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Epidemiology

This section concerns the epidemiology of cardiovascular disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Identification of early signs of atherosclerosis in young adults have the potential to guide early interventions to prevent later cardiovascular disease. We therefore analyzed measures of vascular structure an...

    Authors: Paul Pettersson-Pablo, Yang Cao, Torbjörn Bäckström, Torbjörn K. Nilsson and Anita Hurtig-Wennlöf

    Citation: BMC Cardiovascular Disorders 2020 20:77

    Content type: Research article

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  2. Long-term exposure to pollution has been shown to increase risk of cardiovascular disease (CVD) and mortality, and may contribute to the increased risk of CVD among individuals with higher social risk.

    Authors: Ann Canterbury, Justin B. Echouffo-Tcheugui, Daniel Shpilsky, Aryan Aiyer, Steven E. Reis and Sebhat Erqou

    Citation: BMC Cardiovascular Disorders 2020 20:76

    Content type: Research article

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  3. The relative importance of lifestyle, medical and psychosocial factors on the risk of recurrent major cardiovascular (CV) events (MACE) in coronary patients’ needs to be identified. The main objective of this ...

    Authors: E. Sverre, K. Peersen, H. Weedon-Fekjær, J. Perk, E. Gjertsen, E. Husebye, L. Gullestad, T. Dammen, J. E. Otterstad and J. Munkhaugen

    Citation: BMC Cardiovascular Disorders 2020 20:61

    Content type: Research article

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  4. Several inherited cardiac diseases may lead to sudden cardiac death (SCD) a devastating event in the families. It is crucial to establish a post mortem diagnosis to facilitate relevant work-up and treatment of...

    Authors: Puriya Daniel Yazdanfard, Alex Hørby Christensen, Jacob Tfelt-Hansen, Henning Bundgaard and Bo Gregers Winkel

    Citation: BMC Cardiovascular Disorders 2020 20:58

    Content type: Research article

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  5. Postcardiotomy cardiogenic shock (PCS) that is refractory to inotropic support remains a major concern in cardiac surgery and is almost universally fatal unless treated with mechanical support. While reported ...

    Authors: Mariusz Kowalewski, Giuseppe Maria Raffa, Kamil Zieliński, Musab Alanazi, Martijn Gilbers, Sam Heuts, Ehsan Natour, Elham Bidar, Rick Schreurs, Thijs Delnoij, Rob Driessen, Jan-Willem Sels, Marcel van de Poll, Paul Roekaerts, Paolo Meani, Jos Maessen…

    Citation: BMC Cardiovascular Disorders 2020 20:10

    Content type: Research article

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  6. Congenital heart diseases (CHD) are among the most common congenital malformations. It is estimated that the incidence of CHD is constant worldwide, but data are rare for most African countries including Tanza...

    Authors: Antke Zuechner, Tumaini Mhada, Naizihijwa G. Majani, Godwin G. Sharau, William Mahalu and Matthias W. Freund

    Citation: BMC Cardiovascular Disorders 2019 19:291

    Content type: Research article

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  7. AAA is a disease affecting predominantly male patients ≥65 years and its dreaded complications such as rupture led to population-based screening programs as preventive measure. Nonetheless, the supposed preval...

    Authors: Anna Hohneck, Michael Keese, Gerhard Ruemenapf, Klaus Amendt, Hannelore Muertz, Katharina Janda, Ibrahim Akin, Martin Borggrefe and Martin Sigl

    Citation: BMC Cardiovascular Disorders 2019 19:284

    Content type: Research article

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  8. In spite of the important role of Apolipoprotein-M (ApoM) and Sphingosine-1-Phosphate (S1P) played in atherosclerosis (AS), there was few related research reporting ApoM and S1P complex (ApoM-S1P) on biologica...

    Authors: Yang Liu and Li Tie

    Citation: BMC Cardiovascular Disorders 2019 19:279

    Content type: Research article

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  9. To estimate the prevalence of elevated blood glucose level (EBG, including type 2 diabetes mellitus and impaired fasting glucose), and its association with non-valvular atrial fibrillation (NVAF) in Guangzhou,...

