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Epidemiology

This section concerns the epidemiology of cardiovascular disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Content type: Research article

    Cardiovascular disease (CVD) is the leading cause of mortality worldwide; however, the epidemiology of CVD among nationals from the United Arab Emirates (UAE) remains unknown. This study aimed to estimate the ...

    Authors: Saif Al-Shamsi, Dybesh Regmi and Romona D. Govender

    Citation: BMC Cardiovascular Disorders 2019 19:148

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  2. Content type: Research article

    Biochemical marker has revolutionized the approach to the diagnosis of heart failure. However, it remains difficult to assess stability of the patient. As such, novel means of stratifying disease severity are ...

    Authors: Chao Gao, Shasha Zhao, Kun Lian, Baibing Mi, Rui Si, Zhijun Tan, Feng Fu, Shuai Wang, Rutao Wang, Xinliang Ma and Ling Tao

    Citation: BMC Cardiovascular Disorders 2019 19:139

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  3. Content type: Research article

    Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are assumed to be prognostic factors in many diseases such as inflammatory diseases, cardiovascular diseases and cancer. However, NLR...

    Authors: Lishan Wu, Shan Zou, Cantian Wang, Xuerui Tan and Min Yu

    Citation: BMC Cardiovascular Disorders 2019 19:125

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  4. Content type: Research article

    Despite currently available treatments, the burden of myocardial infarction (MI) morbidity and mortality remains prominent. The aim of this was to investigate the risk of developing subsequent cardiovascular e...

    Authors: Ville Kytö, Tuire Prami, Houssem Khanfir, Pål Hasvold, Eeva Reissell and Juhani Airaksinen

    Citation: BMC Cardiovascular Disorders 2019 19:123

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  5. Content type: Research article

    Sex-based differences in cardiovascular disease (CVD) burden are widely acknowledged, with male sex considered a risk factor in high-income settings. However, these relationships have not been examined in sub-...

    Authors: Itai M. Magodoro, Maggie Feng, Crystal M. North, Dagmar Vořechovská, John D. Kraemer, Bernard Kakuhikire, David Bangsberg, Alexander C. Tsai and Mark J. Siedner

    Citation: BMC Cardiovascular Disorders 2019 19:96

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  6. Content type: Research article

    Depressive symptomatology may act as a barrier to enhance physical activity. This phenomenon is predominantly found in patients with an established cardiovascular disease (CVD) and in female patients. This cro...

    Authors: Retze Achttien, Jan van Lieshout, Michel Wensing, Maria Nijhuis van der Sanden and J. Bart Staal

    Citation: BMC Cardiovascular Disorders 2019 19:95

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  7. Content type: Research article

    Oral anticoagulants can cause potentially serious adverse events. Therefore, before prescribing oral anticoagulants for ischemic stroke prevention in patients with atrial fibrillation (AF), stroke risk assessm...

    Authors: Felix S. Wicke, Martin A. Schaller, Kateryna Karymova, Martin Beyer and Beate S. Müller

    Citation: BMC Cardiovascular Disorders 2019 19:94

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  8. Content type: Research article

    We aimed to compare the characteristics and types of heart failure (HF) patients termed “high-impact users”, with high long-term readmission rates, in different regions in England. This will allow clinical fac...

    Authors: Ahsan Rao, Dani Kim, Ara Darzi, Azeem Majeed, Paul Aylin and Alex Bottle

    Citation: BMC Cardiovascular Disorders 2019 19:86

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  9. Content type: Research article

    The guideline recommendation to not measure carotid intima-media thickness (CIMT) for cardiovascular risk prediction is based on the assessment of just one single carotid segment. We evaluated whether there is...

    Authors: Lara Müller-Scholden, Jan Kirchhof, Caroline Morbach, Margret Breunig, Rudy Meijer, Viktoria Rücker, Theresa Tiffe, Tino Yurdadogan, Martin Wagner, Götz Gelbrich, Michiel L. Bots, Stefan Störk and Peter U. Heuschmann

    Citation: BMC Cardiovascular Disorders 2019 19:84

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  10. Content type: Research article

    While an expanding armamentarium of pharmacologic therapies has contributed to improved outcomes among adults with heart failure (HF) over the past two decades, this has also been accompanied by an increase in...

