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Coronary artery disease

Section edited by Fabrizio D'ascenzo
This section concerns all aspects of coronary artery disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. Content type: Research article

    Emerging evidence suggests that patients with coronary artery disease carry an increased risk of developing malignancy, with deleterious effects on long-term prognosis. Our aim was to ascertain whether baselin...

    Authors: Giuseppe Berton, Rocco Cordiano, Fiorella Cavuto, Francesco Bagato, Heba Talat Mahmoud and Mattia Pasquinucci

    Citation: BMC Cardiovascular Disorders 2019 19:119

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  2. Content type: Research article

    Myocardial ischemia-reperfusion (IR) injury is a leading cause of death all over the world, so developing practical approaches to promote cardioprotection against IR injury is essential. Exercise training is a...

    Authors: Maral Ramez, Hamid Rajabi, Fatemeh Ramezani, Nasim Naderi, Amir Darbandi-Azar and Farinaz Nasirinezhad

    Citation: BMC Cardiovascular Disorders 2019 19:118

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  3. Content type: Research article

    Warfarin is the standard of care and NOAC (Novel oral anticoagulants) are a group of newer drugs for such purposes. NOAC has a generally better profile (Clear interaction, less side effect, require less monito...

    Authors: Qiyu He, Chun-Yat Sze, Tin-Yau Shum, Guang Hao, Nga-Yin Belinda Wong, Tat-Hang Sin, Wei Wei and Sujian Xia

    Citation: BMC Cardiovascular Disorders 2019 19:113

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  4. Content type: Research article

    Inflammation in myocardial infarction has a complex immunogenic origin and is suspected to be closely involved in its aetio-pathogenesis as well as outcome. In this study the objective was to further elucidate...

    Authors: Mitrakrishnan Rayno Navinan, Sepalika Mendis, Sumudu Wickramasinghe, Ambiga Kathirgamanathan, Tharanga Fernando and Jevon Yudhisdran

    Citation: BMC Cardiovascular Disorders 2019 19:111

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  5. Content type: Research article

    The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the ...

    Authors: Guozhong Wang, Quanming Zhao, Qing Cheng, Xiaoxia Zhang, Lei Tian and Xiaofan Wu

    Citation: BMC Cardiovascular Disorders 2019 19:109

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  6. Content type: Research article

    Recent studies have indicated that monocyte chemoattractant protein-1 (MCP-1) plays an important role in the initiation and progression of ischaemic heart disease. However, no previous research has investigate...

    Authors: Yong Zhu, Chengping Hu, Yu Du, Jianwei Zhang, Jinxing Liu, Hongya Han and Yingxin Zhao

    Citation: BMC Cardiovascular Disorders 2019 19:107

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  7. Content type: Research article

    The diagnostic and prognostic utility of risk factors proposed by the 2012 American Heart Association and American College of Cardiology Foundation (AHA/ACCF) Scientific Statement on the cardiac assessment of ...

    Authors: Sarah Alexander, Meron Teshome, Hena Patel, Edie Y. Chan and Rami Doukky

    Citation: BMC Cardiovascular Disorders 2019 19:102

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  8. Content type: Research article

    The association between dental health and coronary artery disease (CAD) remains a topic of debate. This study aimed to investigate the association between dental health and obstructive CAD using multiple denta...

    Authors: Ho Lee, Hack-Lyoung Kim, Kwang Nam Jin, Sohee Oh, Yoon-Sic Han, Da-Un Jung, Hye-Young Sim, Hee-Sun Kim, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo and Myung-A Kim

    Citation: BMC Cardiovascular Disorders 2019 19:98

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  9. Content type: Research article

    Percutaneous coronary intervention (PCI) for bifurcation lesions has often been challenging for Interventionists. Application of the correct intra-procedural technique is vital to generate beneficial outcomes ...

    Authors: Feng Huang and Zu-chun Luo

    Citation: BMC Cardiovascular Disorders 2019 19:93

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  10. Content type: Research article

    The best strategy for the treatment of the non-infarct artery in patients with ST-elevation myocardial infarction (STEMI) and multivessel disease (MVD) undergoing primary percutaneous coronary intervention (PC...

