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Coronary artery disease

This section concerns all aspects of coronary artery disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Vascular endothelial cell apoptosis is the leading risk factor of atherosclerosis (AS). The purpose of our study was to use a new generation high-throughput transcription factor (TF) detection method to identi...

    Authors: Mangyuan Wang, Fen Liu, Binbin Fang, Qiang Huo and Yining Yang

    Citation: BMC Cardiovascular Disorders 2021 21:448

    Content type: Research article

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  2. Homocysteine (Hcy) is considered to be a risk factor for cardiovascular and cerebrovascular diseases. Few studies have evaluated the distribution of Hcy on a large-scale health examination. Accordingly, this s...

    Authors: Fang Bao, Ming Cui, Xiuying Shi, Shaoqing Ju and Hui Cong

    Citation: BMC Cardiovascular Disorders 2021 21:429

    Content type: Research article

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  3. To explore the characteristics of myocardial textures on coronary computed tomography angiography (CCTA) images in patients with coronary atherosclerotic heart disease, a classification model was established, ...

    Authors: Hengyu Zhao, Lijie Yuan, Zhishang Chen, Yuting Liao and Jiangzhou Lin

    Citation: BMC Cardiovascular Disorders 2021 21:416

    Content type: Research article

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  4. The impact of thrombocytopenia on infection in patients with ST-elevation myocardial infarction (STEMI) remains poorly understood.

    Authors: Litao Wang, Weijiang Su, Jinhua Xue, Xiao Gong, Yining Dai, Jiyan Chen, Ling Xue, Pengcheng He, Yuanhui Liu and Ning Tan

    Citation: BMC Cardiovascular Disorders 2021 21:404

    Content type: Research article

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  5. To investigate the relationship between obstructive sleep apnea (OSA) severity and high-sensitivity C-reactive protein (Hs-CRP), and their respective impact on the clinical outcomes in patients undergoing off-...

    Authors: Mingxin Gao, Kangjun Fan, Wenyuan Yu, Hongli Liu, Yongxiang Wei and Yang Yu

    Citation: BMC Cardiovascular Disorders 2021 21:366

    Content type: Research article

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  6. The interventional treatment of calcified lesions with severe tortuosity in the left anterior descending artery (LAD) was challenging and the report of rotational atherectomy with mother-and-child technique ha...

    Authors: Taichi Kato, Masashi Fujino, Kensuke Takagi and Teruo Noguchi

    Citation: BMC Cardiovascular Disorders 2021 21:360

    Content type: Case report

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  7. Indoleamine 2,3 dioxygenase (IDO), the rate-limiting enzyme in the kynurenine (Kyn) pathway of tryptophan (Trp) degradation, is modulated by inflammation, and is regarded as a key molecule driving immunotolera...

    Authors: Nattawut Wongpraparut, Ploy Pengchata, Sudarat Piyophirapong, Pariya Panchavinnin, Rungtiwa Pongakasira, Noppadol Arechep, Kanda Kasetsinsombat and Kittipong Maneechotesuwan

    Citation: BMC Cardiovascular Disorders 2021 21:353

    Content type: Research article

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  8. Myocardial infarction (MI) contributes to high mortality and morbidity and can also accelerate atherosclerosis, thus inducing recurrent event due to status changing of coronary artery walls or plaques. The res...

    Authors: Qiang Zhang, Yue Zheng, Meng Ning and Tong Li

    Citation: BMC Cardiovascular Disorders 2021 21:344

    Content type: Research article

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  9. Serum free fatty acid (FFA) concentrations are associated with coronary heart disease and diabetes mellitus (DM). Few studies focused on the relationship between serum FFA levels and coronary artery calcificat...

    Authors: Yangxun Xin, Junfeng Zhang, Yuqi Fan and Changqian Wang

    Citation: BMC Cardiovascular Disorders 2021 21:343

    Content type: Research article

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  10. Mobile health-based individualized interventions have shown potential effects in managing cardiovascular risk factors. This study aims to assess whether or not mHealth based individualized interventions delive...