    Authors: Peter J. Kennel, Jerard Kneifati-Hayek, Joanna Bryan, Samprit Banerjee, Irina Sobol, Mark S. Lachs, Monika M. Safford and Parag Goyal

    Citation: BMC Cardiovascular Disorders 2019 19:76

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  11. Content type: Research article

    South Asians have disproportionately high rates of cardiovascular disease. Dyslipidemia, a contributing factor, may be influenced by lifestyle, which can vary by religious beliefs. Little is known about South ...

    Authors: Grishma Hirode, Eric Vittinghoff, Nazleen H. Bharmal, Namratha R. Kandula and Alka M. Kanaya

    Citation: BMC Cardiovascular Disorders 2019 19:75

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  12. Content type: Research article

    A cross-talk between Toll-like receptor 4 (TLR4) and matrix metalloproteinase 9 (MMP9) plays a vital role in aortic pathophysiology. The objective of this study was to evaluate the interactions between TLR4 an...

    Authors: Tan Li, Xu Zhang, Liang Sang, Xin-tong Li, Hai-yang Sun, Jun Yang and Yuan Yuan

    Citation: BMC Cardiovascular Disorders 2019 19:72

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  13. Content type: Research article

    Hypertriglyceridemia is strongly associated with the risks of cardiovascular disease, coronary heart disease, and metabolic syndrome. The relationship between hypertriglyceridemia or high triglyceride levels a...

    Authors: Jeong Hee Chi, Moon Sun Shin and Bum Ju Lee

    Citation: BMC Cardiovascular Disorders 2019 19:66

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  14. Content type: Research article

    Differences in adherence may represent drug properties (e.g. dosing interval) or patient experiences while on treatment. Adherence to direct oral anticoagulants (DOACs) in nonvalvular atrial fibrillation (NVAF...

    Authors: Phuong N. Pham and Joshua D. Brown

    Citation: BMC Cardiovascular Disorders 2019 19:64

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  15. Content type: Research article

    Despite the recommendations of statins treatment for secondary prevention of atherosclerotic cardiovascular disease (ASCVD), treatment adherence and persistence are still a concern. This study examined the rea...

    Authors: Shu-ting Chen, Shih-ting Huang, Wen-Yi Shau, Chao-Lun Lai, Jim Z. Li, Selwyn Fung, Vicki C. Tse and Mei-Shu Lai

    Citation: BMC Cardiovascular Disorders 2019 19:62

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  16. Content type: Research article

    We aimed to investigate the role of hypercoagulability on the risk of lifetime cardiovascular recurrences after myocardial infarction or ischaemic stroke.

    Authors: Alberto Maino, Ale Algra, Flora Peyvandi, Frits Richard Rosendaal and Bob Siegerink

    Citation: BMC Cardiovascular Disorders 2019 19:55

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  17. Content type: Research article

    The Swedish healthcare system aims to provide equal access to care to all residents yet evidence suggests that patients with low socioeconomic status are less likely to receive new drugs. Associations between ...

    Authors: Venkatesh Kumar Gurusamy, Gunnar Brobert, Pareen Vora and Leif Friberg

    Citation: BMC Cardiovascular Disorders 2019 19:43

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  18. Content type: Research article

    The aim of this study is to investigate if IL8 levels were associated with incident cardiovascular (CV) events (CVE) and mortality (all-cause, CV, and cancer) in a cohort of 60 years old men and women from Sto...

    Authors: Ilais Moreno Velásquez, Ashwini Gajulapuri, Karin Leander, Anita Berglund, Ulf de Faire and Bruna Gigante

    Citation: BMC Cardiovascular Disorders 2019 19:34

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  19. Content type: Research article

    This study aimed to assess the trends in the prevalence of electrocardiographic (ECG) abnormalities from 1986 to 2015 and impact of ECG abnormalities on risk of death from cardiovascular diseases (CVD) in the ...

    Authors: Abdonas Tamosiunas, Janina Petkeviciene, Ricardas Radisauskas, Gailute Bernotiene, Dalia Luksiene, Mindaugas Kavaliauskas, Irena Milvidaitė and Dalia Virviciute

    Citation: BMC Cardiovascular Disorders 2019 19:30

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  20. Content type: Research article

    According to several studies in population of high-income countries (HIC), patients with Type 2 diabetes mellitus (DM) have a considerably higher risk of cardiovascular morbidity and mortality. However, it is ...