    Authors: Haiyan Xu, Xiwen Zhang, Jiangjin Li, Hailang Liu, Xiao Hu and Jing Yang

    Citation: BMC Cardiovascular Disorders 2019 19:91

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  11. Content type: Research article

    The role of intravenous hydration at the time of primary percutaneous intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) remains unclear. Guidelines are vague, supported by low level evi...

    Authors: Yong Liu, Daqing Hong, Amanda Ying Wang, Rui Guo, Brendan Smyth, Jin Liu, Guoli Sun, Shiqun Chen, Ning Tan, Meg Jardine, David Brieger, Ahmed Shaman, Shariful Islam, Jiyan Chen and Martin Gallagher

    Citation: BMC Cardiovascular Disorders 2019 19:87

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  12. Content type: Case report

    There are three major mechanical complications after acute myocardial infarction: left ventricular free-wall rupture, ventricular septum rupture and acute mitral valve regurgitation. The left ventricular free-...

    Authors: Dulman O. Pineda-De Paz, Jorge E. Hernández-del Rio, Christian González-Padilla, Ramón M. Esturau-Santaló, Joseph Romero-Palafox, Fernando Grover-Paez and David Cardona-Muller

    Citation: BMC Cardiovascular Disorders 2019 19:80

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  13. Content type: Case report

    Takayasu arteritis is a rare systemic vasculitis, which affects the aorta and its major branches, especially in young females. Diagnosis and treatment for Takayasu arteritis with coronary stenosis are importan...

    Authors: Tetsuro Yokokawa, Hiroyuki Kunii, Takashi Kaneshiro, Shohei Ichimura, Akiomi Yoshihisa, Makiko Yashiro Furuya, Tomoyuki Asano, Kazuhiko Nakazato, Takafumi Ishida, Kiyoshi Migita and Yasuchika Takeishi

    Citation: BMC Cardiovascular Disorders 2019 19:79

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  14. Content type: Research article

    The usefulness of the CHA2DS2-VASC risk score (CVRS) in predicting the occurrence of contrast-induced nephropathy (CIN) among patients with chronic total occlusion (CTO) undergoing percutaneous coronary interv...

    Authors: Yong Wang, Hong-wei Zhao, Xiao-jiao Zhang, Bao-jun Chen, Guo-ning Yu, Ai-jie Hou and Bo Luan

    Citation: BMC Cardiovascular Disorders 2019 19:74

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  15. Content type: Research article

    Patients with established coronary artery disease (CAD) have an increased risk of new cardiovascular events. An underuse of secondary preventive drugs has been observed, and many patients may not attain the tr...

    Authors: Jarle Jortveit, Sigrun Halvorsen, Anete Kaldal, Are Hugo Pripp, Ragna Elise S. Govatsmark and Jørund Langørgen

    Citation: BMC Cardiovascular Disorders 2019 19:71

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  16. Content type: Technical advance

    Methodological information acknowledging safety of cardiac patients in controlled medical experiments are lacking. The descriptive report presents one good practice for considering safety in a randomized contr...

    Authors: Tiina M. Ikäheimo, Miia Länsitie, Rasmus Valtonen, Heidi E. Hintsala, Niilo Ryti, Juha Perkiömäki, Matti Mäntysaari, Arto J. Hautala and Jouni J. K. Jaakkola

    Citation: BMC Cardiovascular Disorders 2019 19:69

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  17. Content type: Research article

    Major in-hospital mortality rate in patients with ST-segment Elevation Myocardial Infarction (STEMI) in Sub-Saharan Africa has been reported. Data on follow-up in these patients with STEMI are scarce. We aimed...

    Authors: Hermann Yao, Arnaud Ekou, Aurore Hadéou, Jean-Jacques N’Djessan, Isabelle Kouamé and Roland N’Guetta

    Citation: BMC Cardiovascular Disorders 2019 19:65

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  18. Content type: Research article

    Whether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphi...

    Authors: Xia Zhang, Yan Jun Cao, Hong Yu Zhang, Hongliang Cong and Jian Zhang

    Citation: BMC Cardiovascular Disorders 2019 19:63

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  19. Content type: Research article

    BRS represent a new approach to treating coronary artery disease. Beneficial properties of BRS regarding the restoration of vasomotility after resorption make them attractive devices in CTO revascularization. ...

