Cardiovascular Disorders 2020 20:176

    Content type: Research article

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  14. The purpose of the research was to explore the extent of interaction between triglycerides (TG) and serum uric acid (SUA) level with blood pressure (BP) in middle-aged and elderly individuals in China.

    Authors: Lin Zhang, Jin-long Li, Lei-lei Guo, Hong Li, Dan Li and Guang Xu

    Citation: BMC Cardiovascular Disorders 2020 20:174

    Content type: Research article

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  15. In resource poor countries, hypertensive disorders of pregnancy are common and form one of the deadly triads, along with hemorrhage and infection, which contribute greatly to maternal and fetal jeopardy.

    Authors: Mekoya D. Mengistu and Tilahun Kuma

    Citation: BMC Cardiovascular Disorders 2020 20:173

    Content type: Research article

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  16. To study the genetic forms and pathophysiology of arterial hypertension by evaluating plasma renin activity in the Shors, minor indigenous peoples inhabiting the south of Western Siberia.

    Authors: Tatyana Mulerova, Evgenya Uchasova, Michael Ogarkov and Olga Barbarash

    Citation: BMC Cardiovascular Disorders 2020 20:169

    Content type: Research article

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  17. Chest pain is one of the most common complaints among patients presenting to the emergency department (ED). Causes of chest pain can be benign or life threatening, making accurate risk stratification a critica...

    Authors: Nan Liu, Dagang Guo, Zhi Xiong Koh, Andrew Fu Wah Ho, Feng Xie, Takashi Tagami, Jeffrey Tadashi Sakamoto, Pin Pin Pek, Bibhas Chakraborty, Swee Han Lim, Jack Wei Chieh Tan and Marcus Eng Hock Ong

    Citation: BMC Cardiovascular Disorders 2020 20:168

    Content type: Research article

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  18. Patient self-management (PSM) of vitamin K antagonists (VKA) seems a very promising model of care for oral anticoagulation in terms of efficacy and safety. In comparison with other management models of VKA the...

    Authors: M. Corrochano, B. Jiménez, J. Millón, I. Gich, M. Rambla, E. Gil, P. Caparrós, R. Macho and J. C. Souto

    Citation: BMC Cardiovascular Disorders 2020 20:166

    Content type: Research article

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  19. Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality o...

    Authors: Tora Hagsund, Sven-Erik Olsson, J. Gustav Smith, Bjarne Madsen Hardig and Henrik Wagner

    Citation: BMC Cardiovascular Disorders 2020 20:165

    Content type: Research article

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  20. Several models have been developed to predict asymptomatic carotid stenosis (ACS), however these models did not pay much attention to people with lower level of stenosis (<50% or carotid plaques, especially in...

    Authors: Junxiong Yin, Chuanyong Yu, Hongxing Liu, Mingyang Du, Feng Sun, Cheng Yu, Lixia Wei, Chongjun Wang and Xiaoshan Wang

    Citation: BMC Cardiovascular Disorders 2020 20:164

    Content type: Research article

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  21. The COngenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry is the first registry for congenital heart disease (CHD) and CHD-related pulmonary hypertension (PH) in adults in Indonesia...

    Authors: Lucia Kris Dinarti, Anggoro Budi Hartopo, Arditya Damar Kusuma, Muhammad Gahan Satwiko, Muhammad Reyhan Hadwiono, Aditya Doni Pradana and Dyah Wulan Anggrahini

    Citation: BMC Cardiovascular Disorders 2020 20:163

    Content type: Research article

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  22. Hypertensive disorders of pregnancy (HDP) is one of the leading causes of maternal and neonatal mortality, increasing the long-term incidence of cardiovascular diseases. Preeclampsia and gestational hypertensi...

    Authors: Yamin Hou, Lin Yun, Lihua Zhang, Jingru Lin and Rui Xu

    Citation: BMC Cardiovascular Disorders 2020 20:155

    Content type: Research article

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  23. Globally, cardiovascular diseases (CVDs) have continued to ravage the human existence through the premature deaths of its workforce. Despite this burden, many studies in Nigeria have focused on determining the...

    Authors: Olaniyan Akintunde Babatunde, Sunday Olakunle Olarewaju, Adeleye Abiodun Adeomi, Joel Olufunminiyi Akande, Adebobola Bashorun, Chukwuma David Umeokonkwo and James Olusegun Bamidele

    Citation: BMC Cardiovascular Disorders 2020 20:154

    Content type: Research article

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  24. We hypothesized that discriminating the early subclinical organ damage would serve as a great opportunity for prevention against atherosclerotic cardiovascular disease (ASCVD). Brachial-ankle pulse wave veloci...

    Authors: Qiaowei Li, Fan Lin, Zhonghai Gao, Feng Huang and Pengli Zhu

    Citation: BMC Cardiovascular Disorders 2020 20:145

    Content type: Research article

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  25. Ascending aortic aneurysms are one of the major causes of mortality. In recent years, there is a growing interest of epicardial adipose tissue (EAT) and related diseases. The aim of this study was to investiga...

