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Coronary artery disease

This section concerns all aspects of coronary artery disease including but not limited to: prevention, diagnosis and management, as well as related molecular genetics, and pathophysiology.

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  1. The population of adults with congenital heart disease (CHD) is growing, and increasingly more patients with CHD reach older ages. Patients with CHD are at an increased risk of myocardial infarction (MI) with ...

    Authors: Maria Fedchenko, Zacharias Mandalenakis, Görel Hultsberg-Olsson, Helena Dellborg, Peter Eriksson and Mikael Dellborg

    Citation: BMC Cardiovascular Disorders 2020 20:460

    Content type: Research article

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  2. No-reflow occurs in 3–4% of all percutaneous coronary interventions (PCIs) and has a strong negative impact on clinical outcomes of acute coronary syndrome (ACS). Therefore, the discovery of a biomarker that c...

    Authors: Nian-Peng Song, Xiao-Wen Zhen, Liu-dong Li, Lin Zhong, Hua Wang and Yi An

    Citation: BMC Cardiovascular Disorders 2020 20:443

    Content type: Research article

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  3. Myocardial perfusion single-photon emission computed tomography (SPECT) imaging with stress is a useful examination for detecting coronary artery disease. Since the presence of artifacts is remaining challenge...

    Authors: Yukinori Shinoda, Koichi Tachibana, Tomoko Minamisaka, Hidetada Fukuoka, Hirooki Inui, Keisuke Ueno, Soki Inoue, Kentaro Mine, Kumpei Ueda and Shiro Hoshida

    Citation: BMC Cardiovascular Disorders 2020 20:438

    Content type: Research article

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  4. To evaluate the coronary plaque characteristics of coronary arteries using computed tomography angiography (CTA) in order to assess the risk of coronary artery disease and the relevance of high sensitivity C r...

    Authors: Hai-Ting Zhou, De-Li Zhao, Guo-Kun Wang, Tian-Zuo Wang, Hong-Wei Liang and Jin-Ling Zhang

    Citation: BMC Cardiovascular Disorders 2020 20:435

    Content type: Research article

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  5. This meta-analysis aimed to compare the effects of prasugrel and ticagrelor on high (HTPR) and low on-treatment platelet reactivity (LTPR) in patients with acute coronary syndrome (ACS).

    Authors: Mingxiang Wen, Yaqi Li, Xiang Qu, Yanyan Zhu, Lingfang Tian, Zhongqin Shen, Xiulin Yang and Xianqing Shi

    Citation: BMC Cardiovascular Disorders 2020 20:430

    Content type: Research article

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  6. This study was to explore the influencing factors of atherosclerotic plaque formation and stability in patients with asymptomatic carotid atherosclerotic plaques, so as to identify the vulnerable plaques at ea...

    Authors: Yungen Jiao, Yahong Qin, Zhengang Zhang, Hao Zhang, Haiwei Liu and Chen Li

    Citation: BMC Cardiovascular Disorders 2020 20:429

    Content type: Research article

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  7. The predictors of left ventricular thrombus (LVT) formation are not well defined in the contemporary era, especially in those patients at high risk. We aimed to evaluate whether the platelet/lymphocyte ratio (...

    Authors: Qian Zhang, Daoyuan Si, Zhongfan Zhang, Chengbing Wang, Haikuo Zheng, Shouping Li, Shijian Huang and Wenqi Zhang

    Citation: BMC Cardiovascular Disorders 2020 20:428

    Content type: Research article

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  8. Previous studies focus on one or several serum biomarkers and the risk of cardiovascular disease (CVD). This study aims to investigate the association of multiple serum biomarkers and the risk of CVD and evalu...

    Authors: Huichen Yao, Chenyang Hou, Weihua Liu, Jihu Yi, Wencong Su and Qingzhi Hou

    Citation: BMC Cardiovascular Disorders 2020 20:426

    Content type: Research article

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  9. To determine whether intermittent hypoxia (IH) can reduce the infarct size (IS) after acute myocardial infarction (AMI) in rats.