    Authors: Pablo Miranda-Machado, Fernando Salcedo-Mejía, Justo Paz Wilches, Juan Fernandez-Mercado, Fernando De la Hoz-Restrepo and Nelson Alvis-Guzmán

    Citation: BMC Cardiovascular Disorders 2019 19:8

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  21. Content type: Research article

    Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying disease. T...

    Authors: Viera Stubnova, Ingrid Os, Aud Høieggen, Marit D. Solbu, Morten Grundtvig, Arne S. Westheim, Dan Atar and Bård Waldum-Grevbo

    Citation: BMC Cardiovascular Disorders 2019 19:4

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  22. Content type: Research article

    Sleep-related investigations in acute myocardial infarction (AMI) patients are rare. The aim of this study was to examine sex-specific associations of patient-reported sleep disturbances within 4 weeks before ...

    Authors: Franziska Nairz, Christa Meisinger, Inge Kirchberger, Margit Heier, Christian Thilo, Bernhard Kuch, Annette Peters and Ute Amann

    Citation: BMC Cardiovascular Disorders 2018 18:235

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  23. Content type: Research article

    The health-related quality of life (HRQoL) is an important treatment goal that could serve as low-cost prognostication tool in resource poor settings.

    Authors: Samson Okello, Fardous Charles Abeya, Boniface Amanee Elias Lumori, Suzan Joan Akello, Christopher Charles Moore, Brian H. Annex and Andrew J. Buda

    Citation: BMC Cardiovascular Disorders 2018 18:232

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  24. Content type: Research article

    Physical activity programs (PAP) in patients with cardiovascular disease require evidence of cost-utility. To assess improvement in health-related quality of life (QoL) and reduction of health care consumption...

    Authors: Laurent Bailly, Philippe Mossé, Stéphane Diagana, Marion Fournier, Fabienne d’Arripe-Longueville, Odile Diagana, Jocelyn Gal, Jean Grebet, Mario Moncada, Jean-Jacques Domerego, Rémi Radel, Roxane Fabre, Alain Fuch and Christian Pradier

    Citation: BMC Cardiovascular Disorders 2018 18:225

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  25. Content type: Research article

    The rate of incidentally diagnosed congenital heart disease (CHD) in adulthood has not been reported. The aim of this study was to investigate the detection rate of CHD in adults by routine, general health che...

    Authors: Eun Min Kwag, Ju Suk Lee and Sung Hoon Kim

    Citation: BMC Cardiovascular Disorders 2018 18:223

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  26. Content type: Research article

    Self-administered health-status questionnaires are important tools in epidemiology. The objective of the presented validation study is to measure the agreement between breast cancer patients’ self-reports and ...

    Authors: Hiltrud Merzenich, Maria Blettner, Dorothea Niehoff, Lukas Schwentner, Marcus Schmidt, Margit Schmitt and Daniel Wollschläger

    Citation: BMC Cardiovascular Disorders 2018 18:218

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  27. Content type: Research article

    Implantable cardioverter defibrillator (ICD) implantation is associated with driving restrictions which may have profound effects on the patient’s life. However, there is limited patient-reported data on the i...

    Authors: Jenny Bjerre, Simone Hofman Rosenkranz, Anne Mielke Christensen, Morten Schou, Christian Jøns, Gunnar Gislason and Anne-Christine Ruwald

    Citation: BMC Cardiovascular Disorders 2018 18:212

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  28. Content type: Research article

    The objective of our study was to compare resource use and clinical outcomes among atrial fibrillation (AF) patients who underwent catheter ablation versus antiarrhythmic drug (AAD) treatment.

    Authors: Julian W. E. Jarman, Wajid Hussain, Tom Wong, Vias Markides, Jamie March, Laura Goldstein, Ray Liao, Iftekhar Kalsekar, Abhishek Chitnis and Rahul Khanna

    Citation: BMC Cardiovascular Disorders 2018 18:211

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  29. Content type: Research article

    The current study evaluated time trends of statin use and incidence of recurrent CVD in secondary prevention from 1999 to 2013 and investigated which factors were associated with statin use in secondary preven...