    Authors: Yuling Chen, Meihua Ji, Ying Wu, Ying Deng, Fangqin Wu and Yating Lu

    Citation: BMC Cardiovascular Disorders 2021 21:340

    Content type: Study protocol

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  11. This study was performed to investigate the clinical significance of combined evaluation of both coronary artery disease (CAD) and high-sensitivity cardiac troponin T (hs-cTnT) for prediction of major adverse ...

    Authors: Hang Liao, Huay Cheem Tan, Ziqiong Wang, Xiaoping Chen, Yong He and Sen He

    Citation: BMC Cardiovascular Disorders 2021 21:325

    Content type: Research article

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  12. Recent trials have revealed that sodium-glucose co-transporter 2 inhibitors (SGLT2-i) are effective against hyperglycemia and also reduce micro- and macro-vascular complications in patients with type 2 diabete...

    Authors: Sepehr Gohari, Tara Reshadmanesh, Hadi Khodabandehloo, Mojtaba Fathi, Hassan Ahangar, Shahram Arsang-Jang, Faramarz Ismail-Beigi, Samin Ghanbari, Mohsen Dadashi, Muhammad Javad Muhammadi, Sheida Gohari and Saeid Ghaffari

    Citation: BMC Cardiovascular Disorders 2021 21:318

    Content type: Study protocol

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  13. There are relatively limited data regarding real-world outcomes in very old patients with three-vessel disease (3VD) receiving different therapeutic strategies. This study aimed to perform analysis of long-ter...

    Authors: Deshan Yuan, Sida Jia, Ce Zhang, Lin Jiang, Lianjun Xu, Yin Zhang, Jingjing Xu, Ru Liu, Bo Xu, Rutai Hui, Runlin Gao, Zhan Gao, Lei Song and Jinqing Yuan

    Citation: BMC Cardiovascular Disorders 2021 21:316

    Content type: Research article

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  14. Due to its low incidence and diverse manifestations, paradoxical embolism (PDE) is still under-reported and is not routinely considered in differential diagnoses. Concomitant acute myocardial infarction (AMI) ...

    Authors: Weiwei Chen, Zhixi Yu, Siming Li, Kenji Wagatsuma, Beibei Du and Ping Yang

    Citation: BMC Cardiovascular Disorders 2021 21:313

    Content type: Case report

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  15. Coronary artery-to-pulmonary artery fistula is a rare disorder characterized by abnormal vascular communication between the coronary artery and pulmonary artery. While most patients remain asymptomatic, some m...

    Authors: Xuanqi An, Shaoxian Guo, Huawei Dong, Yida Tang, Lin Li, Xuejing Duan and Shaodong Ye

    Citation: BMC Cardiovascular Disorders 2021 21:273

    Content type: Case report

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  16. Clinical symptoms of patients on dialysis do not match the signs of coronary disease progression, making the prediction of the true progression of their medical condition in clinical settings difficult. Emerge...

    Authors: Hironobu Yamaoka, Taira Yamamoto, Daisuke Endo, Akie Shimada, Satoshi Matsushita, Tohru Asai and Atsushi Amano

    Citation: BMC Cardiovascular Disorders 2021 21:271

    Content type: Case report

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  17. Cardiovascular diseases have become the leading cause of death worldwide, and cardiac hypertrophy is the core mechanism underlying cardiac defect and heart failure. However, the underlying mechanisms of cardia...

    Authors: Yi Wang, Hongjuan Liao, Yueheng Wang, Jinlin Zhou, Feng Wang, Yingxin Xie, Kun Zhao and Weinian Gao

    Citation: BMC Cardiovascular Disorders 2021 21:266

    Content type: Research article

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  18. Accurate prediction of major adverse cardiovascular events (MACEs) is very important for the management of acute coronary syndrome (ACS) patients. We aimed to construct an effective prognostic nomogram for ind...

    Authors: Shuting Kong, Changxi Chen, Gaoshu Zheng, Hui Yao, Junfeng Li, Hong Ye, Xiaobo Wang, Xiang Qu, Xiaodong Zhou, Yucheng Lu and Hao Zhou

    Citation: BMC Cardiovascular Disorders 2021 21:253

    Content type: Research article

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  19. The objective was to assess current training preferences, expertise, and comfort with transfemoral access (TFA) and transradial access (TRA) amongst cardiovascular training fellows and teaching faculty in the ...