    Authors: Alberto Polimeni, Remzi Anadol, Thomas Münzel, Martin Geyer, Salvatore De Rosa, Ciro Indolfi and Tommaso Gori

    Citation: BMC Cardiovascular Disorders 2019 19:59

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  20. Content type: Research article

    Both nonthyroidal illness syndrome and renal dysfunction are associated with increased mortality risk in acute myocardial infarction (AMI). However, it is unclear whether combined NTIS and renal dysfunction fu...

    Authors: Jun-Wei Wang, Ying Ren, Zhi-Gang Lu, Jing Gao, Cui-Chun Zhao, Lian-Xi Li and Meng Wei

    Citation: BMC Cardiovascular Disorders 2019 19:50

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  21. Content type: Research article

    Approximately 30–50% patients with acute ST-segment elevation myocardial infarction (STMEI) were found to have non-infarct-related coronary artery (IRA) disease, which was significantly associated with worse p...

    Authors: Li-jie Wang, Shuo Han, Xiao-Hong Zhang and Yuan-Zhe Jin

    Citation: BMC Cardiovascular Disorders 2019 19:49

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  22. Content type: Research article

    Although numerous reports suggest sex-related differences in atherosclerosis, limited data describing gender-associated differences in plaque morphology and composition are currently available. The aim of the ...

    Authors: Jiangtian Tian, Xuedong Wang, Jinwei Tian and Bo Yu

    Citation: BMC Cardiovascular Disorders 2019 19:45

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  23. Content type: Case report

    Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited myocardial disease characterized by fibrofatty replacement and ventricular arrhythmias. ARVC is believed to be a disease of the young, wit...

    Authors: Yusuke Adachi, Takekuni Hayashi, Takeshi Mitsuhashi, Kenichi Sakakura, Yoko Yamada, Yuko Wada, Minoru Horie, Shin-ichi Momomura and Hideo Fujita

    Citation: BMC Cardiovascular Disorders 2019 19:41

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  24. Content type: Research article

    The heterogeneity of risk in patients with diabetes mellitus (DM) is acknowledged in new guidelines promulgating different treatment recommendations for diabetics at low cardiac risk. We performed a retrospect...

    Authors: Junjie Yang, Guanhua Dou, Christian Tesche, Carlo N. De Cecco, Brian E. Jacobs, U. Joseph Schoepf and Yundai Chen

    Citation: BMC Cardiovascular Disorders 2019 19:39

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  25. Content type: Research article

    Percutaneous coronary intervention (PCI) has been associated with contrast-induced nephropathy (CIN) at a rate that varies depending on the patient’s risk factors. This study was conducted to evaluate the pred...

    Authors: Zheng-rong Xu, Jun Chen, Yuan-hui Liu, Yong Liu and Ning Tan

    Citation: BMC Cardiovascular Disorders 2019 19:36

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  26. Content type: Research article

    Previous studies have found a connection between left coronary artery dominance and worse prognoses in patient with acute coronary syndrome, which remains a predominant cause of morbidity and mortality globall...

    Authors: Li Wang, Jiamei Li, Ya Gao, Ruohan Li, Jingjing Zhang, Dan Su, Tao Wang, Guang Yang and Xiaochuang Wang

    Citation: BMC Cardiovascular Disorders 2019 19:35

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  27. Content type: Study protocol

    Heart failure (HF) is a major chronic illness and results in high morbidity and mortality. The most frequent cause of HF with reduced ejection fraction (HFREF) is coronary artery disease (CAD). Although revasc...

    Authors: L. Pleva, P. Kukla, K. Vítková and V. Procházka

    Citation: BMC Cardiovascular Disorders 2019 19:32

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  28. Content type: Case report

    Obstructive coronary artery disease is found in approximately 97% of patients presenting with ST-elevation myocardial infarction and 92% of patients with non ST-elevation myocardial infarction (Bainey KR, Wels...

    Authors: M. Piels, T. Faes and J. Vainer

    Citation: BMC Cardiovascular Disorders 2019 19:28

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2019 19:70

  29. Content type: Research article

    Metabolic syndrome (MetS) is a prevalent risk factor for coronary artery disease progression. Past studies have shown that MetS and its components tends to increase mortality after coronary artery bypass graft...