    Authors: Nele Laleman, Séverine Henrard, Marjan van den Akker, Geert Goderis, Frank Buntinx, Gijs Van Pottelbergh and Bert Vaes

    Citation: BMC Cardiovascular Disorders 2018 18:209

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  30. Content type: Research article

    Few studies have suggested that patients with myocardial infarction (MI) may be at increased risk of cancer, but further large register-based studies are needed to evaluate this subject. The aim of this study ...

    Authors: Morten Malmborg, Christine Benn Christiansen, Michelle D. Schmiegelow, Christian Torp-Pedersen, Gunnar Gislason and Morten Schou

    Citation: BMC Cardiovascular Disorders 2018 18:198

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  31. Content type: Research article

    The association between pre-operative cardiac catheterization and cardiac surgery associated acute kidney injury (CSA-AKI) has been reported inconsistently. The purpose of this study is to evaluate the effect ...

    Authors: Wuhua Jiang, Jiawei Yu, Jiarui Xu, Bo Shen, Yimei Wang, Zhe Luo, Chunsheng Wang, Xiaoqiang Ding and Jie Teng

    Citation: BMC Cardiovascular Disorders 2018 18:191

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  32. Content type: Research article

    Recent studies have shown a significant role of the endocannabinoid system, apelin and S100A6 protein in the regulation of cardiovascular system functioning. The aim of the study was to compare and evaluate th...

    Authors: Irena Kasacka, Żaneta Piotrowska, Anna Filipek and Wojciech Lebkowski

    Citation: BMC Cardiovascular Disorders 2018 18:190

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  33. Content type: Research article

    Individuals with prehypertension are at higher risk of developing hypertension and cardiovascular diseases, while the interaction between factors may aggravate prehypertension risk. Therefore, this study aimed...

    Authors: Jian Song, Xue Chen, Yingying Zhao, Jing Mi, Xuesen Wu and Huaiquan Gao

    Citation: BMC Cardiovascular Disorders 2018 18:182

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  34. Content type: Research article

    Many previous clinical studies have reported that prolongation of the QT interval corrected for heart rate (QTc) is associated with an increased risk of sudden cardiac death and all-cause mortality. This study...

    Authors: Yintao Chen, Xiaofan Guo, Guozhe Sun, Zhao Li, Liqiang Zheng and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2018 18:175

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  35. Content type: Research article

    Left ventricular (LV) hypertrophy and changes in LV geometry are associated with increased cardiovascular mortality. Subjects with type 2 diabetes have an increased risk of such alterations in cardiac morpholo...

    Authors: Susanne Rospleszcz, Anina Schafnitzel, Wolfgang Koenig, Roberto Lorbeer, Sigrid Auweter, Cornelia Huth, Wolfgang Rathmann, Margit Heier, Birgit Linkohr, Christa Meisinger, Holger Hetterich, Fabian Bamberg and Annette Peters

    Citation: BMC Cardiovascular Disorders 2018 18:162

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  36. Content type: Study protocol

    Heart failure (HF) and frailty often co-exist, and frailty in HF results in a poor prognosis. However, in Asian populations, prognostic criteria are needed to examine the effect of frailty on HF. Therefore, we...

    Authors: Sumio Yamada, Takuji Adachi, Hideo Izawa, Toyoaki Murohara and Takaaki Kondo

    Citation: BMC Cardiovascular Disorders 2018 18:159

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  37. Content type: Research article

    Ischemic Heart Disease (IHD) is the first ranked among most common causes of death involving cardiovascular and other diseases. The information on the prevalence of IHD in Thailand is lacking especially among ...

    Authors: Boonsub Sakboonyarat and Ram Rangsin

    Citation: BMC Cardiovascular Disorders 2018 18:151

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  38. Content type: Research article

    Nonalcoholic fatty liver disease (NAFLD) refers to fatty infiltration of liver in the absence of excessive alcohol abuse. However, the problem that whether NAFLD is correlated with subclinical atherosclerosis ...

    Authors: Jilin Zheng, Yong Zhou, Kuo Zhang, Yu Qi, Shimin An, Siyuan Wang, Xingquan Zhao and Yi-Da Tang

    Citation: BMC Cardiovascular Disorders 2018 18:147

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  39. Content type: Research article

    Inflammation is a common feature of both peripheral arterial disease (PAD) and periodontitis. Some studies have evaluated the association between PAD and periodontitis. However, there is still no specialized m...

