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Coronary artery disease

Section edited by Fabrizio D'ascenzo
This section concerns all aspects of coronary artery disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    The role of apolipoprotein E gene (APOE) in lipid metabolism has been well established, and APOE is associated with the risk of cardiovascular disease (CVD) and diabetes mellitus (DM). However, the relationshi...

    Authors: Sudong Liu, Jing Liu, Ruiqiang Weng, Xiaodong Gu and Zhixiong Zhong

    Citation: BMC Cardiovascular Disorders 2019 19:213

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  2. Content type: Research article

    The purpose of this study was to analyze cardiopulmonary fitness in Phase I cardiac rehabilitation on the prognosis of patients with ST-Elevation Myocardial Infarction (STEMI) after percutaneous coronary inter...

    Authors: He Cai, Yang Zheng, Zhaoxi Liu, Xinying Zhang, Rongyu Li, Wangshu Shao, Lin Wang, Lin Zou and Pengyu Cao

    Citation: BMC Cardiovascular Disorders 2019 19:210

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  3. Content type: Research article

    Percutaneous coronary intervention for coronary artery bifurcation disease (CABD) remains challenging. In patients of CABD with situations that two-stent strategy is needed, the culotte technique is a widely u...

    Authors: Chih-Feng Chang, Keng-Hao Chang, Chih-Hung Lai, Tzu-Hsiang Lin, Tsun-Jui Liu, Wen-Lieng Lee and Chieh-Shou Su

    Citation: BMC Cardiovascular Disorders 2019 19:208

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  4. Content type: Research article

    The present study aimed to expound the association between the XK related 6 gene (XKR6) rs7819412 single nucleotide polymorphism (SNP) and serum lipid profiles and the risk of coronary artery disease (CAD) and is...

    Authors: Peng-Fei Zheng, Rui-Xing Yin, Guo-Xiong Deng, Yao-Zong Guan, Bi-Liu Wei and Chun-Xiao Liu

    Citation: BMC Cardiovascular Disorders 2019 19:202

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  5. Content type: Research article

    Using 18F-fluorodeoxyglucose (18FDG) positron emission tomography-computed tomography (PET/CT) imaging, we examined the effects of ezetimibe/simvastatin 10/10 mg versus rosuvastatin 10 mg on carotid atherosclerot...

    Authors: Minyoung Oh, Hyunji Kim, Eon Woo Shin, Changhwan Sung, Do-Hoon Kim, Dae Hyuk Moon and Cheol Whan Lee

    Citation: BMC Cardiovascular Disorders 2019 19:201

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  6. Content type: Research article

    This study aimed to investigate the effect of long non-coding RNA nuclear enriched abundant transcript 1 (lnc-NEAT1) on cell proliferation and apoptosis in myocardial ischemia/reperfusion (I/R) injury cells, a...

    Authors: Lingyun Ren, Shanshan Chen, Wei Liu, Pan Hou, Wei Sun and Hong Yan

    Citation: BMC Cardiovascular Disorders 2019 19:192

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  7. Content type: Research article

    Coronary artery aneurysm (CAA) is a rare disease, and there are limited data on prescribing patterns for CAA. The aim of our study was to investigate prescribing patterns for CAA in Taiwan via the National Hea...

    Authors: Chun-Hui Lu, Chih-Wun Fang, Hao-Ming Chen, Yi-Ping Fang, Chein-Tang Fang, Yaw-Bin Huang, Chung-Yu Chen, Kuang-Ming Liao and Shu-Chuan Jennifer Yeh

    Citation: BMC Cardiovascular Disorders 2019 19:188

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  8. Content type: Research article

    It is uncertain whether the coronary lesion with intermediate stenosis is more likely to cause cardiovascular events than a normal or minimal lesion. We conducted a single-center, prospective cohort study to i...

    Authors: Young Hoon Seo, Yong-Kyun Kim, In Geol Song, Ki-Hong Kim, Taek-Geun Kwon and Jang-Ho Bae

    Citation: BMC Cardiovascular Disorders 2019 19:187

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  9. Content type: Research article

    It has been indicated that Angiotensin-Converting Enzyme Insertion/Deletion (ACE I/D) polymorphism (rs4646994) could be regarded as a genetic factor that raises the risk of CAD through its impact on the activi...