    Authors: Khalid Changal, Mubbasher Ameer Syed, Ealla Atari, Salik Nazir, Sameer Saleem, Sajjad Gul, F. N. U. Salman, Asad Inayat and Ehab Eltahawy

    Citation: BMC Cardiovascular Disorders 2021 21:250

    Content type: Research article

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  20. The effect of smoking on coronary vasomotion has been investigated in the past with various imaging techniques in both short- and long-term smokers. Additionally, coronary vasomotion has been shown to be norma...

    Authors: Andreas M. Weng, Herbert Köstler, Thorsten A. Bley and Christian O. Ritter

    Citation: BMC Cardiovascular Disorders 2021 21:237

    Content type: Research article

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  21. The Cathepsins family, including cathepsin B and cathepsin D, potentially affects the entire processes involved in atherosclerosis. Although coronary heart disease (CHD) has been widely studied as the basis of...

    Authors: Jialin Dai, Qiong Zhang, Changwu Wan, Jiangjin Liu, Qiaojun Zhang, Yanni Yu and Jie Wang

    Citation: BMC Cardiovascular Disorders 2021 21:233

    Content type: Research article

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  22. The jailed balloon technique is widely used for coronary bifurcation lesions, but a residual risk of SB occlusion remains, necessitating SB rewiring and further interventions, including balloon inflation or st...

    Authors: Hongbo Yang, Yanan Song, Jiatian Cao, Xueyi Weng, Feng Zhang, Yuxiang Dai, Hao Lu, Chenguang Li, Zheyong Huang, Juying Qian and Junbo Ge

    Citation: BMC Cardiovascular Disorders 2021 21:232

    Content type: Technical advance

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  23. Incretin therapies appear to provide cardioprotection and improve cardiovascular outcomes in patients with diabetes, but the mechanism of this effect remains elusive. We have previously shown that glucagon-lik...

    Authors: Muhammad Aetesam-ur-Rahman, Joel P. Giblett, Bharat Khialani, Stephen Kyranis, Sophie J. Clarke, Tian X. Zhao, Denise M. Braganza, Sarah C. Clarke, Nick E. J. West, Martin R. Bennett and Stephen P. Hoole

    Citation: BMC Cardiovascular Disorders 2021 21:223

    Content type: Research article

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  24. There is limited evidence of Aboriginal and Torres Strait Islander people attending cardiac rehabilitation (CR) programs despite high levels of heart disease. One key enabler for CR attendance is a culturally ...

    Authors: Nicole Freene, Roslyn Brown, Paul Collis, Chris Bourke, Katharine Silk, Alicia Jackson, Rachel Davey and Holly L. Northam

    Citation: BMC Cardiovascular Disorders 2021 21:222

    Content type: Research article

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  25. Circular RNAs have shown important regulatory roles in cardiovascular diseases, containing atherosclerosis (AS). We intended to explore the role of circ_0004104 in AS using oxidized low-density lipoprotein (ox...

    Authors: Chi Zhang, Liyue Wang and Ying Shen

    Citation: BMC Cardiovascular Disorders 2021 21:207

    Content type: Research article

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  26. Several studies have shown that N-terminal pro-B-type natriuretic peptide (NT-proBNP) is strongly correlated with the complexity of coronary artery disease and the prognosis of patients with non-ST segment el...

    Authors: Wen-fei He, Lei Jiang, Yi-yue Chen, Yuan-hui Liu, Peng-yuan Chen, Chong-yang Duan, Li-huan Zeng, Hua-lin Fan, Xue-biao Wei, Wei Guo, Wei Chen, Jun Li, Wen-sheng Li, Zhi-qiang Guo, Zhi-kai Liu, Ning Tan…

    Citation: BMC Cardiovascular Disorders 2021 21:202

    Content type: Research article

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  27. Vitamin D deficiency is associated with cardiovascular diseases, including coronary artery diseases (CAD). As vitamin D manifests its biological function through its vitamin D receptor (VDR), VDR gene polymorp...