    Authors: Onur Argan, Eyup Avci, Tarik Yildirim and Ozgen Safak

    Citation: BMC Cardiovascular Disorders 2020 20:142

    Content type: Research article

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  26. Matrix metalloproteinase-9 (MMP-9) participates in the degradation of components of the extracellular matrix and it is involved in vascular remodeling and vasomotor changes. The aim of this study was to invest...

    Authors: Flavia Mariana Valente, Days Oliveira de Andrade, Luciana Neves Cosenso-Martin, Cláudia Bernardi Cesarino, Sérgio Mussi Guimarães, Victor Beneditti Guimarães, Riccardo Lacchini, José Eduardo Tanus-Santos, Juan Carlos Yugar-Toledo and José Fernando Vilela-Martin

    Citation: BMC Cardiovascular Disorders 2020 20:132

    Content type: Research article

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  27. Hypertension is a major contributing factor to cardiovascular disease and is a leading cause of death in the world. The association between hepatic enzymes and hypertension has been reported in limited studies...

    Authors: Sadaqur Rahman, Shiful Islam, Tangigul Haque, Rahanuma Raihanu Kathak and Nurshad Ali

    Citation: BMC Cardiovascular Disorders 2020 20:128

    Content type: Research article

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  28. To date, the best adiposity index that predicts or associates strongly with hypertension remains controversial. Therefore, we aimed to compare the performance of different adiposity indices [BMI (body mass ind...

    Authors: Lihua Hu, Guiping Hu, Xiao Huang, Wei Zhou, Chunjiao You, Juxiang Li, Ping Li, Yanqing Wu, Qinghua Wu, Zengwu Wang, Runlin Gao, Huihui Bao and Xiaoshu Cheng

    Citation: BMC Cardiovascular Disorders 2020 20:115

    Content type: Research article

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  29. Whether pre-diabetes in the absence of hypertension (HTN) or dyslipidemia (DLP) is a risk factor for occurrence of major adverse cardiovascular events (MACE) is not fully established. We investigated the effec...

    Authors: Nahid Hashemi Madani, Faramarz Ismail-Beigi, Hossein Poustchi, Mahdi Nalini, Sadaf G. Sepanlou, Mojtaba Malek, Mohammad Amin Abbasi, Alireza Khajavi, Mohammad E. Khamseh and Reza Malekzadeh

    Citation: BMC Cardiovascular Disorders 2020 20:113

    Content type: Research article

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  30. Point-of-care haemoglobin meters are attractive solutions to improve timely diagnosis of anaemia in resource-limited settings. However, concerns regarding the accuracy of these meters may affect their adoption...

    Authors: Simeon-Pierre Choukem, Colette Sih, Akondu Tontu Ntumsi, Christian Akem Dimala, Yannick Mboue-Djieka, Eveline D. T. Ngouadjeu and Andre-Pascal Kengne

    Citation: BMC Cardiovascular Disorders 2020 20:111

    Content type: Research article

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  31. Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subject...

    Authors: Sadegh Jafarnejad, Hamed Mirzaei, Cain C. T. Clark, Mohsen Taghizadeh and Armin Ebrahimzadeh

    Citation: BMC Cardiovascular Disorders 2020 20:98

    Content type: Research article

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  32. Major adverse cardiovascular events are the main cause of morbidity and mortality over the long term in patients undergoing carotid endarterectomy. There are few reports assessing the prognostic value of marke...

    Authors: David Moreno-Ajona, Pablo Irimia, José Antonio Rodríguez, María José García-Velloso, Jesús López-Fidalgo, Leopoldo Fernández-Alonso, Lukasz Grochowitz, Roberto Muñoz, Pablo Domínguez, Jaime Gállego-Culleré and Eduardo Martínez-Vila

    Citation: BMC Cardiovascular Disorders 2020 20:93

    Content type: Research article

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  33. The effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet o...

    Authors: Weihao Wang, Jianan Li, Xiaoxi Chen, Miao Yu, Qi Pan and Lixin Guo

    Citation: BMC Cardiovascular Disorders 2020 20:82

    Content type: Research article

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  34. Tobacco smoke is one of the most significant risk factors for cardiovascular diseases and damages in the myocardial tissue directly. Cardiac magnetic resonance (CMR) has been used and is a promising tool to ev...

    Authors: Ana Natália Ribeiro Batista, Thais Garcia, Estefânia Aparecida Thomé Franco, Paula Schmidt Azevedo, Mauricio Fregonesi Barbosa, Leonardo Antonio Mamede Zornoff, Marcos Ferreira Minicucci, Sergio Alberto Rupp de Paiva, José William Zucchi, Irma de Godoy and Suzana Erico Tanni

    Citation: BMC Cardiovascular Disorders 2020 20:66

    Content type: Research article

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  35. According to the World Health Organization, cardiovascular diseases (CVDs) are the leading non-communicable cause of death. Awareness of the individual risk profile is crucial to implement a healthy lifestyle ...