    Authors: Ke Hu, Wei Deng, Jing Yang, Yu Wei, Chaolin Wen, Xingsheng Li, Qingwei Chen, Dazhi Ke and Guiqiong Li

    Citation: BMC Cardiovascular Disorders 2020 20:422

    Content type: Research article

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  10. Acute coronary syndrome (ACS) is a rare, but serious complication of infective endocarditis, and diagnosis can be challenging given clinical overlap with other syndromes. A rare cause of ACS in infective endoc...

    Authors: Alexander Bolton, Georges Hajj, Laila Payvandi and Christopher Komanapalli

    Citation: BMC Cardiovascular Disorders 2020 20:412

    Content type: Case report

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  11. Premature coronary artery disease is one of the most pressing global issues in modern cardiology. The aim of the study was to investigate the role of family history of premature cardiovascular disease (CVD) in...

    Authors: Michał Ambroziak, Katarzyna Niewczas-Wieprzowska, Agnieszka Maicka and Andrzej Budaj

    Citation: BMC Cardiovascular Disorders 2020 20:410

    Content type: Research article

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  12. Cardiac rupture (CR) is a fatal complication of ST-elevation myocardial infarction (STEMI) with its incidence markedly declined in the recent decades. However, clinical features of CR patients now and the effe...

    Authors: Qun Lu, Ping Liu, Jian-Hua Huo, Yan-Ni Wang, Ai-Qun Ma, Zu-Yi Yuan, Xiao-Jun Du and Ling Bai

    Citation: BMC Cardiovascular Disorders 2020 20:409

    Content type: Research article

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    The Correction to this article has been published in BMC Cardiovascular Disorders 2020 20:441

  13. N-acetylneuraminic acid (Neu5Ac) is a functional metabolite involved in coronary artery disease (CAD). We aimed to evaluate the relationship between serum Neu5Ac and the risk and prognosis of acute coronary sy...

    Authors: Miao-Nan Li, Shao-Huan Qian, Zhuo-Ya Yao, Sheng-Ping Ming, Xiao-Jun Shi, Ping-Fang Kang, Ning-Ru Zhang, Xiao-Jing Wang, Da-Sheng Gao, Qing Gao, Heng Zhang and Hong-Ju Wang

    Citation: BMC Cardiovascular Disorders 2020 20:404

    Content type: Research article

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  14. Dysfunction in the late Endothelial Progenitor Cells (EPCs) is responsible for endothelial repair in patients with Coronary Artery Disease (CAD), and the shear stress is beneficial for EPCs function. However, ...

    Authors: Hua Zhou, Qiang Tu, Yan Zhang, Hua Qiang Xie, Qing Yun Shuai, Xiao Chuan Huang, Jie Fu and Zheng Cao

    Citation: BMC Cardiovascular Disorders 2020 20:403

    Content type: Research article

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  15. Risk stratification is recommended as the key step to prevent contrast-associated acute kidney injury (CA-AKI) among at-risk patients following coronary angiography (CAG) and/or percutaneous coronary intervent...

    Authors: Liwei Liu, Jin Liu, Li Lei, Bo Wang, Guoli Sun, Zhaodong Guo, Yibo He, Feier Song, Zhubin Lun, Bowen Liu, Guanzhong Chen, Shiqun Chen, Yongquan Yang, Yong Liu and Jiyan Chen

    Citation: BMC Cardiovascular Disorders 2020 20:399

    Content type: Research article

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  16. Iatrogenic acute aortic dissection (AD) is an extremely rare but devastating complication during cardiac catheterization. It can be treated conservatively if it develops in a retrograde form or manifests as an...

    Authors: Kihyun Kim, Yeon Seong Kim, Yeongmin Woo and Sang-Yong Yoo

    Citation: BMC Cardiovascular Disorders 2020 20:398

    Content type: Case report

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  17. Suboptimal coronary blood flow after primary percutaneous coronary intervention (PCI) is a complex multifactorial phenomenon. Although extensively studied, defined modifiable risk factors and efficient managem...

    Authors: Karim Elakabawi, Xin Huang, Sardar Ali Shah, Hameed Ullah, Gary S. Mintz, Zuyi Yuan and Ning Guo

    Citation: BMC Cardiovascular Disorders 2020 20:391

    Content type: Research article

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  18. Platelet activation plays a crucial role in the pathogenesis of coronary artery disease (CAD). Platelet P-selectin (CD62P) is a classic platelet activation indicator on the platelet surface, and soluble TREM-l...