    Authors: Shuangkun Chen, Jiahui Li, Qianzhen Li, Zhihuang Qiu, Xijie Wu and Liangwan Chen

    Citation: BMC Cardiovascular Disorders 2019 19:25

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  30. Content type: Research article

    Data on bioresorbable vascular scaffolds (BVS) for the treatment of long lesions are limited. We studied the use of BVS-Absorb in routine clinical practice and compared the outcome of long lesions with short l...

    Authors: Christine Reichart, Jochen Wöhrle, Sinisa Markovic, Wolfgang Rottbauer and Julia Seeger

    Citation: BMC Cardiovascular Disorders 2019 19:22

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  31. Content type: Research article

    Kawasaki disease (KD) is an acute febrile childhood systemic vasculitis that disturbs coronary arteries. The pathogenesis remains unknown. The study of phosphorylated proteins helps to elucidate the relevant p...

    Authors: Shui-Ming Li, Wan-Ting Liu, Fang Yang, Qi-Jian Yi, Shuai Zhang and Hong-Ling Jia

    Citation: BMC Cardiovascular Disorders 2019 19:21

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  32. Content type: Research article

    Coronary artery disease accelerates heart failure progression, leading to poor prognosis and a substantial increase in morbidity and mortality. This study was aimed to assess the impact of coronary artery dise...

    Authors: Qi Zhao, Li Wang, Paul A. Kurlansky, Jeff Schein, Onur Baser and Jeffrey S. Berger

    Citation: BMC Cardiovascular Disorders 2019 19:19

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  33. Content type: Case report

    Hypertrophic cardiomyopathy (HCM) is a myocardial disease. However, the coexistence of HCM with muscular ventricular septal defect (VSD), especially those with both incomplete spontaneous closure and coronary ...

    Authors: Guang-mei Zheng, Jiao Bai, Jun-ming Tang, Fang-cheng Zhu and Hong-xia Jing

    Citation: BMC Cardiovascular Disorders 2019 19:16

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  34. Content type: Debate

    In the standard ECG display, limb leads are presented in a non-anatomical sequence: I, II, III, aVR, aVL, aVF. The Cabrera system is a display format which instead presents the limb leads in a cranial/left-to-...

    Authors: T. Lindow, Y. Birnbaum, K. Nikus, A. Maan, U. Ekelund and O. Pahlm

    Citation: BMC Cardiovascular Disorders 2019 19:13

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  35. Content type: Research article

    Percutaneous coronary interventions (PCI) of bifurcation lesions is technically challenging and associated with lower success rates and higher frequency of adverse outcomes. In the present study, we aimed to e...

    Authors: Wenduo Zhang, Fusui Ji, Xue Yu and Xinyue Wang

    Citation: BMC Cardiovascular Disorders 2019 19:12

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  36. Content type: Research article

    Elevated plasma triglycerides (TGs) are widely used as a major cardiovascular risk predictor and are thought to play an important role in the progression of coronary heart disease (CHD). It has been demonstrat...

    Authors: Neda M. Bogari, Ashwag Aljohani, Amr A. Amin, Faisal A. Al-Allaf, Anas Dannoun, Mohiuddin M. Taher, Atalla Elsayed, Dareen ibrahim Rednah, Osama Elkhatee, Massimo Porqueddu, Francesco Alamanni, Soud Abdulraof A. Khogeer and Ahmed Fawzy

    Citation: BMC Cardiovascular Disorders 2019 19:2

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  37. Content type: Research article

    Klotho, possibly an age-regulating protein, is considered an important factor contributing to the lifespan and pathophysiology of hypertension and coronary artery disease (CAD). The present study was carried o...

    Authors: Hamed Akbari, Gholamreza Asadikaram, Hamid Aria, Saba Fooladi, Sina Vakili and Mohammad Masoumi

    Citation: BMC Cardiovascular Disorders 2018 18:237

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  38. Content type: Case report

    In the era of primary percutaneous coronary intervention (PPCI), the incidence of post-cardiac injury syndrome (PCIS) in patients with acute myocardial infarction (AMI) following PPCI has become less common. H...