    Authors: Damir Raljević, Viktor Peršić, Elitza Markova-Car, Leon Cindrić, Rajko Miškulin, Marta Žuvić and Sandra Kraljević Pavelić

    Citation: BMC Cardiovascular Disorders 2021 21:188

    Content type: Research article

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  28. Smoking, heavy alcohol drinking and drug abuse are detrimental lifestyle factors leading to loss of million years of healthy life annually. One of the major health complications caused by these substances is t...

    Authors: Zahra Jalali, Morteza Khademalhosseini, Narjes Soltani and Ali Esmaeili Nadimi

    Citation: BMC Cardiovascular Disorders 2021 21:185

    Content type: Review

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  29. Coronary chronic total occlusions (CTOs) are related to increased risk of adverse clinical outcomes. The optimal treatment strategy for CTO has not been well established. We sought to examine the impact of CTO...

    Authors: Xuhe Gong, Li Zhou, Xiaosong Ding, Hui Chen and Hongwei Li

    Citation: BMC Cardiovascular Disorders 2021 21:182

    Content type: Research article

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  30. New-onset atrial fibrillation (NOAF) is common during acute myocardial infarction (AMI) and independently associated with worse prognosis. We aimed to validate the discrimination performance of CHA2DS2-VASc sc...

    Authors: Yuan Fu, Yuxia Pan, Yuanfeng Gao, Xinchun Yang and Mulei Chen

    Citation: BMC Cardiovascular Disorders 2021 21:175

    Content type: Research article

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  31. Stent ablation with rotational atherectomy has been considered a bail-out strategy for the treatment of severe stent underexpansion. Only a few reports have yet shown rotational ablation for double-layer metal...

    Authors: Tong Yaliang, Liu Guohui, Zhang Cheng, Du Beibei, Zhao Yanan, He Yuquan and Yang Ping

    Citation: BMC Cardiovascular Disorders 2021 21:173

    Content type: Case report

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  32. The pathophysiology of isolated coronary artery ectasia (CAE) with the coronary slow flow (CSF) phenomenon is still unclear. The purpose of this study was to investigate the risk factors for isolated CAE compl...

    Authors: Zhuoxuan Yang, Jiansong Yuan, JinGang Cui, Hao Guan and Shubin Qiao

    Citation: BMC Cardiovascular Disorders 2021 21:156

    Content type: Research article

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  33. In China, there has been a precipitous increase in the number of percutaneous coronary interventions (PCI) conducted. We sought to characterize the clinical and psychosocial trajectory of PCI patients from the...

    Authors: Xia Liu, Adeleke Fowokan, Sherry L. Grace, Biao Ding, Shu Meng, Xiu Chen, Yinghua Xia and Yaqing Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:148

    Content type: Research article

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  34. The recreational drugs cannabis and nitrous oxide (N2O) are known for pro-atherogenic effects and are associated with an elevated risk of myocardial infarction. These cardiovascular effects might be underestimate...

    Authors: Sarah Bär, Fabien Praz and Lorenz Räber

    Citation: BMC Cardiovascular Disorders 2021 21:147

    Content type: Case report

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  35. The PEGASUS-TIMI 54 trial inclusion criteria effectively identified high-risk patients with recent myocardial infarction (MI) who would benefit from continuing dual antiplatelet therapy (DAPT) with ticagrelor ...

    Authors: Federico Sanchez, Valentina Boasi, Matteo Vercellino, Chiara Tacchi, Pierpaolo Cannarile, Nicoletta Pingelli, Dino Perri, Laura Gomez, Stefano Cattunar and Giovanni Mascelli

    Citation: BMC Cardiovascular Disorders 2021 21:144

    Content type: Research article

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  36. Kounis syndrome is an acute coronary syndrome that appears in the setting of anaphylactic reaction or hypersensitivity. Many drugs and environmental exposures have been identified as potential offenders, and d...