    Authors: Negar Nouryazdan, Glavizh Adibhesami, Mehdi Birjandi, Rouhollah Heydari, Banafsheh Yalameha and Gholamreza Shahsavari

    Citation: BMC Cardiovascular Disorders 2019 19:184

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  10. Content type: Research article

    It is well known that the genotype of ALDH2 is associated with coronary artery disease (CAD), and in-stent restenosis (ISR) is a primary complication of percutaneous coronary intervention (PCI), a primary recomme...

    Authors: Lizhi Lv, Weijie Ye, Peiyuan Song, Yubin Chen, Jing Yang, Congmin Zhang, Xiaoping Chen and Fanyan Luo

    Citation: BMC Cardiovascular Disorders 2019 19:176

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  11. Content type: Research article

    In-stent restenosis remains an unresolved issue. Inflammation plays a pivotal role in the process of in-stent restenosis. Significant and positive associations were found between red blood cell distribution width...

    Authors: Ning Geng, Guangsheng Su, Shaojun Wang, Deling Zou, Wenyue Pang and Yingxian Sun

    Citation: BMC Cardiovascular Disorders 2019 19:175

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  12. Content type: Research article

    Aneurysmal subarachnoid hemorrhage is a life- threatening condition with high rate of disability and mortality. Apolipoprotein E (APOE) and Factor XIIIA (F13A) genes are involved in the pathogenetic mechanism of ...

    Authors: S. Arati, G. K. Chetan, M. K. Sibin, Dhananjaya I. Bhat, Vikas Vazhayil and K. V. L. Narasingarao

    Citation: BMC Cardiovascular Disorders 2019 19:170

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  13. Content type: Research article

    The prognostic implication of statin in tolerance (SI) in those with stable CAD remains unclear. We hypothesized that SI is of higher prognostic significance in stable CAD patients with elevated high-sensitive...

    Authors: Jo-Jo Hai, Yuen-Kwun Wong, Chun-Ka Wong, Ka-Chun Un, Pak-Hei Chan, Chung-Wah Siu, Kai-Hang Yiu, Chu-Pak Lau and Hung-Fat Tse

    Citation: BMC Cardiovascular Disorders 2019 19:168

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  14. Content type: Case report

    Autoimmune diseases, such as systemic lupus erythematosus (SLE), are associated with thrombosis and atherosclerosis. Presence of lupus anticoagulant is an independent risk factor for atherosclerotic diseases.

    Authors: Kota Murai, Kenji Sakata, Tadatsugu Gamou, Yoji Nagata, Hayato Tada, Masaya Shimojima, Hirofumi Okada, Kenshi Hayashi and Masa-aki Kawashiri

    Citation: BMC Cardiovascular Disorders 2019 19:167

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  15. Content type: Research article

    Despite of the established effectiveness, the acceptance and adherence of cardiac rehabilitation (CR) remains sub-optimal. Mobile technologies are increasingly used in promoting CR without any firm evidence of...

    Authors: Linqi Xu, Feng Li, Changli Zhou, Jinwei Li, Chengcheng Hong and Qian Tong

    Citation: BMC Cardiovascular Disorders 2019 19:166

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  16. Content type: Research article

    Patients with acute myocardial infarction (AMI) often accompanied by admission hyperglycemia, which usually predicts a poor clinical outcomes for non-diabetes mellitus. Appropriate cut-point to identify high r...

    Authors: Xiao Song Ding, Shan Shan Wu, Hui Chen, Xue Qiao Zhao and Hong Wei Li

    Citation: BMC Cardiovascular Disorders 2019 19:163

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  17. Content type: Research article

    Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation myocardial infar...

    Authors: David Nordlund, Henrik Engblom, Jean-Louis Bonnet, Henrik Steen Hansen, Dan Atar, David Erlinge, Ulf Ekelund, Einar Heiberg, Marcus Carlsson and Håkan Arheden

    Citation: BMC Cardiovascular Disorders 2019 19:161

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  18. Content type: Case report

    Familial hypercholesterolemia (FH) can lead to premature coronary heart disease. Anticardiolipin antibody may be a contributor for thrombosis. Here, we report an adult with possible FH suffered from premature ...