    Authors: Lu Fu, Hai Deng, Wei-dong Lin, Shang-fei He, Fang-zhou Liu, Yang Liu, Xian-zhang Zhan, Xian-hong Fang, Hong-tao Liao, Wei Wei, Zi-li Liao, Li-hong Tang, Zu-yi Fu, Mu-rui Zheng, Shu-lin Wu and Yu-mei Xue

    Citation: BMC Cardiovascular Disorders 2019 19:270

    Content type: Research article

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  10. Hypertension is an established risk factor for the development of atrial fibrillation (AF). We evaluated the association and population impact of hypertension, defined using the new 2017 guidelines, on risk of...

    Authors: Anas Rattani, J’Neka S. Claxton, Mohammed K. Ali, Lin Y. Chen, Elsayed Z. Soliman and Alonso Alvaro

    Citation: BMC Cardiovascular Disorders 2019 19:262

    Content type: Research article

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  11. Cardiovascular disease (CVD) imposes much mortality and morbidity worldwide. The use of “deep learning”, advancements in genomics, metabolomics, proteomics and devices like wearables have the potential to unea...

    Authors: Jonathan Yap, Weng Khong Lim, Anders Sahlén, Calvin Woon-Loong Chin, Kenneth Michael Yun-Chi Chew, Sonia Davila, John Allen, Vera Goh, Swee Yaw Tan, Patrick Tan, Carolyn S. P. Lam, Stuart Alexander Cook and Khung Keong Yeo

    Citation: BMC Cardiovascular Disorders 2019 19:259

    Content type: Study protocol

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  12. The new ACC/AHA hypertension guideline lower the definition of hypertension from 140/90 mmHg to 130/80 mmHg and eliminate the category of prehypertension thus increasing the prevalence of hypertension. A purpo...

    Authors: Yanxia Xie, Mingfeng Ma, Zhao Li, Xiaofan Guo, Guozhe Sun, Zhaoqing Sun, Jia Zheng, Yingxian Sun and Liqiang Zheng

    Citation: BMC Cardiovascular Disorders 2019 19:258

    Content type: Research article

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  13. The risk of sudden cardiac death (SCD) is known to be dynamic. However, the accuracy of a dynamic SCD prediction is unknown. We aimed to measure the dynamic predictive accuracy of ECG biomarkers of SCD and com...

    Authors: Erick A. Perez-Alday, Aron Bender, David German, Srini V. Mukundan, Christopher Hamilton, Jason A. Thomas, Yin Li-Pershing and Larisa G. Tereshchenko

    Citation: BMC Cardiovascular Disorders 2019 19:255

    Content type: Research article

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  14. Individuals with established cardiovascular disease (CVD) and risk factors such as age, smoking, hypertension, and diabetes mellitus are at an increased risk of recurrent cardiovascular events and death. The i...

    Authors: Romona D. Govender, Saif Al-Shamsi, Elpidoforos S. Soteriades and Dybesh Regmi

    Citation: BMC Cardiovascular Disorders 2019 19:253

    Content type: Research article

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  15. The independent association of neck circumference (NC) on elevated blood pressure is still uncertain in adults of China. The aim of this study is to explore such association and investigate the predictive valu...

    Authors: Huijing He, Li Pan, Feng Liu, Jingang Ma, Li Wang, Zhiping Hu, Yajun Li and Guangliang Shan

    Citation: BMC Cardiovascular Disorders 2019 19:244

    Content type: Research article

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  16. Cardiac rehabilitation (CR) programs provide significant benefit for people with cardiovascular disease. Despite these benefits, such services are not universally available. We designed and evaluated a nationa...

    Authors: Bonnie J. Wakefield, Kariann Drwal, Monica Paez, Sara Grover, Carrie Franciscus, Heather Schacht Reisinger, Peter J. Kaboli and Ramzi El Accaoui

    Citation: BMC Cardiovascular Disorders 2019 19:242

    Content type: Research article

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  17. Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat di...

    Authors: Angela A. Mulligan, Marleen A. H. Lentjes, Robert N. Luben, Nicholas J. Wareham and Kay-Tee Khaw

    Citation: BMC Cardiovascular Disorders 2019 19:238

    Content type: Research article

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  18. The risk of peripheral artery disease (PAD) in patients with diabetes mellitus (DM) and coronary artery disease (CAD) is an important and inadequately addressed issue. Our aim is to examine the impact of DM on...