    Authors: Benoît Bernar, Nina Gande, Katharina A. Stock, Anna Staudt, Raimund Pechlaner, Ralf Geiger, Andrea Griesmacher, Stefan Kiechl, Michael Knoflach and Ursula Kiechl-Kohlendorfer

    Citation: BMC Cardiovascular Disorders 2020 20:59

    Content type: Study protocol

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  36. Although the Melanocortin-4 Receptor (MC4R) gene rs17782313 C/T has been consistently related to obesity risk, the interaction between MC4R polymorphism and diet quality indices on cardio-metabolic risk factor...

    Authors: Mahdieh Khodarahmi, Houman Kahroba, Mohammad Asghari Jafarabadi, Mehran Mesgari-Abbasi and Mahdieh Abbasalizad Farhangi

    Citation: BMC Cardiovascular Disorders 2020 20:57

    Content type: Research article

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  37. To investigate the influence of hyperhomocysteinemia (HHcy) and metabolic syndrome (MetS) on left ventricular hypertrophy (LVH) in residents in rural Northeast China.

    Authors: Shasha Yu, Yintao Chen, Hongmei Yang, Xiaofan Guo, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2020 20:44

    Content type: Research article

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  38. Hypertension is a major cardiovascular illness worldwide with many underlying causes. The role of trace elements selenium, copper, and zinc in hypertension is uncertain. The objective of this study was to eval...

    Authors: Mrigendra M. Bastola, Craig Locatis, Richard Maisiak and Paul Fontelo

    Citation: BMC Cardiovascular Disorders 2020 20:45

    Content type: Research article

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  39. Although, in-part through an impact on left ventricular mass (LVM), resistin (an adipokine) may contribute to heart failure, whether this is explained by the adverse effects of resistin on aortic stiffness and...

    Authors: Glenda Norman, Gavin R. Norton, Vernice Peterson, Monica Gomes, Carlos D. Libhaber, Pinhas Sareli and Angela J. Woodiwiss

    Citation: BMC Cardiovascular Disorders 2020 20:35

    Content type: Research article

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  40. Platelets in patients with type 2 diabetes mellitus (DM2) are characterized by increased activation and aggregation, which tends to be associated with a high morbidity and mortality due to cardiovascular disea...

    Authors: Ai-ming Zhou, Yi-jia Xiang, En-qian Liu, Chang-hong Cai, Yong-hui Wu, Le-bing Yang and Chun-lai Zeng

    Citation: BMC Cardiovascular Disorders 2020 20:15

    Content type: Research article

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  41. Liver disorders may be associated with normal pulmonary hemodynamic, hepatopulmonary syndrome (HPS), or portopulmonary hypertension (POPH). In this study, we aimed to investigate the effect of the severity of ...

    Authors: Ali Sepehrinezhad, Amirreza Dehghanian, Ali Rafati and Farzaneh Ketabchi

    Citation: BMC Cardiovascular Disorders 2020 20:13

    Content type: Research article

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  42. This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in mainten...

    Authors: Chang Liu, Zi-Ning Yan, Li Fan, Jun Huang, Dan Shen and Xiang-Ting Song

    Citation: BMC Cardiovascular Disorders 2020 20:126

    Content type: Research article

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  43. Inflammatory reaction is an essential factor in the occurrence, development and prognosis of femoropopliteal disease (FPD). The ratio of platelets to lymphocytes (PLR) is a new indicator reflecting platelet ag...

    Authors: Yanhua Zhen, Zhihui Chang, Zhaoyu Liu and Jiahe Zheng

    Citation: BMC Cardiovascular Disorders 2020 20:9

    Content type: Research article

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  44. Kidney transplant patients suffer from vascular abnormalities and high cardiovascular event rates, despite initial improvements post-transplantation. The nature of the progression of vascular abnormalities in ...

    Authors: Joey Junarta, Nina Hojs, Robin Ramphul, Racquel Lowe-Jones, Juan C. Kaski and Debasish Banerjee

    Citation: BMC Cardiovascular Disorders 2020 20:6

    Content type: Research article

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  45. A number of published literature has reported that, physiologically, heart rate variability (HRV) in patients with postural orthostatic tachycardia syndrome (POTS) to be greatly confounded by age, sex, race, p...

    Authors: Joel Swai, Zixuan Hu, Xiexiong Zhao, Tibera Rugambwa and Gui Ming

    Citation: BMC Cardiovascular Disorders 2019 19:320

    Content type: Research article

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  46. Serum immunoglobulins (Igs) play a critical role in modulating the immune response by neutralizing pathogens, although little is known about the effect of Igs in development of atherosclerotic cardiovascular d...

    Authors: Dee Lin, Mary Barna Bridgeman and Luigi Brunetti

    Citation: BMC Cardiovascular Disorders 2019 19:319

    Content type: Research article

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