    Authors: Xin Su, Aqian Wang, Hai Zhu, Hongling Su, Yichao Duan, Shanlian Wu, Min Zhang, Yan Huang, Xing Zhou and Yunshan Cao

    Citation: BMC Cardiovascular Disorders 2019 19:156

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  19. Content type: Research article

    Contrast-induced nephropathy (CIN) is common after percutaneous coronary intervention (PCI) and always leads to a poor prognosis. Compared with conventional detection methods, either high-sensitivity C-reactiv...

    Authors: Guoqiang Gu, Xuechao Yuan, Yaqing Zhou, Demin Liu and Wei Cui

    Citation: BMC Cardiovascular Disorders 2019 19:152

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  20. Content type: Research article

    The aim of this study was to investigate the relationship between Talin-1 and stability of carotid atherosclerosis plaque and also find out the role of miRNA, as an upstream regulator, in regulating the expres...

    Authors: Xiaolong Wei, Yudong Sun, Tonglei Han, Jiang Zhu, Yongfu Xie, Shiying Wang, Yani Wu, Yinxing Fan, Xiuli Sun, Jian Zhou, Zhiqing Zhao and Zaiping Jing

    Citation: BMC Cardiovascular Disorders 2019 19:149

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  21. Content type: Research article

    The relationship between vitamin D levels and peripheral arterial disease (PAD) remains unclear. We assessed the association of serum 25-hydroxyvitamin D (25(OH)D) levels with the prevalence of PAD in patients...

    Authors: Jing Yuan, Pu Jia, Lin Hua, Zhong Xin and Jin-Kui Yang

    Citation: BMC Cardiovascular Disorders 2019 19:145

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  22. Content type: Research article

    Using the current meta-analysis as well as systematic review, to determine the curative effect of Nicorandil in comparison of no Nicorandil after elective percutaneous coronary intervention(PCI) on patients.

    Authors: Xiao-Tao Zhao, Chun-Fei Zhang and Qing-Jie Liu

    Citation: BMC Cardiovascular Disorders 2019 19:144

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  23. Content type: Research article

    Cardiovascular diseases remain the top global killer, with nearly 80% of related mortalities occurring in developing countries. Over half of cardiovascular diseases’ mortality is due to coronary heart disease,...

    Authors: Mohannad Eid AbuRuz

    Citation: BMC Cardiovascular Disorders 2019 19:143

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  24. Content type: Research article

    The purpose of this review is to examine the effect of Omega-3 Fatty acids on mortality, morbidity, and adverse events in patients with acute myocardial infarction (AMI).

    Authors: Federico Popoff, Giselle Balaciano, Ariel Bardach, Daniel Comandé, Vilma Irazola, Hugo Norberto Catalano and Ariel Izcovich

    Citation: BMC Cardiovascular Disorders 2019 19:136

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  25. Content type: Research article

    Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and mor...

    Authors: Bjarne Madsen Hardig, Karl B. Kern and Henrik Wagner

    Citation: BMC Cardiovascular Disorders 2019 19:134

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  26. Content type: Research article

    The association between mean platelet volume (MPV) and coronary plaque vulnerability in patients with non-ST-elevation ACS (NSTE-ACS) has not been investigated. We performed a retrospective study to evaluate t...

    Authors: Jun Wang, Xing Li, Jun Pu, Siyu Jin, Lu Jia, Xiaomei Li, Fen Liu and Yining Yang

    Citation: BMC Cardiovascular Disorders 2019 19:128

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  27. Content type: Research article

    Emerging evidence suggests that patients with coronary artery disease carry an increased risk of developing malignancy, with deleterious effects on long-term prognosis. Our aim was to ascertain whether baselin...

    Authors: Giuseppe Berton, Rocco Cordiano, Fiorella Cavuto, Francesco Bagato, Heba Talat Mahmoud and Mattia Pasquinucci

    Citation: BMC Cardiovascular Disorders 2019 19:119

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  28. Content type: Research article

    Myocardial ischemia-reperfusion (IR) injury is a leading cause of death all over the world, so developing practical approaches to promote cardioprotection against IR injury is essential. Exercise training is a...

    Authors: Maral Ramez, Hamid Rajabi, Fatemeh Ramezani, Nasim Naderi, Amir Darbandi-Azar and Farinaz Nasirinezhad

    Citation: BMC Cardiovascular Disorders 2019 19:118

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  29. Content type: Research article

    Warfarin is the standard of care and NOAC (Novel oral anticoagulants) are a group of newer drugs for such purposes. NOAC has a generally better profile (Clear interaction, less side effect, require less monito...