    Authors: Sadaf Kamil, Thomas S. G. Sehested, Nicholas Carlson, Kim Houlind, Jens F. Lassen, Casper N. Bang, Helena Dominguez, Christian T. Pedersen and Gunnar H. Gislason

    Citation: BMC Cardiovascular Disorders 2019 19:234

    Content type: Research article

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  19. First-degree atrioventricular block (AVB) has traditionally been regarded as a benign condition but recent studies have challenged this conception. Prevalence of 1–2% have been reported in developed countries ...

    Authors: Zhi Du, Liying Xing, Min Lin, Yuanmeng Tian, Li Jing, Han Yan, Boqiang Zhang, Shuang Liu, Shiwen Yu and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:214

    Content type: Research article

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  20. Smoking is a strong risk factor for cancer and atherosclerosis. Cancer mortality, especially from lung cancer, overtakes cardiovascular (CV) death rate in patients with peripheral arterial disease (PAD). Only ...

    Authors: Alexandra Yannoutsos, Manon Fontaine, Alexandre Galloula, Diane Damotte, Gilles Chatellier, Patrizia Paterlini-Bréchot, Guy Meyer, Jean Pastre, Véronique Duchatelle, Valéria Marini, Karl-Léo Schwering, Isabelle Lazareth, Parinaz Ghaffari, Audrey Stansal, Hélène Sanson, Cécile Labrousse…

    Citation: BMC Cardiovascular Disorders 2019 19:212

    Content type: Study protocol

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  21. Obesity has nearly tripled worldwide during the last four decades, especially in young adults, and is of growing concern since it is a risk factor for cardiovascular diseases (CVD). We explored how different b...

    Authors: Ulrika Fernberg, Jos op ‘t Roodt, Maria Fernström and Anita Hurtig-Wennlöf

    Citation: BMC Cardiovascular Disorders 2019 19:205

    Content type: Research article

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  22. Several studies on the growth rates of abdominal aortic aneurysm (AAA) in Chinese population have been conducted; however, this issue remains unclear. The aim of this study is to systematically review publishe...

    Authors: Tingting Huang, Shuai Liu, Jianhua Huang, Baohui Xu, Yongping Bai and Wei Wang

    Citation: BMC Cardiovascular Disorders 2019 19:204

    Content type: Research article

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  23. This study examines how prevalence and clustering of cardiovascular disease (CVD) risk factors differ by ethnicity and socioeconomic status (SES) among rural southwest Chinese adults.

    Authors: Li Hui-Fang, Le Cai, Xu-Ming Wang and Allison Rabkin Golden

    Citation: BMC Cardiovascular Disorders 2019 19:200

    Content type: Research article

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  24. Cardiovascular (CV) diseases including heart failure are the leading causes of morbidity, with age being the primary risk factor. The combination of age-related organic functional impairment and reduced physic...

    Authors: Jonathan Wagner, Raphael Knaier, Denis Infanger, Konstantin Arbeev, Matthias Briel, Thomas Dieterle, Henner Hanssen, Oliver Faude, Ralf Roth, Timo Hinrichs and Arno Schmidt-Trucksäss

    Citation: BMC Cardiovascular Disorders 2019 19:180

    Content type: Study protocol

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  25. Cardiovascular disease (CVD) is the leading cause of mortality worldwide; however, the epidemiology of CVD among nationals from the United Arab Emirates (UAE) remains unknown. This study aimed to estimate the ...

    Authors: Saif Al-Shamsi, Dybesh Regmi and Romona D. Govender

    Citation: BMC Cardiovascular Disorders 2019 19:148

    Content type: Research article

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  26. Biochemical marker has revolutionized the approach to the diagnosis of heart failure. However, it remains difficult to assess stability of the patient. As such, novel means of stratifying disease severity are ...