    Authors: Li Shen, Tianlun Yang, Ke Xia, Zhiqiang Yan, Juanjuan Tan, Lei Li, Yingchun Qin and Wei Shi

    Citation: BMC Cardiovascular Disorders 2020 20:387

    Content type: Research article

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  19. Myocardial bridge (MB) often an inoffensive condition that goes in one or more of the coronary arteries through the heart muscle instead of lying on its surface. MBs sometimes leads to myocardial ischemic symp...

    Authors: Xingwei He, Zakarya Ahmed, Xin Liu, Chang Xu and Hesong Zeng

    Citation: BMC Cardiovascular Disorders 2020 20:385

    Content type: Case report

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  20. The discrepancy between glycosylated hemoglobin (HbA1c) and fasting plasma glucose (FPG) in clinical practice may be related to factors such as acute stress, renal dysfunction, and anemia, and its relationship wi...

    Authors: Nan Ye, Lijiao Yang, Guoqin Wang, Weijing Bian, Fengbo Xu, Changsheng Ma, Dong Zhao, Jing Liu, Yongchen Hao, Jun Liu, Na Yang and Hong Cheng

    Citation: BMC Cardiovascular Disorders 2020 20:380

    Content type: Research article

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  21. The association of myocardial bridge (MB) with cardiovascular risk and the possible cardiovascular risk factors remain unclear. This study aimed to explore the clinical characteristics and related factors of c...

    Authors: Wen Gao, Jiaxi Zhang, Fei Duan, Shujun Guo, Chun Chen, Liping Du, Jianquan Zhao and Zhihong Zhou

    Citation: BMC Cardiovascular Disorders 2020 20:371

    Content type: Research article

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  22. Cardiac rehabilitation is effective after coronary heart disease (CHD). However, risk factors remain, and patients report fear for recurrence during recovery. Problem-based learning is a pedagogical method, wh...

    Authors: Anita Kärner Köhler, Tiny Jaarsma, Pia Tingström and Staffan Nilsson

    Citation: BMC Cardiovascular Disorders 2020 20:370

    Content type: Research article

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  23. Computed tomography feature tracking (CT-FT) has emerged as a valuable method for the assessment of cardiac function. However, no studies have investigated the usefulness of CT-derived assessments of left vent...

    Authors: Xiaoyu Han, Yukun Cao, Zhiguo Ju, Jia Liu, Na Li, Yumin Li, Tong Liu, Heshui Shi and Jin Gu

    Citation: BMC Cardiovascular Disorders 2020 20:362

    Content type: Research article

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  24. Neprilysin has an essential role in regulating fluid balance and vascular resistance, and neprilysin inhibitors have shown beneficial effects in patients with heart failure. However, the potential predictive v...

    Authors: Ik Jun Choi, Sungmin Lim, Youngdeok Hwang, Dongjae Lee, Won Jik Lee, Kwan Yong Lee, Mi-Jeong Kim and Doo Soo Jeon

    Citation: BMC Cardiovascular Disorders 2020 20:360

    Content type: Research article

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  25. Transradial access (TRA) has been considered as the default choice in cardiac catheterization. Although infrequent, vascular complications of this approach remain. Recently, the distal transradial approach (dT...

    Authors: Gaojun Cai, Haomin Huang, Feng Li, Ganwei Shi, Xiaolong Yu and Lei Yu

    Citation: BMC Cardiovascular Disorders 2020 20:356

    Content type: Review

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  26. While single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is a well-established noninvasive procedure for the evaluation of patients with coronary artery disease (CAD), it is ...

    Authors: Ronen Goldkorn, Alexey Naimushin, Eli Rozen and Dov Freimark

    Citation: BMC Cardiovascular Disorders 2020 20:354

    Content type: Research article

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  27. Self-care behavior has been reported to be below optimum in persons with heart failure, while the underlying decision making is not well understood. The Hot/Cool System model is a psychological model that may ...

