The association of cardiac troponin and cardiovascular events in patients with concomitant heart failure preserved ejection fraction and atrial fibrillation

Table 4 Independent predictor of major adverse cardiac and cerebrovascular event in patients with AF combined HFpEF

	Unadjusted		Adjusted^a
	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
Age (per 1 year old)	1.04 (1.02–1.05)	< 0.01	1.03 (1.01–1.05)	0.01
Female	1.05 (0.72–1.54)	0.77	.	.
Hypertension	1.11 (0.75–1.65)	0.59	.	.
Diabetes mellitus	1.06 (0.71–1.58)	0.77	.	.
BMI ≥ 25	1.67 (1.02–2.75)	0.04	1.18 (0.71–1.98)	0.51
Previous heart failure	1.58 (1.11–2.47)	0.01	1.25 (0.84–1.88)	0.26
Previous stroke	1.10 (0.69–1.76)	0.66	.	.
Use of loop diuretics	1.39 (0.86–2.51)	0.08	1.22 (0.73–2.04)	0.43
Elevated hs-cTnI (≥ 99th percentile URL)	1.69 (1.10–2.61)	0.01	1.59 (1.03–2.47)	0.03

AF Atrial fibrillation, HFpEF Heart failure preserved ejection fraction, CI Confidence interval, BMI Body mass index, hs-cTnI high-sensitivity cardiac troponin I, URL Upper reference limit
^a Adjusted covariate included age, BMI ≥ 25, previous heart failure, use of loop diuretics and elevated hs-cTnI (≥ 99th percentile URL)

ISSN: 1471-2261