    Authors: Chao Gao, Shasha Zhao, Kun Lian, Baibing Mi, Rui Si, Zhijun Tan, Feng Fu, Shuai Wang, Rutao Wang, Xinliang Ma and Ling Tao

    Citation: BMC Cardiovascular Disorders 2019 19:139

    Content type: Research article

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  27. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are assumed to be prognostic factors in many diseases such as inflammatory diseases, cardiovascular diseases and cancer. However, NLR...

    Authors: Lishan Wu, Shan Zou, Cantian Wang, Xuerui Tan and Min Yu

    Citation: BMC Cardiovascular Disorders 2019 19:125

    Content type: Research article

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  28. Despite currently available treatments, the burden of myocardial infarction (MI) morbidity and mortality remains prominent. The aim of this was to investigate the risk of developing subsequent cardiovascular e...

    Authors: Ville Kytö, Tuire Prami, Houssem Khanfir, Pål Hasvold, Eeva Reissell and Juhani Airaksinen

    Citation: BMC Cardiovascular Disorders 2019 19:123

    Content type: Research article

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  29. Sex-based differences in cardiovascular disease (CVD) burden are widely acknowledged, with male sex considered a risk factor in high-income settings. However, these relationships have not been examined in sub-...

    Authors: Itai M. Magodoro, Maggie Feng, Crystal M. North, Dagmar Vořechovská, John D. Kraemer, Bernard Kakuhikire, David Bangsberg, Alexander C. Tsai and Mark J. Siedner

    Citation: BMC Cardiovascular Disorders 2019 19:96

    Content type: Research article

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  30. Depressive symptomatology may act as a barrier to enhance physical activity. This phenomenon is predominantly found in patients with an established cardiovascular disease (CVD) and in female patients. This cro...

    Authors: Retze Achttien, Jan van Lieshout, Michel Wensing, Maria Nijhuis van der Sanden and J. Bart Staal

    Citation: BMC Cardiovascular Disorders 2019 19:95

    Content type: Research article

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  31. Oral anticoagulants can cause potentially serious adverse events. Therefore, before prescribing oral anticoagulants for ischemic stroke prevention in patients with atrial fibrillation (AF), stroke risk assessm...

    Authors: Felix S. Wicke, Martin A. Schaller, Kateryna Karymova, Martin Beyer and Beate S. Müller

    Citation: BMC Cardiovascular Disorders 2019 19:94

    Content type: Research article

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  32. We aimed to compare the characteristics and types of heart failure (HF) patients termed “high-impact users”, with high long-term readmission rates, in different regions in England. This will allow clinical fac...

    Authors: Ahsan Rao, Dani Kim, Ara Darzi, Azeem Majeed, Paul Aylin and Alex Bottle

    Citation: BMC Cardiovascular Disorders 2019 19:86

    Content type: Research article

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  33. The guideline recommendation to not measure carotid intima-media thickness (CIMT) for cardiovascular risk prediction is based on the assessment of just one single carotid segment. We evaluated whether there is...

    Authors: Lara Müller-Scholden, Jan Kirchhof, Caroline Morbach, Margret Breunig, Rudy Meijer, Viktoria Rücker, Theresa Tiffe, Tino Yurdadogan, Martin Wagner, Götz Gelbrich, Michiel L. Bots, Stefan Störk and Peter U. Heuschmann

    Citation: BMC Cardiovascular Disorders 2019 19:84

    Content type: Research article

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  34. While an expanding armamentarium of pharmacologic therapies has contributed to improved outcomes among adults with heart failure (HF) over the past two decades, this has also been accompanied by an increase in...

    Authors: Peter J. Kennel, Jerard Kneifati-Hayek, Joanna Bryan, Samprit Banerjee, Irina Sobol, Mark S. Lachs, Monika M. Safford and Parag Goyal

    Citation: BMC Cardiovascular Disorders 2019 19:76

    Content type: Research article

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  35. South Asians have disproportionately high rates of cardiovascular disease. Dyslipidemia, a contributing factor, may be influenced by lifestyle, which can vary by religious beliefs. Little is known about South ...

    Authors: Grishma Hirode, Eric Vittinghoff, Nazleen H. Bharmal, Namratha R. Kandula and Alka M. Kanaya

    Citation: BMC Cardiovascular Disorders 2019 19:75

    Content type: Research article

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  36. A cross-talk between Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) plays a vital role in aortic pathophysiology. The objective of this study was to evaluate the interactions between TLR4 an...