    Authors: Qiyu He, Chun-Yat Sze, Tin-Yau Shum, Guang Hao, Nga-Yin Belinda Wong, Tat-Hang Sin, Wei Wei and Sujian Xia

    Citation: BMC Cardiovascular Disorders 2019 19:113

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  30. Content type: Research article

    Inflammation in myocardial infarction has a complex immunogenic origin and is suspected to be closely involved in its aetio-pathogenesis as well as outcome. In this study the objective was to further elucidate...

    Authors: Mitrakrishnan Rayno Navinan, Sepalika Mendis, Sumudu Wickramasinghe, Ambiga Kathirgamanathan, Tharanga Fernando and Jevon Yudhisdran

    Citation: BMC Cardiovascular Disorders 2019 19:111

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  31. Content type: Research article

    The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the ...

    Authors: Guozhong Wang, Quanming Zhao, Qing Cheng, Xiaoxia Zhang, Lei Tian and Xiaofan Wu

    Citation: BMC Cardiovascular Disorders 2019 19:109

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  32. Content type: Research article

    Recent studies have indicated that monocyte chemoattractant protein-1 (MCP-1) plays an important role in the initiation and progression of ischaemic heart disease. However, no previous research has investigate...

    Authors: Yong Zhu, Chengping Hu, Yu Du, Jianwei Zhang, Jinxing Liu, Hongya Han and Yingxin Zhao

    Citation: BMC Cardiovascular Disorders 2019 19:107

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  33. Content type: Research article

    The diagnostic and prognostic utility of risk factors proposed by the 2012 American Heart Association and American College of Cardiology Foundation (AHA/ACCF) Scientific Statement on the cardiac assessment of ...

    Authors: Sarah Alexander, Meron Teshome, Hena Patel, Edie Y. Chan and Rami Doukky

    Citation: BMC Cardiovascular Disorders 2019 19:102

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  34. Content type: Research article

    The association between dental health and coronary artery disease (CAD) remains a topic of debate. This study aimed to investigate the association between dental health and obstructive CAD using multiple denta...

    Authors: Ho Lee, Hack-Lyoung Kim, Kwang Nam Jin, Sohee Oh, Yoon-Sic Han, Da-Un Jung, Hye-Young Sim, Hee-Sun Kim, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo and Myung-A Kim

    Citation: BMC Cardiovascular Disorders 2019 19:98

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  35. Content type: Research article

    Percutaneous coronary intervention (PCI) for bifurcation lesions has often been challenging for Interventionists. Application of the correct intra-procedural technique is vital to generate beneficial outcomes ...

    Authors: Feng Huang and Zu-chun Luo

    Citation: BMC Cardiovascular Disorders 2019 19:93

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  36. Content type: Research article

    The best strategy for the treatment of the non-infarct artery in patients with ST-elevation myocardial infarction (STEMI) and multivessel disease (MVD) undergoing primary percutaneous coronary intervention (PC...

    Authors: Haiyan Xu, Xiwen Zhang, Jiangjin Li, Hailang Liu, Xiao Hu and Jing Yang

    Citation: BMC Cardiovascular Disorders 2019 19:91

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  37. Content type: Research article

    The role of intravenous hydration at the time of primary percutaneous intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) remains unclear. Guidelines are vague, supported by low level evi...

    Authors: Yong Liu, Daqing Hong, Amanda Ying Wang, Rui Guo, Brendan Smyth, Jin Liu, Guoli Sun, Shiqun Chen, Ning Tan, Meg Jardine, David Brieger, Ahmed Shaman, Shariful Islam, Jiyan Chen and Martin Gallagher

    Citation: BMC Cardiovascular Disorders 2019 19:87

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  38. Content type: Case report

    There are three major mechanical complications after acute myocardial infarction: left ventricular free-wall rupture, ventricular septum rupture and acute mitral valve regurgitation. The left ventricular free-...

    Authors: Dulman O. Pineda-De Paz, Jorge E. Hernández-del Rio, Christian González-Padilla, Ramón M. Esturau-Santaló, Joseph Romero-Palafox, Fernando Grover-Paez and David Cardona-Muller

    Citation: BMC Cardiovascular Disorders 2019 19:80

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  39. Content type: Case report

    Takayasu arteritis is a rare systemic vasculitis, which affects the aorta and its major branches, especially in young females. Diagnosis and treatment for Takayasu arteritis with coronary stenosis are importan...