    Authors: Shuo Yang, Li Sheng Zhao, Chuan Cai, Quan Shi, Ning Wen and Juan Xu

    Citation: BMC Cardiovascular Disorders 2018 18:141

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  40. Content type: Research article

    The EPICOR Asia (long-tErm follow-uP of antithrombotic management patterns In acute CORonary syndrome patients in Asia) study (NCT01361386) was an observational study of patients hospitalized for acute coronar...

    Authors: Stephen Jan, Stephen W-L. Lee, Jitendra P. S. Sawhney, Tiong K. Ong, Chee Tang Chin, Hyo-Soo Kim, Rungroj Krittayaphong, Vo T. Nhan, Stuart J. Pocock, Ana M. Vega, Nobuya Hayashi and Yong Huo

    Citation: BMC Cardiovascular Disorders 2018 18:139

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  41. Content type: Research article

    The large global burden of rheumatic heart disease (RHD) has come to light in recent years following robust epidemiologic studies. As an operational research component of a broad program aimed at primary and s...

    Authors: John Musuku, Mark E. Engel, Patrick Musonda, Joyce Chipili Lungu, Elizabeth Machila, Sherri Schwaninger, Agnes Mtaja, Evans Mulendele, Dorothy Kavindele, Jonathan Spector, Brigitta Tadmor, Marcelo M. Gutierrez, Joris Van Dam, Laurence Colin, Aidan Long, Mark C. Fishman…

    Citation: BMC Cardiovascular Disorders 2018 18:135

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  42. Content type: Research article

    The incidence and mortality of cardiovascular diseases (CVDs) in low and middle income countries (LMICs) have been increasing, while access to CVDs medicines is suboptimal. We assessed selection of essential m...

    Authors: Y. T. Bazargani, M. Ugurlu, A. de Boer, H. G. M. Leufkens and A. K. Mantel-Teeuwisse

    Citation: BMC Cardiovascular Disorders 2018 18:126

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  43. Content type: Research article

    In the present study, the association of the cardio-metabolic risk factors and the status of single-child family were studied in a national representative sample of Iranian children and adolescents.

    Authors: Roya Kelishadi, Mostafa Qorbani, Fatemeh Rezaei, Mohammad Esmaeil Motlagh, Shirin Djalalinia, Hasan Ziaodini, Majzoubeh Taheri, Fatemeh Ochi, Gita Shafiee, Tahereh Aminaei, Armita Mahdavi Gorabi and Ramin Heshmat

    Citation: BMC Cardiovascular Disorders 2018 18:109

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  44. Content type: Research article

    Neck circumference (NC), representing upper body subcutaneous adipose tissue, may be correlated with increased risk of overweight/obesity, obstructive sleep apnoea, and metabolic and cardiovascular disease. Ho...

    Authors: Jingjing Zhang, Qi Guo, Liyuan Peng, Jiamei Li, Ya Gao, Bin Yan, Bangjiang Fang and Gang Wang

    Citation: BMC Cardiovascular Disorders 2018 18:108

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  45. Content type: Research article

    Patient preferences are key parameters to evaluate benefit-harm balance of statins for primary prevention but they are not readily available to guideline developers and decision makers. Our study aimed to elic...

    Authors: Henock G. Yebyo, Hélène E. Aschmann, Tsung Yu and Milo A. Puhan

    Citation: BMC Cardiovascular Disorders 2018 18:97

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  46. Content type: Research article

    The risk factors for peripheral artery disease (PAD) are more common in Indigenous than non-Indigenous Australians, however the presentation and outcome of PAD in Indigenous Australians has not been previously...

    Authors: Tejas P. Singh, Joseph V. Moxon, Genevieve N. Healy, Yvonne Cadet-James and Jonathan Golledge

    Citation: BMC Cardiovascular Disorders 2018 18:94

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  47. Content type: Research article

    The inter-relationships of atrial fibrillation (AF) to retinal vascular occlusions (whether retinal artery occlusion (RAO) or retinal venous occlusion (RVO)) remain unclear. It is unknown if a presentation of ...

    Authors: Christine Benn Christiansen, Christian Torp-Pedersen, Jonas Bjerring Olesen, Gunnar Gislason, Morten Lamberts, Nicholas Carlson, Mathias Buron, Nikolai Juul and Gregory Y. H. Lip

    Citation: BMC Cardiovascular Disorders 2018 18:91

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