    Authors: Tan Li, Xu Zhang, Liang Sang, Xin-tong Li, Hai-yang Sun, Jun Yang and Yuan Yuan

    Citation: BMC Cardiovascular Disorders 2019 19:72

    Content type: Research article

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  37. Hypertriglyceridemia is strongly associated with the risks of cardiovascular disease, coronary heart disease, and metabolic syndrome. The relationship between hypertriglyceridemia or high triglyceride levels a...

    Authors: Jeong Hee Chi, Moon Sun Shin and Bum Ju Lee

    Citation: BMC Cardiovascular Disorders 2019 19:66

    Content type: Research article

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  38. Differences in adherence may represent drug properties (e.g. dosing interval) or patient experiences while on treatment. Adherence to direct oral anticoagulants (DOACs) in nonvalvular atrial fibrillation (NVAF...

    Authors: Phuong N. Pham and Joshua D. Brown

    Citation: BMC Cardiovascular Disorders 2019 19:64

    Content type: Research article

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  39. Despite the recommendations of statins treatment for secondary prevention of atherosclerotic cardiovascular disease (ASCVD), treatment adherence and persistence are still a concern. This study examined the rea...

    Authors: Shu-ting Chen, Shih-ting Huang, Wen-Yi Shau, Chao-Lun Lai, Jim Z. Li, Selwyn Fung, Vicki C. Tse and Mei-Shu Lai

    Citation: BMC Cardiovascular Disorders 2019 19:62

    Content type: Research article

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  40. We aimed to investigate the role of hypercoagulability on the risk of lifetime cardiovascular recurrences after myocardial infarction or ischaemic stroke.

    Authors: Alberto Maino, Ale Algra, Flora Peyvandi, Frits Richard Rosendaal and Bob Siegerink

    Citation: BMC Cardiovascular Disorders 2019 19:55

    Content type: Research article

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  41. The Swedish healthcare system aims to provide equal access to care to all residents yet evidence suggests that patients with low socioeconomic status are less likely to receive new drugs. Associations between ...

    Authors: Venkatesh Kumar Gurusamy, Gunnar Brobert, Pareen Vora and Leif Friberg

    Citation: BMC Cardiovascular Disorders 2019 19:43

    Content type: Research article

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  42. The aim of this study is to investigate if IL8 levels were associated with incident cardiovascular (CV) events (CVE) and mortality (all-cause, CV, and cancer) in a cohort of 60 years old men and women from Sto...

    Authors: Ilais Moreno Velásquez, Ashwini Gajulapuri, Karin Leander, Anita Berglund, Ulf de Faire and Bruna Gigante

    Citation: BMC Cardiovascular Disorders 2019 19:34

    Content type: Research article

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  43. This study aimed to assess the trends in the prevalence of electrocardiographic (ECG) abnormalities from 1986 to 2015 and impact of ECG abnormalities on risk of death from cardiovascular diseases (CVD) in the ...

    Authors: Abdonas Tamosiunas, Janina Petkeviciene, Ricardas Radisauskas, Gailute Bernotiene, Dalia Luksiene, Mindaugas Kavaliauskas, Irena Milvidaitė and Dalia Virviciute

    Citation: BMC Cardiovascular Disorders 2019 19:30

    Content type: Research article

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  44. According to several studies in population of high-income countries (HIC), patients with Type 2 diabetes mellitus (DM) have a considerably higher risk of cardiovascular morbidity and mortality. However, it is ...

    Authors: Pablo Miranda-Machado, Fernando Salcedo-Mejía, Justo Paz Wilches, Juan Fernandez-Mercado, Fernando De la Hoz-Restrepo and Nelson Alvis-Guzmán

    Citation: BMC Cardiovascular Disorders 2019 19:8

    Content type: Research article

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  45. Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying disease. T...

    Authors: Viera Stubnova, Ingrid Os, Aud Høieggen, Marit D. Solbu, Morten Grundtvig, Arne S. Westheim, Dan Atar and Bård Waldum-Grevbo

    Citation: BMC Cardiovascular Disorders 2019 19:4

    Content type: Research article

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