    Authors: Mohammed Munther Al-Hammouri, Jehad A. Rababah, Lynne A. Hall, Debra K. Moser, Zainab Dawood, Wa’ed Jawhar and Ayat Alawawdeh

    Citation: BMC Cardiovascular Disorders 2020 20:349

    Content type: Research article

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  28. The no-reflow phenomenon (NRP) is a serious complication of primary percutaneous coronary intervention (PPCI) and is an independent predictor of poor prognosis. We aimed to find a simple but effective risk str...

    Authors: Qin-Yao Zhang, Shu-Mei Ma and Jia-Ying Sun

    Citation: BMC Cardiovascular Disorders 2020 20:346

    Content type: Research article

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  29. Evaluating knowledge in patients with coronary artery disease requires a specific measure. The aim of the present study was to translate and evaluate the CADE-Q in patients with coronary artery disease in Iran.

    Authors: Zahra Marofi, Razieh Bandari, Majideh Heravi-Karimooi, Nahid Rejeh and Ali Montazeri

    Citation: BMC Cardiovascular Disorders 2020 20:345

    Content type: Research article

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  30. De Winter syndrome accounts for approximately 2% of all patients with acute anterior myocardial infarction admitted to the emergency department, and is characterized by severe stenosis of the left anterior des...

    Authors: Bo Lu, Deyu Fu, Xunjie Zhou, Mingtai Gui, Lei Yao and Jianhua Li

    Citation: BMC Cardiovascular Disorders 2020 20:342

    Content type: Case report

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  31. The relationships of renal dysfunction (RD) and chronic kidney disease (CKD) with prognosis have been well established among non-ST elevation acute coronary syndrome (NSTE-ACS) patients who receive percutaneou...

    Authors: Wei Chen, Pengyuan Chen, Zhonghan Ni, Yuanhui Liu, Wei Guo, Lei Jiang, Xuebiao Wei, Jiyan Chen, Ning Tan, Pengcheng He and Yansong Guo

    Citation: BMC Cardiovascular Disorders 2020 20:341

    Content type: Research article

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  32. Coronary artery disease (CAD) is a complex disease resulting from the cumulative and interactive effects of large number of genes along with environmental exposure. Therefore, the present study was envisaged a...

    Authors: Jyotdeep Kour Raina, Minakashee Sharma, Rakesh Kumar Panjaliya, Vikas Dogra, Ashok Bakaya and Parvinder Kumar

    Citation: BMC Cardiovascular Disorders 2020 20:340

    Content type: Research article

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  33. The association between the lymphocyte-to-monocyte ratio (LMR) and prognosis in the patients with acute coronary syndrome (ACS) is not fully understood. We performed this systematic review and meta-analysis to...

    Authors: Xiao-Qing Quan, Run-Chang Wang, Qing Zhang, Cun-Tai Zhang and Lei Sun

    Citation: BMC Cardiovascular Disorders 2020 20:338

    Content type: Research article

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  34. High blood glucose impairs voltage-gated K+ (Kv) channel-mediated vasodilation in rat coronary artery smooth muscle cells (CSMCs) via oxidative stress. Advanced glycation end product (AGE) and receptor for AGE (R...

    Authors: Side Gao, Bing Hua, Qingbo Liu, Huirong Liu, Weiping Li and Hongwei Li

    Citation: BMC Cardiovascular Disorders 2020 20:337

    Content type: Research article

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  35. Patients with acute coronary syndrome (ACS) are at high risk of recurrent cardiovascular (CV) event. The European guidelines recommend low-density lipoprotein cholesterol (LDL-C) levels < 1.8 mmol/L and early ...

    Authors: Marie Skov Kristensen, Anders Green, Mads Nybo, Simone Møller Hede, Kristian Handberg Mikkelsen, Gunnar Gislason, Mogens Lytken Larsen and Annette Kjær Ersbøll

    Citation: BMC Cardiovascular Disorders 2020 20:336

    Content type: Research article

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  36. Peripheral arterial disease (PAD) is associated with considerable mortality and morbidity worldwide. The present study explored the risk factors for arterial calcification among the different sections of the l...