    Authors: Yan Gao, Nanette H. Bishopric, Hong-wei Chen, Jiang-tao Li, Yu-lang Huang and He-xun Huang

    Citation: BMC Cardiovascular Disorders 2018 18:234

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  39. Content type: Study protocol

    Plaque composition and morphologic characteristics identified by virtual histology intravascular ultrasound (VH-IVUS) can determine plaques at increased risk of clinical events following percutaneous coronary ...

    Authors: Yin Liu, Hai-Bo Wang, Xiang Li, Jian-Yong Xiao, Ji-Xiang Wang, Kathleen H. Reilly, Bo Sun and Jing Gao

    Citation: BMC Cardiovascular Disorders 2018 18:233

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  40. Content type: Research article

    The prognostic significance of changes in mean platelet volume (MPV) during hospitalization in ST segment elevation myocardial infarction (STEMI) patients underwent primary percutaneous coronary intervention (...

    Authors: Eyup Avci, Tuncay Kiris, Aykan Çelik, Eser Variş, Fatma Kayaalti Esin, Diyar Köprülü and Hasan Kadi

    Citation: BMC Cardiovascular Disorders 2018 18:226

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  41. Content type: Research article

    Ticagrelor has been acknowledged as a new oral antagonist of P2Y12-adenosine diphosphate receptor, as a strategy with more rapid onset as well as more significant platelet inhibition function in acute coronary...

    Authors: Dong Wang, Xiao-Hong Yang, Ji-Dong Zhang, Rui-Bin Li, Min Jia and Xiao-Ran Cui

    Citation: BMC Cardiovascular Disorders 2018 18:217

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  42. Content type: Research article

    To decrease the morbidity burden of cardiovascular disease and to avoid the development of potentially preventable complications, early assessment and treatment of acute coronary syndrome (ACS) are important. ...

    Authors: Mats Holmberg, Henrik Andersson, Karin Winge, Camilla Lundberg, Thomas Karlsson, Johan Herlitz and Birgitta Wireklint Sundström

    Citation: BMC Cardiovascular Disorders 2018 18:216

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  43. Content type: Research article

    Obstructive sleep apnea (OSA) and insomnia are frequent sleep problems that are associated with poor prognosis in patients with coronary heart disease. The mechanisms linking poor sleep with an increased cardi...

    Authors: Roland von Känel, Mary Princip, Jean-Paul Schmid, Jürgen Barth, Hansjörg Znoj, Ulrich Schnyder and Rebecca E. Meister-Langraf

    Citation: BMC Cardiovascular Disorders 2018 18:213

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  44. Content type: Research article

    Compared to ST-segment elevation myocardial infarction (STEMI) patients who present at centres with catheterization facilities, those transferred for primary percutaneous coronary intervention (PCI) have subst...

    Authors: Oumin Shi, Anam M. Khan, Mohammad R. Rezai, Cynthia A. Jackevicius, Jafna Cox, Clare L. Atzema, Dennis T. Ko, Thérèse A. Stukel, Laurie J. Lambert, Madhu K. Natarajan, Zhi-jie Zheng and Jack V. Tu

    Citation: BMC Cardiovascular Disorders 2018 18:204

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  45. Content type: Research article

    We conducted a randomized controlled trial to investigate whether an additional platelet inhibition with tirofiban would reduce the extent of myocardial damage and prevent periprocedural myonecrosis in patient...

    Authors: Wonjae Lee, Jung-Won Suh, Jin Joo Park, Chang-Hwan Yoon, Young-Seok Cho, Tae-Jin Youn and In-Ho Chae

    Citation: BMC Cardiovascular Disorders 2018 18:201

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  46. Content type: Research article

    Receptor tyrosine kinases (RTK) are potential targets for the treatment of ischemic heart disease. The human RTK family consists of 55 members, most of which have not yet been characterized for expression or a...

    Authors: Juho Heliste, Anne Jokilammi, Ilkka Paatero, Deepankar Chakroborty, Christoffer Stark, Timo Savunen, Maria Laaksonen and Klaus Elenius

    Citation: BMC Cardiovascular Disorders 2018 18:196

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