    Authors: Hui-zhu Liang, Hong Zhao, Jian Gao, Cheng-fu Cao and Wei-min Wang

    Citation: BMC Cardiovascular Disorders 2021 21:133

    Content type: Case report

    Published on:

  37. Whether very elderly women with acute coronary syndromes (ACS) should receive aggressive percutaneous coronary intervention (PCI) is still controversial. We assessed the effectiveness and long-term clinical ou...

    Authors: Jia-li Wang, Chun-yan Guo, Hui Chen, Hong-wei Li, Xue-qiao Zhao and Shu-mei Zhao

    Citation: BMC Cardiovascular Disorders 2021 21:122

    Content type: Research article

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  38. Polyarteritis nodosa (PAN) is a relatively rare systemic necrotizing vasculitis that typically affects medium-sized arteries. Although myocardial ischemia may occur due to involvement of the coronary arteries,...

    Authors: Hong Huang, Yanjun Gong, Li Guo and Zhuoli Zhang

    Citation: BMC Cardiovascular Disorders 2021 21:115

    Content type: Case report

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  39. Aerobic exercise improves endothelial function and arterial stiffness after myocardial infarction (MI), but the effects of isometric exercise on cardiovascular parameters are still uncertain. We aimed to asses...

    Authors: Daniel P. Kollet, Ana Beatriz Marenco, Nathan L. Bellé, Eduardo Barbosa, Liliana Boll, Bruna Eibel, Gustavo Waclawovsky and Alexandre Machado Lehnen

    Citation: BMC Cardiovascular Disorders 2021 21:101

    Content type: Research article

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  40. Chronic kidney disease (CKD) are associated with acute myocardial infarction (AMI). High-sensitive cardiac troponin (hs-cTn) has been evidenced to enhance the early diagnostic accuracy of AMI, but hs-cTn level...

    Authors: Daijin Ren, Tianlun Huang, Xin Liu and Gaosi Xu

    Citation: BMC Cardiovascular Disorders 2021 21:100

    Content type: Research article

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  41. The impact of reduction in glycemic excursion on coronary plaques remains unknown. This study aimed to elucidate whether a dipeptidyl peptidase 4 inhibitor could reduce the glycemic excursion and stabilize the...

    Authors: Hiroyuki Yamamoto, Akihide Konishi, Toshiro Shinke, Hiromasa Otake, Masaru Kuroda, Tsuyoshi Osue, Takahiro Sawada, Tomofumi Takaya, Hiroya Kawai, Naoko Hashimoto, Takeshi Ohara, Yushi Hirota, Kazuhiko Sakaguchi, Takashi Omori, Wataru Ogawa and Ken-ichi Hirata

    Citation: BMC Cardiovascular Disorders 2021 21:92

    Content type: Research article

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  42. Coronary artery disease (CAD) remains one of the leading causes of mortality and morbidity worldwide. As oxygen and nutrient supply to the myocardium significantly decrease during ischemic periods, important c...

    Authors: Efstratios Karagiannidis, Georgios Sofidis, Andreas S. Papazoglou, Olga Deda, Eleftherios Panteris, Dimitrios V. Moysidis, Nikolaos Stalikas, Anastasios Kartas, Anastasios Papadopoulos, Leandros Stefanopoulos, Haralambos Karvounis, Helen Gika, Georgios Theodoridis and Georgios Sianos

    Citation: BMC Cardiovascular Disorders 2021 21:79

    Content type: Study protocol

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  43. Serum microRNAs (miRNAs) have been used as novel biomarkers for various diseases, including acute coronary syndrome (ACS). This study aimed to investigate the expression and clinical significance of microRNA-3...

    Authors: Wenqing Zhang, Guannan Chang, Liya Cao and Gang Ding

    Citation: BMC Cardiovascular Disorders 2021 21:74

    Content type: Research article

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  44. Left ventricular negative remodelling after ST-segment elevation myocardial infarction (STEMI) is considered as the major cause for the poor prognosis. But the predisposing factors and potential mechanisms of ...

    Authors: Shuai Meng, Yong Zhu, Kesen Liu, Ruofei Jia, Jing Nan, Maolin Chen, Xuan Lei, Kaiyuan Zou and Zening Jin

    Citation: BMC Cardiovascular Disorders 2021 21:72

    Content type: Research article

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