    Authors: Hankun Yan, Zhihui Chang and Zhaoyu Liu

    Citation: BMC Cardiovascular Disorders 2020 20:333

    Content type: Research article

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  37. Coronary artery ectasia (CAE) is an angiographic finding of abnormal coronary dilatation. Inflammation plays a major role in all phases of atherosclerosis. We investigated the relationship between CAE and seru...

    Authors: Cheng-Hui Fan, Ying Hao, Yong-Hua Liu, Xiao-Lin Li, Zhen-Hao Huang, Yu Luo and Rui-Lin Li

    Citation: BMC Cardiovascular Disorders 2020 20:330

    Content type: Research article

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  38. Coronary interventions in patients of achondroplasia have been reported rarely in the medical literature. Due to short stature and kyphoscoliosis, endovascular access (Cannulation) of the coronary arteries is ...

    Authors: Mustafa Ibrahiem Mohammed Ali, Ahmed Abdalazim Dafallah Albashir, Omer Ali Mohamed Ahmed Elawad and Makram Aboali Ebied Mohamed

    Citation: BMC Cardiovascular Disorders 2020 20:329

    Content type: Case report

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  39. As an inodilator, milrinone is commonly used for patients who undergo coronary artery bypass graft (CABG) surgery because of its effectiveness in decreasing the cardiac index and mitral regurgitation. The aim ...

    Authors: Yu-shan Ren, Lan-fang Li, Tao Peng, Yu-jun Tan, Ying Sun, Guo-liang Cheng, Gui-min Zhang and Jie Li

    Citation: BMC Cardiovascular Disorders 2020 20:328

    Content type: Research article

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  40. Provisional 1-stent technique is currently regarded as the default approach for the majority of bifurcation lesions. Nonetheless, 2-stent techniques may be required for complex bifurcations with high compromis...

    Authors: Hongbo Yang, Juying Qian, Zheyong Huang and Junbo Ge

    Citation: BMC Cardiovascular Disorders 2020 20:325

    Content type: Technical advance

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  41. Coronary artery disease (CAD) and atrial fibrillation (AF) frequently coexist in clinical practice, making it challenging for the treating physician to choose anticoagulation and antiplatelet therapies. The ai...

    Authors: Lili Wei, Enyong Su, Weili Liu, Wenlu Xing, Xinyun Liu, You Zhang, Shan Wang, Qianqian Cheng, Datun Qi and Chuanyu Gao

    Citation: BMC Cardiovascular Disorders 2020 20:323

    Content type: Research article

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  42. The study aimed to evaluate the application of intra-renal Doppler flow indices for the prediction of major adverse cardiac and cerebrovascular events (MACCE) during 24-month follow-up in patients with coronar...

    Authors: Maciej T. Wybraniec, Maria Bożentowicz-Wikarek, Magdalena Olszanecka-Glinianowicz, Jerzy Chudek and Katarzyna Mizia-Stec

    Citation: BMC Cardiovascular Disorders 2020 20:322

    Content type: Research article

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  43. Postcardiac injury syndrome (PCIS) is an inflammatory response syndrome characterized by pericardial effusion with or without pleural effusion; however, serious PCIS with peripheral hematoma of the ascending a...

    Authors: Yuan Wang, Wenkui Li, Chi Yuan and Hegui Wang

    Citation: BMC Cardiovascular Disorders 2020 20:317

    Content type: Case report

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  44. Left ventricular remodeling following ST-elevation myocardial infarction (STEMI) is associated with poor outcome, including heart failure (HF). Neprilysin inhibition leads to improved outcome in patients with ...

    Authors: Damien Legallois, Clémence Macquaire, Amir Hodzic, Stéphane Allouche, Ismaïl El Khouakhi, Alain Manrique, Paul Milliez, Eric Saloux and Farzin Beygui

    Citation: BMC Cardiovascular Disorders 2020 20:316

    Content type: Research article

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  45. Coronary artery aneurysm (CAA) is a potential cause of infarction. During the outbreak of coronavirus disease 2019 (COVID-19), home isolation and activity reduction can lead to hypercoagulability. Here, we rep...

    Authors: Wenshuai Ma, Chunyu Li, Wei Zhang, Zhaole Ji and Yan Li

    Citation: BMC Cardiovascular Disorders 2020 20:314

    Content type: Case report

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