    Authors: Tetsuro Yokokawa, Hiroyuki Kunii, Takashi Kaneshiro, Shohei Ichimura, Akiomi Yoshihisa, Makiko Yashiro Furuya, Tomoyuki Asano, Kazuhiko Nakazato, Takafumi Ishida, Kiyoshi Migita and Yasuchika Takeishi

    Citation: BMC Cardiovascular Disorders 2019 19:79

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  40. Content type: Research article

    The usefulness of the CHA2DS2-VASC risk score (CVRS) in predicting the occurrence of contrast-induced nephropathy (CIN) among patients with chronic total occlusion (CTO) undergoing percutaneous coronary interv...

    Authors: Yong Wang, Hong-wei Zhao, Xiao-jiao Zhang, Bao-jun Chen, Guo-ning Yu, Ai-jie Hou and Bo Luan

    Citation: BMC Cardiovascular Disorders 2019 19:74

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  41. Content type: Research article

    Patients with established coronary artery disease (CAD) have an increased risk of new cardiovascular events. An underuse of secondary preventive drugs has been observed, and many patients may not attain the tr...

    Authors: Jarle Jortveit, Sigrun Halvorsen, Anete Kaldal, Are Hugo Pripp, Ragna Elise S. Govatsmark and Jørund Langørgen

    Citation: BMC Cardiovascular Disorders 2019 19:71

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  42. Content type: Technical advance

    Methodological information acknowledging safety of cardiac patients in controlled medical experiments are lacking. The descriptive report presents one good practice for considering safety in a randomized contr...

    Authors: Tiina M. Ikäheimo, Miia Länsitie, Rasmus Valtonen, Heidi E. Hintsala, Niilo Ryti, Juha Perkiömäki, Matti Mäntysaari, Arto J. Hautala and Jouni J. K. Jaakkola

    Citation: BMC Cardiovascular Disorders 2019 19:69

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  43. Content type: Research article

    Major in-hospital mortality rate in patients with ST-segment Elevation Myocardial Infarction (STEMI) in Sub-Saharan Africa has been reported. Data on follow-up in these patients with STEMI are scarce. We aimed...

    Authors: Hermann Yao, Arnaud Ekou, Aurore Hadéou, Jean-Jacques N’Djessan, Isabelle Kouamé and Roland N’Guetta

    Citation: BMC Cardiovascular Disorders 2019 19:65

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  44. Content type: Research article

    Whether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphi...

    Authors: Xia Zhang, Yan Jun Cao, Hong Yu Zhang, Hongliang Cong and Jian Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:63

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  45. Content type: Research article

    BRS represent a new approach to treating coronary artery disease. Beneficial properties of BRS regarding the restoration of vasomotility after resorption make them attractive devices in CTO revascularization. ...

    Authors: Alberto Polimeni, Remzi Anadol, Thomas Münzel, Martin Geyer, Salvatore De Rosa, Ciro Indolfi and Tommaso Gori

    Citation: BMC Cardiovascular Disorders 2019 19:59

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  46. Content type: Research article

    Both nonthyroidal illness syndrome and renal dysfunction are associated with increased mortality risk in acute myocardial infarction (AMI). However, it is unclear whether combined NTIS and renal dysfunction fu...

    Authors: Jun-Wei Wang, Ying Ren, Zhi-Gang Lu, Jing Gao, Cui-Chun Zhao, Lian-Xi Li and Meng Wei

    Citation: BMC Cardiovascular Disorders 2019 19:50

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  47. Content type: Research article

    Approximately 30–50% patients with acute ST-segment elevation myocardial infarction (STMEI) were found to have non-infarct-related coronary artery (IRA) disease, which was significantly associated with worse p...

    Authors: Li-jie Wang, Shuo Han, Xiao-Hong Zhang and Yuan-Zhe Jin

    Citation: BMC Cardiovascular Disorders 2019 19:49

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  48. Content type: Research article

    Although numerous reports suggest sex-related differences in atherosclerosis, limited data describing gender-associated differences in plaque morphology and composition are currently available. The aim of the ...

    Authors: Jiangtian Tian, Xuedong Wang, Jinwei Tian and Bo Yu

    Citation: BMC Cardiovascular Disorders 2019 19:45

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